Rnf7 (ring finger protein 7) - Rat Genome Database

Name: Rnf7
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Rnf7 (ring finger protein 7) Mus musculus

Analyze

Symbol:

Rnf7

Name:

ring finger protein 7

RGD ID:

1322299

MGI Page

MGI

Description:

Predicted to have NEDD8 ligase activity; cullin family protein binding activity; and ubiquitin protein ligase activity. Involved in several processes, including brain development; intrinsic apoptotic signaling pathway in response to oxidative stress; and regulation of apoptotic process. Localizes to cytoplasm and nucleus. Is expressed in brain; eye; and genitourinary system. Orthologous to human RNF7 (ring finger protein 7); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

Rbx; Rbx2; RING-box protein 2; S; SAG; sensitive to apoptosis gene protein

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RNF7 (ring finger protein 7)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Rnf7 (ring finger protein 7)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Rnf7 (ring finger protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RNF7 (ring finger protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RNF7 (ring finger protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rnf7 (ring finger protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RNF7 (ring finger protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	RNF7 (ring finger protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rnf7 (ring finger protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	RBX1 (ring-box 1)	HGNC	OrthoDB
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Rnf7 (ring finger protein 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Homo sapiens (human):	RNF7 (ring finger protein 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Danio rerio (zebrafish):	rnf7 (ring finger protein 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Saccharomyces cerevisiae (baker's yeast):	HRT1	Alliance	DIOPT (OMA\|PANTHER\|Roundup)
Drosophila melanogaster (fruit fly):	Roc2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Caenorhabditis elegans (roundworm):	rbx-2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)

Related Pseudogenes:

Gm35144 Gm7075

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	96,352,990 - 96,360,728 (-)	NCBI	GRCm39		mm39
GRCm38	9	96,470,937 - 96,478,675 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	96,470,937 - 96,478,675 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	96,371,376 - 96,379,014 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	9	96,280,289 - 96,327,074 (-)	NCBI			mm8
Celera	9	96,029,356 - 96,036,994 (-)	NCBI		Celera
Cytogenetic Map	9	E3.3	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP)

2-hydroxypropanoic acid (ISO)

6-propyl-2-thiouracil (ISO)

all-trans-retinoic acid (EXP,ISO)

arsane (ISO)

arsenic atom (ISO)

bisphenol A (ISO)

chromium(6+) (EXP)

clofibrate (EXP)

cobalt dichloride (ISO)

cyclosporin A (ISO)

dieldrin (ISO)

doxorubicin (ISO)

enzyme inhibitor (ISO)

ethanol (EXP)

flutamide (ISO)

folic acid (EXP)

glafenine (ISO)

lead(0) (ISO)

lead(2+) (ISO)

methimazole (ISO)

methyl methanesulfonate (ISO)

miconazole (EXP)

N-methyl-4-phenylpyridinium (ISO)

nefazodone (ISO)

nimesulide (ISO)

paracetamol (ISO)

pirinixic acid (EXP)

rac-lactic acid (ISO)

reactive oxygen species (ISO)

sodium arsenite (ISO)

tamoxifen (EXP)

tetrachloromethane (EXP)

tolcapone (ISO)

tungsten (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

activation of cysteine-type endopeptidase activity involved in apoptotic process (IDA)

apoptotic mitochondrial changes (IDA)

cerebral cortex radially oriented cell migration (IGI,IMP)

intrinsic apoptotic signaling pathway in response to oxidative stress (IDA)

negative regulation of apoptotic process (IDA)

protein neddylation (ISO)

protein ubiquitination (IBA)

radial glia guided migration of Purkinje cell (IGI,IMP)

ubiquitin-dependent protein catabolic process (IBA)

Cellular Component

Cul5-RING ubiquitin ligase complex (IBA,ISO)

cullin-RING ubiquitin ligase complex (IBA)

cytoplasm (IDA)

cytosol (ISO)

nucleoplasm (ISO)

nucleus (IBA,IDA)

Molecular Function

cullin family protein binding (IBA,ISO)

metal ion binding (IEA)

