Grin2b (glutamate receptor, ionotropic, NMDA2B (epsilon 2)) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Grin2b (glutamate receptor, ionotropic, NMDA2B (epsilon 2)) Mus musculus
Analyze
Symbol: Grin2b
Name: glutamate receptor, ionotropic, NMDA2B (epsilon 2)
RGD ID: 10687
MGI Page MGI
Description: Exhibits NMDA glutamate receptor activity; calcium channel activity; and neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential. Involved in several processes, including behavioral fear response; detection of mechanical stimulus involved in sensory perception of pain; and learning or memory. Localizes to several cellular components, including NMDA selective glutamate receptor complex; cytoplasmic vesicle; and synaptic membrane. Is expressed in several structures, including adipose tissue; central nervous system; eye; genitourinary system; and gut. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; autosomal dominant non-syndromic intellectual disability 6; bipolar disorder; developmental and epileptic encephalopathy 27; and neurodegenerative disease (multiple). Orthologous to human GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; excitatory synaptic transmission pathway; long term potentiation; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW490526; expressed sequence AW490526; GluN; GluN2B; GluRepsilon2; glutamate [NMDA] receptor subunit epsilon-2; glutamate receptor ionotropic, NMDA 2B; N-methyl D-aspartate receptor 2B; N-methyl D-aspartate receptor subtype 2B; NMDA; Nmdar2b; NR; NR2B
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396135,690,219 - 136,150,658 (-)NCBIGRCm39mm39
GRCm39 Ensembl6135,690,231 - 136,150,509 (-)Ensembl
GRCm386135,713,221 - 136,173,615 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6135,713,233 - 136,173,511 (-)EnsemblGRCm38mm10GRCm38
MGSCv376135,679,813 - 136,123,529 (-)NCBIGRCm37mm9NCBIm37
MGSCv366135,697,791 - 136,009,994 (-)NCBImm8
Celera6138,678,301 - 139,123,902 (-)NCBICelera
Cytogenetic Map6G1NCBI
cM Map666.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
3,4-methylenedioxymethamphetamine  (EXP,ISO)
4-[1-hydroxy-2-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-azacytidine  (EXP)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
all-trans-retinoic acid  (ISO)
ammonium acetate  (ISO)
ammonium chloride  (EXP)
amphetamine  (ISO)
arsenite(3-)  (EXP,ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Butylparaben  (ISO)
capsaicin  (ISO)
capsazepine  (ISO)
carbon dioxide  (ISO)
carbon nanotube  (ISO)
celecoxib  (EXP)
chaetocin  (ISO)
chloroquine  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
citalopram  (ISO)
clozapine  (ISO)
cocaine  (ISO)
colforsin daropate hydrochloride  (ISO)
crocidolite asbestos  (ISO)
cyhalothrin  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (EXP,ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
dextromethorphan  (ISO)
diazinon  (EXP,ISO)
dibutyl phthalate  (ISO)
dieldrin  (ISO)
diminazene diaceturate  (EXP)
dioxygen  (ISO)
enzacamene  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP,ISO)
excitatory amino acid agonist  (ISO)
felbamate  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
fulvestrant  (ISO)
haloperidol  (EXP)
ionomycin  (ISO)
isoflurane  (ISO)
kainic acid  (EXP)
ketamine  (ISO)
lead diacetate  (EXP,ISO)
leflunomide  (ISO)
linuron  (ISO)
lipopolysaccharide  (EXP)
lipoteichoic acid  (EXP)
lithium atom  (ISO)
lithium hydride  (ISO)
lovastatin  (ISO)
magnesium atom  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
melamine  (ISO)
methamphetamine  (EXP,ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
morphine  (EXP,ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-acetyl-L-cysteine  (ISO)
nickel atom  (ISO)
nobiletin  (ISO)
notoginsenoside R1  (ISO)
NS-398  (ISO)
Ondansetron  (ISO)
oxidopamine  (ISO)
paclitaxel  (ISO)
paraquat  (EXP,ISO)
PCB138  (EXP,ISO)
pentobarbital  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (EXP)
potassium dichromate  (EXP)
prochloraz  (ISO)
procymidone  (ISO)
pyridine  (ISO)
remifentanil  (ISO)
resveratrol  (ISO)
Rhynchophylline  (ISO)
rimonabant  (EXP)
sarin  (ISO)
sevoflurane  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP)
sodium fluoride  (ISO)
spermine  (ISO)
sulfur dioxide  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrodotoxin  (EXP)
thimerosal  (EXP)
titanium dioxide  (EXP)
toluene  (EXP,ISO)
tributylstannane  (ISO)
trimethyltin  (EXP)
triptonide  (EXP)
valproic acid  (ISO)
venlafaxine hydrochloride  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
action potential  (ISO)
associative learning  (ISO)
behavioral fear response  (IMP,ISO)
behavioral response to pain  (IMP)
