Lgals1 (lectin, galactose binding, soluble 1) - Rat Genome Database

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Gene: Lgals1 (lectin, galactose binding, soluble 1) Mus musculus
Analyze
Symbol: Lgals1
Name: lectin, galactose binding, soluble 1
RGD ID: 737568
MGI Page MGI
Description: Enables carbohydrate binding activity. Acts upstream of or within T cell costimulation; myoblast differentiation; and plasma cell differentiation. Located in extracellular space. Is expressed in several structures, including cardiovascular system; embryo mesenchyme; genitourinary system; main olfactory bulb; and olfactory system. Orthologous to human LGALS1 (galectin 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 14 kDa lectin; AA410090; beta-galactoside binding protein; beta-galactoside-binding lectin L-14-I; Ga; Gal; Gal-1; galaptin; Galbp; galect; galectin-1; L-14.5; L1; L14; lactose-binding lectin 1; Lect1; Lect14; lectin galactoside-binding soluble 1; S-Lac lectin 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Lgals1-ps2  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391578,810,925 - 78,814,665 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1578,810,925 - 78,814,665 (+)EnsemblGRCm39 Ensembl
GRCm381578,926,725 - 78,930,465 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1578,926,725 - 78,930,465 (+)EnsemblGRCm38mm10GRCm38
MGSCv371578,757,155 - 78,760,895 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361578,753,980 - 78,757,720 (+)NCBIMGSCv36mm8
MGSCv361579,650,845 - 79,654,585 (+)NCBIMGSCv36mm8
Cytogenetic Map15E1NCBI
cM Map1537.7NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (EXP)
(S)-nicotine  (ISO)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-methyladenine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP)
5-aza-2'-deoxycytidine  (ISO)
8-Br-cAMP  (ISO)
acetohydrazide  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (EXP,ISO)
alachlor  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
Ampullosporin  (ISO)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
atrazine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
Benzo[k]fluoranthene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
camptothecin  (ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
choline  (EXP)
chrysene  (ISO)
cisplatin  (EXP,ISO)
clobetasol  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
corn oil  (ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
D-penicillamine  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (EXP,ISO)
diazinon  (EXP)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
dihydroartemisinin  (ISO)
dimethyl sulfoxide  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
fenamidone  (EXP)
fenofibrate  (EXP)
fipronil  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
fructose  (ISO)
fulvestrant  (ISO)
furan  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glycidyl methacrylate  (ISO)
haloperidol  (ISO)
hyaluronic acid  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
ibuprofen  (ISO)
imidazopyrazole  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indole-3-methanol  (ISO)
inulin  (EXP)
iron dichloride  (ISO)
isobutanol  (ISO)
ivermectin  (ISO)
ketamine  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (EXP)
lead(0)  (ISO)
lidocaine  (EXP)
lipopolysaccharide  (EXP)
malathion  (ISO)
microcystin RR  (ISO)
microcystin-LR  (EXP)
N(4)-hydroxycytidine  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
naphthalene  (EXP,ISO)
nickel subsulfide  (ISO)
nicotine  (ISO)
Nutlin-3  (ISO)
ouabain  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
parathion  (EXP)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenanthrene  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP,ISO)
progesterone  (EXP)
quercetin  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sodium fluoride  (EXP)
sulfadimethoxine  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
tamibarotene  (ISO)
tamoxifen  (EXP)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
tetradecane  (ISO)
tetraphene  (ISO)
thapsigargin  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (EXP)
tungsten  (EXP)
valproic acid  (EXP,ISO)
vancomycin  (EXP)
vorinostat  (ISO)
zearalenone  (ISO)
zidovudine  (ISO)
zinc oxide  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Nodal signalling in the epiblast patterns the early mouse embryo. Brennan J, etal., Nature 2001 Jun 21;411(6840):965-9.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Ko MS, etal., Hum Mol Genet 1998 Nov;7(12):1967-78.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Expression of galectin-1, a new component of slit diaphragm, is altered in minimal change nephrotic syndrome. Shimizu M, etal., Lab Invest. 2009 Feb;89(2):178-95. Epub 2008 Dec 15.
11. Factors released from cholestatic rat livers possibly involved in inducing bone marrow hepatic stem cell priming. Xu J, etal., Stem Cells Dev. 2008 Feb;17(1):143-55.
12. Low-dose cyclophosphamide modulates galectin-1 expression and function in an experimental rat lymphoma model. Zacarias Fluck MF, etal., Cancer Immunol Immunother. 2007 Feb;56(2):237-48. Epub 2006 May 30.
