Gabrb1 (gamma-aminobutyric acid type A receptor subunit beta 1) - Rat Genome Database

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Gene: Gabrb1 (gamma-aminobutyric acid type A receptor subunit beta 1) Mus musculus
Analyze
Symbol: Gabrb1
Name: gamma-aminobutyric acid type A receptor subunit beta 1
RGD ID: 10611
MGI Page MGI
Description: Enables G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential. Predicted to be involved in several processes, including cellular response to histamine; chloride transmembrane transport; and gamma-aminobutyric acid signaling pathway. Is active in GABA-ergic synapse and Schaffer collateral - CA1 synapse. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in autistic disorder and developmental and epileptic encephalopathy 45. Orthologous to human GABRB1 (gamma-aminobutyric acid type A receptor subunit beta1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AW061132; B230208N19Rik; GABA(A) receptor subunit beta-1; GABAAR subunit beta-1; Gabrb; Gabrb-1; gamma-aminobutyric acid (GABA) A receptor, subunit beta 1; gamma-aminobutyric acid (GABA-A) receptor, subunit beta 1; gamma-aminobutyric acid receptor subunit beta-1; RIKEN cDNA B230208N19 gene
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39571,815,264 - 72,306,915 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl571,815,456 - 72,306,380 (+)EnsemblGRCm39 Ensembl
GRCm38571,657,921 - 72,149,572 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl571,658,113 - 72,149,037 (+)EnsemblGRCm38mm10GRCm38
MGSCv37572,091,255 - 72,528,483 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36571,979,151 - 72,416,379 (+)NCBIMGSCv36mm8
Celera568,964,933 - 69,390,319 (+)NCBICelera
Cytogenetic Map5C3.2NCBI
cM Map538.18NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-trichloroethane  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,2,2-trifluoroethanol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
3alpha-hydroxy-5beta-pregnan-20-one  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
androgen antagonist  (ISO)
aripiprazole  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bicuculline  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylparaben  (ISO)
chloral hydrate  (ISO)
Chloralose  (ISO)
chlorobutanol  (ISO)
cocaine  (ISO)
DDE  (ISO)
delta-hexachlorocyclohexane  (ISO)
dexamethasone  (ISO)
diazepam  (EXP,ISO)
dibutyl phthalate  (ISO)
dorsomorphin  (ISO)
endosulfan  (ISO)
enflurane  (ISO)
entinostat  (ISO)
enzacamene  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP,ISO)
ether  (ISO)
etomidate  (ISO)
felbamate  (ISO)
fipronil  (ISO)
flumazenil  (ISO)
flurotyl  (ISO)
folic acid  (EXP,ISO)
gamma-aminobutyric acid  (EXP,ISO)
gamma-hexachlorocyclohexane  (ISO)
genistein  (EXP)
glycidol  (ISO)
glyphosate  (EXP)
haloperidol  (ISO)
isoflurane  (ISO)
kainic acid  (EXP)
lead(0)  (ISO)
linuron  (ISO)
methimazole  (ISO)
methoxyflurane  (ISO)
muscimol  (ISO)
N,N-diethyl-m-toluamide  (ISO)
niclosamide  (ISO)
ozone  (EXP)
paracetamol  (ISO)
paraquat  (ISO)
pentobarbital  (EXP,ISO)
permethrin  (ISO)
picrotoxin  (ISO)
picrotoxinin  (ISO)
prochloraz  (ISO)
procymidone  (ISO)
progesterone  (ISO)
propofol  (ISO)
quercetin  (EXP)
SB 431542  (ISO)
sevoflurane  (ISO)
sodium arsenite  (EXP,ISO)
sulfadimethoxine  (ISO)
tert-butanol  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
tribromoethanol  (ISO)
trichloroethene  (ISO)
triptonide  (EXP)
valproic acid  (ISO)
venlafaxine hydrochloride  (ISO)
vinclozolin  (ISO)
zaleplon  (ISO)
zolpidem  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Investigation of autism and GABA receptor subunit genes in multiple ethnic groups. Collins AL, etal., Neurogenetics. 2006 Jul;7(3):167-74. Epub 2006 Jun 13.