calcium ion transmembrane import into cytosol  (ISO)
calcium ion transport  (IMP)
cation transport  (IGI)
cellular response to amino acid stimulus  (ISO)
cellular response to corticosterone stimulus  (ISO)
cellular response to curcumin  (ISO)
cellular response to dsRNA  (ISO)
cellular response to forskolin  (ISO)
cellular response to growth factor stimulus  (ISO)
cellular response to lipid  (ISO)
cellular response to magnesium starvation  (ISO)
cellular response to manganese ion  (ISO)
cellular response to organic cyclic compound  (ISO)
cerebral cortex development  (ISO)
chemical synaptic transmission  (IMP)
detection of mechanical stimulus involved in sensory perception of pain  (IMP)
excitatory postsynaptic potential  (IBA,IGI,IMP)
fear response  (IMP)
hippocampus development  (ISO)
in utero embryonic development  (IMP)
ion transport  (IEA)
ionotropic glutamate receptor signaling pathway  (ISO)
learning  (IDA,IMP)
learning or memory  (ISO,TAS)
long-term memory  (ISO)
long-term synaptic potentiation  (IBA,IGI,IMP)
memory  (IDA,IMP,ISO)
multicellular organismal response to stress  (ISO)
negative regulation of dendritic spine maintenance  (IGI)
NMDA selective glutamate receptor signaling pathway  (ISO)
positive regulation of cell death  (ISO)
positive regulation of cysteine-type endopeptidase activity  (ISO)
positive regulation of glutamate secretion  (ISO)
positive regulation of neuron death  (IGI)
positive regulation of synaptic transmission  (ISO)
protein heterotetramerization  (ISO)
receptor clustering  (ISO)
regulation of long-term neuronal synaptic plasticity  (ISO)
regulation of MAPK cascade  (ISO)
regulation of neuronal synaptic plasticity  (TAS)
regulation of postsynaptic cytosolic calcium ion concentration  (ISO)
regulation of postsynaptic membrane potential  (IMP)
regulation of protein kinase A signaling  (IMP)
regulation of synaptic plasticity  (IMP)
response to amine  (ISO)
response to amphetamine  (ISO)
response to calcium ion  (ISO)
response to carbohydrate  (ISO)
response to cocaine  (ISO)
response to cytokine  (ISO)
response to electrical stimulus  (ISO)
response to ethanol  (IMP,ISO)
response to fungicide  (ISO)
response to growth hormone  (ISO)
response to hypoxia  (ISO)
response to magnesium ion  (ISO)
response to manganese ion  (ISO)
response to mechanical stimulus  (ISO)
response to methylmercury  (ISO)
response to organic cyclic compound  (ISO)
response to organonitrogen compound  (ISO)
response to other organism  (ISO)
response to toxic substance  (ISO)
rhythmic process  (ISO)
sensitization  (ISO)
sensory organ development  (IMP)
startle response  (IGI,IMP)
suckling behavior  (IMP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal AMPA-mediated synaptic currents  (IAGP)
abnormal associative learning  (IAGP)
abnormal CNS synaptic transmission  (IAGP)
abnormal cued conditioning behavior  (IAGP)
abnormal dendrite morphology  (IAGP)
abnormal dendritic spine morphology  (IAGP)
abnormal discrimination learning  (IAGP)
abnormal excitatory postsynaptic currents  (IAGP)
abnormal excitatory postsynaptic potential  (IAGP)
abnormal learning/memory/conditioning  (IAGP)
abnormal long term depression  (IAGP)
abnormal miniature excitatory postsynaptic currents  (IAGP)
abnormal motor coordination/balance  (IAGP)
abnormal nervous system physiology  (IAGP)
abnormal NMDA-mediated synaptic currents  (IAGP)
abnormal object recognition memory  (IAGP)
abnormal operant conditioning behavior  (IAGP)
abnormal social investigation  (IAGP)
abnormal social/conspecific interaction  (IAGP)
abnormal spatial learning  (IAGP)
abnormal spatial reference memory  (IAGP)
abnormal spatial working memory  (IAGP)
abnormal suckling behavior  (IAGP)
abnormal synapse morphology  (IAGP)
abnormal temporal memory  (IAGP)
absence of NMDA-mediated synaptic currents  (IAGP)
absent gastric milk in neonates  (IAGP)
absent long term depression  (IAGP)
absent suckling reflex  (IAGP)
decreased anxiety-related response  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased physiological sensitivity to xenobiotic  (IAGP)
disorganized barrel cortex  (IAGP)
enhanced long term potentiation  (IAGP)
hyperactivity  (IAGP)
impaired coordination  (IAGP)
impaired swimming  (IAGP)
impaired synaptic plasticity  (IAGP)
increased prepulse inhibition  (IAGP)
increased startle reflex  (IAGP)
increased thigmotaxis  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
perinatal lethality  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
preweaning lethality, incomplete penetrance  (IEA)
reduced long term depression  (IAGP)
reduced long term potentiation  (IAGP)
social withdrawal  (IAGP)
References

