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Gene: Mknk2 (MAP kinase-interacting serine/threonine kinase 2) Mus musculus
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Symbol: Mknk2
Name: MAP kinase-interacting serine/threonine kinase 2
Description: Exhibits ATP binding activity and protein serine/threonine kinase activity. Involved in extrinsic apoptotic signaling pathway in absence of ligand; intracellular signal transduction; and protein phosphorylation. Predicted to localize to the cytoplasm and nuclear body. Is expressed in several structures, including central nervous system; genitourinary system; neural retina; salivary gland; and spleen. Orthologous to human MKNK2 (MAPK interacting serine/threonine kinase 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2010016G11Rik; G protein-coupled receptor kinase 7; Gprk7; MAP kinase signal-integrating kinase 2; MAP kinase-interacting serine/threonine-protein kinase 2; MAPK signal-integrating kinase 2; Mnk2
Orthologs:
Homo sapiens (human) : MKNK2 (MAPK interacting serine/threonine kinase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mknk2 (MAPK interacting serine/threonine kinase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mknk2 (MAPK interacting serine/threonine kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MKNK2 (MAPK interacting serine/threonine kinase 2)
Canis lupus familiaris (dog) : MKNK2 (MAPK interacting serine/threonine kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mknk2 (MAPK interacting serine/threonine kinase 2)
Sus scrofa (pig) : MKNK2 (MAPK interacting serine/threonine kinase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381080,665,318 - 80,676,293 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371080,128,072 - 80,134,721 (-)NCBIGRCm37mm9NCBIm37
MGSCv361080,068,456 - 80,075,105 (-)NCBImm8
Celera1081,683,700 - 81,694,674 (-)NCBICelera
Cytogenetic Map10 C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Mknk2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313931
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.