Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ola1 | Mouse | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of OLA1 mRNA | CTD | PMID:22206623 | Ola1 | Mouse | 1-chloro-2,4-dinitrobenzene | affects binding | ISO | OLA1 (Homo sapiens) | 6480464 | Dinitrochlorobenzene binds to OLA1 protein | CTD | PMID:32991956 | Ola1 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of OLA1 mRNA | CTD | PMID:21570461 | Ola1 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | OLA1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of OLA1 mRNA | CTD | PMID:22574217 | Ola1 | Mouse | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | decreases expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:19954255 | Ola1 | Mouse | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of OLA1 mRNA | CTD | PMID:30071829 | Ola1 | Mouse | 4,4'-sulfonyldiphenol | decreases methylation | ISO | OLA1 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of OLA1 gene | CTD | PMID:31601247 | Ola1 | Mouse | 4,4'-sulfonyldiphenol | increases expression | ISO | OLA1 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of OLA1 protein | CTD | PMID:34186270 | Ola1 | Mouse | 5-aza-2'-deoxycytidine | decreases expression | ISO | OLA1 (Homo sapiens) | 6480464 | Decitabine results in decreased expression of OLA1 mRNA | CTD | PMID:19363521 | Ola1 | Mouse | 5-aza-2'-deoxycytidine | multiple interactions | ISO | OLA1 (Homo sapiens) | 6480464 | TP53 protein affects the reaction [Decitabine results in decreased expression of OLA1 mRNA] | CTD | PMID:19363521 | Ola1 | Mouse | 6-propyl-2-thiouracil | increases expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of OLA1 mRNA | CTD | PMID:30047161 | Ola1 | Mouse | actinomycin D | multiple interactions | ISO | OLA1 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased secretion of OLA1 protein | CTD | PMID:38460933 | Ola1 | Mouse | all-trans-retinoic acid | increases expression | ISO | OLA1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of OLA1 mRNA | CTD | PMID:23724009 | Ola1 | Mouse | all-trans-retinoic acid | decreases expression | ISO | OLA1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of OLA1 mRNA | CTD | PMID:33167477 | Ola1 | Mouse | amitrole | increases expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of OLA1 mRNA | CTD | PMID:30047161 | Ola1 | Mouse | aristolochic acid A | decreases expression | ISO | OLA1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of OLA1 mRNA | CTD | PMID:33212167 | Ola1 | Mouse | aristolochic acid A | increases expression | ISO | OLA1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of OLA1 protein | CTD | PMID:33212167 | Ola1 | Mouse | arsenite(3-) | multiple interactions | ISO | OLA1 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to OLA1 mRNA] | CTD | PMID:32406909 | Ola1 | Mouse | benzatropine | increases expression | ISO | OLA1 (Homo sapiens) | 6480464 | Benztropine results in increased expression of OLA1 protein | CTD | PMID:34122009 | Ola1 | Mouse | benzo[a]pyrene | decreases methylation | ISO | OLA1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of OLA1 5' UTR | CTD | PMID:27901495 | Ola1 | Mouse | bisphenol A | affects expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of OLA1 mRNA | CTD | PMID:25181051 | Ola1 | Mouse | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of OLA1 mRNA | CTD | PMID:33221593 | Ola1 | Mouse | bisphenol A | decreases expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of OLA1 mRNA | CTD | PMID:32145629 | Ola1 | Mouse | Bisphenol B | increases expression | ISO | OLA1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of OLA1 protein | CTD | PMID:34186270 | Ola1 | Mouse | Brodifacoum | increases expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | bromfenacoum results in increased expression of OLA1 protein | CTD | PMID:28903499 | Ola1 | Mouse | buspirone | decreases expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | Buspirone results in decreased expression of OLA1 mRNA | CTD | PMID:24136188 | Ola1 | Mouse | butanal | increases expression | ISO | OLA1 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of OLA1 mRNA | CTD | PMID:26079696 | Ola1 | Mouse | carbon nanotube | multiple interactions | ISO | OLA1 (Homo sapiens) | 6480464 | [Nanotubes and Carbon co-treated with calfactant] results in increased expression of OLA1 