References - curated
1. Andreoli V, etal., J Neural Transm (Vienna). 2014 May;121(5):533-42. doi: 10.1007/s00702-013-1125-7. Epub 2013 Dec 1.
2. Anu J, etal., Eur J Pharmacol. 2010 Mar 25;630(1-3):61-8. Epub 2010 Jan 6.
3. Arning L, etal., Hum Genet. 2007 Sep;122(2):175-82. Epub 2007 Jun 14.
4. Arning L, etal., Neurogenetics. 2005 Feb;6(1):25-8. Epub 2004 Nov 17.
5. Bartlett TE, etal., Neuropharmacology. 2007 Jan;52(1):60-70. Epub 2006 Aug 10.
6. Borbely S, etal., Neuroscience. 2009 Mar 3;159(1):358-68. Epub 2008 Dec 27.
7. Coultrap SJ and Bayer KU, Trends Neurosci. 2012 Oct;35(10):607-18. doi: 10.1016/j.tins.2012.05.003. Epub 2012 Jun 19.
8. Dos-Anjos S, etal., Neuroscience. 2009 Dec 15;164(3):1119-26. Epub 2009 Sep 15.
9. Fan J, etal., Gastroenterology. 2009 May;136(5):1732-40.e3. Epub 2009 Feb 6.
10. Fan MM, etal., J Neurosci. 2007 Apr 4;27(14):3768-79.
11. Ferrier J, etal., PLoS One. 2013 Oct 30;8(10):e77828. doi: 10.1371/journal.pone.0077828. eCollection 2013.
12. Geng SJ, etal., Exp Neurol. 2010 Apr;222(2):256-66. Epub 2010 Jan 14.
13. GrĂ¼nder T, etal., Vis Neurosci. 2001 Sep-Oct;18(5):781-7.
14. Gulchina Y, etal., J Neurochem. 2017 Nov;143(3):320-333. doi: 10.1111/jnc.14101. Epub 2017 Sep 5.
15. Huang P, etal., Nan Fang Yi Ke Da Xue Xue Bao. 2010 Apr;30(4):708-11.
16. Huo XL, etal., PLoS One. 2014 Apr 9;9(4):e94278. doi: 10.1371/journal.pone.0094278. eCollection 2014.
17. Ishihama K, etal., Arch Histol Cytol. 2005 Dec;68(4):321-35.
18. Jensen V, etal., Neuroscience. 2009 Jan 12;158(1):353-64. doi: 10.1016/j.neuroscience.2008.05.016. Epub 2008 May 21.
19. Jiang H and Jia J, Neurosci Lett. 2009 Feb 6;450(3):356-60. doi: 10.1016/j.neulet.2008.10.075. Epub 2008 Oct 25.
20. Jiang X, etal., Neurobiol Aging. 2015 Feb;36(2):867-76. doi: 10.1016/j.neurobiolaging.2014.10.018. Epub 2014 Oct 16.
21. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
22. Kim E, etal., Am J Physiol Regul Integr Comp Physiol. 2010 Jun;298(6):R1588-96. Epub 2010 Mar 17.
23. Kim JH, etal., Neurosci Res. 2006 Oct;56(2):220-3. Epub 2006 Sep 5.
24. Leuba G, etal., Curr Alzheimer Res. 2014 Jan;11(1):86-96.
25. Levenson JM, etal., Biochim Biophys Acta. 2008 Aug;1779(8):422-31. Epub 2008 Jan 12.
26. Lewis B, etal., Pharmacol Biochem Behav. 2012 Jan;100(3):545-53. doi: 10.1016/j.pbb.2011.10.013. Epub 2011 Oct 20.
27. Li D and He L, Genet Med. 2007 Jan;9(1):4-8.
28. Li R, etal., BMC Neurosci. 2007 Jul 26;8:55.
29. Lisman J, etal., Nat Rev Neurosci. 2012 Feb 15;13(3):169-82. doi: 10.1038/nrn3192.
30. Martucci L, etal., Schizophr Res. 2006 Jun;84(2-3):214-21. Epub 2006 Mar 20.
31. Martynyuk AE, etal., Mol Genet Metab. 2005 Dec;86 Suppl 1:S34-42. Epub 2005 Sep 8.
32. Mathern GW, etal., Epilepsy Res. 1998 Sep;32(1-2):154-71.
33. MGD and Homologene mouse data transfer
34. MGD data from the GO Consortium
35. MGD IEA
36. Mohamed NE, etal., J Alzheimers Dis. 2015;44(2):431-7. doi: 10.3233/JAD-141764.
37. Montori S, etal., Neurochem Int. 2010 Jul;56(8):878-85. Epub 2010 Mar 27.
38. OMIM Disease Annotation Pipeline
39. Pipeline to import KEGG annotations from KEGG into RGD
40. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
41. RGD automated import pipeline
42. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
43. RGD automated import pipeline for gene-chemical interactions
44. Schober ME, etal., Am J Physiol Regul Integr Comp Physiol. 2009 Mar;296(3):R681-92. Epub 2009 Jan 14.
45. Seripa D, etal., Dement Geriatr Cogn Disord. 2008;25(3):287-92. doi: 10.1159/000118634. Epub 2008 Feb 26.
46. Tunc-Ozcan E, etal., Alcohol Clin Exp Res. 2013 Nov;37(11):1986-95. doi: 10.1111/acer.12183. Epub 2013 Jun 13.
47. Wei B, etal., Brain Res. 2016 Jan 15;1631:157-64. doi: 10.1016/j.brainres.2015.11.041. Epub 2015 Dec 2.
48. Wernicke C, etal., Biol Psychiatry. 2003 Nov 1;54(9):922-8.
49. Zhang-James Y, etal., Dev Neurosci. 2012;34(2-3):218-27. Epub 2012 Jul 6.
Additional References at PubMed
PMID:1377365   PMID:1493227   PMID:7510577   PMID:7518474   PMID:7518475   PMID:7531804   PMID:7723623   PMID:7929904   PMID:7959773   PMID:7999784   PMID:8015722   PMID:8036251  
PMID:8180471   PMID:8595214   PMID:8601798   PMID:8699248   PMID:8702910   PMID:8756432   PMID:8789948   PMID:8840015   PMID:8889548   PMID:8965641   PMID:8996814   PMID:9003035  
PMID:9004271   PMID:9011744   PMID:9147327   PMID:9192668   PMID:9458051   PMID:9514948   PMID:9647694   PMID:9768843   PMID:9822733   PMID:9892651   PMID:10331083   PMID:10349636  
