Ppp1r12a (protein phosphatase 1, regulatory subunit 12A) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Ppp1r12a (protein phosphatase 1, regulatory subunit 12A) Mus musculus
Analyze
Symbol: Ppp1r12a
Name: protein phosphatase 1, regulatory subunit 12A
RGD ID: 732779
MGI Page MGI
Description: Predicted to enable several functions, including 14-3-3 protein binding activity; myosin phosphatase regulator activity; and protein kinase binding activity. Acts upstream of or within cellular response to xenobiotic stimulus; protein dephosphorylation; and regulation of nucleocytoplasmic transport. Located in A band and Z disc. Is expressed in several structures, including genital tubercle epithelium; sciatic nerve; telencephalon; urethra epithelium; and urothelium. Orthologous to human PPP1R12A (protein phosphatase 1 regulatory subunit 12A).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1200015F06Rik; 5730577I22Rik; AA792106; AV099298; D10Ertd625; D10Ertd625e; MGC159084; myosin phosphatase target subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; Mypt; Mypt1; protein phosphatase 1 regulatory subunit 12A
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910107,997,913 - 108,115,846 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10107,998,054 - 108,120,336 (+)EnsemblGRCm39 Ensembl
GRCm3810108,162,092 - 108,279,985 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10108,162,193 - 108,284,475 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710107,599,456 - 107,714,631 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610107,566,219 - 107,688,585 (+)NCBIMGSCv36mm8
Celera10110,096,336 - 110,211,438 (+)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1056.33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(R)-noradrenaline  (ISO)
1,2-dimethylhydrazine  (EXP)
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine  (ISO)
1-octadec-9-enoylglycero-3-phosphate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-nitrotoluene  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
4-vinylcyclohexene dioxide  (EXP)
acetylsalicylic acid  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
aldrithiol  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (EXP)
atrasentan  (ISO)
benzatropine  (ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
Brodifacoum  (ISO)
bromochloroacetic acid  (ISO)
caffeine  (ISO)
capsaicin  (ISO)
capsazepine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
chlordecone  (EXP)
chloroprene  (ISO)
cisplatin  (ISO)
cocaine  (ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
Cuprizon  (ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (ISO)
dibenziodolium  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dioxygen  (EXP,ISO)
diuron  (ISO)
dorsomorphin  (EXP,ISO)
doxorubicin  (ISO)
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor  (ISO)
endosulfan  (ISO)
enzyme inhibitor  (ISO)
fasudil  (ISO)
fluvastatin  (ISO)
folic acid  (EXP)
FR900359  (ISO)
genistein  (ISO)
gentamycin  (ISO)
geranylgeraniol  (ISO)
glucose  (ISO)
glycodeoxycholic acid  (ISO)
glycyrrhetinate  (ISO)
glycyrrhetinic acid  (ISO)
guanosine 5'-[gamma-thio]triphosphate  (ISO)
hexadecanoic acid  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (EXP)
hydroxyurea  (EXP)
ivermectin  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methyl methanesulfonate  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
nickel atom  (EXP)
notoginsenoside R1  (ISO)
oxaliplatin  (ISO)
p-anisidine  (EXP)
paclitaxel  (EXP)
paraquat  (ISO)
permethrin  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP)
phenylephrine  (ISO)
phorbol 12,13-dibutanoate  (ISO)
potassium chloride  (ISO)
potassium chromate  (ISO)
propiconazole  (EXP)
prostaglandin D2  (EXP)
quercetin  (ISO)
razoxane  (ISO)
resveratrol  (EXP,ISO)
simvastatin  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium fluoride  (EXP)
streptozocin  (ISO)
testosterone enanthate  (ISO)
thapsigargin  (EXP)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trans-piceid  (ISO)