NEDD8 ligase activity (ISO)

protein binding (IPI)

ubiquitin protein ligase activity (IBA)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

ubiquitin/proteasome degradation pathway (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal angiogenesis (IAGP)

abnormal cell cycle (IAGP)

abnormal cell differentiation (IAGP)

abnormal cerebellar layer morphology (IAGP)

abnormal cerebellum development (IAGP)

abnormal cortical marginal zone morphology (IAGP)

abnormal cortical plate morphology (IAGP)

abnormal neuronal migration (IAGP)

abnormal response to tactile stimuli (IEA)

abnormal visceral yolk sac blood island morphology (IAGP)

abnormal vitelline vasculature morphology (IAGP)

decreased angiogenesis (IAGP)

decreased cell proliferation (IAGP)

decreased cerebellar granule cell precursor proliferation (IAGP)

decreased circulating chloride level (IEA)

decreased circulating triglyceride level (IEA)

decreased lung tumor incidence (IAGP)

delaminated Purkinje cell layer (IAGP)

ectopic Purkinje cell (IAGP)

embryonic growth retardation (IAGP)

embryonic lethality during organogenesis, complete penetrance (IAGP)

enlarged brain ventricles (IAGP)

hydrocephaly (IAGP)

increased apoptosis (IAGP)

increased cellular sensitivity to ionizing radiation (IAGP)

increased circulating chloride level (IEA)

increased embryonic tissue cell apoptosis (IAGP)

increased lung adenocarcinoma incidence (IAGP)

increased lung adenoma incidence (IAGP)

increased spinal cord apoptosis (IAGP)

no abnormal phenotype detected (IAGP)

oxidative stress (IAGP)

pericardial edema (IAGP)

postnatal growth retardation (IAGP)

premature death (IAGP)

small cerebellum (IAGP)

References

References - curated


1.	Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3.	MGD data from the GO Consortium
4.	Pipeline to import KEGG annotations from KEGG into RGD
5.	RGD automated import pipeline
6.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:10082581	PMID:10349636	PMID:10506102	PMID:10851089	PMID:10922068	PMID:11042159	PMID:11076861	PMID:11255262	PMID:12466851	PMID:12477932	PMID:12520002
PMID:12819125	PMID:14610273	PMID:15489334	PMID:15601820	PMID:15782199	PMID:16141072	PMID:16141073	PMID:17062627	PMID:17240529	PMID:18258608	PMID:18287559	PMID:18799693
PMID:19037258	PMID:20638939	PMID:21267068	PMID:21677750	PMID:21873635	PMID:22118770	PMID:22405651	PMID:23990909	PMID:24210661	PMID:24213570	PMID:24430184	PMID:24569637
PMID:25622904	PMID:25850934	PMID:26056141	PMID:27543965	PMID:27689697	PMID:29361558	PMID:30269386	PMID:30574150	PMID:32325033

Genomics

Comparative Map Data

Rnf7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	96,352,990 - 96,360,728 (-)	NCBI	GRCm39		mm39
GRCm38	9	96,470,937 - 96,478,675 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	96,470,937 - 96,478,675 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	96,371,376 - 96,379,014 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	9	96,280,289 - 96,327,074 (-)	NCBI			mm8
Celera	9	96,029,356 - 96,036,994 (-)	NCBI		Celera
Cytogenetic Map	9	E3.3	NCBI

RNF7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	3	141,738,249 - 141,747,560 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	3	141,738,298 - 141,747,560 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	3	141,457,051 - 141,465,645 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	142,939,741 - 142,947,933 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	3	142,939,748 - 142,947,940	NCBI
Celera	3	139,880,505 - 139,888,693 (+)	NCBI
Cytogenetic Map	3	q23	NCBI
HuRef	3	138,830,734 - 138,839,328 (+)	NCBI		HuRef
CHM1_1	3	141,420,074 - 141,428,668 (+)	NCBI		CHM1_1

Rnf7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	8	104,326,719 - 104,336,098 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	104,326,719 - 104,335,729 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	103,774,031 - 103,783,041 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	101,534,827 - 101,543,837 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	8	101,554,323 - 101,563,258 (-)	NCBI
Celera	8	96,481,487 - 96,490,405 (-)	NCBI		Celera
Cytogenetic Map	8	q31	NCBI

Rnf7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955508	4,001,441 - 4,003,518 (-)	NCBI	ChiLan1.0	ChiLan1.0

RNF7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	3	146,369,779 - 146,377,233 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	146,369,779 - 146,377,233 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	3	138,772,581 - 138,780,763 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

