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Gene: Hsph1 (heat shock 105kDa/110kDa protein 1) Mus musculus
Symbol: Hsph1
Name: heat shock 105kDa/110kDa protein 1
Description: Exhibits alpha-tubulin binding activity. Involved in several processes, including chaperone cofactor-dependent protein refolding; negative regulation of intracellular signal transduction; and positive regulation of macromolecule metabolic process. Localizes to the cytoplasm and nucleus. Colocalizes with the microtubule. Is expressed in several structures, including brain; genitourinary system; gut; integumental system; and liver and biliary system. Orthologous to human HSPH1 (heat shock protein family H (Hsp110) member 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (2,4,5-trichlorophenoxy)acetic acid; (S)-amphetamine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 105kDa; 42 degrees C-HSP; AI790491; heat shock 110 kDa protein; heat shock protein 105 kDa; heat shock protein 110; heat shock protein, 105 kDa; heat shock-related 100 kDa protein E7I; hsp-E7I; Hsp105; HSP105 42 C-HSP; Hsp110; hsp110/105
Homo sapiens (human) : HSPH1 (heat shock protein family H (Hsp110) member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hsph1 (heat shock protein family H (Hsp110) member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hsph1 (heat shock protein family H (Hsp110) member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HSPH1 (heat shock protein family H (Hsp110) member 1)
Canis lupus familiaris (dog) : HSPH1 (heat shock protein family H (Hsp110) member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hsph1 (heat shock protein family H (Hsp110) member 1)
Sus scrofa (pig) : HSPH1 (heat shock protein family H (Hsp110) member 1)
Chlorocebus sabaeus (African green monkey) : HSPH1 (heat shock protein family H (Hsp110) member 1)
Heterocephalus glaber (naked mole-rat) : Hsph1 (heat shock protein family H (Hsp110) member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl5149,614,287 - 149,636,376 (-)Ensembl
GRCm385149,616,843 - 149,636,498 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375150,419,420 - 150,438,890 (-)NCBIGRCm37mm9NCBIm37
MGSCv365149,885,224 - 149,904,597 (-)NCBImm8
Celera5147,617,650 - 147,637,130 (-)NCBICelera
Cytogenetic Map5G3NCBI
cM Map589.18NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hsph1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323158
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.