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Gene: Adsl (adenylosuccinate lyase) Mus musculus
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Symbol: Adsl
Name: adenylosuccinate lyase
Description: Predicted to have (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity and N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity. Predicted to be involved in several processes, including 'de novo' AMP biosynthetic process; aerobic respiration; and protein tetramerization. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in adenylosuccinase lyase deficiency. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human ADSL (adenylosuccinate lyase).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: adenylosuccinase; adenylosuccinate lyase 1; Adl; ASase; Asl
Orthologs:
Homo sapiens (human) : ADSL (adenylosuccinate lyase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Adsl (adenylosuccinate lyase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adsl (adenylosuccinate lyase)
Pan paniscus (bonobo/pygmy chimpanzee) : ADSL (adenylosuccinate lyase)
Canis lupus familiaris (dog) : ADSL (adenylosuccinate lyase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adsl (adenylosuccinate lyase)
Sus scrofa (pig) : ADSL (adenylosuccinate lyase)
more info ...
Related Pseudogenes: Gm18108  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381580,948,490 - 80,970,947 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371580,778,949 - 80,799,803 (+)NCBIGRCm37mm9NCBIm37
MGSCv361580,775,774 - 80,796,628 (+)NCBImm8
Celera1583,068,973 - 83,091,236 (+)NCBICelera
Cytogenetic Map15 E1NCBI
cM Map1537.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Adsl
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316917
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.