RNF7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	23	37,578,273 - 37,584,523 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	23	37,578,222 - 37,584,862 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Rnf7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936540	3,484,422 - 3,491,162 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RNF7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	82,548,548 - 82,555,685 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	82,548,475 - 82,554,888 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	90,378,331 - 90,385,390 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RNF7
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	48,863,402 - 48,871,321 (-)	NCBI
ChlSab1.1 Ensembl	15	48,860,281 - 48,871,339 (-)	Ensembl

Rnf7
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624730	18,379,177 - 18,388,505 (+)	NCBI

Position Markers

UniSTS:236224

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	9	96,503,390 - 96,503,596	UniSTS	GRCm38
MGSCv37	9	96,403,809 - 96,404,015	UniSTS	GRCm37
Celera	9	96,062,466 - 96,062,672	UniSTS
Cytogenetic Map	9	D2.3	UniSTS

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4142042	Alpq3_m	alcohol preference QTL 3 (mouse)			Not determined		9	37394901	98819654	Mouse
4141224	Dxmod_m	doxorubicin nephropathy modifier (mouse)			Not determined			49541121	101528921	Mouse
1301241	Renf1_m	renal failure 1 (mouse)			Not determined		9	52123178	99910428	Mouse
13207569	Tcq13_m	total cholesterol QTL 13 (mouse)					9	59990000	109260000	Mouse
4141833	W10q13_m	weight 10 weeks QTL 13 (mouse)			Not determined			63332429	120362868	Mouse
4141545	Tailaq2_m	tail length adjusted QTL 2 (mouse)			Not determined			63332429	120362868	Mouse
1357635	Splq4_m	spleen weight QTL 4 (mouse)			Not determined		9	63332429	120362868	Mouse
1301636	Lith5_m	lithogenic gene 5 (mouse)			Not determined		9	66207024	100207122	Mouse
10045638	Heal29_m	wound healing/regeneration 29 (mouse)			Not determined		9	67124167	101124167	Mouse
1357610	Vtbt8_m	vertebral trabecular bone trait 8 (mouse)			Not determined		9	68897510	102897652	Mouse
1301924	Bmd10_m	bone mineral density 10 (mouse)			Not determined		9	68897510	102897652	Mouse
1301302	Pas4_m	pulmonary adenoma susceptibility 4 (mouse)			Not determined		9	69239845	103239920	Mouse
10412174	Habiir4_m	hyperoxic acute lung injury imprinted region 4 (mouse)			Not determined		9	69360465	98819654	Mouse
1301621	Hpic1_m	haloperidol-induced catalepsy 1 (mouse)			Not determined		9	69546513	103546645	Mouse
1301573	Etohcta8_m	ethanol conditioned taste aversion 8 (mouse)			Not determined		9	72977005	106977152	Mouse
10054068	El8_m	epilepsy 8 (mouse)			Not determined		9	72977005	106977152	Mouse
1301725	Lifespan1_m	life span 1 (mouse)			Not determined		9	74368177	108368325	Mouse
1302065	El1_m	epilepsy 1 (mouse)			Not determined		9	75775364	114474379	Mouse
10054492	El7_m	epilepsy 7 (mouse)			Not determined		9	75775364	114474379	Mouse
1301869	Tbbmd4_m	total body bone mineral density 4 (mouse)			Not determined		9	76117105	101528921	Mouse
1301407	Rapop2_m	radiation-induced apoptosis 2 (mouse)			Not determined		9	76535936	110536130	Mouse
1301192	Skts6_m	skin tumor susceptibility 6 (mouse)			Not determined		9	78640645	112640755	Mouse
10401247	Bglu14_m	blood glucose level 14 (mouse)			Not determined		9	79397810	113397888	Mouse
1301732	Char1_m	P. chabaudi malaria resistance QTL 1 (mouse)			Not determined		9	81798268	115798392	Mouse
1300884	Sluc11_m	susceptibility to lung cancer 11 (mouse)			Not determined		9	82910333	116910428	Mouse
1357461	Idd2_m	insulin dependent diabetes susceptibility 2 (mouse)			Not determined		9	82910333	116910428	Mouse
10766454	Char10_m	P. chabaudi malaria resistance QTL 10 (mouse)					9	82910333	116910428	Mouse
1301487	Nociq1_m	nociceptive sensitivity inflammatory QTL 1 (mouse)			Not determined		9	84528818	118528921	Mouse
10412180	Msam3_m	muscle, skeletal, activity measure 3 (mouse)			Not determined		9	85897510	108641186	Mouse