2. mRNA and protein levels for GABAAalpha4, alpha5, beta1 and GABABR1 receptors are altered in brains from subjects with autism. Fatemi SH, etal., J Autism Dev Disord. 2010 Jun;40(6):743-50.
3. No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits. Kniazeff J, etal., J Neurosci 2002 Sep 1;22(17):7352-61.
4. Expression of gamma-aminobutyric acid A receptor subunits alpha1, beta1, gamma2 mRNA in rats with hepatic encephalopathy. Li XQ, etal., World J Gastroenterol. 2005 Jun 7;11(21):3319-22.
5. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1282920   PMID:1321150   PMID:2561974   PMID:7542761   PMID:7579892   PMID:7893750   PMID:8390964   PMID:8589683   PMID:8889548   PMID:10349636   PMID:10447508   PMID:10843805  
PMID:10899153   PMID:10949077   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11331379   PMID:11498050   PMID:11528422   PMID:12097484   PMID:12477932   PMID:14610273   PMID:14681479  
PMID:15755515   PMID:16141072   PMID:16141073   PMID:16987237   PMID:17698926   PMID:17953485   PMID:18336815   PMID:18667494   PMID:18985723   PMID:20159020   PMID:20511229   PMID:21267068  
PMID:21677750   PMID:21735059   PMID:21873635   PMID:22534482   PMID:22723691   PMID:22768092   PMID:22879594   PMID:23176253   PMID:24194600   PMID:24281383   PMID:24952961   PMID:25479464  
PMID:25708312   PMID:25979088   PMID:26518330   PMID:28489004   PMID:29706582   PMID:31138677   PMID:32484592   PMID:33942407   PMID:34321999   PMID:36417873   PMID:38187761   PMID:38355793  
PMID:38876310  


Genomics

Comparative Map Data
Gabrb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39571,815,264 - 72,306,915 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl571,815,456 - 72,306,380 (+)EnsemblGRCm39 Ensembl
GRCm38571,657,921 - 72,149,572 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl571,658,113 - 72,149,037 (+)EnsemblGRCm38mm10GRCm38
MGSCv37572,091,255 - 72,528,483 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36571,979,151 - 72,416,379 (+)NCBIMGSCv36mm8
Celera568,964,933 - 69,390,319 (+)NCBICelera
Cytogenetic Map5C3.2NCBI
cM Map538.18NCBI
GABRB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38446,993,647 - 47,426,447 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl446,993,723 - 47,426,447 (+)EnsemblGRCh38hg38GRCh38
GRCh37447,033,584 - 47,428,464 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36446,728,336 - 47,123,202 (+)NCBINCBI36Build 36hg18NCBI36
Build 34446,874,506 - 47,269,373NCBI
Celera447,482,542 - 47,877,035 (+)NCBICelera
Cytogenetic Map4p12NCBI
HuRef446,352,751 - 46,747,922 (+)NCBIHuRef
CHM1_1447,032,490 - 47,427,496 (+)NCBICHM1_1
T2T-CHM13v2.0446,998,964 - 47,393,806 (+)NCBIT2T-CHM13v2.0
Gabrb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81436,434,339 - 36,917,920 (-)NCBIGRCr8
mRatBN7.21436,068,725 - 36,548,946 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1436,080,393 - 36,548,948 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1436,416,572 - 36,894,556 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01437,721,331 - 38,199,312 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01436,209,655 - 36,687,660 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01438,631,192 - 39,112,598 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1438,643,385 - 39,112,600 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01438,453,142 - 38,924,073 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41438,530,259 - 39,005,615 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11438,532,649 - 39,008,000 (-)NCBI
Celera1435,310,585 - 35,771,142 (-)NCBICelera
Cytogenetic Map14p11NCBI
Gabrb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554431,132,860 - 1,514,376 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554431,126,223 - 1,514,291 (-)NCBIChiLan1.0ChiLan1.0
GABRB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2380,428,758 - 80,876,408 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1480,688,929 - 81,138,103 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0474,727,321 - 75,164,407 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1485,458,810 - 85,894,427 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl485,459,225 - 85,857,321 (-)Ensemblpanpan1.1panPan2
