Rnf7 (ring finger protein 7) - Rat Genome Database

Name: Rnf7
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Rnf7 (ring finger protein 7) Mus musculus

Analyze

Symbol:

Rnf7

Name:

ring finger protein 7

RGD ID:

1322299

MGI Page

MGI

Description:

Predicted to enable NEDD8 ligase activity; cullin family protein binding activity; and ubiquitin protein ligase activity. Acts upstream of or within several processes, including apoptotic mitochondrial changes; brain development; and intrinsic apoptotic signaling pathway in response to oxidative stress. Located in cytoplasm and nucleus. Is expressed in central nervous system; eye; and genitourinary system. Orthologous to human RNF7 (ring finger protein 7).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Rbx; Rbx2; RING-box protein 2; S; SAG; sensitive to apoptosis gene protein

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RNF7 (ring finger protein 7)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Rnf7 (ring finger protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rnf7 (ring finger protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RNF7 (ring finger protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RNF7 (ring finger protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rnf7 (ring finger protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RNF7 (ring finger protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RNF7 (ring finger protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rnf7 (ring finger protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Rnf7 (ring finger protein 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	RNF7 (ring finger protein 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	rnf7 (ring finger protein 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Roc2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rbx-2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rnf7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Related Pseudogenes:

Gm35144 Rnf7l

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	96,352,990 - 96,360,728 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	96,352,990 - 96,360,728 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	96,470,937 - 96,478,675 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	96,470,937 - 96,478,675 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	96,371,376 - 96,379,014 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	96,280,289 - 96,327,074 (-)	NCBI		MGSCv36	mm8
Celera	9	96,029,356 - 96,036,994 (-)	NCBI		Celera
Cytogenetic Map	9	E3.3	NCBI
cM Map	9	50.63	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP)

2-hydroxypropanoic acid (ISO)

6-propyl-2-thiouracil (ISO)

aconitine (ISO)

all-trans-retinoic acid (EXP,ISO)

amitrole (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

bisphenol A (ISO)

CGP 52608 (ISO)

chromium(6+) (EXP)

clofibrate (EXP)

cobalt dichloride (ISO)

cyclosporin A (ISO)

dieldrin (ISO)

doxorubicin (ISO)

enzyme inhibitor (ISO)

epoxiconazole (EXP)

ethanol (EXP)

flutamide (ISO)

folic acid (EXP)

glafenine (ISO)

ivermectin (ISO)

lead(0) (ISO)

methimazole (ISO)

methyl methanesulfonate (ISO)

miconazole (EXP)

N-methyl-4-phenylpyridinium (ISO)

nefazodone (ISO)

nimesulide (ISO)

ozone (ISO)

paracetamol (ISO)

pirinixic acid (EXP)

pregnenolone 16alpha-carbonitrile (ISO)

rac-lactic acid (ISO)

reactive oxygen species (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

sulfadimethoxine (ISO)

tamoxifen (EXP)

tetrachloromethane (EXP)

tolcapone (ISO)

tungsten (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic mitochondrial changes (IDA)

cerebral cortex radially oriented cell migration (IGI,IMP)

intrinsic apoptotic signaling pathway in response to oxidative stress (IDA)

negative regulation of apoptotic process (IDA)

protein neddylation (ISO)

protein ubiquitination (IBA)

radial glia guided migration of Purkinje cell (IGI,IMP)

ubiquitin-dependent protein catabolic process (IBA)

Cellular Component

Cul5-RING ubiquitin ligase complex (IBA,ISO)

cytoplasm (IDA)

cytosol (ISO,TAS)

nucleoplasm (ISO)

nucleus (IBA,IDA)

Molecular Function

cullin family protein binding (IBA,ISO)

metal ion binding (IEA)