Additional References at PubMed
PMID:1627600   PMID:1638977   PMID:1986871   PMID:2025648   PMID:2335567   PMID:2803247   PMID:3020551   PMID:3335026   PMID:8043949   PMID:8306885   PMID:8432540   PMID:8674632  
PMID:8862771   PMID:8873770   PMID:8889548   PMID:9027489   PMID:9171370   PMID:9502734   PMID:9560246   PMID:9566950   PMID:9613594   PMID:9727835   PMID:9931450   PMID:10329612  
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11830565   PMID:11839787   PMID:12194966   PMID:12271131   PMID:12477932   PMID:12853445   PMID:14610273   PMID:15181456  
PMID:15489334   PMID:15579141   PMID:15593120   PMID:15733626   PMID:16141072   PMID:16141073   PMID:16565088   PMID:16602821   PMID:16636291   PMID:16891398   PMID:16951131   PMID:16982907  
PMID:17015713   PMID:17015718   PMID:17043243   PMID:17110462   PMID:17182582   PMID:17366633   PMID:17486104   PMID:17495956   PMID:17589510   PMID:17706016   PMID:18026113   PMID:18155296  
PMID:18287559   PMID:18302939   PMID:18307411   PMID:18323414   PMID:18372340   PMID:18479958   PMID:18554416   PMID:18597104   PMID:18606998   PMID:18799693   PMID:18802059   PMID:18850073  
PMID:18991278   PMID:19008923   PMID:19103599   PMID:19171142   PMID:19266163   PMID:19299701   PMID:19329777   PMID:19334288   PMID:19380775   PMID:19423573   PMID:19668220   PMID:19712265  
PMID:19766118   PMID:19920154   PMID:19941913   PMID:20236931   PMID:20421595   PMID:20647324   PMID:21191065   PMID:21217009   PMID:21228929   PMID:21267068   PMID:21269521   PMID:21356371  
PMID:21385934   PMID:21386911   PMID:21511956   PMID:21523436   PMID:21546572   PMID:21614093   PMID:21670307   PMID:21753146   PMID:21795357   PMID:21873635   PMID:21884595   PMID:21947259  
PMID:22076801   PMID:22158550   PMID:22162045   PMID:22267483   PMID:22291012   PMID:22357632   PMID:22416080   PMID:22456341   PMID:22467659   PMID:22484915   PMID:22622427   PMID:22844466  
PMID:22865279   PMID:22884314   PMID:23027923   PMID:23115194   PMID:23118208   PMID:23142379   PMID:23356407   PMID:23404109   PMID:23423643   PMID:23550149   PMID:23563688   PMID:23616571  
PMID:23720814   PMID:23751344   PMID:23798433   PMID:23954858   PMID:24006456   PMID:24323124   PMID:24457600   PMID:24468067   PMID:24498007   PMID:24529377   PMID:24561343   PMID:24707896  
PMID:24812270   PMID:24928277   PMID:24952961   PMID:24979200   PMID:25007042   PMID:25243744   PMID:25392933   PMID:25468561   PMID:25473847   PMID:25533336   PMID:25597246   PMID:25708191  
PMID:25756799   PMID:26136479   PMID:26216879   PMID:26223819   PMID:26250529   PMID:26261609   PMID:26336360   PMID:26451839   PMID:26566180   PMID:26827730   PMID:26857229   PMID:26876172  
PMID:26878424   PMID:26888257   PMID:27151444   PMID:27166189   PMID:27211330   PMID:27418600   PMID:27457925   PMID:27496330   PMID:28071719   PMID:28257831   PMID:28345074   PMID:28378742  
PMID:28512739   PMID:28535371   PMID:28695960   PMID:28713822   PMID:28716827   PMID:28887481   PMID:29122660   PMID:29215607   PMID:29426942   PMID:29615514   PMID:29891717   PMID:29975570  
PMID:30032146   PMID:30065303   PMID:30120235   PMID:30277820   PMID:30319642   PMID:30365068   PMID:30457570   PMID:30550785   PMID:30897344   PMID:32156558   PMID:32161138   PMID:32325033  
PMID:32682987   PMID:33147994   PMID:33166603   PMID:33181141   PMID:33398185   PMID:33431823   PMID:33483548   PMID:33583770   PMID:33952457   PMID:33973144   PMID:33978732   PMID:34006646  
PMID:34262567   PMID:34321999   PMID:34748271   PMID:34827634   PMID:35012549   PMID:35294231   PMID:35364055   PMID:35773253   PMID:36006656   PMID:36114006   PMID:36404916   PMID:36437381  
PMID:36591221   PMID:36685938   PMID:36921487   PMID:36934391   PMID:37409887   PMID:37557976   PMID:37586772   PMID:37926281   PMID:38011284   PMID:38105757   PMID:38254721   PMID:39106860  


Genomics

Comparative Map Data
Lgals1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391578,810,925 - 78,814,665 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1578,810,925 - 78,814,665 (+)EnsemblGRCm39 Ensembl
GRCm381578,926,725 - 78,930,465 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1578,926,725 - 78,930,465 (+)EnsemblGRCm38mm10GRCm38
MGSCv371578,757,155 - 78,760,895 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361578,753,980 - 78,757,720 (+)NCBIMGSCv36mm8
MGSCv361579,650,845 - 79,654,585 (+)NCBIMGSCv36mm8
Cytogenetic Map15E1NCBI
cM Map1537.7NCBI
LGALS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382237,675,636 - 37,679,802 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2237,675,636 - 37,679,802 (+)EnsemblGRCh38hg38GRCh38
GRCh372238,071,643 - 38,075,809 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,401,559 - 36,405,755 (+)NCBINCBI36Build 36hg18NCBI36
Build 342236,396,142 - 36,400,307NCBI