PMID:10479680   PMID:10485698   PMID:10485705   PMID:10620012   PMID:10634899   PMID:10767319   PMID:10846156   PMID:10862698   PMID:11024032   PMID:11042159   PMID:11076861   PMID:11161799  
PMID:11306676   PMID:11344110   PMID:11488959   PMID:11530236   PMID:11711849   PMID:11719203   PMID:11920728   PMID:11988580   PMID:12008020   PMID:12103442   PMID:12111856   PMID:12147342  
PMID:12191494   PMID:12451687   PMID:12466851   PMID:12514209   PMID:12531901   PMID:12676993   PMID:12738868   PMID:12816890   PMID:12832518   PMID:12888804   PMID:12890763   PMID:12957649  
PMID:14602821   PMID:14622581   PMID:14643751   PMID:14645471   PMID:14662797   PMID:14686892   PMID:15102836   PMID:15193753   PMID:15240759   PMID:15328026   PMID:15519237   PMID:15584924  
PMID:15663482   PMID:15716419   PMID:15748150   PMID:15755907   PMID:15862890   PMID:16025111   PMID:16033900   PMID:16045501   PMID:16141072   PMID:16141073   PMID:16157280   PMID:16172120  
PMID:16186258   PMID:16190898   PMID:16221859   PMID:16319310   PMID:16332682   PMID:16438943   PMID:16452087   PMID:16554481   PMID:16602821   PMID:16635246   PMID:16710293   PMID:16870468  
PMID:16899073   PMID:16901514   PMID:16944113   PMID:16971539   PMID:16987814   PMID:17010101   PMID:17045972   PMID:17054720   PMID:17105944   PMID:17114649   PMID:17229826   PMID:17234586  
PMID:17273929   PMID:17298852   PMID:17329427   PMID:17432968   PMID:17460065   PMID:17529984   PMID:17663722   PMID:17881524   PMID:17901118   PMID:17950729   PMID:17972914   PMID:18005003  
PMID:18057203   PMID:18077696   PMID:18082335   PMID:18197970   PMID:18301761   PMID:18331477   PMID:18339621   PMID:18372311   PMID:18380671   PMID:18423999   PMID:18603407   PMID:18624924  
PMID:18647646   PMID:18685090   PMID:18826591   PMID:18851757   PMID:18922769   PMID:18992939   PMID:19007751   PMID:19081379   PMID:19118186   PMID:19164281   PMID:19208628   PMID:19224577  
PMID:19240213   PMID:19243221   PMID:19261890   PMID:19298817   PMID:19332541   PMID:19409266   PMID:19439493   PMID:19446010   PMID:19455133   PMID:19474217   PMID:19485558   PMID:19640847  
PMID:19726645   PMID:19806658   PMID:19815434   PMID:20003379   PMID:20133015   PMID:20141836   PMID:20185686   PMID:20237287   PMID:20357110   PMID:20418887   PMID:20427654   PMID:20467438  
PMID:20661302   PMID:20696923   PMID:20722721   PMID:20824214   PMID:20831617   PMID:20871164   PMID:20921396   PMID:20923697   PMID:20927585   PMID:21106831   PMID:21118530   PMID:21144999  
PMID:21172391   PMID:21184813   PMID:21190942   PMID:21289476   PMID:21300867   PMID:21339379   PMID:21503117   PMID:21521616   PMID:21521618   PMID:21558424   PMID:21655294   PMID:21664258  
PMID:21677750   PMID:21685875   PMID:21704131   PMID:21762461   PMID:21795692   PMID:21804034   PMID:21814037   PMID:21873635   PMID:21880917   PMID:21943605   PMID:21945132   PMID:21955919  
PMID:21966384   PMID:22153375   PMID:22187052   PMID:22219357   PMID:22234183   PMID:22306487   PMID:22307082   PMID:22334046   PMID:22427672   PMID:22479519   PMID:22492045   PMID:22516462  
PMID:22523092   PMID:22536327   PMID:22558458   PMID:22565825   PMID:22572802   PMID:22723691   PMID:22723709   PMID:22740692   PMID:22820466   PMID:22855824   PMID:22902837   PMID:22909213  
PMID:22933778   PMID:22956849   PMID:22960607   PMID:23022271   PMID:23103165   PMID:23103326   PMID:23112146   PMID:23173822   PMID:23201971   PMID:23239421   PMID:23303941   PMID:23303946  
PMID:23332760   PMID:23618906   PMID:23674822   PMID:23760271   PMID:23831965   PMID:23852113   PMID:23866919   PMID:23871830   PMID:23884936   PMID:23892010   PMID:23902942   PMID:23904361  
PMID:23964123   PMID:24025330   PMID:24069373   PMID:24096375   PMID:24101472   PMID:24175101   PMID:24301649   PMID:24315834   PMID:24336715   PMID:24413569   PMID:24441682   PMID:24448406  
PMID:24584520   PMID:24607229   PMID:24687455   PMID:24690172   PMID:24725413   PMID:24734203   PMID:24836181   PMID:24952961   PMID:25128602   PMID:25131300   PMID:25151305   PMID:25158771  
PMID:25164652   PMID:25360708   PMID:25429143   PMID:25442114   PMID:25450957   PMID:25568101   PMID:25664912   PMID:25708312   PMID:25762721   PMID:25798630   PMID:25800971   PMID:25829490  