NEDD8 ligase activity (ISO)

protein binding (IPI)

ubiquitin protein ligase activity (IBA)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

ubiquitin/proteasome degradation pathway (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal angiogenesis (IAGP)

abnormal cell cycle (IAGP)

abnormal cell differentiation (IAGP)

abnormal cerebellar layer morphology (IAGP)

abnormal cerebellum development (IAGP)

abnormal cortical marginal zone morphology (IAGP)

abnormal cortical plate morphology (IAGP)

abnormal neuronal migration (IAGP)

abnormal response to tactile stimuli (IEA)

abnormal visceral yolk sac blood island morphology (IAGP)

abnormal vitelline vasculature morphology (IAGP)

decreased angiogenesis (IAGP)

decreased cell proliferation (IAGP)

decreased cerebellar granule cell precursor proliferation (IAGP)

decreased circulating chloride level (IEA)

decreased circulating triglyceride level (IEA)

decreased lung tumor incidence (IAGP)

delaminated Purkinje cell layer (IAGP)

ectopic Purkinje cell (IAGP)

embryonic growth retardation (IAGP)

embryonic lethality during organogenesis, complete penetrance (IAGP)

enlarged brain ventricles (IAGP)

hydrocephaly (IAGP)

increased apoptosis (IAGP)

increased cellular sensitivity to ionizing radiation (IAGP)

increased circulating chloride level (IEA)

increased embryonic tissue cell apoptosis (IAGP)

increased lung adenocarcinoma incidence (IAGP)

increased lung adenoma incidence (IAGP)

increased spinal cord apoptosis (IAGP)

no abnormal phenotype detected (IAGP)

oxidative stress (IAGP)

pericardial edema (IAGP)

postnatal growth retardation (IAGP)

premature death (IAGP)

small cerebellum (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Mouse brain organization revealed through direct genome-scale TF expression analysis.	Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3.	MGDs mouse GO annotations	MGD data from the GO Consortium
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:10082581	PMID:10349636	PMID:10506102	PMID:10851089	PMID:10922068	PMID:11042159	PMID:11076861	PMID:11255262	PMID:12466851	PMID:12477932	PMID:12520002
PMID:12819125	PMID:14610273	PMID:15489334	PMID:15601820	PMID:15782199	PMID:16141072	PMID:16141073	PMID:17062627	PMID:17240529	PMID:18258608	PMID:18287559	PMID:18799693
PMID:19037258	PMID:20638939	PMID:21267068	PMID:21677750	PMID:21873635	PMID:22118770	PMID:22405651	PMID:23990909	PMID:24210661	PMID:24213570	PMID:24430184	PMID:24569637
PMID:25622904	PMID:25850934	PMID:26056141	PMID:27543965	PMID:27689697	PMID:29361558	PMID:30269386	PMID:30574150	PMID:32325033	PMID:32554809	PMID:32873638	PMID:33268465
PMID:36543126	PMID:36745565

Genomics

Comparative Map Data

Rnf7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	96,352,990 - 96,360,728 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	96,352,990 - 96,360,728 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	96,470,937 - 96,478,675 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	96,470,937 - 96,478,675 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	96,371,376 - 96,379,014 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	96,280,289 - 96,327,074 (-)	NCBI		MGSCv36	mm8
Celera	9	96,029,356 - 96,036,994 (-)	NCBI		Celera
Cytogenetic Map	9	E3.3	NCBI
cM Map	9	50.63	NCBI

RNF7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	141,738,298 - 141,747,560 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	141,738,249 - 141,747,560 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	141,457,140 - 141,466,402 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	142,939,741 - 142,947,933 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	142,939,748 - 142,947,940	NCBI
Celera	3	139,880,505 - 139,888,693 (+)	NCBI		Celera
Cytogenetic Map	3	q23	NCBI
HuRef	3	138,830,734 - 138,839,328 (+)	NCBI		HuRef
CHM1_1	3	141,420,074 - 141,428,668 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	144,485,514 - 144,494,774 (+)	NCBI		T2T-CHM13v2.0

