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Gene: Bcl6 (B cell leukemia/lymphoma 6) Mus musculus
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Symbol: Bcl6
Name: B cell leukemia/lymphoma 6
Description: Exhibits DNA binding activity and DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in several processes, including hemopoiesis; negative regulation of signal transduction; and regulation of lymphocyte activation. Localizes to the nucleus. Predicted to colocalize with the replication fork. Human ortholog(s) of this gene implicated in B-cell lymphoma and diffuse large B-cell lymphoma. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and liver and biliary system. Orthologous to human BCL6 (BCL6 transcription repressor); PARTICIPATES IN interleukin-4 signaling pathway; INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B-cell leukemia/lymphoma 5; B-cell leukemia/lymphoma 6; B-cell lymphoma 6 protein homolog; Bcl5
Orthologs:
Homo sapiens (human) : BCL6 (BCL6 transcription repressor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bcl6 (BCL6, transcription repressor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bcl6 (BCL6 transcription repressor)
Pan paniscus (bonobo/pygmy chimpanzee) : BCL6 (BCL6 transcription repressor)
Canis lupus familiaris (dog) : BCL6 (BCL6 transcription repressor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bcl6 (BCL6 transcription repressor)
Sus scrofa (pig) : BCL6 (BCL6 transcription repressor)
Chlorocebus sabaeus (green monkey) : BCL6 (BCL6 transcription repressor)
Heterocephalus glaber (naked mole-rat) : Bcl6 (BCL6 transcription repressor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1623,965,052 - 23,988,852 (-)Ensembl
GRCm381623,965,050 - 23,988,866 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371623,965,138 - 23,988,698 (-)NCBIGRCm37mm9NCBIm37
MGSCv361623,880,401 - 23,903,961 (-)NCBImm8
Celera1624,514,447 - 24,538,188 (-)NCBICelera
Cytogenetic Map16 B1NCBI
cM Map1615.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Bcl6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319643
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.