PMID:25896886   PMID:25916683   PMID:25968910   PMID:25979088   PMID:26027736   PMID:26041915   PMID:26085624   PMID:26118841   PMID:26179233   PMID:26203861   PMID:26204818   PMID:26223494  
PMID:26229100   PMID:26247728   PMID:26282667   PMID:26401567   PMID:26500840   PMID:26581639   PMID:26609151   PMID:26627310   PMID:26793056   PMID:26880306   PMID:26884337   PMID:26901155  
PMID:26931569   PMID:26932446   PMID:27015584   PMID:27059438   PMID:27170659   PMID:27179791   PMID:27246855   PMID:27325115   PMID:27422716   PMID:27457929   PMID:27480238   PMID:27507650  
PMID:27568557   PMID:27605622   PMID:27634008   PMID:27732941   PMID:27785460   PMID:27800545   PMID:27876882   PMID:27915379   PMID:27981829   PMID:28069946   PMID:28109345   PMID:28174113  
PMID:28244951   PMID:28358367   PMID:28359951   PMID:28452394   PMID:28456939   PMID:28614711   PMID:28671696   PMID:28682239   PMID:28688852   PMID:28706196   PMID:28834750   PMID:28864826  
PMID:28865018   PMID:28899992   PMID:28993251   PMID:29176858   PMID:29488136   PMID:29490264   PMID:29505785   PMID:29593052   PMID:29626166   PMID:29748616   PMID:29764972   PMID:29847800  
PMID:29982266   PMID:30104731   PMID:30269991   PMID:30352630   PMID:30355491   PMID:30466882   PMID:30471357   PMID:30504838   PMID:30562941   PMID:30742964   PMID:30946007   PMID:30992372  
PMID:31085626   PMID:31424425   PMID:31498792   PMID:31600191   PMID:31712124   PMID:31744842   PMID:31841517   PMID:31914378   PMID:32179753   PMID:32253239   PMID:32325033   PMID:32353004  
PMID:32710818   PMID:33068634  


Genomics

Comparative Map Data
Grin2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396135,690,219 - 136,150,658 (-)NCBIGRCm39mm39
GRCm39 Ensembl6135,690,231 - 136,150,509 (-)Ensembl
GRCm386135,713,221 - 136,173,615 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6135,713,233 - 136,173,511 (-)EnsemblGRCm38mm10GRCm38
MGSCv376135,679,813 - 136,123,529 (-)NCBIGRCm37mm9NCBIm37
MGSCv366135,697,791 - 136,009,994 (-)NCBImm8
Celera6138,678,301 - 139,123,902 (-)NCBICelera
Cytogenetic Map6G1NCBI
cM Map666.38NCBI
GRIN2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1213,437,942 - 13,981,957 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1213,437,942 - 13,982,002 (-)EnsemblGRCh38hg38GRCh38
GRCh381213,537,337 - 13,982,012 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371213,690,271 - 14,134,536 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361213,605,411 - 14,024,319 (-)NCBINCBI36hg18NCBI36
Build 341213,605,410 - 14,024,319NCBI
Celera1218,858,978 - 19,277,660 (-)NCBI
Cytogenetic Map12p13.1NCBI
HuRef1213,479,858 - 13,898,402 (-)NCBIHuRef
CHM1_11213,679,406 - 14,098,101 (-)NCBICHM1_1
Grin2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24168,580,824 - 169,044,110 (-)NCBI
Rnor_6.0 Ensembl4169,560,387 - 169,999,873 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04169,541,620 - 170,000,216 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04233,806,406 - 234,260,360 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44172,721,895 - 173,183,187 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14172,966,830 - 173,428,311 (-)NCBI
Celera4157,188,514 - 157,629,365 (-)NCBICelera
RH 3.4 Map41026.8RGD
Cytogenetic Map4q43NCBI
Grin2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541310,376,597 - 10,779,145 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541310,358,931 - 10,780,004 (-)NCBIChiLan1.0ChiLan1.0
GRIN2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11213,943,936 - 14,272,195 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1213,969,387 - 14,388,799 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01213,543,104 - 13,987,437 (-)NCBIMhudiblu_PPA_v0panPan3
GRIN2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12732,470,889 - 32,883,606 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2732,471,153 - 32,877,680 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2713,572,169 - 13,850,223 (-)NCBI
ROS_Cfam_1.02732,702,956 - 33,191,598 (+)NCBI
UMICH_Zoey_3.12732,798,882 - 33,078,120 (+)NCBI
UNSW_CanFamBas_1.02732,748,401 - 33,027,217 (+)NCBI
UU_Cfam_GSD_1.02713,302,777 - 13,581,228 (-)NCBI
Grin2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494593,677,907 - 94,094,419 (+)NCBI
SpeTri2.0NW_0049365873,406,055 - 3,806,956 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRIN2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl558,480,526 - 58,927,583 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1558,477,862 - 58,948,735 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2561,874,217 - 62,275,930 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GRIN2B