Rnf7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	105,918,395 - 105,927,643 (-)	NCBI		GRCr8
mRatBN7.2	8	97,038,845 - 97,048,080 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	97,038,840 - 97,047,824 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	102,703,632 - 102,712,543 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	100,902,890 - 100,911,801 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	98,741,847 - 98,750,758 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	104,326,719 - 104,336,098 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	104,326,719 - 104,335,729 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	103,774,031 - 103,783,041 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	101,534,827 - 101,543,837 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	101,554,323 - 101,563,258 (-)	NCBI
Celera	8	96,481,487 - 96,490,405 (-)	NCBI		Celera
Cytogenetic Map	8	q31	NCBI

Rnf7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955508	4,001,441 - 4,003,518 (-)	NCBI	ChiLan1.0	ChiLan1.0

RNF7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	139,649,584 - 139,657,182 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	139,654,420 - 139,661,914 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	138,772,581 - 138,780,763 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	146,369,779 - 146,377,233 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	146,369,779 - 146,377,233 (+)	Ensembl	panpan1.1		panPan2

RNF7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	37,578,222 - 37,584,862 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	37,578,273 - 37,584,523 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	37,569,830 - 37,576,519 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	38,107,894 - 38,114,562 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	38,107,978 - 38,114,846 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	37,791,088 - 37,797,760 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	37,868,181 - 37,874,831 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	38,110,945 - 38,117,638 (+)	NCBI		UU_Cfam_GSD_1.0

