Calm2 (calmodulin 2) - Rat Genome Database

Name: Calm2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Calm2 (calmodulin 2) Mus musculus

Analyze

Symbol:

Calm2

Name:

calmodulin 2

RGD ID:

10278

MGI Page

MGI

Description:

Is expressed in several structures, including alimentary system; metanephros; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in long QT syndrome 15. Orthologous to human CALM2 (calmodulin 2); PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; calcium/calcium-mediated signaling pathway; calcium/calmodulin dependent kinase 2 signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; Aroclor 1254.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

1500001E21Rik; AL024017; Calm1; Calm3; calmodulin; calmodulin-2; caM; Cam2; CamC

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CALM2 (calmodulin 2)	HGNC	HGNC, NCBI, OrthoDB, Treefam
Rattus norvegicus (Norway rat):	Calm2 (calmodulin 2)	HGNC	NCBI
Chinchilla lanigera (long-tailed chinchilla):	Calm2 (calmodulin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CALM2 (calmodulin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CALM2 (calmodulin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Calm2 (calmodulin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CALM2 (calmodulin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	CALM2 (calmodulin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Calm2 (calmodulin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CALM3 (calmodulin 3)	HGNC	OMA, OrthoDB, OrthoMCL
Homo sapiens (human):	CALM1 (calmodulin 1)	HGNC	OMA, OrthoDB
Alliance orthologs ³
Homo sapiens (human):	CALM2 (calmodulin 2)	Alliance	DIOPT (HGNC\|TreeFam)

Related Pseudogenes:

Gm14480 Gm3010 Gm5881 Gm7039 Gm7308 Gm7743

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	87,740,829 - 87,754,363 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	17	87,740,840 - 87,754,363 (-)	Ensembl
GRCm38	17	87,433,401 - 87,446,935 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	100,199,435 - 100,209,814 (+)	Ensembl	GRCm38		mm10	GRCm38
GRCm38.p6 Ensembl	17	87,433,412 - 87,446,935 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	87,832,741 - 87,846,275 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	17	87,341,743 - 87,355,168 (-)	NCBI			mm8
Celera	17	91,831,455 - 91,844,939 (-)	NCBI		Celera
Cytogenetic Map	17	E4	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cannabis abuse (ISO)

Cocaine-Related Disorders (ISO)

COVID-19 (ISO)

genetic disease (ISO)

long QT syndrome 1 (ISO)

long QT syndrome 15 (ISO)

major depressive disorder (ISO)

phencyclidine abuse (ISO)

Romano-Ward Syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

2,6-dinitrotoluene (ISO)

3,3'-diindolylmethane (ISO)

acrolein (ISO)

aflatoxin B1 (ISO)

aflatoxin M1 (ISO)

aldehydo-D-glucose (ISO)

alpha-pinene (ISO)

ammonium chloride (ISO)

amphetamine (ISO)

antirheumatic drug (ISO)

Aroclor 1254 (EXP)

arsenite(3-) (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (ISO)

buspirone (ISO)

butan-1-ol (ISO)

cerium trichloride (EXP)

chlordecone (EXP)

chloropicrin (ISO)

cisplatin (ISO)

clofibric acid (ISO)

clozapine (ISO)

cocaine (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

D-glucose (ISO)

dicrotophos (ISO)

dieldrin (ISO)

dimethylarsinic acid (ISO)

dioxygen (ISO)

diuron (ISO)

ethanol (EXP,ISO)

folic acid (EXP)

fumonisin B1 (EXP)

gentamycin (ISO)

glucose (ISO)

glyphosate (ISO)

haloperidol (ISO)

hydrogen peroxide (ISO)

maneb (EXP)

methotrexate (ISO)

methylparaben (ISO)

microcystin-LR (EXP)

mifepristone (EXP)

N-nitrosodiethylamine (ISO)

nefazodone (ISO)

nickel dichloride (ISO)

nimesulide (ISO)

nitroglycerin (ISO)

okadaic acid (ISO)

ozone (ISO)

paraquat (EXP)

perfluorooctane-1-sulfonic acid (ISO)

phencyclidine (ISO)

phenobarbital (ISO)

phenytoin (ISO)

progesterone (EXP)

risperidone (ISO)

rotenone (ISO)

sodium fluoride (EXP)

