Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Fdps (farnesyl diphosphate synthetase) Mus musculus
Analyze
Symbol: Fdps
Name: farnesyl diphosphate synthetase
Description: Predicted to have dimethylallyltranstransferase activity and geranyltranstransferase activity. Predicted to be involved in farnesyl diphosphate biosynthetic process; positive regulation of cell growth involved in cardiac muscle cell development; and positive regulation of cholesterol biosynthetic process. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in porokeratosis. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human FDPS (farnesyl diphosphate synthase); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; INTERACTS WITH 1,2-dichloroethane; 17beta-estradiol; 17beta-hydroxy-5alpha-androstan-3-one.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: (2E,6E)-farnesyl diphosphate synthase; 6030492I17Rik; AI256750; cholesterol-regulated 39 kDa protein; CR 39; dimethylallyltranstransferase; farnesyl diphosphate synthase; farnesyl pyrophosphate synthase; farnesyl pyrophosphate synthetase; Fdpsl1; FPP synthase; FPP synthetase; FPS; geranyltranstransferase; MGC107162; mKIAA1293
Orthologs:
Homo sapiens (human) : FDPS (farnesyl diphosphate synthase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fdps (farnesyl diphosphate synthase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fdps (farnesyl diphosphate synthase)
Pan paniscus (bonobo/pygmy chimpanzee) : FDPS (farnesyl diphosphate synthase)
Canis lupus familiaris (dog) : FDPS (farnesyl diphosphate synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fdps (farnesyl diphosphate synthase)
Sus scrofa (pig) : FDPS (farnesyl diphosphate synthase)
more info ...
Related Pseudogenes: Gm18546   Gm18592   Gm3571   Gm5873   Gm7513   Gm7979   Gm8163  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38389,093,588 - 89,101,967 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37388,897,510 - 88,905,867 (-)NCBIGRCm37mm9NCBIm37
MGSCv36389,179,515 - 89,187,872 (-)NCBImm8
Celera389,132,279 - 89,140,658 (-)NCBICelera
Cytogenetic Map3 F1NCBI
cM Map339.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fdps
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69023
Created: 2001-11-06
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.