Tnk1 (tyrosine kinase, non-receptor, 1) - Rat Genome Database

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Gene: Tnk1 (tyrosine kinase, non-receptor, 1) Mus musculus
Analyze
Symbol: Tnk1
Name: tyrosine kinase, non-receptor, 1
RGD ID: 1320829
MGI Page MGI
Description: Enables ATP binding activity and non-membrane spanning protein tyrosine kinase activity. Involved in negative regulation of Ras protein signal transduction and negative regulation of cell growth. Located in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; pituitary gland; respiratory system; and thymus. Orthologous to human TNK1 (tyrosine kinase non receptor 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: kinase of embryonic stem cells; Ko; Kos1; non-receptor tyrosine kinase; non-receptor tyrosine-protein kinase TNK1; Tnk; Tnk1a; Tnk1b
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,741,389 - 69,749,556 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,741,831 - 69,749,556 (-)EnsemblGRCm39 Ensembl
GRCm381169,850,563 - 69,858,730 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,851,005 - 69,858,730 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,664,065 - 69,672,232 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361170,435,206 - 70,442,824 (-)NCBIMGSCv36mm8
MGSCv361169,667,294 - 69,674,912 (-)NCBIMGSCv36mm8
Cytogenetic Map11B3NCBI
cM Map1142.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
cytosol  (IDA)
membrane  (ISO)
plasma membrane  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11114734   PMID:11217851   PMID:12477932   PMID:12789265   PMID:15489334   PMID:16141072   PMID:16141073  
PMID:16602821   PMID:18287559   PMID:18554416   PMID:18974114   PMID:19481140   PMID:21873635   PMID:24194600   PMID:24449862   PMID:25758223   PMID:30320600   PMID:32694928  


Genomics

Comparative Map Data
Tnk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,741,389 - 69,749,556 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,741,831 - 69,749,556 (-)EnsemblGRCm39 Ensembl
GRCm381169,850,563 - 69,858,730 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,851,005 - 69,858,730 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,664,065 - 69,672,232 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361170,435,206 - 70,442,824 (-)NCBIMGSCv36mm8
MGSCv361169,667,294 - 69,674,912 (-)NCBIMGSCv36mm8
Cytogenetic Map11B3NCBI
cM Map1142.9NCBI
TNK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,380,047 - 7,389,742 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,380,534 - 7,389,774 (+)EnsemblGRCh38hg38GRCh38
GRCh37177,284,408 - 7,293,061 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,225,089 - 7,233,816 (+)NCBINCBI36Build 36hg18NCBI36
Build 34177,225,133 - 7,233,780NCBI
Celera177,310,277 - 7,319,007 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,178,337 - 7,187,140 (+)NCBIHuRef
CHM1_1177,293,383 - 7,302,185 (+)NCBICHM1_1
T2T-CHM13v2.0177,285,126 - 7,293,784 (+)NCBIT2T-CHM13v2.0
Tnk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81055,070,362 - 55,084,383 (-)NCBIGRCr8
mRatBN7.21054,571,396 - 54,580,547 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,571,117 - 54,579,940 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1059,234,510 - 59,240,807 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,723,078 - 58,729,377 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01054,230,740 - 54,237,047 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01056,458,650 - 56,475,183 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,459,108 - 56,465,393 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,203,769 - 56,212,284 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,692,319 - 56,698,602 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11056,705,941 - 56,714,918 (-)NCBI
Celera1053,726,241 - 53,732,527 (-)NCBICelera
Cytogenetic Map10q24NCBI
Tnk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554679,539,693 - 9,547,279 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554679,539,693 - 9,547,419 (-)NCBIChiLan1.0ChiLan1.0
TNK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21914,977,433 - 14,986,720 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11716,942,935 - 16,952,381 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,403,403 - 7,423,942 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1177,390,752 - 7,410,024 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,403,209 - 7,409,366 (+)Ensemblpanpan1.1panPan2
TNK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,320,029 - 32,326,829 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,321,272 - 32,326,158 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,457,980 - 32,464,791 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,425,348 - 32,432,175 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,425,395 - 32,432,143 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,390,791 - 32,397,611 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,349,550 - 32,356,377 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,526,593 - 32,533,420 (+)NCBIUU_Cfam_GSD_1.0
Tnk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,194,112 - 47,200,493 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936595668,315 - 674,136 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936595667,956 - 674,681 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,711,921 - 52,719,096 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,711,133 - 52,719,101 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21254,930,712 - 54,937,825 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TNK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,754,825 - 6,765,336 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl166,758,127 - 6,766,886 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605914,643,220 - 14,650,456 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247869,997,089 - 10,003,553 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247869,995,167 - 10,003,298 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tnk1
135 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1464
Count of miRNA genes:622
Interacting mature miRNAs:787
Transcripts:ENSMUST00000001626, ENSMUST00000108626, ENSMUST00000108628, ENSMUST00000125571, ENSMUST00000156507
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
36049778Ars6_mantibody response to SARS-CoV 6, day 15, IgM (mouse)116899082672490826Mouse
36049779Ars7_mantibody response to SARS-CoV 7, day 29, IgG1 (mouse)116899082672490826Mouse
36049784Ars8_mantibody response to SARS-CoV 8, day 29, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049785Ars9_mantibody response to SARS-CoV 9, day 29, IgM (mouse)116899082672490826Mouse
36049786Ars10_mantibody response to SARS-CoV 10, 4 days post-rechallenge, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049787Ars11_mantibody response to SARS-CoV 11, 4 days post-rechallenge, IgM (mouse)116899082672490826Mouse
36049788Ars1_mantibody response to SARS-CoV 1, day 7, IgG1 (mouse)116899082672490826Mouse
36049789Ars2_mantibody response to SARS-CoV 2, day 7, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049790Ars3_mantibody response to SARS-CoV 3, day 7, IgG2b (mouse)116899082672490826Mouse
36049791Ars4_mantibody response to SARS-CoV 4, day 7, IgG3 (mouse)116899082672490826Mouse
36049792Ars5_mantibody response to SARS-CoV 5, day 7, IgM (mouse)116899082672490826Mouse
35673314Ari2_mantibody response to influenza 2, day 10, IgG3 (mouse)116899082672490826Mouse