1300549	Bbaa17_m	B. burgdorferi-associated arthritis 17 (mouse)			Not determined		9	86230401	120230530	Mouse
1302103	Dob2_m	dietary obesity 2 (mouse)			Not determined		9	86239845	120289624	Mouse
11251716	Siim2_m	stress induced immobility 2 (mouse)					9	86748483	120748483	Mouse
12880422	V25Dq6_m	vitamin D inactive form serum level QTL 6 (mouse)					9	87800000	121800000	Mouse
10412242	Alpq8_m	alcohol preference QTL 8 (mouse)			Not determined		9	89284925	123284925	Mouse
1301649	Psl1_m	promotion susceptibility QTL 1 (mouse)			Not determined		9	89412277	123412396	Mouse
18182932	Metl3_m	metabolite locus 3, N-acetylglutamate (mouse)					9	89563342	123563342	Mouse
1357657	Pymr_m	Plasmodium yoelli malaria resistance (mouse)			Not determined		9	89977005	118938021	Mouse
12910770	Splic1_m	spleen iron content 1 (mouse)					9	91413879	124595110	Mouse
12910772	Lvic6_m	liver iron content 6 (mouse)					9	91413879	124595110	Mouse
12910773	Splic3_m	spleen iron content 3 (mouse)					9	91413879	124595110	Mouse
1558767	Skmw11_m	skeletal muscle weight 11 (mouse)			Not determined		9	91641084	124595110	Mouse
13463474	Hbbcq5_m	hemoglobin concentration QTL 5 (mouse)					9	91641084	124595110	Mouse
13463475	Hctq7_m	hematocrit QTL 7 (mouse)					9	91641084	124595110	Mouse
13463477	Rbc9_m	red blood cell count 9 (mouse)					9	91641084	124595110	Mouse
13463478	Mchq18_m	mean corpuscular hemoglobin QTL 18 (mouse)					9	91641084	124595110	Mouse
13463480	Mchcq2_m	mean corpuscular hemoglobin concentration QTL 2 (mouse)					9	91641084	124595110	Mouse
12904937	Edlmmq9_m	extensor digitorum longus muscle mass QTL 9 (mouse)					9	91683173	124595110	Mouse
12904947	Tammq7_m	tibialis anterior muscle mass QTL 7 (mouse)					9	91683173	124595110	Mouse
12904961	Gmmq7_m	gastrocnemius muscle mass QTL 7 (mouse)					9	91683173	124595110	Mouse
1302001	Bdln5_m	body length 5 (mouse)			Not determined		9	93762590	124595110	Mouse
1301484	Bwq6_m	body weight (mouse)			Not determined		9	93762590	124595110	Mouse
14746992	Manh67_m	mandible shape 67 (mouse)					9	94036768	124595110	Mouse
11081166	Psl5_m	promotion susceptibility QTL 5 (mouse)					9	94981301	112872929	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	576
Count of miRNA genes:	410
Interacting mature miRNAs:	473
Transcripts:	ENSMUST00000057500, ENSMUST00000071301, ENSMUST00000128955
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001311135	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_011279	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC161257	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF092877	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK002628	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK003248	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK003963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK006703	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK007588	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK011328	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK146030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK208401	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK209943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC011127	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BF018220	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BY781065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466560	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ231571	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000057500 ⟹ ENSMUSP00000052856

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	9	96,470,937 - 96,478,675 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000071301 ⟹ ENSMUSP00000108581

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	9	96,471,763 - 96,478,610 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000128955

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	9	96,473,862 - 96,478,588 (-)	Ensembl

RefSeq Acc Id:

NM_001311135 ⟹ NP_001298064

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	9	96,352,990 - 96,360,728 (-)	NCBI
GRCm38	9	96,470,937 - 96,478,675 (-)	NCBI

