Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of BTBD7 mRNA | CTD | PMID:22206623 | 17beta-estradiol | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of BTBD7 mRNA | CTD | PMID:19167446 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Btbd7 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of BTBD7 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Btbd7 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of BTBD7 mRNA | CTD | PMID:33387578 | 2-methylcholine | affects expression | ISO | BTBD7 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of BTBD7 mRNA | CTD | PMID:21179406 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of BTBD7 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of BTBD7 mRNA | CTD | PMID:28628672 | acrolein | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of BTBD7 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of BTBD7 mRNA | CTD | PMID:32699268 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of BTBD7 mRNA | CTD | PMID:19770486 | aflatoxin B1 | decreases methylation | ISO | BTBD7 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of BTBD7 gene | CTD | PMID:27153756 | alpha-pinene | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of BTBD7 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of BTBD7 mRNA | CTD | PMID:32699268 | antirheumatic drug | increases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of BTBD7 mRNA | CTD | PMID:24449571 | arsane | affects methylation | ISO | BTBD7 (Homo sapiens) | 6480464 | Arsenic affects the methylation of BTBD7 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | BTBD7 (Homo sapiens) | 6480464 | Arsenic affects the methylation of BTBD7 gene | CTD | PMID:25304211 | avobenzone | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | avobenzone results in decreased expression of BTBD7 mRNA | CTD | PMID:29981360 | avobenzone | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | avobenzone inhibits the reaction [IFI27 mRNA results in increased expression of BTBD7 mRNA] and IFI27 mRNA inhibits the reaction [avobenzone results in decreased expression of BTBD7 mRNA] | CTD | PMID:29981360 | benzo[a]pyrene | increases methylation | ISO | BTBD7 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of BTBD7 3' UTR and Benzo(a)pyrene results in increased methylation of BTBD7 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | benzo[a]pyrene diol epoxide I | increases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:26238291 | bisphenol A | affects expression | ISO | Btbd7 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of BTBD7 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Btbd7 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of BTBD7 mRNA | CTD | PMID:32145629 | butanal | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of BTBD7 mRNA | CTD | PMID:26079696 | CGP 52608 | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to BTBD7 gene] | CTD | PMID:28238834 | copper atom | increases expression | ISO | Btbd7 (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of BTBD7 mRNA | CTD | PMID:26033743 | copper(0) | increases expression | ISO | Btbd7 (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of BTBD7 mRNA | CTD | PMID:26033743 | copper(II) sulfate | increases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of BTBD7 mRNA | CTD | PMID:19549813 | coumestrol | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of BTBD7 mRNA | CTD | PMID:19167446 | dexamethasone | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of BTBD7 mRNA | CTD | PMID:28628672 | disodium selenite | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Sodium Selenite results in decreased expression of BTBD7 mRNA | CTD | PMID:18175754 | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of BTBD7 mRNA | CTD | PMID:35436446 | ethyl methanesulfonate | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of BTBD7 mRNA | CTD | PMID:23649840 | formaldehyde | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of BTBD7 mRNA | CTD | PMID:20655997 | FR900359 | decreases phosphorylation | ISO | BTBD7 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of BTBD7 protein | CTD | PMID:37730182 | indometacin | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of BTBD7 mRNA | CTD | PMID:28628672 | lead diacetate | decreases expression | EXP | | 6480464 | lead acetate results in decreased expression of BTBD7 mRNA | CTD | PMID:21829687 | niclosamide | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Niclosamide results in decreased expression of BTBD7 mRNA | CTD | PMID:36318118 | orphenadrine | affects expression | ISO | Btbd7 (Rattus norvegicus) | 6480464 | Orphenadrine affects the expression of BTBD7 mRNA | CTD | PMID:23665939 | ozone | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of BTBD7 mRNA more ... | CTD | PMID:32699268 | paracetamol | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of BTBD7 mRNA | CTD | PMID:21420995 | pentanal | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | pentanal results in decreased expression of BTBD7 mRNA | CTD | PMID:26079696 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of BTBD7 mRNA | CTD | PMID:23091169 | silicon dioxide | increases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of BTBD7 mRNA and Silicon Dioxide results in increased expression of BTBD7 mRNA | CTD | PMID:25351596 and PMID:25895662 | silver atom | decreases expression | EXP | | 6480464 | Silver results in decreased expression of BTBD7 mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | EXP | | 6480464 | Silver results in decreased expression of BTBD7 mRNA | CTD | PMID:27131904 | sodium arsenate | increases expression | EXP | | 6480464 | sodium arsenate results in increased expression of BTBD7 mRNA | CTD | PMID:21795629 | tamoxifen | decreases expression | EXP | | 6480464 | Tamoxifen results in decreased expression of BTBD7 mRNA | CTD | PMID:25123088 | thioacetamide | increases expression | ISO | Btbd7 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of BTBD7 mRNA | CTD | PMID:23411599 and PMID:34492290 | trichloroethene | decreases methylation | ISO | Btbd7 (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased methylation of BTBD7 gene | CTD | PMID:27618143 | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of BTBD7 mRNA | CTD | PMID:28973697 | valproic acid | decreases methylation | ISO | BTBD7 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of BTBD7 gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of BTBD7 mRNA | CTD | PMID:27188386 | valproic acid | affects splicing | ISO | Btbd7 (Rattus norvegicus) | 6480464 | Valproic Acid affects the splicing of BTBD7 mRNA | CTD | PMID:29427782 | | 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Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
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Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
Disease Annotations
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Gene-Chemical Interaction Annotations
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Mammalian Phenotype
References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Mouse brain organization revealed through direct genome-scale TF expression analysis. | Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7. |
| 2. | Functional annotation of a full-length mouse cDNA collection. | Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90. |
| 3. | MGDs mouse GO annotations | MGD data from the GO Consortium |
| 4. | Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. | Okazaki N, etal., DNA Res 2003 Feb 28;10(1):35-48. |
| 5. | Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. | Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73. |
| 6. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 7. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:8889548 | PMID:10349636 | PMID:10922068 | PMID:11042159 | PMID:11076861 | PMID:11527404 | PMID:12477932 | PMID:14610273 | PMID:15489334 | PMID:16141072 | PMID:16141073 | PMID:18287559 |
| PMID:20412781 | PMID:20671187 | PMID:21677750 | PMID:21873635 | PMID:27369076 | PMID:34323105 |
Genomics
Comparative Map Data
| Btbd7 (Mus musculus - house mouse) |
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| BTBD7 (Homo sapiens - human) |
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| Btbd7 (Rattus norvegicus - Norway rat) |
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| Btbd7 (Chinchilla lanigera - long-tailed chinchilla) |
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| BTBD7 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| BTBD7 (Canis lupus familiaris - dog) |
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| Btbd7 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| BTBD7 (Sus scrofa - pig) |
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| BTBD7 (Chlorocebus sabaeus - green monkey) |
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| Btbd7 (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Btbd7
2394 total Variants 
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