Tributyltin oxide (EXP)

trichloroethene (ISO)

tunicamycin (ISO)

uranium atom (ISO)

valproic acid (ISO)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

activation of adenylate cyclase activity (ISO)

autophagosome membrane docking (ISO)

calcium-mediated signaling (ISO)

detection of calcium ion (ISO)

establishment of protein localization to membrane (ISO)

establishment of protein localization to mitochondrial membrane (ISO)

G2/M transition of mitotic cell cycle (IDA)

mitochondrion-endoplasmic reticulum membrane tethering (ISO)

negative regulation of high voltage-gated calcium channel activity (ISO)

negative regulation of ryanodine-sensitive calcium-release channel activity (ISO)

organelle localization by membrane tethering (ISO)

positive regulation of cyclic-nucleotide phosphodiesterase activity (ISO)

positive regulation of nitric-oxide synthase activity (ISO)

positive regulation of phosphoprotein phosphatase activity (ISO)

positive regulation of protein dephosphorylation (ISO)

positive regulation of ryanodine-sensitive calcium-release channel activity (ISO)

regulation of cardiac muscle cell action potential (ISO)

regulation of cardiac muscle contraction (ISO)

regulation of cytokinesis (ISO)

regulation of heart rate (ISO)

regulation of high voltage-gated calcium channel activity (ISO)

regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (ISO)

regulation of ryanodine-sensitive calcium-release channel activity (IBA,ISO)

regulation of synaptic vesicle endocytosis (ISO)

regulation of synaptic vesicle exocytosis (ISO)

response to amphetamine (ISO)

response to calcium ion (ISO)

response to corticosterone (ISO)

substantia nigra development (ISO)

Cellular Component

calcium channel complex (ISO)

catalytic complex (ISO)

centrosome (ISO)

cytoplasm (ISO)

growth cone (ISO)

mitochondrial membrane (ISO)

myelin sheath (IDA,ISO)

neuron projection (ISO)

nucleus (ISO)

plasma membrane (ISO)

protein-containing complex (ISO)

sarcomere (ISO)

spindle microtubule (ISO)

spindle pole (ISO)

synaptic vesicle membrane (ISO)

voltage-gated potassium channel complex (IGI)

Molecular Function

adenylate cyclase activator activity (ISO)

adenylate cyclase binding (ISO)

calcium channel inhibitor activity (ISO)

calcium ion binding (IBA,ISO,TAS)

calcium-dependent protein binding (ISO)

disordered domain specific binding (ISO)

enzyme regulator activity (IBA)

ion channel binding (ISO)

N-terminal myristoylation domain binding (ISO)

nitric-oxide synthase binding (ISO)

nitric-oxide synthase regulator activity (ISO)

phosphatidylinositol 3-kinase binding (ISO)

protein binding (ISO)

protein domain specific binding (ISO)

protein kinase binding (ISO)

protein N-terminus binding (ISO)

protein phosphatase activator activity (ISO)

titin binding (ISO)

type 3 metabotropic glutamate receptor binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

adenosine monophosphate-activated protein kinase (AMPK) signaling pathway (ISO)

Alzheimer's disease pathway (IEA)

calcium/calcium-mediated signaling pathway (ISO)

calcium/calmodulin dependent kinase 2 signaling pathway (ISO)

glioma pathway (IEA)

glycogen degradation pathway (ISO)

gonadotropin-releasing hormone signaling pathway (IEA)

insulin responsive facilitative sugar transporter mediated glucose transport pathway (ISO)

insulin signaling pathway (IEA)

long term potentiation (IEA)

N-cadherin signaling pathway (ISO)

neurotrophic factor signaling pathway (IEA)

p38 MAPK signaling pathway (ISO)

phosphatidylinositol 3-kinase signaling pathway (IEA)

tuberculosis pathway (IEA)

type II interferon signaling pathway (ISO)

vascular endothelial growth factor signaling pathway (ISO)

visual phototransduction pathway (IEA)

