Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Tpm3 (tropomyosin 3, gamma) Mus musculus
Symbol: Tpm3
Name: tropomyosin 3, gamma
Description: Exhibits actin filament binding activity. Predicted to be involved in actin filament organization and muscle contraction. Localizes to cortical cytoskeleton; growth cone; and podosome. Colocalizes with cleavage furrow. Is expressed in coelomic epithelium of testis; ovary; and primary sex cord. Human ortholog(s) of this gene implicated in congenital fiber-type disproportion and nemaline myopathy 1. Orthologous to human TPM3 (tropomyosin 3); PARTICIPATES IN dilated cardiomyopathy pathway; hypertrophic cardiomyopathy pathway; thyroid cancer pathway; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: gamma-TM; gamma-tropomyosin; hTM30nm; hTMnm; MGC102590; skalphaTM.2; TM30nm; Tm5NM; TMnm; Tpm-5; Tpm5; Trop-5; tropomyosin 5; tropomyosin alpha-3 chain; tropomyosin-3
Homo sapiens (human) : TPM3 (tropomyosin 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tpm3 (tropomyosin 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tpm3 (tropomyosin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TPM3 (tropomyosin 3)
Canis lupus familiaris (dog) : TPM3 (tropomyosin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tpm3 (tropomyosin 3)
Sus scrofa (pig) : TPM3 (tropomyosin 3)
Chlorocebus sabaeus (African green monkey) : TPM3 (tropomyosin 3)
Heterocephalus glaber (naked mole-rat) : Tpm3 (tropomyosin 3)
more info ...
Related Pseudogenes: Tpm3-rs2   Tpm3-rs3   Tpm3-rs7  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl390,072,649 - 90,100,902 (+)EnsemblGRCm38mm10GRCm38
GRCm38390,072,651 - 90,100,902 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37389,876,616 - 89,904,526 (+)NCBIGRCm37mm9NCBIm37
MGSCv36390,158,621 - 90,186,531 (+)NCBImm8
Celera390,109,227 - 90,137,142 (+)NCBICelera
Cytogenetic Map3F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tpm3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731511
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.