triptonide  (EXP)
tungsten  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
Y-27632  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
A band  (IBA,IDA)
actin cytoskeleton  (ISO)
centrosome  (ISO,ISS)
contractile muscle fiber  (ISO)
cytoplasm  (IBA)
cytosol  (IEA,ISO)
kinetochore  (ISO,ISS)
nucleolus  (IEA,ISO)
plasma membrane  (IEA,ISO)
PTW/PP1 phosphatase complex  (ISO,ISS)
stress fiber  (IEA)
Z disc  (IBA,IDA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8662509   PMID:8889548   PMID:9701556   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11067852   PMID:11076861   PMID:11342221   PMID:11544199   PMID:12477932   PMID:12520002  
PMID:12904583   PMID:14610273   PMID:15071095   PMID:15782199   PMID:15999227   PMID:16141072   PMID:16141073   PMID:16145842   PMID:16574904   PMID:16602821   PMID:17369396   PMID:17369465  
PMID:17825250   PMID:17967808   PMID:18079119   PMID:18448676   PMID:18524939   PMID:18669920   PMID:18714354   PMID:18799693   PMID:18840611   PMID:19437030   PMID:19701191   PMID:19939965  
PMID:20634291   PMID:21177343   PMID:21303848   PMID:21677750   PMID:21873635   PMID:21880919   PMID:21883701   PMID:21895889   PMID:22437831   PMID:22544752   PMID:23168335   PMID:23419712  
PMID:23499953   PMID:24835173   PMID:24929853   PMID:24951589   PMID:25428883   PMID:25433069   PMID:25724497   PMID:26365490   PMID:26526197   PMID:27084390   PMID:27101932   PMID:27129938  
PMID:28634551   PMID:28671696   PMID:29111324   PMID:29254152   PMID:29395909   PMID:29518331   PMID:29669786   PMID:29694711   PMID:30196744   PMID:30228103   PMID:30234377   PMID:30446640  
PMID:30740930   PMID:31638192   PMID:31759145   PMID:31883643   PMID:32325033   PMID:32511952   PMID:32581705   PMID:33145641   PMID:33482876   PMID:33574455   PMID:33932897   PMID:34019870  
PMID:34553133   PMID:35107022   PMID:35670107   PMID:35879418   PMID:36175407   PMID:36843141   PMID:36890135   PMID:37142655   PMID:38934703  


Genomics

Comparative Map Data
Ppp1r12a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910107,997,913 - 108,115,846 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10107,998,054 - 108,120,336 (+)EnsemblGRCm39 Ensembl
GRCm3810108,162,092 - 108,279,985 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10108,162,193 - 108,284,475 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710107,599,456 - 107,714,631 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610107,566,219 - 107,688,585 (+)NCBIMGSCv36mm8
Celera10110,096,336 - 110,211,438 (+)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1056.33NCBI
PPP1R12A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381279,773,563 - 79,935,460 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1279,773,563 - 79,935,460 (-)EnsemblGRCh38hg38GRCh38
GRCh371280,167,343 - 80,329,240 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361278,692,317 - 78,852,842 (-)NCBINCBI36Build 36hg18NCBI36
Build 341278,670,653 - 78,831,179NCBI
Celera1279,833,868 - 79,995,723 (-)NCBICelera
Cytogenetic Map12q21.2-q21.31NCBI
HuRef1277,223,683 - 77,385,520 (-)NCBIHuRef
CHM1_11280,133,789 - 80,295,575 (-)NCBICHM1_1
T2T-CHM13v2.01279,752,233 - 79,914,115 (-)NCBIT2T-CHM13v2.0
Ppp1r12a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8745,368,922 - 45,480,158 (+)NCBIGRCr8
mRatBN7.2743,482,808 - 43,593,689 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl743,482,803 - 43,593,425 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx745,390,762 - 45,499,381 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0747,593,881 - 47,702,502 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0747,371,635 - 47,480,244 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0751,404,971 - 51,515,382 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl751,404,919 - 51,515,373 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0751,417,546 - 51,527,960 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4746,876,552 - 46,986,022 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1746,896,822 - 47,006,293 (+)NCBI