Markers in Region
D10Mit157.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map18E2UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map18A2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map18B1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map14C2UniSTS
Cytogenetic Map6A1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map13D2.1UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map17E3UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map6A3UniSTS
Cytogenetic Map5E4-E5UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map13DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map14D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic MapXDUniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map1H2.3UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15D2UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map16B2UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map1C4UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9F3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map9A4UniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map1A5UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map6G1UniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map9BUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map10A4UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map18A1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map1C2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map1BUniSTS
Cytogenetic Map17A3.1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map15A2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic Map4A3UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map8A1UniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map10B1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map4A1UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map5E3UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map14C1UniSTS
Cytogenetic Map14E5UniSTS
Cytogenetic Map10CUniSTS
Cytogenetic Map18B2UniSTS
Cytogenetic Map2F1UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map17A2UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17B2UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map4C4UniSTS
Cytogenetic Map3E3UniSTS
Cytogenetic Map11A4UniSTS
Cytogenetic Map4C5UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map7E1UniSTS
Cytogenetic Map5D-E1UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map17E4UniSTS
Cytogenetic Map1G2UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map4D2.1UniSTS
Cytogenetic Map4A5UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map1E3-E4UniSTS
Cytogenetic Map9F1-F3UniSTS
Cytogenetic Map1C1.1UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map12A2UniSTS
Cytogenetic Map17A3-BUniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map14A3UniSTS
Cytogenetic Map5G1.1UniSTS
Cytogenetic MapXF2-F4UniSTS
Cytogenetic Map7D2UniSTS
Cytogenetic Map2F3UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map9F1-F2UniSTS
Cytogenetic Map13A3.2UniSTS
Cytogenetic Map10A2UniSTS
Cytogenetic Map1C1UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map12D3UniSTS
Cytogenetic Map1A3-A5UniSTS
Cytogenetic Map2A2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic MapXA3.3UniSTS
Cytogenetic Map16A-B1UniSTS
Cytogenetic Map1D2.3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic MapXA2-A3.1UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map14A2-BUniSTS
Cytogenetic Map8E1-E2UniSTS
Cytogenetic Map8A3UniSTS
Cytogenetic Map1G3-H1UniSTS
Cytogenetic Map8B3-C1UniSTS
Cytogenetic Map19C1UniSTS
Cytogenetic Map8C5UniSTS
Cytogenetic Map8A4UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map14E4UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic MapXF5UniSTS
cM Map1040.0UniSTS
Whitehead Genetic1033.9UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000001626   ⟹   ENSMUSP00000001626
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,741,831 - 69,749,556 (-)Ensembl
GRCm38.p6 Ensembl1169,851,005 - 69,858,730 (-)Ensembl
RefSeq Acc Id: ENSMUST00000108626   ⟹   ENSMUSP00000104266
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,745,306 - 69,749,556 (-)Ensembl
GRCm38.p6 Ensembl1169,854,480 - 69,858,730 (-)Ensembl
RefSeq Acc Id: ENSMUST00000108628   ⟹   ENSMUSP00000104268
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,742,045 - 69,747,951 (-)Ensembl
GRCm38.p6 Ensembl1169,851,219 - 69,857,125 (-)Ensembl
RefSeq Acc Id: ENSMUST00000125571   ⟹   ENSMUSP00000118490
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,746,407 - 69,749,534 (-)Ensembl
GRCm38.p6 Ensembl1169,855,581 - 69,858,708 (-)Ensembl
RefSeq Acc Id: ENSMUST00000156507   ⟹   ENSMUSP00000120585
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,742,901 - 69,746,428 (-)Ensembl
GRCm38.p6 Ensembl1169,852,075 - 69,855,602 (-)Ensembl
RefSeq Acc Id: NM_031880   ⟹   NP_114086
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,741,389 - 69,749,556 (-)NCBI
GRCm381169,850,563 - 69,858,730 (-)ENTREZGENE
MGSCv371169,664,065 - 69,672,232 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006534554   ⟹   XP_006534617
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,741,845 - 69,749,537 (-)NCBI
GRCm381169,851,019 - 69,858,711 (-)NCBI
Sequence:
RefSeq Acc Id: XR_879778
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,741,845 - 69,749,525 (-)NCBI
GRCm381169,851,019 - 69,858,699 (-)NCBI
Sequence:
RefSeq Acc Id: NP_114086   ⟸   NM_031880
- UniProtKB: Q8K0X9 (UniProtKB/Swiss-Prot),   Q8CCC4 (UniProtKB/Swiss-Prot),   Q91V11 (UniProtKB/Swiss-Prot),   Q99ML2 (UniProtKB/Swiss-Prot),   Q5F2B4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006534617   ⟸   XM_006534554
- Peptide Label: isoform X1
- UniProtKB: Q8K0X9 (UniProtKB/Swiss-Prot),   Q8CCC4 (UniProtKB/Swiss-Prot),   Q91V11 (UniProtKB/Swiss-Prot),   Q99ML2 (UniProtKB/Swiss-Prot),   Q5F2B4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000118490   ⟸   ENSMUST00000125571
RefSeq Acc Id: ENSMUSP00000001626   ⟸   ENSMUST00000001626
RefSeq Acc Id: ENSMUSP00000104266   ⟸   ENSMUST00000108626
RefSeq Acc Id: ENSMUSP00000104268   ⟸   ENSMUST00000108628
RefSeq Acc Id: ENSMUSP00000120585   ⟸   ENSMUST00000156507
Protein Domains
Protein kinase   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99ML2-F1-model_v2 AlphaFold Q99ML2 1-666 view protein structure

