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Gene: Pdia6 (protein disulfide isomerase associated 6) Mus musculus
Symbol: Pdia6
Name: protein disulfide isomerase associated 6
Description: Exhibits enzyme inhibitor activity and peptide disulfide oxidoreductase activity. Involved in negative regulation of IRE1-mediated unfolded protein response. Localizes to endoplasmic reticulum chaperone complex. Is expressed in embryo; liver; lung epithelium; and pancreas epithelium. Orthologous to human PDIA6 (protein disulfide isomerase family A member 6); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; etoposide pharmacodynamics pathway; INTERACTS WITH (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1H-pyrazole.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700015E05Rik; AL023058; C77895; CaBP5; P5; protein disulfide isomerase-related protein; protein disulfide-isomerase A6; thioredoxin domain containing 7; thioredoxin domain-containing protein 7; Txndc7
Homo sapiens (human) : PDIA6 (protein disulfide isomerase family A member 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pdia6 (protein disulfide isomerase family A, member 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdia6 (protein disulfide isomerase family A member 6)
Pan paniscus (bonobo/pygmy chimpanzee) : PDIA6 (protein disulfide isomerase family A member 6)
Canis lupus familiaris (dog) : PDIA6 (protein disulfide isomerase family A member 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdia6 (protein disulfide isomerase family A member 6)
Sus scrofa (pig) : PDIA6 (protein disulfide isomerase family A member 6)
Chlorocebus sabaeus (African green monkey) : PDIA6 (protein disulfide isomerase family A member 6)
Heterocephalus glaber (naked mole-rat) : Pdia6 (protein disulfide isomerase family A member 6)
more info ...
Related Pseudogenes: Gm6655  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1217,266,545 - 17,284,770 (+)EnsemblGRCm38mm10GRCm38
GRCm381217,266,589 - 17,284,785 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371217,273,401 - 17,291,576 (+)NCBIGRCm37mm9NCBIm37
MGSCv361217,292,075 - 17,310,250 (+)NCBImm8
Celera1221,149,080 - 21,150,652 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pdia6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553668
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.