References

References - curated


1.	Brushia RJ and Walsh DA, Front Biosci. 1999 Sep 15;4:D618-41.
2.	Chin D and Means AR, Trends Cell Biol. 2000 Aug;10(8):322-8.
3.	Clapham DE, Cell. 2007 Dec 14;131(6):1047-58.
4.	Coultrap SJ and Bayer KU, Trends Neurosci. 2012 Oct;35(10):607-18. doi: 10.1016/j.tins.2012.05.003. Epub 2012 Jun 19.
5.	Hawley SA, etal., Cell Metab. 2005 Jul;2(1):9-19.
6.	Kang HJ, etal., Nat Med. 2012 Aug 12. doi: 10.1038/nm.2886.
7.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
8.	MGD and Homologene mouse data transfer
9.	MGD data from the GO Consortium
10.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
11.	Pipeline to import KEGG annotations from KEGG into RGD
12.	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
13.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14.	RGD automated import pipeline for gene-chemical interactions
15.	Rokita AG and Anderson ME, Circulation. 2012 Oct 23;126(17):2125-39. doi: 10.1161/CIRCULATIONAHA.112.124990.

Additional References at PubMed

PMID:2469574	PMID:2551780	PMID:3384819	PMID:7671812	PMID:7828884	PMID:9238065	PMID:10349636	PMID:10922068	PMID:11042159	PMID:11076861	PMID:11172053	PMID:12223552
PMID:12477932	PMID:12520002	PMID:12904583	PMID:14610273	PMID:14681479	PMID:15499021	PMID:15741177	PMID:16141072	PMID:16141073	PMID:16310175	PMID:16458478	PMID:16602821
PMID:18554416	PMID:18799693	PMID:19188439	PMID:19855925	PMID:21565611	PMID:21873635	PMID:22683701	PMID:24165879	PMID:25737280	PMID:29518331	PMID:30409884	PMID:32522888

Genomics

Comparative Map Data

Calm2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	87,740,829 - 87,754,363 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	17	87,740,840 - 87,754,363 (-)	Ensembl
GRCm38	17	87,433,401 - 87,446,935 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	100,199,435 - 100,209,814 (+)	Ensembl	GRCm38		mm10	GRCm38
GRCm38.p6 Ensembl	17	87,433,412 - 87,446,935 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	87,832,741 - 87,846,275 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	17	87,341,743 - 87,355,168 (-)	NCBI			mm8
Celera	17	91,831,455 - 91,844,939 (-)	NCBI		Celera
Cytogenetic Map	17	E4	NCBI

CALM2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	2	47,160,083 - 47,176,921 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	2	47,160,082 - 47,176,936 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	2	47,387,221 - 47,404,075 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	47,240,809 - 47,257,154 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	2	47,298,955 - 47,315,301	NCBI
Celera	2	47,226,054 - 47,242,551 (-)	NCBI
Cytogenetic Map	2	p21	NCBI
HuRef	2	47,124,359 - 47,140,853 (-)	NCBI		HuRef
CHM1_1	2	47,317,465 - 47,334,257 (-)	NCBI		CHM1_1

Calm2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	6	7,091,624 - 7,104,284 (+)	NCBI
Rnor_6.0 Ensembl	15	65,506,874 - 65,507,968 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	6	11,067,675 - 11,080,078 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	6	21,052,945 - 21,068,133 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	64,161,641 - 64,162,751 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	15	64,177,420 - 64,178,531 (-)	NCBI
Celera	6	6,842,934 - 6,855,590 (+)	NCBI		Celera
Cytogenetic Map	6	q12	NCBI

Calm2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955441	13,973,147 - 13,988,665 (-)	NCBI	ChiLan1.0	ChiLan1.0

CALM2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	2A	48,204,518 - 48,220,697 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	48,204,518 - 48,220,697 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	2A	47,274,722 - 47,290,861 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

CALM2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	10	49,299,897 - 49,314,457 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	10	49,299,698 - 49,314,533 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Calm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936508	5,207,909 - 5,223,780 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CALM2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	93,372,045 - 93,438,068 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	93,371,765 - 93,386,378 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	99,567,552 - 99,582,160 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CALM2
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	60,027,884 - 60,042,041 (+)	NCBI
ChlSab1.1 Ensembl	14	60,027,801 - 60,044,951 (+)	Ensembl
ChlSab1.1 Ensembl	24	68,133,428 - 68,145,180 (+)	Ensembl
ChlSab1.1 Ensembl	6	39,957,320 - 39,966,581 (+)	Ensembl