protein | CTD | PMID:23026733 | Ola1 | Mouse | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | Ola1 | Mouse | clofibric acid | affects expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | Clofibric Acid affects the expression of OLA1 mRNA | CTD | PMID:17602206 | Ola1 | Mouse | clofibric acid | multiple interactions | ISO | Ola1 (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of OLA1 mRNA | CTD | PMID:17602206 | Ola1 | Mouse | cocaine | affects expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | Cocaine affects the expression of OLA1 mRNA | CTD | PMID:20187946 | Ola1 | Mouse | copper(II) sulfate | increases expression | ISO | OLA1 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of OLA1 mRNA | CTD | PMID:19549813 | Ola1 | Mouse | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of OLA1 mRNA | CTD | PMID:21266533 | Ola1 | Mouse | dioxygen | multiple interactions | EXP | | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of OLA1 mRNA | CTD | PMID:30529165 | Ola1 | Mouse | dorsomorphin | multiple interactions | ISO | OLA1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Ola1 | Mouse | doxorubicin | decreases expression | ISO | OLA1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of OLA1 mRNA | CTD | PMID:29803840 | Ola1 | Mouse | elemental selenium | decreases expression | ISO | OLA1 (Homo sapiens) | 6480464 | Selenium results in decreased expression of OLA1 mRNA | CTD | PMID:19244175 | Ola1 | Mouse | enzyme inhibitor | multiple interactions | ISO | OLA1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of OLA1 protein | CTD | PMID:23301498 | Ola1 | Mouse | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of OLA1 mRNA | CTD | PMID:30319688 | Ola1 | Mouse | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of OLA1 mRNA | CTD | PMID:30319688 | Ola1 | Mouse | fenthion | increases expression | EXP | | 6480464 | Fenthion results in increased expression of OLA1 mRNA | CTD | PMID:34813904 | Ola1 | Mouse | flutamide | increases expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of OLA1 mRNA | CTD | PMID:24136188 | Ola1 | Mouse | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of OLA1 mRNA | CTD | PMID:22206623 | Ola1 | Mouse | furan | increases methylation | ISO | Ola1 (Rattus norvegicus) | 6480464 | furan results in increased methylation of OLA1 gene | CTD | PMID:22079235 | Ola1 | Mouse | glafenine | increases expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | Glafenine results in increased expression of OLA1 mRNA | CTD | PMID:24136188 | Ola1 | Mouse | hydrogen peroxide | affects expression | ISO | OLA1 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of OLA1 mRNA | CTD | PMID:20044591 | Ola1 | Mouse | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of OLA1 mRNA | CTD | PMID:36331819 | Ola1 | Mouse | ivermectin | decreases expression | ISO | OLA1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of OLA1 protein | CTD | PMID:32959892 | Ola1 | Mouse | lead(0) | affects splicing | ISO | OLA1 (Homo sapiens) | 6480464 | Lead affects the splicing of OLA1 mRNA | CTD | PMID:28903495 | Ola1 | Mouse | methidathion | increases expression | EXP | | 6480464 | methidathion results in increased expression of OLA1 mRNA | CTD | PMID:34813904 | Ola1 | Mouse | methimazole | increases expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of OLA1 mRNA | CTD | PMID:30047161 | Ola1 | Mouse | methylmercury chloride | decreases expression | ISO | OLA1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of OLA1 mRNA | CTD | PMID:28001369 | Ola1 | Mouse | N-nitrosodiethylamine | multiple interactions | ISO | Ola1 (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of OLA1 mRNA | CTD | PMID:17602206 | Ola1 | Mouse | Nutlin-3 | multiple interactions | ISO | OLA1 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased secretion of OLA1 protein | CTD | PMID:38460933 | Ola1 | Mouse | oxaliplatin | multiple interactions | ISO | Ola1 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of OLA1 mRNA | CTD | PMID:25729387 | Ola1 | Mouse | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of OLA1 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of OLA1 mRNA | CTD | PMID:34911549 | Ola1 | Mouse | ozone | multiple interactions | ISO | OLA1 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of OLA1 mRNA | CTD | PMID:35430440 | Ola1 | Mouse | panobinostat | multiple interactions | ISO | OLA1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of OLA1 mRNA | CTD | PMID:27188386 | Ola1 | Mouse | panobinostat | decreases expression | ISO | OLA1 (Homo sapiens) | 6480464 | panobinostat results in decreased expression of OLA1 mRNA | CTD | PMID:26272509 | Ola1 | Mouse | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of OLA1 mRNA | CTD | PMID:17562736 | Ola1 | Mouse | pentanal | increases expression | ISO | OLA1 (Homo sapiens) | 6480464 | pentanal results in increased expression of OLA1 mRNA | CTD | PMID:26079696 | Ola1 | Mouse | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of OLA1 mRNA | CTD | PMID:36331819 | Ola1 | Mouse | phenylmercury acetate | decreases expression | ISO | OLA1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of OLA1 mRNA | CTD | PMID:26272509 | Ola1 | Mouse | phenylmercury acetate | multiple interactions | ISO | OLA1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of OLA1 mRNA | CTD | PMID:27188386 | Ola1 | Mouse | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of OLA1 mRNA | CTD | PMID:19162173 | Ola1 | Mouse | Propiverine | affects binding | ISO | Ola1 (Rattus norvegicus) | 6480464 | propiverine binds to OLA1 protein | CTD | PMID:29273565 | Ola1 | Mouse | quinoline | decreases expression | ISO | OLA1 (Homo sapiens) | 6480464 | quinoline analog results in decreased expression of OLA1 protein | CTD | PMID:18645022 | Ola1 | Mouse | SB 431542 | multiple interactions | ISO | OLA1 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | Ola1 | Mouse | selenium atom | decreases expression | ISO | OLA1 (Homo sapiens) | 6480464 | Selenium results in decreased expression of OLA1 mRNA | CTD | PMID:19244175 | Ola1 | Mouse | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of OLA1 protein | CTD | PMID:29044176 | Ola1 | Mouse | sodium fluoride | decreases expression | EXP | | 6480464 | Sodium Fluoride results in decreased expression of OLA1 mRNA and Sodium Fluoride results in decreased expression of OLA1 protein | CTD | PMID:27862939 and PMID:28918527 | Ola1 | Mouse | sulfadimethoxine | increases expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of OLA1 mRNA | CTD | PMID:30047161 | Ola1 | Mouse | sunitinib | decreases expression | ISO | OLA1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of OLA1 mRNA | CTD | PMID:31533062 | Ola1 | Mouse | tert-butyl hydroperoxide | increases expression | ISO | OLA1 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in increased expression of OLA1 mRNA | CTD | PMID:15336504 | Ola1 | Mouse | thapsigargin | increases expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | Thapsigargin results in increased expression of OLA1 protein | CTD | PMID:35544339 | Ola1 | Mouse | thioacetamide | increases expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of OLA1 mRNA | CTD | PMID:34492290 | Ola1 | Mouse | titanium dioxide | decreases methylation | EXP | | 6480464 | titanium dioxide results in decreased methylation of OLA1 gene | CTD | PMID:35295148 | Ola1 | Mouse | topotecan | multiple interactions | ISO | Ola1 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of OLA1 mRNA | CTD | PMID:25729387 | Ola1 | Mouse | trichostatin A | decreases expression | ISO | OLA1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of OLA1 mRNA | CTD | PMID:24935251 and PMID:26272509 | Ola1 | Mouse | trichostatin A | multiple interactions | ISO | OLA1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of OLA1 mRNA | CTD | PMID:27188386 | Ola1 | Mouse | trimellitic anhydride | increases expression | EXP | | 6480464 | trimellitic anhydride results in increased expression of OLA1 mRNA | CTD | PMID:19042947 | Ola1 | Mouse | triphenyl phosphate | affects expression | ISO | Ola1 (Rattus norvegicus) | 6480464 | triphenyl phosphate affects the expression of OLA1 mRNA | CTD | PMID:30589522 | Ola1 | Mouse | triptonide | decreases expression | EXP | | 6480464 | triptonide results in decreased expression of OLA1 mRNA | CTD | PMID:33045310 | Ola1 | Mouse | valproic acid | decreases expression | ISO | OLA1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of OLA1 mRNA | CTD | PMID:24383497 more ... | Ola1 | Mouse | valproic acid | multiple interactions | ISO | OLA1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of OLA1 mRNA | CTD | PMID:27188386 | |