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11113,444,155 - 13,873,034 (-)NCBI
ChlSab1.1 Ensembl1113,456,968 - 13,873,202 (-)Ensembl
Grin2b
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475224,008,520 - 24,480,834 (+)NCBI

Position Markers
AW490526  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386135,730,149 - 135,730,245UniSTSGRCm38
MGSCv376135,680,167 - 135,680,263UniSTSGRCm37
Celera6138,678,639 - 138,678,735UniSTS
Cytogenetic Map6G1UniSTS
cM Map664.5UniSTS
Whitehead/MRC_RH61343.53UniSTS
RH94750  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386136,171,465 - 136,171,659UniSTSGRCm38
MGSCv376136,121,483 - 136,121,677UniSTSGRCm37
Celera6139,121,856 - 139,122,050UniSTS
Cytogenetic Map6G1UniSTS
cM Map664.5UniSTS
D6Mit301  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386136,045,041 - 136,045,152UniSTSGRCm38
MGSCv376135,995,059 - 135,995,170UniSTSGRCm37
Celera6138,996,609 - 138,996,724UniSTS
Cytogenetic Map6G1UniSTS
cM Map664.0UniSTS
Whitehead Genetic653.6UniSTS
Whitehead/MRC_RH61347.1UniSTS
Grin2b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386135,733,281 - 135,733,681UniSTSGRCm38
MGSCv376135,682,210 - 135,682,390UniSTSGRCm37
Celera6138,681,767 - 138,682,167UniSTS
Cytogenetic Map6G1UniSTS
cM Map664.5UniSTS
cM Map664.5UniSTS
ha3042  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38169,585,408 - 9,585,715UniSTSGRCm38
MGSCv37169,585,501 - 9,585,808UniSTSGRCm37
Celera1610,225,083 - 10,225,390UniSTS
Celera6139,069,596 - 139,070,459UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map6G1UniSTS
cM Map163.4UniSTS
cM Map664.5UniSTS
Grin2b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6G1UniSTS
Grin2b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386135,732,192 - 135,732,372UniSTSGRCm38
MGSCv376135,682,210 - 135,682,390UniSTSGRCm37
Celera6138,680,678 - 138,680,858UniSTS
Cytogenetic Map6G1UniSTS
cM Map664.5UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692607306146429238Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96655951146633626Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96655951146633626Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696655951146633626Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698506837145935444Mouse
1300887Pabr1_mplasma apolipoprotein B (human) regulator 1 (mouse)Not determined6103777444136423692Mouse
1357806Aaj3_manxiety in A/J 3 (mouse)Not determined6104503360136423692Mouse
10412207Cypr5_mcytokine production 5 (mouse)Not determined6110838217144838360Mouse
13463481Mcvq14_mmean corpuscular volume QTL 14 (mouse)6111165485145165578Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112269957147052561Mouse
4140980Mvwf2_mmodifier of von Willebrand factor 2 (mouse)Not determined114368732145656013Mouse
1301658Radpf3_mradiation pulmonary fibrosis 3 (mouse)Not determined6115242853146429238Mouse
4141194Cyx_mcycloheximide tasting (mouse)Not determined115569842149572401Mouse
4141889Qui_mquinine sensitivity, taste (mouse)Not determined115569842149572401Mouse
4141295Rua_mraffinose acetate tasting (mouse)Not determined115569842149572401Mouse
1301927Etohcta6_methanol conditioned taste aversion 6 (mouse)Not determined6115601042149601187Mouse
4142079Skmw15_mskeletal muscle weight 15 (mouse)Not determined6116852888149736546Mouse
1301152Athsq2_matherosclerosis susceptibility QTL 2 (mouse)Not determined6117082986149736546Mouse
1301804Bulb2_mbulb size 2 (mouse)Not determined6120439808149736546Mouse
10449436Pas17_mpulmonary adenoma susceptibility 17 (mouse)6124357314145656013Mouse
1302089Wta2_mweight adult 2 (mouse)Not determined6125323797149736546Mouse
10412134Cmv4_mcytomegalovirus resistance 4 (mouse)Not determined6127838217136045152Mouse
10449437Pas15_mpulmonary adenoma susceptibility 15 (mouse)6128235142149736546Mouse
4141151Ath38_matherosclerosis 38 (mouse)Not determined128518894136316178Mouse
1301027Hdlq12_mHDL QTL 12 (mouse)Not determined6128655856149736546Mouse
10053680Lith25_mlithogenic gene 25 (mouse)Not determined6128655856149736546Mouse
10766452Sle23_msystematic lupus erythematosus susceptibility 23 (mouse)6128655856149736546Mouse
10412215Cmv3_mcytomegalovirus resistance 3 (mouse)Not determined6128834894137439929Mouse
