Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Ggct (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of GGCT mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of GGCT mRNA | CTD | PMID:36331819 | (S)-nicotine | increases splicing | ISO | GGCT (Homo sapiens) | 6480464 | Nicotine results in increased splicing of GGCT mRNA alternative form | CTD | PMID:23825647 | 1,1-dichloroethene | decreases expression | EXP | | 6480464 | vinylidene chloride results in decreased expression of GGCT mRNA | CTD | PMID:26682919 | 1,2-dichloroethane | increases expression | EXP | | 6480464 | ethylene dichloride results in increased expression of GGCT mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of GGCT mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of GGCT mRNA | CTD | PMID:17555576 | 17beta-estradiol | decreases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Estradiol results in decreased expression of GGCT mRNA | CTD | PMID:35192832 | 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one | decreases expression | ISO | GGCT (Homo sapiens) | 6480464 | Metribolone results in decreased expression of GGCT protein | CTD | PMID:17152098 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with 2 more ... | CTD | PMID:28433925 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of GGCT mRNA | CTD | PMID:26377647 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of GGCT mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GGCT mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with 2 more ... | CTD | PMID:28433925 | 3-chloropropane-1,2-diol | decreases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | alpha-Chlorohydrin results in decreased expression of GGCT mRNA | CTD | PMID:28522335 | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of GGCT mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | increases expression | ISO | GGCT (Homo sapiens) | 6480464 | bisphenol S results in increased expression of GGCT protein | CTD | PMID:34186270 | 6-propyl-2-thiouracil | decreases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of GGCT mRNA | CTD | PMID:24780913 | acetamide | decreases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | acetamide results in decreased expression of GGCT mRNA | CTD | PMID:31881176 | acrylamide | decreases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Acrylamide results in decreased expression of GGCT mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Aflatoxin B1 results in increased expression of GGCT mRNA | CTD | PMID:33354967 | all-trans-retinoic acid | decreases expression | ISO | GGCT (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of GGCT mRNA | CTD | PMID:33167477 | arsane | multiple interactions | ISO | GGCT (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of GGCT mRNA | CTD | PMID:32525701 | arsenic atom | multiple interactions | ISO | GGCT (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of GGCT mRNA | CTD | PMID:32525701 | arsenite(3-) | multiple interactions | ISO | GGCT (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to GGCT mRNA] | CTD | PMID:32406909 | benzatropine | multiple interactions | ISO | GGCT (Homo sapiens) | 6480464 | [Cuprizone co-treated with Benztropine] results in decreased expression of GGCT protein | CTD | PMID:34122009 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of GGCT mRNA | CTD | PMID:23735875 | benzo[a]pyrene | increases methylation | ISO | GGCT (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of GGCT promoter | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with 2 more ... | CTD | PMID:28433925 | bis(2-ethylhexyl) phthalate | increases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Diethylhexyl Phthalate results in increased expression of GGCT mRNA | CTD | PMID:36005737 | bisphenol A | affects expression | ISO | Ggct (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of GGCT mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of GGCT mRNA | CTD | PMID:30816183 more ... | bisphenol A | decreases expression | ISO | GGCT (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of GGCT mRNA and bisphenol A results in decreased expression of GGCT protein | CTD | PMID:29275510 more ... | bisphenol A | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with 2 more ... | CTD | PMID:28433925 | Bisphenol B | increases expression | ISO | GGCT (Homo sapiens) | 6480464 | bisphenol B results in increased expression of GGCT protein | CTD | PMID:34186270 | bisphenol F | increases expression | ISO | GGCT (Homo sapiens) | 6480464 | bisphenol F results in increased expression of GGCT protein | CTD | PMID:34186270 | cadmium dichloride | increases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Cadmium Chloride results in increased expression of GGCT mRNA | CTD | PMID:33453195 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in decreased expression of GGCT mRNA | CTD | PMID:25620056 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chromium(6+) | affects expression | EXP | | 6480464 | chromium hexavalent ion affects the expression of GGCT mRNA | CTD | PMID:28472532 | cisplatin | increases expression | ISO | GGCT (Homo sapiens) | 6480464 | Cisplatin results in increased expression of GGCT mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | GGCT (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of GGCT mRNA | CTD | PMID:27392435 | cobalt dichloride | increases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | cobaltous chloride results in increased expression of GGCT mRNA | CTD | PMID:24386269 | copper atom | multiple interactions | ISO | GGCT (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of GGCT mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | GGCT (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of GGCT mRNA | CTD | PMID:20971185 | coumestrol | multiple interactions | ISO | GGCT (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GGCT mRNA | CTD | PMID:19167446 | Cuprizon | multiple interactions | ISO | GGCT (Homo sapiens) | 6480464 | [Cuprizone co-treated with Benztropine] results in decreased expression of GGCT protein | CTD | PMID:34122009 | cyclosporin A | affects expression | ISO | GGCT (Homo sapiens) | 6480464 | Cyclosporine affects the expression of GGCT mRNA | CTD | PMID:25562108 | dextran sulfate | multiple interactions | EXP | | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GGCT mRNA | CTD | PMID:29950665 | dicrotophos | decreases expression | ISO | GGCT (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of GGCT mRNA | CTD | PMID:28302478 | dioxygen | multiple interactions | EXP | | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of GGCT mRNA | CTD | PMID:30529165 | diquat | decreases expression | EXP | | 6480464 | Diquat results in decreased expression of GGCT mRNA | CTD | PMID:36851058 | diuron | decreases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Diuron results in decreased expression of GGCT mRNA | CTD | PMID:21551480 | endosulfan | increases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of GGCT mRNA | CTD | PMID:29391264 | Enterolactone | multiple interactions | ISO | GGCT (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GGCT mRNA | CTD | PMID:19167446 | ethyl methanesulfonate | increases expression | ISO | GGCT (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of GGCT mRNA | CTD | PMID:23649840 | fipronil | increases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | fipronil results in increased expression of GGCT mRNA | CTD | PMID:23962444 | flutamide | increases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of GGCT mRNA | CTD | PMID:24136188 | furan | decreases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | furan results in decreased expression of GGCT mRNA | CTD | PMID:25539665 | gentamycin | increases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of GGCT mRNA | CTD | PMID:33387578 | glafenine | increases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Glafenine results in increased expression of GGCT mRNA | CTD | PMID:24136188 | ivermectin | decreases expression | ISO | GGCT (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of GGCT protein | CTD | PMID:32959892 | lead diacetate | increases expression | EXP | | 6480464 | lead acetate results in increased expression of GGCT mRNA | CTD | PMID:22609695 | methyl methanesulfonate | increases expression | ISO | GGCT (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of GGCT mRNA | CTD | PMID:23649840 | miconazole | increases expression | EXP | | 6480464 | Miconazole results in increased expression of GGCT mRNA | CTD | PMID:27462272 | N-nitrosomorpholine | decreases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | N-nitrosomorpholine results in decreased expression of GGCT protein | CTD | PMID:19716841 | nicotine | increases splicing | ISO | GGCT (Homo sapiens) | 6480464 | Nicotine results in increased splicing of GGCT mRNA alternative form | CTD | PMID:23825647 | nimesulide | increases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | nimesulide results in increased expression of GGCT mRNA | CTD | PMID:24136188 | paracetamol | decreases expression | ISO | GGCT (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of GGCT mRNA | CTD | PMID:26690555 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of GGCT mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of GGCT mRNA | CTD | PMID:36331819 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of GGCT mRNA | CTD | PMID:23091169 | PhIP | decreases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in decreased expression of GGCT mRNA | CTD | PMID:33945839 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of GGCT mRNA | CTD | PMID:20813756 and PMID:23811191 | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of GGCT mRNA | CTD | PMID:23186747 | rotenone | decreases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Rotenone results in decreased expression of GGCT mRNA | CTD | PMID:28374803 | sodium arsenate | multiple interactions | ISO | GGCT (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of GGCT mRNA | CTD | PMID:32525701 | sodium arsenite | decreases expression | ISO | GGCT (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of GGCT mRNA | CTD | PMID:37956786 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of GGCT mRNA | CTD | PMID:37682722 | sunitinib | decreases expression | ISO | GGCT (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of GGCT mRNA | CTD | PMID:31533062 | tamoxifen | increases expression | EXP | | 6480464 | Tamoxifen results in increased expression of GGCT mRNA | CTD | PMID:25123088 | tamoxifen | affects expression | EXP | | 6480464 | Tamoxifen affects the expression of GGCT mRNA | CTD | PMID:17555576 and PMID:20937368 | temozolomide | increases expression | ISO | GGCT (Homo sapiens) | 6480464 | Temozolomide results in increased expression of GGCT mRNA | CTD | PMID:31758290 | tetrachloroethene | decreases expression | EXP | | 6480464 | Tetrachloroethylene results in decreased expression of GGCT mRNA | CTD | PMID:28973375 | tetrachloromethane | multiple interactions | ISO | Ggct (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of GGCT mRNA] | CTD | PMID:31150632 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of GGCT mRNA | CTD | PMID:31919559 | tetrachloromethane | increases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased expression of GGCT mRNA | CTD | PMID:31150632 | thapsigargin | decreases expression | EXP | | 6480464 | Thapsigargin results in decreased expression of GGCT protein | CTD | PMID:24648495 | thioacetamide | decreases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of GGCT mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of GGCT mRNA | CTD | PMID:29264374 | titanium dioxide | multiple interactions | EXP | | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GGCT mRNA | CTD | PMID:29950665 | topotecan | increases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Topotecan results in increased expression of GGCT mRNA | CTD | PMID:25729387 | trichloroethene | increases expression | ISO | Ggct (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of GGCT mRNA | CTD | PMID:33387578 | valproic acid | increases expression | ISO | GGCT (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of GGCT mRNA | CTD | PMID:24383497 and PMID:29154799 | valproic acid | affects expression | ISO | GGCT (Homo sapiens) | 6480464 | Valproic Acid affects the expression of GGCT mRNA | CTD | PMID:25979313 | vincaleukoblastine | affects response to substance | ISO | GGCT (Homo sapiens) | 6480464 | GGCT protein affects the susceptibility to Vinblastine | CTD | PMID:16217747 | |