GABRB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11343,011,491 - 43,349,876 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1342,992,569 - 43,349,923 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1342,942,633 - 43,300,315 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01343,598,384 - 43,955,432 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1343,598,012 - 43,955,599 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11343,276,378 - 43,634,632 (+)NCBIUMICH_Zoey_3.1
UU_Cfam_GSD_1.01343,691,479 - 44,049,754 (+)NCBIUU_Cfam_GSD_1.0
Gabrb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528532,699,565 - 33,078,224 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648213,220,236 - 13,586,209 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648213,219,962 - 13,593,868 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GABRB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl836,978,547 - 37,355,008 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1836,978,014 - 37,354,950 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2839,176,670 - 39,275,449 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GABRB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1272,829,385 - 3,254,292 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl272,832,450 - 3,217,326 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604748,873,122 - 49,316,579 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gabrb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476119,600,946 - 20,017,278 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476119,595,802 - 20,019,368 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gabrb1
23048 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:901
Count of miRNA genes:491
Interacting mature miRNAs:582
Transcripts:ENSMUST00000031122
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301843Listr1_mlisteriosis resistance 1 (mouse)Not determined56024608194246203Mouse
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined32133234100777931Mouse
1301010ahl2_mage related hearing loss 2 (mouse)Not determined56265056896650688Mouse
11041899Lmr24a_mleishmaniasis resistance 24a (mouse)552694462107321041Mouse
1300951Gbvq1_mgallstone bladder volume QTL 1 (mouse)Not determined53811168172111798Mouse
14746981Manh57_mmandible shape 57 (mouse)54716974281169742Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537581488112465722Mouse
10045972Tir5_mtrypanosome infection response 5 (mouse)Not determined563705442104387065Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
1301698Pcfm4_mperiosteal circumference and femur length 4 (mouse)Not determined54458584378585965Mouse
4142317Rgcs1_mretinal ganglion cell susceptible 1 (mouse)Not determined55388334108762627Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined32133234100777931Mouse
12904740M1fscn2_mmodifier 1 of Fscn2 (mouse)566529661100529661Mouse
10043962Obq27_mobesity QTL 27 (mouse)Not determined55628565590285655Mouse
4142428Modvl1_mmodifier of vacuolated lens 1 (mouse)Not determined6265056896650688Mouse
11040589Lmr3a_mleishmaniasis resistance 3a (mouse)55960280193602980Mouse
11040590Lmr3b_mleishmaniasis resistance 3b (mouse)55960280193602980Mouse
11040591Lmr3c_mleishmaniasis resistance 3c (mouse)55960280193602980Mouse
12904739M2fscn2_mmodifier 2 of FSCN2 (mouse)566529661100529661Mouse
1301243Bmd2_mbone mineral density 2 (mouse)Not determined555388334100455525Mouse
13207584Mwmlpt4_mMorris water maze latency to platform, training, 4 (mouse)54632260680322606Mouse
11041665Lmr24_mleishmaniasis resistance 24 (mouse)552694462107321041Mouse
13207588Mwmlpa4_mMorris water maze latency to platform, all, 4 (mouse)54632260680322606Mouse
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5889069387841837Mouse
11049560Lmr24d_mleishmaniasis resistance 24d (mouse)56437487798374996Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
13464248Ahl13_mage related hearing loss, early onset 13 (mouse)55564587489645995Mouse
11252124Modvl6_mmodifier of vacuolated lens 6 (mouse)56265056896650688Mouse