Celera740,349,341 - 40,458,007 (+)NCBICelera
Cytogenetic Map7q21NCBI
Ppp1r12a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540518,596,541 - 18,727,345 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540518,594,191 - 18,727,345 (-)NCBIChiLan1.0ChiLan1.0
PPP1R12A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21087,826,297 - 87,990,301 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11287,822,433 - 87,986,517 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01277,306,155 - 77,459,455 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11280,153,348 - 80,316,131 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1280,155,702 - 80,314,601 (-)Ensemblpanpan1.1panPan2
PPP1R12A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11522,272,291 - 22,413,441 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1522,274,259 - 22,414,359 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1522,698,781 - 22,837,753 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01522,634,434 - 22,773,680 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1522,634,483 - 22,773,936 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11522,210,562 - 22,351,199 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01522,271,520 - 22,410,758 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01522,511,839 - 22,651,103 (-)NCBIUU_Cfam_GSD_1.0
Ppp1r12a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494537,963,878 - 38,100,776 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936698817,943 - 948,368 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936698811,399 - 948,631 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP1R12A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl5101,490,341 - 101,639,429 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.15101,490,282 - 101,639,456 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25106,491,071 - 106,610,181 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PPP1R12A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11175,300,278 - 75,461,498 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1175,319,962 - 75,461,438 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037169,985,567 - 170,152,231 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp1r12a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475018,363,913 - 18,501,243 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475018,363,618 - 18,498,630 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ppp1r12a
4218 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:127
Count of miRNA genes:121
Interacting mature miRNAs:124
Transcripts:ENSMUST00000070663
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301520Uvbi1_mUVB induced immunosuppression 1 (mouse)Not determined1086909085120909229Mouse
4142137Femwf3_mfemur work to failure 3 (mouse)Not determined75338568109338767Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
4142386Tgq20_mtriglyceride QTL 20 (mouse)Not determined88836456122836456Mouse
1357594Estoq3_membryo survival total QTL 3 (mouse)Not determined1084079650122041528Mouse
4141361Cfmq3_mcystic fibrosis modifier QTL 3 (mouse)Not determined10101497164130530862Mouse
4141487Tgq21_mtriglyceride QTL 21 (mouse)Not determined104110021130530862Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
1301895Exq1_mexploratory and excitability QTL 1 (mouse)Not determined10102847852130530862Mouse
14746996Manh69_mmandible shape 69 (mouse)10104763638130530862Mouse
4141479W10q8_mweight 10 weeks QTL 8 (mouse)Not determined84079650122041528Mouse
14747004Mancz8_mmandible centroid size 8 (mouse)1082078412116078412Mouse
1301901Im5_mimmunoregulatory 5 (mouse)Not determined10101497164130530862Mouse
4142496W6q8_mweight 6 weeks QTL 8 (mouse)Not determined84079650122041528Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1044876096115935905Mouse
1357622Espq3_membryo survival preimplantation QTL 3 (mouse)Not determined1084079650122041528Mouse
4142365Egq9_mearly growth QTL 9 (mouse)Not determined84079650122041528Mouse