Calm2
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624738	28,525,290 - 28,541,562 (-)	NCBI

Position Markers

WI-9106

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	17	87,433,647 - 87,433,761	UniSTS	GRCm38
MGSCv37	17	87,832,987 - 87,833,101	UniSTS	GRCm37
Celera	17	91,831,701 - 91,831,815	UniSTS
Cytogenetic Map	17	E4	UniSTS

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4141758	Pstc5_m	periosteal circumference 5 (mouse)			Not determined		17	56800656	90800808	Mouse
4141011	Bmd26_m	bone mineral density 26 (mouse)			Not determined		17	56800656	90800808	Mouse
1300735	Pgia20_m	proteoglycan induced arthritis 20 (mouse)			Not determined		17	56800656	90800808	Mouse
1357447	Heal13_m	wound healing/regeneration 13 (mouse)			Not determined		17	56800656	90800808	Mouse
12910536	Nrq8a_m	noise-induced hearing loss resistant QTL 8a (mouse)					17	56800656	90800808	Mouse
12910537	Nrq8_m	noise-induced hearing loss resistant QTL 8 (mouse)					17	56800656	90800808	Mouse
4142414	Pregq4_m	pregnancy QTL 4 (mouse)			Not determined		17	57227447	93199751	Mouse
4141040	Hmtb9_m	hemostasis and thrombosis rebleeding time 9 (mouse)			Not determined			57282094	91282202	Mouse
1301107	Scc4_m	colon tumor susceptibility 4 (mouse)			Not determined		17	61993581	94987271	Mouse
11528551	Sluc32_m	susceptibility to lung cancer 32 (mouse)					17	61993581	94987271	Mouse
1302017	Aliq3_m	acute lung injury QTL 3 (mouse)			Not determined		17	63578119	94987271	Mouse
1301728	Ffal1_m	free fatty acid level 1 (mouse)			Not determined		17	64907509	94987271	Mouse
14928308	Manh82_m	mandible shape 82 (mouse)					17	66007814	94987271	Mouse
4142256	Nilac12_m	nicotine induced locomotor activity 12 (mouse)			Not determined		17	68633891	94987271	Mouse
11039498	Ltpr7b_m	Leishmania tropica response 7b (mouse)					17	70393770	94987271	Mouse
11039499	Ltpr7a_m	Leishmania tropica response 7a (mouse)					17	70393770	94987271	Mouse
11039500	Ltpr7c_m	Leishmania tropica response 7c (mouse)					17	70393770	94987271	Mouse
11039514	Ltpr7_m	Leishmania tropica response 7 (mouse)					17	70393770	94987271	Mouse
1357528	Nhdlq3_m	non-HDL QTL 3 (mouse)			Not determined		17	73087704	94987271	Mouse
4141195	Nilac11_m	nicotine induced locomotor activity 11 (mouse)			Not determined		17	73087704	94987271	Mouse
4141697	Hbnr3_m	Heligmosomoides bakeri nematode resistance 3 (mouse)			Not determined			73800656	93199751	Mouse
1357552	Aaj4_m	anxiety in A/J 4 (mouse)			Not determined		17	74282094	90087842	Mouse
1357646	Axtq3_m	anxiety QTL 3 (mouse)			Not determined		17	74282094	90087842	Mouse
14697708	Stsl5_m	Salmonella typhimurium susceptibility locus 5 (mouse)					17	80500000	91100000	Mouse

miRNA Target Status

Confirmed Target Of

miRNA Gene	Mature miRNA	Method Name	Result Type	Data Type	Support Type	PMID
Mir1a-1	mmu-miR-1a-3p	Mirtarbase	external_info	qRT-PCR//Western blot//Luciferase reporter assay	Functional MTI	19188439
Mir1a-2	mmu-miR-1a-3p	Mirtarbase	external_info	qRT-PCR//Western blot//Luciferase reporter assay	Functional MTI	19188439