1301084Bpq5_mblood pressure QTL 5 (mouse)Not determined6129428986149736546Mouse
1301686Trmq1_mT cell ratio modifier QTL 1 (mouse)Not determined6129428986149736546Mouse
4141974Skmw14_mskeletal muscle weight 14 (mouse)Not determined6129428986149736546Mouse
1301620Insq8_minsulin QTL 8 (mouse)Not determined6129633481149736546Mouse
1558959Eamcd2_mexperimental autoimmune myocarditis 2 (mouse)Not determined6130052456149736546Mouse
14746990Manh61_mmandible shape 61 (mouse)6130254857149736546Mouse
14746999Mancz6_mmandible centroid size 6 (mouse)6130254857149736546Mouse
12879916Shm5_msperm head morphology 5 (mouse)6132289569145656013Mouse
1301820Mop1_mmorphine preference 1 (mouse)Not determined6132601042146429238Mouse
12910121Lvic3_mliver iron content 3 (mouse)6134119450136045152Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:7355
Count of miRNA genes:1026
Interacting mature miRNAs:1602
Transcripts:ENSMUST00000053880, ENSMUST00000111905, ENSMUST00000125905, ENSMUST00000143943, ENSMUST00000152012
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001363750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011241221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036165858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC124500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC124590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC132119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC161364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ459261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ459262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ459263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF745896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D10651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U60210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000053880   ⟹   ENSMUSP00000062284
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl6135,713,233 - 136,173,125 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111905   ⟹   ENSMUSP00000107536
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl6135,729,826 - 136,173,511 (-)Ensembl
RefSeq Acc Id: ENSMUST00000125905   ⟹   ENSMUSP00000139706
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl6136,044,196 - 136,173,511 (-)Ensembl
RefSeq Acc Id: ENSMUST00000143943   ⟹   ENSMUSP00000140710
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl6136,044,196 - 136,173,511 (-)Ensembl
RefSeq Acc Id: ENSMUST00000152012   ⟹   ENSMUSP00000142696
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl6135,869,703 - 136,173,511 (-)Ensembl
RefSeq Acc Id: ENSMUST00000188999   ⟹   ENSMUSP00000140452
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl6136,044,193 - 136,171,889 (-)Ensembl
RefSeq Acc Id: ENSMUST00000198283
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl6136,171,763 - 136,173,377 (-)Ensembl
RefSeq Acc Id: NM_001363750   ⟹   NP_001350679
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396135,690,219 - 136,150,543 (-)NCBI
GRCm386135,713,221 - 136,173,545 (-)NCBI
Sequence:
RefSeq Acc Id: NM_008171   ⟹   NP_032197
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396135,690,219 - 136,150,543 (-)NCBI
GRCm386135,713,221 - 136,173,545 (-)NCBI
MGSCv376135,679,813 - 136,123,529 (-)RGD
Celera6138,678,301 - 139,123,902 (-)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006505573   ⟹   XP_006505636
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396135,706,793 - 136,149,392 (-)NCBI
GRCm386135,730,072 - 136,172,259 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006505574   ⟹   XP_006505637
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396135,706,793 - 136,149,816 (-)NCBI
GRCm386135,730,072 - 136,172,818 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006505575   ⟹   XP_006505638
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396135,706,793 - 136,150,570 (-)NCBI
GRCm386135,730,072 - 136,173,546 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011241221   ⟹   XP_011239523
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396135,706,793 - 136,150,658 (-)NCBI
GRCm386135,730,072 - 136,173,615 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036165858   ⟹   XP_036021751
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396135,706,793 - 136,149,230 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_032197   ⟸   NM_008171
- Peptide Label: precursor