Sequence:

show sequence

GGGAGGCTCCGTGGCGTGTGTTGTGGCCCCGCTGAGCCACCGTACCTCCCGCCTCCGCGCCCAA
CGTCCGCGTCGCCGTTCTGCGCCGCCGCCATGGCCGACGTGGAGGACGGCGAGGAACCCTGCGT
CCTTTCTTCGCACTCCGGGAGCGCAGGCTCCAAGTCGGGAGGCGACAAGATGTTCTCTCTCAAG
AAGTGGAACGCGGTAGCCATGTGGAGCTGGGACGTTGAGTGCGATACCTGTGCCATCTGCAGGG
TCCAGATGCCTGCCTTCGATGTCAAGCTGAAAACAAGCAAGAGGACTGTGTTGTGGTCTGGGGA
GAGTGTAACCATTCCTTCCACAACTGCTGCATGTCCCTGTGGGTGAAACAGAACAATCGCTGCC
CTCTGTGCCAGCAGGACTGGGTAGTCCAAAGAATCGGCAAATGAGAGGTGGCCCAGGCGCTCCT
GGTGTGGTTGCTGACCCTGGACAAAGACTAAACACTGCAGGGGATTCATCCTTGAGAGAGAGAG
GATGCTGTGCGCCTTTGAGACTCACCAAAGGCTTGCTTTATTAATTTGTCTGTTTAGTTTTGGG
AAATTCTCTACAATTAAGATAATTTGTTAAAAATGGCCTTTCCTACCTCTGGTGTGTGTGTGTG
ATACGAATGCATAGAAGAGCGAGAACACCAGAAAATGATCTTTGTTTATCTGTACCCACGACTG
TGGGAACATTGTGTTCACAGAAGAACATTGTTTGTGTTTATGCTTGAGGGTTAAAAAATAGATA
AACGAATGTTACAGTAACAAATAAAATGCATTGAAAAGCCGACTCCTCCTAATCCTTTTTGTGT
TGGGAGAGAGGCAAGCGAGGCCACCCTGCTGTCTTCATTTGCTGTGAATGAGGATTTTAACCTG
CACTCAGTGAAGAGGCGTAACTGTCGGGTAAACTGTAATATGGCGTAACTGTCGGGTAAACGGC
TTTGTCTCCTGACTTCTCCATCTTTGACTTGGCCAGGAAGCCTGGATTGTTCAACCACTTAGTT
CTAAAGAACTGTTTTCTGTTTTTGCGAAGGTTGTATTGTATGTTTTAGTCAAAATATTAGTAGG
AAAATGCTTACTAGTATAACACTGAAGTTCATTATGCAATGTTTTAATAAAATATTGTGCTTTG
AGTTATTAAAGTTTGATATATACTCTTAAAATCATTAAACTAATTCATCAATTAAATAATTTGA
AAAAATTAA

hide sequence

RefSeq Acc Id:

NM_011279 ⟹ NP_035409

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	9	96,352,990 - 96,360,728 (-)	NCBI
GRCm38	9	96,470,937 - 96,478,675 (-)	NCBI
MGSCv37	9	96,371,376 - 96,379,014 (-)	RGD
Celera	9	96,029,356 - 96,036,994 (-)	RGD
cM Map	9		ENTREZGENE

Sequence:

