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Gene: Nfkb1 (nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105) Mus musculus
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Symbol: Nfkb1
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
Description: Exhibits RNA polymerase II proximal promoter sequence-specific DNA binding activity; chromatin binding activity; and protein homodimerization activity. Involved in several processes, including cellular response to dsRNA; cellular response to tumor necrosis factor; and regulation of macromolecule biosynthetic process. Localizes to the cytosol and nucleus. Human ortholog(s) of this gene implicated in breast cancer; common variable immunodeficiency; lung non-small cell carcinoma; melanoma; and prostate cancer. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; nose; and respiratory system. Orthologous to human NFKB1 (nuclear factor kappa B subunit 1); PARTICIPATES IN adenosine signaling pathway; ceramide signaling pathway; erythropoietin signaling pathway; INTERACTS WITH (S)-nicotine; 1,4-dithiothreitol; 1-bromopropane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DNA-binding factor KBF1; EBP-1; NF kappaB1; NF-kappa-B1 p84/NF-kappa-B1 p98; NF-kappaB; NF-kappaB p50; NF-kappaB1; NF-KB1; nuclear factor kappaB p50; nuclear factor NF-kappa-B p105 subunit; nuclear factor of kappa light chain gene enhancer in B-cells 1, p105; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105; nuclear factor-kappaB p50; p105; p50; p50 subunit of NF kappaB; p50 subunit of NF-kappaB; p50/p105
Orthologs:
Homo sapiens (human) : NFKB1 (nuclear factor kappa B subunit 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nfkb1 (nuclear factor kappa B subunit 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfkb1 (nuclear factor kappa B subunit 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NFKB1 (nuclear factor kappa B subunit 1)
Canis lupus familiaris (dog) : NFKB1 (nuclear factor kappa B subunit 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfkb1 (nuclear factor kappa B subunit 1)
Sus scrofa (pig) : NFKB1 (nuclear factor kappa B subunit 1)
Chlorocebus sabaeus (African green monkey) : NFKB1 (nuclear factor kappa B subunit 1)
Heterocephalus glaber (naked mole-rat) : Nfkb1 (nuclear factor kappa B subunit 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl3135,584,655 - 135,691,547 (-)Ensembl
GRCm383135,584,655 - 135,691,969 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373135,247,619 - 135,354,511 (-)NCBIGRCm37mm9NCBIm37
MGSCv363135,522,085 - 135,628,727 (-)NCBImm8
Celera3142,004,849 - 142,111,759 (-)NCBICelera
Cytogenetic Map3G3NCBI
cM Map362.82NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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