Rnf7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	76,744,624 - 76,751,375 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936540	3,484,053 - 3,491,162 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936540	3,484,422 - 3,491,162 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RNF7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	82,548,421 - 82,555,685 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	82,548,475 - 82,554,888 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	90,378,331 - 90,385,390 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RNF7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	48,863,402 - 48,871,321 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	48,860,281 - 48,871,339 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	21,799,141 - 21,806,283 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rnf7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	18,379,682 - 18,390,788 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	18,379,177 - 18,388,505 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Rnf7
234 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	576
Count of miRNA genes:	410
Interacting mature miRNAs:	473
Transcripts:	ENSMUST00000057500, ENSMUST00000071301, ENSMUST00000128955
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4142042	Alpq3_m	alcohol preference QTL 3 (mouse)			Not determined		9	37306197	98701707	Mouse
4141224	Dxmod_m	doxorubicin nephropathy modifier (mouse)			Not determined			49452421	101406120	Mouse
1301241	Renf1_m	renal failure 1 (mouse)			Not determined		9	52034478	99792481	Mouse
13207569	Tcq13_m	total cholesterol QTL 13 (mouse)					9	59897283	109089068	Mouse
4141833	W10q13_m	weight 10 weeks QTL 13 (mouse)			Not determined			63239711	120191934	Mouse
4141545	Tailaq2_m	tail length adjusted QTL 2 (mouse)			Not determined			63239711	120191934	Mouse
1357635	Splq4_m	spleen weight QTL 4 (mouse)			Not determined		9	63239711	120191934	Mouse
1301636	Lith5_m	lithogenic gene 5 (mouse)			Not determined		9	66089077	100089175	Mouse
10045638	Heal29_m	wound healing/regeneration 29 (mouse)			Not determined		9	67006220	101006220	Mouse
1357610	Vtbt8_m	vertebral trabecular bone trait 8 (mouse)			Not determined		9	68779563	102779705	Mouse
1301924	Bmd10_m	bone mineral density 10 (mouse)			Not determined		9	68779563	102779705	Mouse
1301302	Pas4_m	pulmonary adenoma susceptibility 4 (mouse)			Not determined		9	69121898	103121973	Mouse
10412174	Habiir4_m	hyperoxic acute lung injury imprinted region 4 (mouse)			Not determined		9	69267747	98701707	Mouse
1301621	Hpic1_m	haloperidol-induced catalepsy 1 (mouse)			Not determined		9	69428566	103428698	Mouse
1301573	Etohcta8_m	ethanol conditioned taste aversion 8 (mouse)			Not determined		9	72859058	106859205	Mouse
10054068	El8_m	epilepsy 8 (mouse)			Not determined		9	72859058	106859205	Mouse
1301725	Lifespan1_m	life span 1 (mouse)			Not determined		9	74250230	108250378	Mouse
1302065	El1_m	epilepsy 1 (mouse)			Not determined		9	75682646	114303447	Mouse
10054492	El7_m	epilepsy 7 (mouse)			Not determined		9	75682646	114303447	Mouse
1301869	Tbbmd4_m	total body bone mineral density 4 (mouse)			Not determined		9	76024387	101406120	Mouse
1301407	Rapop2_m	radiation-induced apoptosis 2 (mouse)			Not determined		9	76417989	110418183	Mouse
1301192	Skts6_m	skin tumor susceptibility 6 (mouse)			Not determined		9	78522698	112522808	Mouse
10401247	Bglu14_m	blood glucose level 14 (mouse)			Not determined		9	79279863	113279941	Mouse
1301732	Char1_m	P. chabaudi malaria resistance QTL 1 (mouse)			Not determined		9	81680321	115680445	Mouse
10766454	Char10_m	P. chabaudi malaria resistance QTL 10 (mouse)					9	82792386	116792481	Mouse
1300884	Sluc11_m	susceptibility to lung cancer 11 (mouse)			Not determined		9	82792386	116792481	Mouse
1357461	Idd2_m	insulin dependent diabetes susceptibility 2 (mouse)			Not determined		9	82792386	116792481	Mouse
1301487	Nociq1_m	nociceptive sensitivity inflammatory QTL 1 (mouse)			Not determined		9	84406017	118406120	Mouse
10412180	Msam3_m	muscle, skeletal, activity measure 3 (mouse)			Not determined		9	85779563	108518385	Mouse
1300549	Bbaa17_m	B. burgdorferi-associated arthritis 17 (mouse)			Not determined		9	86107600	120107729	Mouse
1302103	Dob2_m	dietary obesity 2 (mouse)			Not determined		9	86121898	120118690	Mouse
11251716	Siim2_m	stress induced immobility 2 (mouse)					9	86625682	120625682	Mouse
12880422	V25Dq6_m	vitamin D inactive form serum level QTL 6 (mouse)					9	87677199	121677199	Mouse
10412242	Alpq8_m	alcohol preference QTL 8 (mouse)			Not determined		9	89162124	123162124	Mouse
1301649	Psl1_m	promotion susceptibility QTL 1 (mouse)			Not determined		9	89289476	123289595	Mouse
18182932	Metl3_m	metabolite locus 3, N-acetylglutamate (mouse)					9	89440541	123440541	Mouse
1357657	Pymr_m	Plasmodium yoelli malaria resistance (mouse)			Not determined		9	89859058	118767089	Mouse
12910770	Splic1_m	spleen iron content 1 (mouse)					9	91291078	124359700	Mouse
12910772	Lvic6_m	liver iron content 6 (mouse)					9	91291078	124359700	Mouse
12910773	Splic3_m	spleen iron content 3 (mouse)					9	91291078	124359700	Mouse
1558767	Skmw11_m	skeletal muscle weight 11 (mouse)			Not determined		9	91518283	124359700	Mouse
13463474	Hbbcq5_m	hemoglobin concentration QTL 5 (mouse)					9	91518283	124359700	Mouse
13463475	Hctq7_m	hematocrit QTL 7 (mouse)					9	91518283	124359700	Mouse
13463477	Rbc9_m	red blood cell count 9 (mouse)					9	91518283	124359700	Mouse
13463478	Mchq18_m	mean corpuscular hemoglobin QTL 18 (mouse)					9	91518283	124359700	Mouse
13463480	Mchcq2_m	mean corpuscular hemoglobin concentration QTL 2 (mouse)					9	91518283	124359700	Mouse
12904937	Edlmmq9_m	extensor digitorum longus muscle mass QTL 9 (mouse)					9	91560372	124359700	Mouse
12904947	Tammq7_m	tibialis anterior muscle mass QTL 7 (mouse)					9	91560372	124359700	Mouse
12904961	Gmmq7_m	gastrocnemius muscle mass QTL 7 (mouse)					9	91560372	124359700	Mouse
1301484	Bwq6_m	body weight (mouse)			Not determined		9	93591658	124359700	Mouse
1302001	Bdln5_m	body length 5 (mouse)			Not determined		9	93591658	124359700	Mouse
14746992	Manh67_m	mandible shape 67 (mouse)					9	93865836	124359700	Mouse
11081166	Psl5_m	promotion susceptibility QTL 5 (mouse)					9	94863354	112701997	Mouse