show sequence

GGGAGGCTCCGTGGCGTGTGTTGTGGCCCCGCTGAGCCACCGTACCTCCCGCCTCCGCGCCCAA
CGTCCGCGTCGCCGTTCTGCGCCGCCGCCATGGCCGACGTGGAGGACGGCGAGGAACCCTGCGT
CCTTTCTTCGCACTCCGGGAGCGCAGGCTCCAAGTCGGGAGGCGACAAGATGTTCTCTCTCAAG
AAGTGGAACGCGGTAGCCATGTGGAGCTGGGACGTTGAGTGCGATACCTGTGCCATCTGCAGGG
TCCAGGTGATGGATGCCTGCCTTCGATGTCAAGCTGAAAACAAGCAAGAGGACTGTGTTGTGGT
CTGGGGAGAGTGTAACCATTCCTTCCACAACTGCTGCATGTCCCTGTGGGTGAAACAGAACAAT
CGCTGCCCTCTGTGCCAGCAGGACTGGGTAGTCCAAAGAATCGGCAAATGAGAGGTGGCCCAGG
CGCTCCTGGTGTGGTTGCTGACCCTGGACAAAGACTAAACACTGCAGGGGATTCATCCTTGAGA
GAGAGAGGATGCTGTGCGCCTTTGAGACTCACCAAAGGCTTGCTTTATTAATTTGTCTGTTTAG
TTTTGGGAAATTCTCTACAATTAAGATAATTTGTTAAAAATGGCCTTTCCTACCTCTGGTGTGT
GTGTGTGATACGAATGCATAGAAGAGCGAGAACACCAGAAAATGATCTTTGTTTATCTGTACCC
ACGACTGTGGGAACATTGTGTTCACAGAAGAACATTGTTTGTGTTTATGCTTGAGGGTTAAAAA
ATAGATAAACGAATGTTACAGTAACAAATAAAATGCATTGAAAAGCCGACTCCTCCTAATCCTT
TTTGTGTTGGGAGAGAGGCAAGCGAGGCCACCCTGCTGTCTTCATTTGCTGTGAATGAGGATTT
TAACCTGCACTCAGTGAAGAGGCGTAACTGTCGGGTAAACTGTAATATGGCGTAACTGTCGGGT
AAACGGCTTTGTCTCCTGACTTCTCCATCTTTGACTTGGCCAGGAAGCCTGGATTGTTCAACCA
CTTAGTTCTAAAGAACTGTTTTCTGTTTTTGCGAAGGTTGTATTGTATGTTTTAGTCAAAATAT
TAGTAGGAAAATGCTTACTAGTATAACACTGAAGTTCATTATGCAATGTTTTAATAAAATATTG
TGCTTTGAGTTATTAAAGTTTGATATATACTCTTAAAATCATTAAACTAATTCATCAATTAAAT
AATTTGAAAAAATTAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001298064	(Get FASTA)	NCBI Sequence Viewer
	NP_035409	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD25961	(Get FASTA)	NCBI Sequence Viewer
	AAH11127	(Get FASTA)	NCBI Sequence Viewer
	BAB22666	(Get FASTA)	NCBI Sequence Viewer
	BAE26843	(Get FASTA)	NCBI Sequence Viewer
	EDL20955	(Get FASTA)	NCBI Sequence Viewer
	Q9WTZ1	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_035409 ⟸ NM_011279
- Peptide Label:	isoform 1
- UniProtKB:	Q9WTZ1 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MADVEDGEEPCVLSSHSGSAGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDACLRC QAENKQEDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIGK hide sequence

RefSeq Acc Id:	NP_001298064 ⟸ NM_001311135
- Peptide Label:	isoform 2
- UniProtKB:	Q9WTZ1 (UniProtKB/Swiss-Prot), D3Z392 (UniProtKB/TrEMBL)
- Sequence:	show sequence MADVEDGEEPCVLSSHSGSAGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQMPAFDVKL KTSKRTVLWSGESVTIPSTTAACPCG hide sequence

RefSeq Acc Id:

ENSMUSP00000108581 ⟸ ENSMUST00000071301

RefSeq Acc Id:

ENSMUSP00000052856 ⟸ ENSMUST00000057500

Protein Domains

zf-ANAPC11

Promoters

RGD ID:

6845049

Promoter ID:

MM_KWN:58420

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

ENSMUST00000071301, OTTMUST00000055285, OTTMUST00000055287

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	9	96,378,861 - 96,379,361 (-)	MPROMDB

RGD ID:

8670494

Promoter ID:

EPDNEW_M13278

Type:

initiation region

Name:

Rnf7_1

Description:

Mus musculus ring finger protein 7 , transcript variant 1, mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	9	96,478,598 - 96,478,658	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1337096	AgrOrtholog
Ensembl Genes	ENSMUSG00000051234	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000052856	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUSP00000108581	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000057500	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUST00000071301	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	3.30.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Apc11	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/Swiss-Prot
	Znf_RING/FYVE/PHD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING_H2	UniProtKB/Swiss-Prot
KEGG Report	mmu:19823	UniProtKB/Swiss-Prot
MGD	MGI:1337096	ENTREZGENE
NCBI Gene	19823	ENTREZGENE
Pfam	zf-ANAPC11	UniProtKB/TrEMBL
	zf-rbx1	UniProtKB/Swiss-Prot
PhenoGen	Rnf7	PhenoGen
PROSITE	ZF_RING_2	UniProtKB/Swiss-Prot
UniGene	Mm.28235	ENTREZGENE
UniProt	D3Z392	ENTREZGENE, UniProtKB/TrEMBL
	Q9WTZ1	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q3UKF8	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Annotations - KEGG (archival)