- UniProtKB: Q01097 (UniProtKB/Swiss-Prot),   G3X9V4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006505638   ⟸   XM_006505575
- Peptide Label: isoform X1
- UniProtKB: G3X9V4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006505637   ⟸   XM_006505574
- Peptide Label: isoform X1
- UniProtKB: G3X9V4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006505636   ⟸   XM_006505573
- Peptide Label: isoform X1
- UniProtKB: G3X9V4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011239523   ⟸   XM_011241221
- Peptide Label: isoform X1
- UniProtKB: G3X9V4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001350679   ⟸   NM_001363750
- Peptide Label: precursor
RefSeq Acc Id: ENSMUSP00000139706   ⟸   ENSMUST00000125905
RefSeq Acc Id: ENSMUSP00000107536   ⟸   ENSMUST00000111905
RefSeq Acc Id: ENSMUSP00000140710   ⟸   ENSMUST00000143943
RefSeq Acc Id: ENSMUSP00000142696   ⟸   ENSMUST00000152012
RefSeq Acc Id: ENSMUSP00000062284   ⟸   ENSMUST00000053880
RefSeq Acc Id: ENSMUSP00000140452   ⟸   ENSMUST00000188999
RefSeq Acc Id: XP_036021751   ⟸   XM_036165858
- Peptide Label: isoform X1
Protein Domains
ANF_receptor   Lig_chan-Glu_bd   PBPe

Promoters
RGD ID:6839422
Promoter ID:MM_KWN:48019
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:ENSMUST00000053880,   UC009ELR.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366136,122,241 - 136,122,741 (-)MPROMDB
RGD ID:6891398
Promoter ID:EPDNEW_M9113
Type:multiple initiation site
Name:Grin2b_1
Description:Mus musculus glutamate receptor, ionotropic, NMDA2B , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M9114  EPDNEW_M9115  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386136,171,843 - 136,171,903EPDNEW
RGD ID:6891326
Promoter ID:EPDNEW_M9114
Type:initiation region
Name:Grin2b_3
Description:Mus musculus glutamate receptor, ionotropic, NMDA2B , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M9115  EPDNEW_M9113  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386136,173,132 - 136,173,192EPDNEW
RGD ID:6891328
Promoter ID:EPDNEW_M9115
Type:initiation region
Name:Grin2b_2
Description:Mus musculus glutamate receptor, ionotropic, NMDA2B , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M9114  EPDNEW_M9113  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386136,173,502 - 136,173,562EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95821 AgrOrtholog
Ensembl Genes ENSMUSG00000030209 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000062284 UniProtKB/TrEMBL
  ENSMUSP00000107536 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000139706 UniProtKB/TrEMBL
  ENSMUSP00000140452 UniProtKB/TrEMBL
  ENSMUSP00000140710 UniProtKB/TrEMBL
  ENSMUSP00000142696 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000053880 UniProtKB/TrEMBL
  ENSMUST00000111905 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000125905 UniProtKB/TrEMBL
  ENSMUST00000143943 UniProtKB/TrEMBL
  ENSMUST00000152012 UniProtKB/TrEMBL
  ENSMUST00000188999 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glu/Gly-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Iono_rcpt_met UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Iontro_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NMDAR2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14812 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:95821 ENTREZGENE
NCBI Gene 14812 ENTREZGENE
Pfam ANF_receptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lig_chan UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lig_chan-Glu_bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NMDAR2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Grin2b PhenoGen
PRINTS NMDARECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Lig_chan-Glu_bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PBPe UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53822 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WR33_MOUSE UniProtKB/TrEMBL
  A0A0G2JEA7_MOUSE UniProtKB/TrEMBL
  G3X9V4 ENTREZGENE, UniProtKB/TrEMBL
  NMDE2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TR00_MOUSE UniProtKB/TrEMBL
  Q8CG67_MOUSE UniProtKB/TrEMBL
  Q8CG68_MOUSE UniProtKB/TrEMBL
  Q8CG69_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q9DCB2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-07 Grin2b  glutamate receptor, ionotropic, NMDA2B (epsilon 2)  AW490526  expressed sequence AW490526  Data Merged 737654 PROVISIONAL