13464250Ahl15_mage related hearing loss, early onset 15 (mouse)56265056896650688Mouse
13464245Ahl12_mage related hearing loss, early onset 12 (mouse)53811168172111798Mouse
11040592Lmr3d_mleishmaniasis resistance 3d (mouse)55960280193602980Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
13464247Ahl14_mage related hearing loss, early onset 14 (mouse)56040306294403160Mouse
10044005Ahl7_mage related hearing loss 7 (mouse)Not determined55833050292330641Mouse

Markers in Region
AW061132  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38572,136,736 - 72,136,855UniSTSGRCm38
MGSCv37572,527,975 - 72,528,094UniSTSGRCm37
Celera569,389,811 - 69,389,930UniSTS
Cytogenetic Map5C3.2UniSTS
Whitehead/MRC_RH5917.48UniSTS
U14418  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38572,136,870 - 72,137,029UniSTSGRCm38
MGSCv37572,528,109 - 72,528,268UniSTSGRCm37
Celera569,389,945 - 69,390,104UniSTS
Cytogenetic Map5C3.2UniSTS
Whitehead/MRC_RH5917.17UniSTS
Whitehead_YAC5 UniSTS
MHAa52c10.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38571,970,359 - 71,970,549UniSTSGRCm38
MGSCv37572,361,598 - 72,361,788UniSTSGRCm37
Celera569,231,524 - 69,231,714UniSTS
Cytogenetic Map5C3.2UniSTS
Whitehead_YAC5 UniSTS
D5Mit355  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38571,895,202 - 71,895,305UniSTSGRCm38
MGSCv37572,286,441 - 72,286,544UniSTSGRCm37
Celera569,156,176 - 69,156,291UniSTS
Cytogenetic Map5C3.2UniSTS
cM Map536.0UniSTS
Whitehead Genetic526.2UniSTS
Whitehead_YAC5 UniSTS
Gabrb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38572,136,502 - 72,137,206UniSTSGRCm38
MGSCv37572,527,741 - 72,528,445UniSTSGRCm37
Celera569,389,577 - 69,390,281UniSTS
Cytogenetic Map5C3.2UniSTS
cM Map1041.8UniSTS
cM Map540.0UniSTS
RH109435  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38572,136,901 - 72,137,134UniSTSGRCm38
MGSCv37572,528,140 - 72,528,373UniSTSGRCm37
Celera569,389,976 - 69,390,209UniSTS
Cytogenetic Map5C3.2UniSTS
cM Map540.0UniSTS
RH126116  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38571,987,500 - 71,987,720UniSTSGRCm38
MGSCv37572,378,739 - 72,378,959UniSTSGRCm37
Celera569,248,150 - 69,248,370UniSTS
Cytogenetic Map5C3.2UniSTS
Whitehead/MRC_RH5924.33UniSTS
D5Buc46  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38571,804,342 - 71,804,599UniSTSGRCm38
MGSCv37572,195,581 - 72,195,838UniSTSGRCm37
Celera569,069,091 - 69,069,348UniSTS
Cytogenetic Map5C3.2UniSTS
cM Map5 UniSTS
D5Buc28  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38572,082,374 - 72,082,629UniSTSGRCm38
MGSCv37572,473,613 - 72,473,868UniSTSGRCm37
Celera569,336,168 - 69,336,423UniSTS
Cytogenetic Map5C3.2UniSTS
cM Map540.0UniSTS
D5Buc32  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38572,126,624 - 72,126,809UniSTSGRCm38
MGSCv37572,517,863 - 72,518,048UniSTSGRCm37
Celera569,379,698 - 69,379,883UniSTS
Cytogenetic Map5C3.2UniSTS
cM Map540.0UniSTS
D5Buc33  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38572,127,909 - 72,128,172UniSTSGRCm38
MGSCv37572,519,148 - 72,519,411UniSTSGRCm37
Celera569,380,983 - 69,381,246UniSTS
Cytogenetic Map5C3.2UniSTS
cM Map540.0UniSTS
D5Buc34  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38572,097,304 - 72,097,551UniSTSGRCm38
MGSCv37572,488,543 - 72,488,790UniSTSGRCm37
Celera569,351,083 - 69,351,330UniSTS
Cytogenetic Map5C3.2UniSTS
cM Map540.0UniSTS
D5Buc37  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38571,937,624 - 71,937,798UniSTSGRCm38
MGSCv37572,328,863 - 72,329,037UniSTSGRCm37
Celera569,198,693 - 69,198,867UniSTS
Cytogenetic Map5C3.2UniSTS
cM Map540.0UniSTS
D5Buc35  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38571,962,875 - 71,963,070UniSTSGRCm38
MGSCv37572,354,114 - 72,354,309UniSTSGRCm37
Celera569,224,040 - 69,224,235UniSTS
Cytogenetic Map5C3.2UniSTS
cM Map540.0UniSTS
D5Buc38  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38571,937,438 - 71,937,738UniSTSGRCm38
MGSCv37572,328,677 - 72,328,977UniSTSGRCm37
Celera569,198,507 - 69,198,807UniSTS
Cytogenetic Map5C3.2UniSTS
cM Map540.0UniSTS
Gabrb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381078,181,145 - 78,181,583UniSTSGRCm38
MGSCv371077,643,890 - 77,644,328UniSTSGRCm37
Cytogenetic Map5C3.2UniSTS
