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Gene: Mknk2 (MAP kinase-interacting serine/threonine kinase 2) Mus musculus
Symbol: Mknk2
Name: MAP kinase-interacting serine/threonine kinase 2
Description: Exhibits ATP binding activity and protein serine/threonine kinase activity. Involved in extrinsic apoptotic signaling pathway in absence of ligand; intracellular signal transduction; and protein phosphorylation. Predicted to localize to the cytoplasm and nuclear body. Is expressed in several structures, including central nervous system; genitourinary system; neural retina; salivary gland; and spleen. Orthologous to human MKNK2 (MAPK interacting serine/threonine kinase 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2010016G11Rik; G protein-coupled receptor kinase 7; Gprk7; MAP kinase signal-integrating kinase 2; MAP kinase-interacting serine/threonine-protein kinase 2; MAPK signal-integrating kinase 2; Mnk2
Homo sapiens (human) : MKNK2 (MAPK interacting serine/threonine kinase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mknk2 (MAPK interacting serine/threonine kinase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mknk2 (MAPK interacting serine/threonine kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MKNK2 (MAPK interacting serine/threonine kinase 2)
Canis lupus familiaris (dog) : MKNK2 (MAPK interacting serine/threonine kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mknk2 (MAPK interacting serine/threonine kinase 2)
Sus scrofa (pig) : MKNK2 (MAPK interacting serine/threonine kinase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381080,665,318 - 80,676,293 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371080,128,072 - 80,134,721 (-)NCBIGRCm37mm9NCBIm37
MGSCv361080,068,456 - 80,075,105 (-)NCBImm8
Celera1081,683,700 - 81,694,674 (-)NCBICelera
Cytogenetic Map10 C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Mknk2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313931
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.