Celera2221,873,464 - 21,877,660 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2221,038,558 - 21,042,751 (+)NCBIHuRef
CHM1_12238,030,320 - 38,034,516 (+)NCBICHM1_1
T2T-CHM13v2.02238,136,888 - 38,141,054 (+)NCBIT2T-CHM13v2.0
Lgals1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,365,695 - 112,368,801 (+)NCBIGRCr8
mRatBN7.27110,485,239 - 110,488,345 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,481,392 - 110,488,345 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,234,764 - 112,237,858 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,458,284 - 114,461,378 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,426,881 - 114,429,988 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,153,184 - 120,156,290 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,153,184 - 120,156,289 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07120,144,875 - 120,147,981 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47116,893,662 - 116,896,768 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17116,927,891 - 116,930,997 (+)NCBI
Celera7106,819,373 - 106,822,479 (+)NCBICelera
Cytogenetic Map7q34NCBI
Lgals1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541324,072,086 - 24,075,452 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541324,072,086 - 24,075,452 (+)NCBIChiLan1.0ChiLan1.0
LGALS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22347,535,718 - 47,539,994 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12250,224,324 - 50,228,602 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02218,593,154 - 18,597,432 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12236,426,226 - 36,430,356 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2236,426,228 - 36,430,356 (+)Ensemblpanpan1.1panPan2
LGALS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11026,932,351 - 26,935,580 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1026,932,301 - 26,935,646 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1026,887,006 - 26,890,237 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01027,724,227 - 27,727,457 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,724,177 - 27,727,523 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11027,446,500 - 27,449,728 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,755,263 - 27,758,492 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01027,932,614 - 27,935,843 (-)NCBIUU_Cfam_GSD_1.0
Lgals1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494510,397,291 - 10,400,438 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364923,407,049 - 3,411,222 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364923,407,704 - 3,411,197 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LGALS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl510,149,068 - 10,156,023 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1510,149,069 - 10,152,514 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.257,642,321 - 7,645,763 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LGALS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11920,379,144 - 20,383,303 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1920,379,003 - 20,383,464 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045105,440,547 - 105,444,741 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lgals1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475210,219,872 - 10,223,317 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475210,220,115 - 10,223,434 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lgals1
104 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:244
Count of miRNA genes:215
Interacting mature miRNAs:234
Transcripts:ENSMUST00000089377
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
15092079Igly6_mIgG glycosylation 6, GP6 (mouse)157410054082674156Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155478912988789129Mouse
1558786Msq1_mMAV-1 susceptibility QTL 1 (mouse)Not determined156338964681086436Mouse
15092080Igly7_mIgG glycosylation 7, GP10 (mouse)157779491982674156Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
1301006Hfib1_mhepatic fibrogenesis 1 (mouse)Not determined154730633481306479Mouse
27095936Ulnl4_mulna length 4, 5 week (mouse)155676339687684201Mouse
10755515Amzn3_manatomical modifier of Zfp423 3 (mouse)154638964680389845Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
1301429Pcir3_mperiosteal circumference 3 (mouse)Not determined154846536282465496Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
1357756Alaa4_malopecia areata 4 (mouse)Not determined154638964680389845Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
1301433Rapop5_mradiation-induced apoptosis 5 (mouse)Not determined15927302279474762Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