13208554Lgth11_mbody length 11 (mouse)1090835862120835905Mouse
1357744Cfbw4_mcystic fibrosis body weight 4 (mouse)Not determined10100986516130530862Mouse
1300921Skl4_mskeletal size (tail length) 4 (mouse)Not determined1088088254122088391Mouse
1302200Sle12_msystematic lupus erythematosus susceptibility 12 (mouse)Not determined10105041304130530862Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045476096120635905Mouse
1300797Sluc22_msusceptibility to lung cancer 22 (mouse)Not determined1086713608120713756Mouse
11251717Siim1_mstress induced immobility 1 (mouse)1078381268112381268Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069735830130430862Mouse
11039516Ltpr5_mLeishmania tropica response 5 (mouse)1090506901125575232Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
13208560Wght9_mweight 9 (mouse)1059835822120835905Mouse
1301165Lith7_mlithogenic gene 7 (mouse)Not determined1082309418116309657Mouse
1357482Nhdlq4_mnon-HDL QTL 4 (mouse)Not determined10105041304130530862Mouse
26884388Skwq7_mskull length QTL 7, 10 week (mouse)10101735861113735905Mouse
1300908Insq4_minsulin QTL 4 (mouse)Not determined1086909085120909229Mouse
4141054mwfh_mmodifier of white forlock hypopigmentation (mouse)Not determined83017003117017136Mouse
4142461Bmd25_mbone mineral density 25 (mouse)Not determined1097217101130530862Mouse
1301968Estq4_mestradiol regulated response QTL 4 (mouse)Not determined10100986516130530862Mouse
4142074Tmevp2_mTheiler's murine encephalomyelitis virus persistence 2 (mouse)Not determined92729941111568319Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1073987216125515907Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067335830111735905Mouse
1357779Tesq3_mtestis weight QTL 3 (mouse)Not determined1084079650122041528Mouse
11059552Lmr32c_mleishmaniasis resistance 32c (mouse)1099309418116220862Mouse
11059553Lmr32d_mleishmaniasis resistance 32d (mouse)1082309418116309657Mouse
11059554Lmr32e_mleishmaniasis resistance 32e (mouse)1082309418116309657Mouse
11059555Lmr32f_mleishmaniasis resistance 32f (mouse)1082309418116309657Mouse
11533921Mvb2_mmodifier of vibrator 2 (mouse)1097217101130530862Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
1357638Cia29_mcollagen induced arthritis 29 (mouse)Not determined1085454982118497353Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1063935779115935905Mouse
1357632Vtbt9_mvertebral trabecular bone trait 9 (mouse)Not determined1075338568109338767Mouse
1300679Nociq2_mnociceptive sensitivity inflammatory QTL 2 (mouse)Not determined10105041304130530862Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1067835830124835905Mouse
1300678Leg2_mlongevity extending gene 2 (mouse)Not determined10102506908130530862Mouse
12880413V125Dq9_mvitamin D active form serum level QTL 9 (mouse)1097535905130530862Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1073987216125515907Mouse
4141402T2dm1sa_mtype 2 diabetes mellitus 1 in SMXA RI mice (mouse)Not determined97758644130530862Mouse
4141269Ipng2_mimprinted postnatal growth 2 (mouse)Not determined105088254118497353Mouse
1301758Fcsa3_mfemoral cross-sectional area 3 (mouse)Not determined1089927651123927754Mouse
4141007Obrq10_mobesity resistance QTL 10 (mouse)Not determined103243727130530862Mouse
10043881Adip24_madiposity 24 (mouse)Not determined1082392803116392952Mouse
11533919Mvb4_mmodifier of vibrator 4 (mouse)397217101130530862Mouse
11059544Lmr32_mleishmaniasis resistance 32 (mouse)1099309418116220862Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
4141387Lgaq5_mlate growth adjusted QTL 5 (mouse)Not determined84079650122041528Mouse
11059550Lmr32a_mleishmaniasis resistance 32a (mouse)1082309418116309657Mouse
11059551Lmr32b_mleishmaniasis resistance 32b (mouse)1082309418116309657Mouse
14696727Kidrq2_mkidney weight, right QTL 2 (mouse)10102902508130530862Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059335822122335905Mouse
11040593Lmr5e_mleishmaniasis resistance 5e (mouse)1099220635130530862Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