Predicted Target Of

	Summary Value
Count of predictions:	246
Count of miRNA genes:	192
Interacting mature miRNAs:	200
Transcripts:	ENSMUST00000040440, ENSMUST00000143965, ENSMUST00000150137
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001355703	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_007589	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC084383	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK002974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK005089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK012247	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK012564	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK013068	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK152303	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK160636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK161268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK161984	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK168741	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK169591	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY902353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC010730	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC021347	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC051444	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC100301	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BY095488	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BY660536	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BY663775	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CX565080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D12623	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L31642	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M27844	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000040440 ⟹ ENSMUSP00000048857

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	17	87,433,412 - 87,446,935 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000143965

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	17	87,433,720 - 87,446,848 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000150137

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	17	87,434,894 - 87,446,849 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000234406 ⟹ ENSMUSP00000157025

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	17	87,433,665 - 87,446,856 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000238271 ⟹ ENSMUSP00000158587

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	17	87,435,626 - 87,446,935 (-)	Ensembl

RefSeq Acc Id:

NM_001355703 ⟹ NP_001342632

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	17	87,740,829 - 87,754,363 (-)	NCBI
GRCm38	17	87,433,401 - 87,446,935 (-)	NCBI

Sequence:

show sequence

GAGGCGGAGGGATCTGGCGGAGGGAGGCGGAGGGAGGTGTTTATGAGGAGCTGGGGGCGGAGGA
GGAGAATTAGTCCGAGTGGAGCGAGCGAGTCGAGCGGTTGTCTGGTCGCGTCTCGGAAACCCGT
AGCCCTTGCAGCATGAGTTCAAAGAAGCTTTCTCACTATTTGACAAGGACGGGGATGGGACAAT
AACAACAAAGGAGCTGGGGACAGTGATGAGGTCCCTGGGGCAGAACCCCACAGAAGCAGAACTG
CAGGACATGATCAATGAAGTAGATGCGGATGGTAATGGCACAATTGATTTCCCTGAATTTCTGA
CAATGATGGCAAGAAAAATGAAAGACACAGACAGTGAAGAAGAGATTAGAGAAGCATTCCGTGT
GTTTGATAAGGATGGCAATGGCTATATTAGTGCAGCAGAGCTTCGCCATGTGATGACAAACCTT
GGCGAGAAGTTAACAGATGAAGAGGTCGATGAGATGATCAGGGAAGCAGACATTGACGGGGACG
GTCAGGTAAACTACGAAGAGTTTGTACAAATGATGACAGCGAAGTGAAGACATTGTACAGAATG
TGTTAAATTTCTTGTACAAAATTGTTTATTTGCCTTTTCTTTGTTTGTAACTTATCTGTAAAAG
GTTCCCCCCCCCTACTGTCAAAAAATATGCATGTATAGTAATTAGGACTTCATTCCTCCATGTT
TTCTTCCCTTATCTTACTGTCATTGTCCTTAAACCTTATTTTAGAAAATTGATGAAGTAACATG
TTGCATGTGGCTTACTCTGGCTATATCTAAGCCCGTCTGCACATCTAAACTTAGATGGAGTTGG
TCCAATGAGGGAACATCTGGGTTATGCCTTTTTTAAAGTAGCTTTTAGGAACTGTCAGCATGTT
GTTGTTGAAGTGTGGAGCTGTAACTCTGCGTGGACTGTGGACAGTCAACAATATGTACTTAAAA
GTTGCACTATTGCAAAACGGGTGTTTTATCCAGGTACTCGGACACTATTTTTTTGTACTGCTGG
TATTGTACCAGGAACATTTTCTTTTATTGTTACTTGCTTTTTAAACTTTGTTTAGCCACTTAAA
GAAAACCTGCTCATGGCACAACTTGCCTCAAATCCATTCCAAGTTGTATATTTGTTTTCCAATA
AAAAAAATTACAATTTACCCAATTGTTGCTCTG

hide sequence

RefSeq Acc Id:

