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Gene: Gad1 (glutamate decarboxylase 1) Mus musculus
Symbol: Gad1
Name: glutamate decarboxylase 1
Description: Predicted to have several functions, including anion binding activity; glutamate decarboxylase activity; and protein heterodimerization activity. Involved in locomotory exploration behavior and social behavior. Localizes to several cellular components, including the axon terminus; inhibitory synapse; and presynaptic active zone. Human ortholog(s) of this gene implicated in anxiety disorder; bipolar disorder; schizophrenia; and spastic quadriplegia. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb bud; and sensory organ. Orthologous to human GAD1 (glutamate decarboxylase 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 67 kDa glutamic acid decarboxylase; EP10; Gad-1; GAD-67; GAD25; GAD44; GAD67; glutamate decarboxylase 67 kDa isoform; GLUTAMATE DECARBOXYLASE, 67 KD ISOFORM (GAD-67) (67 KD GLUTAMIC ACID DECARBOXYLASE); glutamic acid decarboxylase 1
Homo sapiens (human) : GAD1 (glutamate decarboxylase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gad1 (glutamate decarboxylase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gad1 (glutamate decarboxylase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GAD1 (glutamate decarboxylase 1)
Canis lupus familiaris (dog) : GAD1 (glutamate decarboxylase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gad1 (glutamate decarboxylase 1)
Sus scrofa (pig) : GAD1 (glutamate decarboxylase 1)
Chlorocebus sabaeus (green monkey) : GAD1 (glutamate decarboxylase 1)
Heterocephalus glaber (naked mole-rat) : Gad1 (glutamate decarboxylase 1)
more info ...
Related Pseudogenes: Gad1-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl270,553,072 - 70,602,014 (+)Ensembl
GRCm38270,561,303 - 70,602,014 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37270,400,221 - 70,440,069 (+)NCBIGRCm37mm9NCBIm37
MGSCv36270,363,052 - 70,402,853 (+)NCBImm8
Celera272,228,088 - 72,268,083 (+)NCBICelera
Cytogenetic Map2C2NCBI
cM Map241.63NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Gad1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10615
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.