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Gene: Fdps (farnesyl diphosphate synthetase) Mus musculus
Symbol: Fdps
Name: farnesyl diphosphate synthetase
Description: Predicted to have dimethylallyltranstransferase activity and geranyltranstransferase activity. Predicted to be involved in farnesyl diphosphate biosynthetic process; positive regulation of cell growth involved in cardiac muscle cell development; and positive regulation of cholesterol biosynthetic process. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in porokeratosis. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human FDPS (farnesyl diphosphate synthase); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; INTERACTS WITH 1,2-dichloroethane; 17beta-estradiol; 17beta-hydroxy-5alpha-androstan-3-one.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: (2E,6E)-farnesyl diphosphate synthase; 6030492I17Rik; AI256750; cholesterol-regulated 39 kDa protein; CR 39; dimethylallyltranstransferase; farnesyl diphosphate synthase; farnesyl pyrophosphate synthase; farnesyl pyrophosphate synthetase; Fdpsl1; FPP synthase; FPP synthetase; FPS; geranyltranstransferase; MGC107162; mKIAA1293
Homo sapiens (human) : FDPS (farnesyl diphosphate synthase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fdps (farnesyl diphosphate synthase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fdps (farnesyl diphosphate synthase)
Pan paniscus (bonobo/pygmy chimpanzee) : FDPS (farnesyl diphosphate synthase)
Canis lupus familiaris (dog) : FDPS (farnesyl diphosphate synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fdps (farnesyl diphosphate synthase)
Sus scrofa (pig) : FDPS (farnesyl diphosphate synthase)
more info ...
Related Pseudogenes: Gm18546   Gm18592   Gm3571   Gm5873   Gm7513   Gm7979   Gm8163  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38389,093,588 - 89,101,967 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37388,897,510 - 88,905,867 (-)NCBIGRCm37mm9NCBIm37
MGSCv36389,179,515 - 89,187,872 (-)NCBImm8
Celera389,132,279 - 89,140,658 (-)NCBICelera
Cytogenetic Map3 F1NCBI
cM Map339.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Fdps
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69023
Created: 2001-11-06
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.