NM_007589 ⟹ NP_031615

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	17	87,740,829 - 87,754,363 (-)	NCBI
GRCm38	17	87,433,401 - 87,446,935 (-)	ENTREZGENE
MGSCv37	17	87,832,741 - 87,846,275 (-)	RGD
Celera	17	91,831,455 - 91,844,939 (-)	RGD
cM Map	17		ENTREZGENE

Sequence:

show sequence

GAGGCGGAGGGATCTGGCGGAGGGAGGCGGAGGGAGGTGTTTATGAGGAGCTGGGGGCGGAGGA
GGAGAATTAGTCCGAGTGGAGCGAGCGAGTCGAGCGGTTGTCTGGTCGCGTCTCGGAAACCCGT
AGCCCTTGCAGCATGGCTGACCAACTGACTGAAGAGCAGATTGCAGAGTTCAAAGAAGCTTTCT
CACTATTTGACAAGGACGGGGATGGGACAATAACAACAAAGGAGCTGGGGACAGTGATGAGGTC
CCTGGGGCAGAACCCCACAGAAGCAGAACTGCAGGACATGATCAATGAAGTAGATGCGGATGGT
AATGGCACAATTGATTTCCCTGAATTTCTGACAATGATGGCAAGAAAAATGAAAGACACAGACA
GTGAAGAAGAGATTAGAGAAGCATTCCGTGTGTTTGATAAGGATGGCAATGGCTATATTAGTGC
AGCAGAGCTTCGCCATGTGATGACAAACCTTGGCGAGAAGTTAACAGATGAAGAGGTCGATGAG
ATGATCAGGGAAGCAGACATTGACGGGGACGGTCAGGTAAACTACGAAGAGTTTGTACAAATGA
TGACAGCGAAGTGAAGACATTGTACAGAATGTGTTAAATTTCTTGTACAAAATTGTTTATTTGC
CTTTTCTTTGTTTGTAACTTATCTGTAAAAGGTTCCCCCCCCCTACTGTCAAAAAATATGCATG
TATAGTAATTAGGACTTCATTCCTCCATGTTTTCTTCCCTTATCTTACTGTCATTGTCCTTAAA
CCTTATTTTAGAAAATTGATGAAGTAACATGTTGCATGTGGCTTACTCTGGCTATATCTAAGCC
CGTCTGCACATCTAAACTTAGATGGAGTTGGTCCAATGAGGGAACATCTGGGTTATGCCTTTTT
TAAAGTAGCTTTTAGGAACTGTCAGCATGTTGTTGTTGAAGTGTGGAGCTGTAACTCTGCGTGG
ACTGTGGACAGTCAACAATATGTACTTAAAAGTTGCACTATTGCAAAACGGGTGTTTTATCCAG
GTACTCGGACACTATTTTTTTGTACTGCTGGTATTGTACCAGGAACATTTTCTTTTATTGTTAC
TTGCTTTTTAAACTTTGTTTAGCCACTTAAAGAAAACCTGCTCATGGCACAACTTGCCTCAAAT
CCATTCCAAGTTGTATATTTGTTTTCCAATAAAAAAAATTACAATTTACCCAATTGTTGCTCTG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001342632	(Get FASTA)	NCBI Sequence Viewer
	NP_031615	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA37365	(Get FASTA)	NCBI Sequence Viewer
	AAA65934	(Get FASTA)	NCBI Sequence Viewer
	AAH10730	(Get FASTA)	NCBI Sequence Viewer
	AAH21347	(Get FASTA)	NCBI Sequence Viewer
	AAH51444	(Get FASTA)	NCBI Sequence Viewer
	AAI00302	(Get FASTA)	NCBI Sequence Viewer
	AAY21063	(Get FASTA)	NCBI Sequence Viewer
	BAA02147	(Get FASTA)	NCBI Sequence Viewer
	BAB28116	(Get FASTA)	NCBI Sequence Viewer
	BAB28319	(Get FASTA)	NCBI Sequence Viewer
	BAB28631	(Get FASTA)	NCBI Sequence Viewer
	BAE31109	(Get FASTA)	NCBI Sequence Viewer
	BAE35930	(Get FASTA)	NCBI Sequence Viewer
	BAE36280	(Get FASTA)	NCBI Sequence Viewer
	BAE36667	(Get FASTA)	NCBI Sequence Viewer
	BAE40582	(Get FASTA)	NCBI Sequence Viewer
	P0DP27	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_031615 ⟸ NM_007589
- Peptide Label:	isoform 1
- UniProtKB:	P0DP28 (UniProtKB/Swiss-Prot), P0DP27 (UniProtKB/Swiss-Prot), P0DP26 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI DFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIRE ADIDGDGQVNYEEFVQMMTAK hide sequence