10412067Pain2_mpain 2 (mouse)Not determined155164533985645626Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
4142198Hbtq_mhabituation QTL (mouse)Not determined155116070885160833Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1301568Tria2_mT-cell receptor induced activation 2 (mouse)Not determined154485914178859281Mouse
1302080Szs13_mseizure susceptibility 13 (mouse)Not determined155168583285694449Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
10045637Heal27_mwound healing/regeneration 29 (mouse)Not determined155141836185418511Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1301708Cocrb14_mcocaine related behavior 14 (mouse)Not determined155180651585806651Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
1302002Cocia2_mcocaine induced activation 2 (mouse)Not determined157237245979899178Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
13442492Mecth2_mmechanosensation threshold 2 (mouse)157466284979387201Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
1301472Pain1_mpain 1 (mouse)Not determined157532084690813185Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
1301860Gct3_mgranulosa cell tumorigenesis 3 (mouse)Not determined154740959681409691Mouse

Markers in Region
RH124926  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381578,930,101 - 78,930,263UniSTSGRCm38
MGSCv371578,760,531 - 78,760,693UniSTSGRCm37
Cytogenetic Map15EUniSTS
cM Map1544.9UniSTS
Lgals1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15EUniSTS
cM Map1544.9UniSTS
Lgals1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381578,929,998 - 78,930,176UniSTSGRCm38
MGSCv371578,760,428 - 78,760,606UniSTSGRCm37
Cytogenetic Map15EUniSTS
cM Map1544.9UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000089377   ⟹   ENSMUSP00000086795
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1578,810,925 - 78,814,665 (+)Ensembl
GRCm38.p6 Ensembl1578,926,725 - 78,930,465 (+)Ensembl
Ensembl Acc Id: ENSMUST00000229159   ⟹   ENSMUSP00000155144
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1578,810,926 - 78,814,391 (+)Ensembl
GRCm38.p6 Ensembl1578,926,726 - 78,930,191 (+)Ensembl
RefSeq Acc Id: NM_008495   ⟹   NP_032521
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391578,810,925 - 78,814,665 (+)NCBI
GRCm381578,926,725 - 78,930,465 (+)ENTREZGENE
MGSCv371578,757,155 - 78,760,895 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032521   ⟸   NM_008495
- UniProtKB: Q99M27 (UniProtKB/Swiss-Prot),   Q4FZH4 (UniProtKB/Swiss-Prot),   P17601 (UniProtKB/Swiss-Prot),   P11946 (UniProtKB/Swiss-Prot),   P05163 (UniProtKB/Swiss-Prot),   Q9D0X0 (UniProtKB/Swiss-Prot),   P16045 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000086795   ⟸   ENSMUST00000089377
Ensembl Acc Id: ENSMUSP00000155144   ⟸   ENSMUST00000229159
Protein Domains
Galectin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P16045-F1-model_v2 AlphaFold P16045 1-135 view protein structure

Promoters
RGD ID:6826143
Promoter ID:MM_KWN:19024
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_008495
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361578,756,316 - 78,757,327 (+)MPROMDB
RGD ID:6847213
Promoter ID:MM_ACW:18642
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:LGALS1.ASEP07,   LGALS1.CSEP07,   LGALS1.ESEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361578,757,676 - 78,759,057 (+)MPROMDB
RGD ID:8684294
Promoter ID:EPDNEW_M20178
Type:initiation region
Name:Lgals1_1
Description:Mus musculus lectin, galactose binding, soluble 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381578,926,726 - 78,926,786EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96777 AgrOrtholog
Ensembl Genes ENSMUSG00000068220 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000089377 ENTREZGENE
  ENSMUST00000089377.6 UniProtKB/Swiss-Prot
  ENSMUST00000229159.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/Swiss-Prot
InterPro ConA-like_dom_sf UniProtKB/Swiss-Prot
  Galectin-like UniProtKB/Swiss-Prot
  Galectin_CRD UniProtKB/Swiss-Prot
KEGG Report mmu:16852 UniProtKB/Swiss-Prot
MGD MGI:96777 ENTREZGENE
NCBI Gene 16852 ENTREZGENE
PANTHER GALECTIN-1 UniProtKB/Swiss-Prot
  PTHR11346 UniProtKB/Swiss-Prot
Pfam Gal-bind_lectin UniProtKB/Swiss-Prot
PharmGKB LGALS1 RGD
PhenoGen Lgals1 PhenoGen
PROSITE GALECTIN UniProtKB/Swiss-Prot
SMART Gal-bind_lectin UniProtKB/Swiss-Prot
  GLECT UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49899 UniProtKB/Swiss-Prot
UniProt A0A2R8VHJ0_MOUSE UniProtKB/TrEMBL
  LEG1_MOUSE UniProtKB/Swiss-Prot
  P05163 ENTREZGENE
  P11946 ENTREZGENE
  P16045 ENTREZGENE
  P17601 ENTREZGENE
  Q4FZH4 ENTREZGENE
  Q99M27 ENTREZGENE
  Q9D0X0 ENTREZGENE
UniProt Secondary P05163 UniProtKB/Swiss-Prot
  P11946 UniProtKB/Swiss-Prot
  P17601 UniProtKB/Swiss-Prot
  Q4FZH4 UniProtKB/Swiss-Prot
  Q99M27 UniProtKB/Swiss-Prot
  Q9D0X0 UniProtKB/Swiss-Prot