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Gene: Crh (corticotropin releasing hormone) Mus musculus
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Symbol: Crh
Name: corticotropin releasing hormone
Description: This gene encodes a member of the corticotropin-releasing factor family and preproprotein that is proteolytically processed to generate a mature protein product. This protein product is a neuropeptide hormone that binds to the corticotropin releasing hormone receptors (CRHR1 and CRHR2) to stimulate the release of adrenocorticotropic hormone from the pituitary gland in response to stress. The encoded protein may also regulate angiogenesis and inflammation. Homozygous knockout mice for this gene exhibit reduced corticosterone levels while the offspring of these mice die perinatally. [provided by RefSeq, Aug 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: corticoliberin; corticotropin releasing factor; corticotropin-releasing factor; corticotropin-releasing hormone; CRF; Gm1347; MGC151298
Orthologs:
Homo sapiens (human) : CRH (corticotropin releasing hormone)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Crh (corticotropin releasing hormone)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Crh (corticotropin releasing hormone)
Pan paniscus (bonobo/pygmy chimpanzee) : CRH (corticotropin releasing hormone)
Canis lupus familiaris (dog) : CRH (corticotropin releasing hormone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crh (corticotropin releasing hormone)
Sus scrofa (pig) : CRH (corticotropin releasing hormone)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38319,693,401 - 19,695,396 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37319,593,401 - 19,595,396 (-)NCBIGRCm37mm9NCBIm37
MGSCv36319,885,565 - 19,887,480 (-)NCBImm8
Celera319,686,501 - 19,688,496 (-)NCBICelera
Cytogenetic Map3 A2NCBI
cM Map35.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Crh
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730947
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.