Markers in Region

UniSTS:236224

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	9	96,503,390 - 96,503,596	UniSTS	GRCm38
MGSCv37	9	96,403,809 - 96,404,015	UniSTS	GRCm37
Celera	9	96,062,466 - 96,062,672	UniSTS
Cytogenetic Map	9	D2.3	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001311135	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_011279	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC161257	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF092877	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK002628	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK003248	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK003963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK006703	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK007588	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK011328	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK146030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK208401	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK209943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC011127	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BF018220	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BY781065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466560	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ231571	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000057500 ⟹ ENSMUSP00000052856

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	9	96,352,990 - 96,360,728 (-)	Ensembl
GRCm38.p6 Ensembl	9	96,470,937 - 96,478,675 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000071301 ⟹ ENSMUSP00000108581

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	9	96,353,816 - 96,360,663 (-)	Ensembl
GRCm38.p6 Ensembl	9	96,471,763 - 96,478,610 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000128955

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	9	96,355,915 - 96,360,641 (-)	Ensembl
GRCm38.p6 Ensembl	9	96,473,862 - 96,478,588 (-)	Ensembl

RefSeq Acc Id:

NM_001311135 ⟹ NP_001298064

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	9	96,352,990 - 96,360,728 (-)	NCBI
GRCm38	9	96,470,937 - 96,478,675 (-)	NCBI

Sequence:

show sequence

GGGAGGCTCCGTGGCGTGTGTTGTGGCCCCGCTGAGCCACCGTACCTCCCGCCTCCGCGCCCAA
CGTCCGCGTCGCCGTTCTGCGCCGCCGCCATGGCCGACGTGGAGGACGGCGAGGAACCCTGCGT
CCTTTCTTCGCACTCCGGGAGCGCAGGCTCCAAGTCGGGAGGCGACAAGATGTTCTCTCTCAAG
AAGTGGAACGCGGTAGCCATGTGGAGCTGGGACGTTGAGTGCGATACCTGTGCCATCTGCAGGG
TCCAGATGCCTGCCTTCGATGTCAAGCTGAAAACAAGCAAGAGGACTGTGTTGTGGTCTGGGGA
GAGTGTAACCATTCCTTCCACAACTGCTGCATGTCCCTGTGGGTGAAACAGAACAATCGCTGCC
CTCTGTGCCAGCAGGACTGGGTAGTCCAAAGAATCGGCAAATGAGAGGTGGCCCAGGCGCTCCT
GGTGTGGTTGCTGACCCTGGACAAAGACTAAACACTGCAGGGGATTCATCCTTGAGAGAGAGAG
GATGCTGTGCGCCTTTGAGACTCACCAAAGGCTTGCTTTATTAATTTGTCTGTTTAGTTTTGGG
AAATTCTCTACAATTAAGATAATTTGTTAAAAATGGCCTTTCCTACCTCTGGTGTGTGTGTGTG
ATACGAATGCATAGAAGAGCGAGAACACCAGAAAATGATCTTTGTTTATCTGTACCCACGACTG
TGGGAACATTGTGTTCACAGAAGAACATTGTTTGTGTTTATGCTTGAGGGTTAAAAAATAGATA
AACGAATGTTACAGTAACAAATAAAATGCATTGAAAAGCCGACTCCTCCTAATCCTTTTTGTGT
TGGGAGAGAGGCAAGCGAGGCCACCCTGCTGTCTTCATTTGCTGTGAATGAGGATTTTAACCTG
CACTCAGTGAAGAGGCGTAACTGTCGGGTAAACTGTAATATGGCGTAACTGTCGGGTAAACGGC
TTTGTCTCCTGACTTCTCCATCTTTGACTTGGCCAGGAAGCCTGGATTGTTCAACCACTTAGTT
CTAAAGAACTGTTTTCTGTTTTTGCGAAGGTTGTATTGTATGTTTTAGTCAAAATATTAGTAGG
AAAATGCTTACTAGTATAACACTGAAGTTCATTATGCAATGTTTTAATAAAATATTGTGCTTTG
AGTTATTAAAGTTTGATATATACTCTTAAAATCATTAAACTAATTCATCAATTAAATAATTTGA
AAAAATTAA