Promoters
RGD ID:6822362
Promoter ID:MM_KWN:8131
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Spleen
Transcripts:ENSMUST00000108628
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361169,671,296 - 69,671,796 (-)MPROMDB
RGD ID:6822359
Promoter ID:MM_KWN:8132
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Lung
Transcripts:ENSMUST00000094063,   ENSMUST00000102583,   ENSMUST00000108626,   ENSMUST00000108631,   NM_031880,   OTTMUST00000013474
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361169,672,006 - 69,672,506 (-)MPROMDB
RGD ID:8675236
Promoter ID:EPDNEW_M15648
Type:initiation region
Name:Tnk1_1
Description:Mus musculus tyrosine kinase, non-receptor, 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381169,858,732 - 69,858,792EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1930958 AgrOrtholog
Ensembl Genes ENSMUSG00000001583 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000001626 ENTREZGENE
  ENSMUST00000001626.10 UniProtKB/Swiss-Prot
  ENSMUST00000108626.8 UniProtKB/Swiss-Prot
  ENSMUST00000108628 ENTREZGENE
  ENSMUST00000108628.8 UniProtKB/TrEMBL
  ENSMUST00000125571.2 UniProtKB/TrEMBL
  ENSMUST00000156507.2 UniProtKB/TrEMBL
Gene3D-CATH SH3 Domains UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot
  SH3_domain UniProtKB/Swiss-Prot
  Tyr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:83813 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1930958 ENTREZGENE
NCBI Gene 83813 ENTREZGENE
PANTHER EPIDERMAL GROWTH FACTOR RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NON-RECEPTOR TYROSINE-PROTEIN KINASE TNK1 UniProtKB/TrEMBL
  TYROSINE-PROTEIN KINASE UniProtKB/TrEMBL
  TYROSINE-PROTEIN KINASE RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pkinase_Tyr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tnk1 PhenoGen
PRINTS TYRKINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot
SMART TyrKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/Swiss-Prot
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2ARN2_MOUSE UniProtKB/TrEMBL
  Q3TJU8_MOUSE UniProtKB/TrEMBL
  Q5F2B4 ENTREZGENE, UniProtKB/TrEMBL
  Q5F2B6_MOUSE UniProtKB/TrEMBL
  Q8CCC4 ENTREZGENE
  Q8K0X9 ENTREZGENE
  Q91V11 ENTREZGENE
  Q99ML2 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q8CCC4 UniProtKB/Swiss-Prot
  Q8K0X9 UniProtKB/Swiss-Prot
  Q91V11 UniProtKB/Swiss-Prot