RefSeq Acc Id:	NP_001342632 ⟸ NM_001355703
- Peptide Label:	isoform 2

RefSeq Acc Id:

ENSMUSP00000048857 ⟸ ENSMUST00000040440

RefSeq Acc Id:

ENSMUSP00000158587 ⟸ ENSMUST00000238271

RefSeq Acc Id:

ENSMUSP00000157025 ⟸ ENSMUST00000234406

Protein Domains

EF-hand

Promoters

RGD ID:

13676954

Promoter ID:

EPDNEW_M22626

Type:

initiation region

Name:

Calm2_1

Description:

Mus musculus calmodulin 2 , transcript variant 1, mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	17	87,446,863 - 87,446,923	EPDNEW

RGD ID:

6827903

Promoter ID:

MM_KWN:24401

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

NM_007589, OTTMUST00000054018, OTTMUST00000054019

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	17	87,846,126 - 87,846,707 (-)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:103250	AgrOrtholog
Ensembl Genes	ENSMUSG00000001175	Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSMUSG00000019370	UniProtKB/Swiss-Prot
	ENSMUSG00000036438	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000001204	UniProtKB/TrEMBL
	ENSMUSP00000019514	UniProtKB/Swiss-Prot
	ENSMUSP00000048857	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUSP00000105709	UniProtKB/Swiss-Prot
	ENSMUSP00000157025	ENTREZGENE, UniProtKB/TrEMBL
	ENSMUSP00000158587	UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000001204	UniProtKB/TrEMBL
	ENSMUST00000019514	UniProtKB/Swiss-Prot
	ENSMUST00000040440	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUST00000110082	UniProtKB/Swiss-Prot
	ENSMUST00000234406	ENTREZGENE, UniProtKB/TrEMBL
	ENSMUST00000238271	UniProtKB/TrEMBL
InterPro	EF-hand-dom_pair	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EF_hand_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:12313	UniProtKB/Swiss-Prot
	mmu:12314	UniProtKB/Swiss-Prot
	mmu:12315	UniProtKB/Swiss-Prot
MGD	MGI:103250	ENTREZGENE
NCBI Gene	12314	ENTREZGENE
Pfam	EF-hand_1	UniProtKB/TrEMBL
	EF-hand_7	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Calm2	PhenoGen
PROSITE	EF_HAND_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	EFh	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF47473	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A3Q4EHJ0_MOUSE	UniProtKB/TrEMBL
	A0A571BE58_MOUSE	UniProtKB/TrEMBL
	CALM1_MOUSE	UniProtKB/Swiss-Prot
	CALM2_MOUSE	UniProtKB/Swiss-Prot
	CALM3_MOUSE	UniProtKB/Swiss-Prot
	P0DP26	ENTREZGENE
	P0DP27	ENTREZGENE
	P0DP28	ENTREZGENE
UniProt Secondary	P02593	UniProtKB/Swiss-Prot
	P62204	UniProtKB/Swiss-Prot
	P70667	UniProtKB/Swiss-Prot
	P99014	UniProtKB/Swiss-Prot
	Q3TEH7	UniProtKB/Swiss-Prot
	Q3THK5	UniProtKB/Swiss-Prot
	Q3U6Z5	UniProtKB/Swiss-Prot
	Q3U7C7	UniProtKB/Swiss-Prot
	Q498A3	UniProtKB/Swiss-Prot
	Q61379	UniProtKB/Swiss-Prot
	Q61380	UniProtKB/Swiss-Prot
	Q8BNC9	UniProtKB/Swiss-Prot
	Q91VQ9	UniProtKB/Swiss-Prot
	Q9D6G4	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)