hide sequence

RefSeq Acc Id:

NM_011279 ⟹ NP_035409

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	9	96,352,990 - 96,360,728 (-)	NCBI
GRCm38	9	96,470,937 - 96,478,675 (-)	NCBI
MGSCv37	9	96,371,376 - 96,379,014 (-)	RGD
Celera	9	96,029,356 - 96,036,994 (-)	RGD
cM Map	9		ENTREZGENE

Sequence:

show sequence

GGGAGGCTCCGTGGCGTGTGTTGTGGCCCCGCTGAGCCACCGTACCTCCCGCCTCCGCGCCCAA
CGTCCGCGTCGCCGTTCTGCGCCGCCGCCATGGCCGACGTGGAGGACGGCGAGGAACCCTGCGT
CCTTTCTTCGCACTCCGGGAGCGCAGGCTCCAAGTCGGGAGGCGACAAGATGTTCTCTCTCAAG
AAGTGGAACGCGGTAGCCATGTGGAGCTGGGACGTTGAGTGCGATACCTGTGCCATCTGCAGGG
TCCAGGTGATGGATGCCTGCCTTCGATGTCAAGCTGAAAACAAGCAAGAGGACTGTGTTGTGGT
CTGGGGAGAGTGTAACCATTCCTTCCACAACTGCTGCATGTCCCTGTGGGTGAAACAGAACAAT
CGCTGCCCTCTGTGCCAGCAGGACTGGGTAGTCCAAAGAATCGGCAAATGAGAGGTGGCCCAGG
CGCTCCTGGTGTGGTTGCTGACCCTGGACAAAGACTAAACACTGCAGGGGATTCATCCTTGAGA
GAGAGAGGATGCTGTGCGCCTTTGAGACTCACCAAAGGCTTGCTTTATTAATTTGTCTGTTTAG
TTTTGGGAAATTCTCTACAATTAAGATAATTTGTTAAAAATGGCCTTTCCTACCTCTGGTGTGT
GTGTGTGATACGAATGCATAGAAGAGCGAGAACACCAGAAAATGATCTTTGTTTATCTGTACCC
ACGACTGTGGGAACATTGTGTTCACAGAAGAACATTGTTTGTGTTTATGCTTGAGGGTTAAAAA
ATAGATAAACGAATGTTACAGTAACAAATAAAATGCATTGAAAAGCCGACTCCTCCTAATCCTT
TTTGTGTTGGGAGAGAGGCAAGCGAGGCCACCCTGCTGTCTTCATTTGCTGTGAATGAGGATTT
TAACCTGCACTCAGTGAAGAGGCGTAACTGTCGGGTAAACTGTAATATGGCGTAACTGTCGGGT
AAACGGCTTTGTCTCCTGACTTCTCCATCTTTGACTTGGCCAGGAAGCCTGGATTGTTCAACCA
CTTAGTTCTAAAGAACTGTTTTCTGTTTTTGCGAAGGTTGTATTGTATGTTTTAGTCAAAATAT
TAGTAGGAAAATGCTTACTAGTATAACACTGAAGTTCATTATGCAATGTTTTAATAAAATATTG
TGCTTTGAGTTATTAAAGTTTGATATATACTCTTAAAATCATTAAACTAATTCATCAATTAAAT
AATTTGAAAAAATTAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001298064	(Get FASTA)	NCBI Sequence Viewer
	NP_035409	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD25961	(Get FASTA)	NCBI Sequence Viewer
	AAH11127	(Get FASTA)	NCBI Sequence Viewer
	BAB22666	(Get FASTA)	NCBI Sequence Viewer
	BAE26843	(Get FASTA)	NCBI Sequence Viewer
	EDL20955	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000052856
	ENSMUSP00000052856.5
	ENSMUSP00000108581
	ENSMUSP00000108581.2
GenBank Protein	Q9WTZ1	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_035409 ⟸ NM_011279
- Peptide Label:	isoform 1
- UniProtKB:	Q3UKF8 (UniProtKB/Swiss-Prot), Q9WTZ1 (UniProtKB/Swiss-Prot), D3Z497 (UniProtKB/TrEMBL)
- Sequence:	show sequence MADVEDGEEPCVLSSHSGSAGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDACLRC QAENKQEDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIGK hide sequence