Cytogenetic Map10C1UniSTS
cM Map540.0UniSTS
Gabrb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5C3.2UniSTS
U14418  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38572,136,917 - 72,137,033UniSTSGRCm38
MGSCv37572,528,156 - 72,528,272UniSTSGRCm37
Celera569,389,992 - 69,390,108UniSTS
Cytogenetic Map5C3.2UniSTS
Whitehead/MRC_RH5917.17UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000031122   ⟹   ENSMUSP00000031122
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl571,857,275 - 72,306,380 (+)Ensembl
GRCm38.p6 Ensembl571,699,932 - 72,149,037 (+)Ensembl
Ensembl Acc Id: ENSMUST00000199967   ⟹   ENSMUSP00000143682
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl571,815,456 - 72,266,122 (+)Ensembl
GRCm38.p6 Ensembl571,658,113 - 72,108,779 (+)Ensembl
RefSeq Acc Id: NM_001370968   ⟹   NP_001357897
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39571,815,264 - 72,306,915 (+)NCBI
GRCm38571,657,921 - 72,149,572 (+)NCBI
Sequence:
RefSeq Acc Id: NM_008069   ⟹   NP_032095
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39571,857,275 - 72,306,915 (+)NCBI
GRCm38571,699,932 - 72,149,572 (+)NCBI
MGSCv37572,091,255 - 72,528,483 (+)RGD
Celera568,964,933 - 69,390,319 (+)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032095   ⟸   NM_008069
- Peptide Label: isoform 1 precursor
- UniProtKB: P50571 (UniProtKB/Swiss-Prot),   Q53WT3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001357897   ⟸   NM_001370968
- Peptide Label: isoform 2
Ensembl Acc Id: ENSMUSP00000031122   ⟸   ENSMUST00000031122
Ensembl Acc Id: ENSMUSP00000143682   ⟸   ENSMUST00000199967
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P50571-F1-model_v2 AlphaFold P50571 1-474 view protein structure

Promoters
RGD ID:6886842
Promoter ID:EPDNEW_M6872
Type:initiation region
Name:Gabrb1_1
Description:Mus musculus gamma-aminobutyric acid A receptor, subunit beta1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38571,699,966 - 71,700,026EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95619 AgrOrtholog
Ensembl Genes ENSMUSG00000029212 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000031122 ENTREZGENE
  ENSMUST00000031122.9 UniProtKB/Swiss-Prot
  ENSMUST00000199967.5 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.390 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.70.170.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GABAA/Glycine_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GABAAb_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_lig-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_channel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neuro-gated_channel_TM_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neuro_actylchol_rec UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurotrans-gated_channel_TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurotransmitter_ion_chnl_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14400 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:95619 ENTREZGENE
NCBI Gene 14400 ENTREZGENE
PANTHER GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR18945 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Neur_chan_LBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_memb UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gabrb1 PhenoGen
PRINTS GABAARBETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GABAARECEPTR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NRIONCHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NEUROTR_ION_CHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF63712 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF90112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JGS8_MOUSE UniProtKB/TrEMBL
  GBRB1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q53WT3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-07-04 Gabrb1  gamma-aminobutyric acid type A receptor subunit beta 1  Gabrb1  gamma-aminobutyric acid (GABA) A receptor, subunit beta 1  Symbol and/or name change 5135510 APPROVED
2016-03-29 Gabrb1  gamma-aminobutyric acid (GABA) A receptor, subunit beta 1  B230208N19Rik  RIKEN cDNA B230208N19 gene  Data merged from RGD:1611529 737654 PROVISIONAL