27226725Tibw1_mtibia width 1, proximal, 5 week (mouse)10102735861123235905Mouse
11040594Lmr5f_mleishmaniasis resistance 5f (mouse)10105179713130530862Mouse
11040595Lmr5c_mleishmaniasis resistance 5c (mouse)1099220635130530862Mouse
1357544Vtbt10_mvertebral trabecular bone trait 10 (mouse)Not determined1097217101130530862Mouse
1300975Fembrs3_mfemur breaking strength 3 (mouse)Not determined1075338568109338767Mouse
11040596Lmr5d_mleishmaniasis resistance 5d (mouse)10105179713130530862Mouse
11040597Lmr5a_mleishmaniasis resistance 5a (mouse)1099220635130530862Mouse
11040598Lmr5b_mleishmaniasis resistance 5b (mouse)10105179713130530862Mouse

Markers in Region
AV099298  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810108,277,382 - 108,277,461UniSTSGRCm38
MGSCv3710107,714,438 - 107,714,517UniSTSGRCm37
Celera10110,211,245 - 110,211,324UniSTS
Cytogenetic Map10CUniSTS
cM Map1058.0UniSTS
Whitehead/MRC_RH101179.98UniSTS
MHAa53c6.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810108,185,443 - 108,185,613UniSTSGRCm38
MGSCv3710107,622,499 - 107,622,669UniSTSGRCm37
Celera10110,119,368 - 110,119,538UniSTS
Cytogenetic Map10CUniSTS
cM Map1058.0UniSTS
Whitehead_YAC10 UniSTS
D10Ertd625e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810108,278,772 - 108,278,983UniSTSGRCm38
MGSCv3710107,715,828 - 107,716,039UniSTSGRCm37
Celera10110,212,635 - 110,212,846UniSTS
Cytogenetic Map10CUniSTS
cM Map1058.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001368736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001368737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_027892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006513327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006513329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB042280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC139335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC054076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC125381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC137630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000070663   ⟹   ENSMUSP00000069257
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10107,998,261 - 108,113,436 (+)Ensembl
GRCm38.p6 Ensembl10108,162,400 - 108,277,575 (+)Ensembl
Ensembl Acc Id: ENSMUST00000218161
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10108,088,971 - 108,115,845 (+)Ensembl
GRCm38.p6 Ensembl10108,253,110 - 108,279,984 (+)Ensembl
Ensembl Acc Id: ENSMUST00000218773
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10108,085,478 - 108,089,337 (+)Ensembl
GRCm38.p6 Ensembl10108,249,617 - 108,253,476 (+)Ensembl
Ensembl Acc Id: ENSMUST00000219068
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10108,088,233 - 108,089,222 (+)Ensembl
GRCm38.p6 Ensembl10108,252,372 - 108,253,361 (+)Ensembl
Ensembl Acc Id: ENSMUST00000219263   ⟹   ENSMUSP00000151842
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10107,998,054 - 108,113,212 (+)Ensembl
GRCm38.p6 Ensembl10108,162,193 - 108,277,351 (+)Ensembl
Ensembl Acc Id: ENSMUST00000219559
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10108,104,431 - 108,120,336 (+)Ensembl
GRCm38.p6 Ensembl10108,268,570 - 108,284,475 (+)Ensembl
Ensembl Acc Id: ENSMUST00000219653
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10108,102,958 - 108,105,217 (+)Ensembl
GRCm38.p6 Ensembl10108,267,097 - 108,269,356 (+)Ensembl
Ensembl Acc Id: ENSMUST00000219759   ⟹   ENSMUSP00000151478
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10108,085,455 - 108,115,845 (+)Ensembl
GRCm38.p6 Ensembl10108,249,594 - 108,279,984 (+)Ensembl
RefSeq Acc Id: NM_001368736   ⟹   NP_001355665
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910107,997,959 - 108,115,846 (+)NCBI
GRCm3810108,162,098 - 108,279,985 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001368737   ⟹   NP_001355666
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910107,997,959 - 108,115,846 (+)NCBI
GRCm3810108,162,098 - 108,279,985 (+)NCBI
Sequence:
RefSeq Acc Id: NM_027892   ⟹   NP_082168
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910107,997,959 - 108,115,846 (+)NCBI
GRCm3810108,162,098 - 108,279,985 (+)NCBI
MGSCv3710107,599,456 - 107,714,631 (+)RGD
Celera10110,096,336 - 110,211,438 (+)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006513327   ⟹   XP_006513390
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910107,997,923 - 108,115,512 (+)NCBI
GRCm3810108,162,092 - 108,279,651 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006513329   ⟹   XP_006513392
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910107,997,913 - 108,115,512 (+)NCBI
GRCm3810108,162,092 - 108,279,651 (+)NCBI
Sequence:
RefSeq Acc Id: NP_082168   ⟸   NM_027892
- Peptide Label: isoform 2
- UniProtKB: Q9DBR7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006513392   ⟸   XM_006513329
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006513390   ⟸   XM_006513327
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001355665   ⟸   NM_001368736
- Peptide Label: isoform 1
- UniProtKB: Q9DBR7 (UniProtKB/Swiss-Prot),   Q8CBV2 (UniProtKB/Swiss-Prot),   Q05A74 (UniProtKB/Swiss-Prot),   Q99NB6 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001355666   ⟸   NM_001368737
- Peptide Label: isoform 3
Ensembl Acc Id: ENSMUSP00000069257   ⟸   ENSMUST00000070663
Ensembl Acc Id: ENSMUSP00000151842   ⟸   ENSMUST00000219263
Ensembl Acc Id: ENSMUSP00000151478   ⟸   ENSMUST00000219759
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9DBR7-F1-model_v2 AlphaFold Q9DBR7 1-1029 view protein structure

Promoters
RGD ID:6819760
Promoter ID:MM_KWN:5571
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000105279,   NM_027892,   UC007GZD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3610107,598,446 - 107,599,627 (+)MPROMDB
RGD ID:6819762
Promoter ID:MM_KWN:5573
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day4,   3T3L1_Day6
Transcripts:UC007GZE.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3610107,686,031 - 107,686,531 (+)MPROMDB
RGD ID:8673222
Promoter ID:EPDNEW_M14641
Type:multiple initiation site
Name:Ppp1r12a_1
Description:Mus musculus protein phosphatase 1, regulatory subunit 12A ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3810108,162,402 - 108,162,462EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1309528 AgrOrtholog
Ensembl Genes ENSMUSG00000019907 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000070663 ENTREZGENE
  ENSMUST00000070663.6 UniProtKB/Swiss-Prot
  ENSMUST00000219263 ENTREZGENE
  ENSMUST00000219263.2 UniProtKB/Swiss-Prot
  ENSMUST00000219759.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/Swiss-Prot
  6.10.140.390 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.250.1820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/Swiss-Prot
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot
  MYPT1/MYPT2/Mbs85 UniProtKB/Swiss-Prot
  PP1_Regulatory_Subunit UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRKG1_interact UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:17931 UniProtKB/Swiss-Prot
MGD MGI:1309528 ENTREZGENE
NCBI Gene 17931 ENTREZGENE
PANTHER PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/Swiss-Prot
  PRKG1_interact UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ppp1r12a PhenoGen
PIRSF PP1_12ABC_vert UniProtKB/Swiss-Prot
PRINTS ANKYRIN UniProtKB/Swiss-Prot
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot
  ANK_REPEAT UniProtKB/Swiss-Prot
SMART ANK UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48403 UniProtKB/Swiss-Prot
UniProt A0A1W2P750_MOUSE UniProtKB/TrEMBL
  MYPT1_MOUSE UniProtKB/Swiss-Prot
  Q05A74 ENTREZGENE
  Q3TS88_MOUSE UniProtKB/TrEMBL
  Q8CBV2 ENTREZGENE
  Q99NB6 ENTREZGENE
  Q9DBR7 ENTREZGENE
UniProt Secondary Q05A74 UniProtKB/Swiss-Prot
  Q8CBV2 UniProtKB/Swiss-Prot
  Q99NB6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-29 Ppp1r12a  protein phosphatase 1, regulatory subunit 12A    protein phosphatase 1, regulatory (inhibitor) subunit 12A  Symbol and/or name change 5135510 APPROVED