RefSeq Acc Id:	NP_001298064 ⟸ NM_001311135
- Peptide Label:	isoform 2
- UniProtKB:	D3Z392 (UniProtKB/TrEMBL)
- Sequence:	show sequence MADVEDGEEPCVLSSHSGSAGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQMPAFDVKL KTSKRTVLWSGESVTIPSTTAACPCG hide sequence

RefSeq Acc Id:

ENSMUSP00000108581 ⟸ ENSMUST00000071301

RefSeq Acc Id:

ENSMUSP00000052856 ⟸ ENSMUST00000057500

Protein Domains

Anaphase-promoting complex subunit 11 RING-H2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9WTZ1-F1-model_v2	AlphaFold	Q9WTZ1	1-113	view protein structure

Promoters

RGD ID:

6845049

Promoter ID:

MM_KWN:58420

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

ENSMUST00000071301, OTTMUST00000055285, OTTMUST00000055287

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	9	96,378,861 - 96,379,361 (-)	MPROMDB

RGD ID:

8670494

Promoter ID:

EPDNEW_M13278

Type:

initiation region

Name:

Rnf7_1

Description:

Mus musculus ring finger protein 7 , transcript variant 1, mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	9	96,478,598 - 96,478,658	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1337096	AgrOrtholog
Ensembl Genes	ENSMUSG00000051234	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000057500	ENTREZGENE
	ENSMUST00000057500.6	UniProtKB/Swiss-Prot
	ENSMUST00000071301	ENTREZGENE
	ENSMUST00000071301.5	UniProtKB/TrEMBL
Gene3D-CATH	3.30.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Apc11	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/Swiss-Prot
	Znf_RING/FYVE/PHD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING_H2	UniProtKB/Swiss-Prot
KEGG Report	mmu:19823	UniProtKB/Swiss-Prot
MGD	MGI:1337096	ENTREZGENE
NCBI Gene	19823	ENTREZGENE
PANTHER	RING BOX	UniProtKB/Swiss-Prot
	RING-BOX PROTEIN 2	UniProtKB/Swiss-Prot
Pfam	zf-ANAPC11	UniProtKB/TrEMBL
	zf-rbx1	UniProtKB/Swiss-Prot
PhenoGen	Rnf7	PhenoGen
PROSITE	ZF_RING_2	UniProtKB/Swiss-Prot
Superfamily-SCOP	RING/U-box	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	D3Z392	ENTREZGENE, UniProtKB/TrEMBL
	D3Z497	ENTREZGENE
	Q3UKF8	ENTREZGENE
	Q9WTZ1	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q3UKF8	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

Mammalian Phenotype