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Gene: Tpm3 (tropomyosin 3, gamma) Mus musculus
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Symbol: Tpm3
Name: tropomyosin 3, gamma
Description: Exhibits actin filament binding activity. Predicted to be involved in actin filament organization and muscle contraction. Localizes to cortical cytoskeleton; growth cone; and podosome. Colocalizes with cleavage furrow. Is expressed in coelomic epithelium of testis; ovary; and primary sex cord. Human ortholog(s) of this gene implicated in congenital fiber-type disproportion and nemaline myopathy 1. Orthologous to human TPM3 (tropomyosin 3); PARTICIPATES IN dilated cardiomyopathy pathway; hypertrophic cardiomyopathy pathway; thyroid cancer pathway; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: gamma-TM; gamma-tropomyosin; hTM30nm; hTMnm; MGC102590; skalphaTM.2; TM30nm; Tm5NM; TMnm; Tpm-5; Tpm5; Trop-5; tropomyosin 5; tropomyosin alpha-3 chain; tropomyosin-3
Orthologs:
Homo sapiens (human) : TPM3 (tropomyosin 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tpm3 (tropomyosin 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tpm3 (tropomyosin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TPM3 (tropomyosin 3)
Canis lupus familiaris (dog) : TPM3 (tropomyosin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tpm3 (tropomyosin 3)
Sus scrofa (pig) : TPM3 (tropomyosin 3)
Chlorocebus sabaeus (African green monkey) : TPM3 (tropomyosin 3)
Heterocephalus glaber (naked mole-rat) : Tpm3 (tropomyosin 3)
more info ...
Related Pseudogenes: Tpm3-rs2   Tpm3-rs3   Tpm3-rs7  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl390,072,649 - 90,100,902 (+)EnsemblGRCm38mm10GRCm38
GRCm38390,072,651 - 90,100,902 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37389,876,616 - 89,904,526 (+)NCBIGRCm37mm9NCBIm37
MGSCv36390,158,621 - 90,186,531 (+)NCBImm8
Celera390,109,227 - 90,137,142 (+)NCBICelera
Cytogenetic Map3F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tpm3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731511
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.