Ap3b1 (adaptor-related protein complex 3, beta 1 subunit) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Ap3b1 (adaptor-related protein complex 3, beta 1 subunit) Mus musculus
Analyze
Symbol: Ap3b1
Name: adaptor-related protein complex 3, beta 1 subunit
RGD ID: 1321052
MGI Page MGI
Description: Predicted to enable GTP-dependent protein binding activity and protein phosphatase binding activity. Involved in anterograde synaptic vesicle transport. Acts upstream of with a positive effect on positive regulation of transcription by RNA polymerase II. Acts upstream of or within with a negative effect on mRNA transcription by RNA polymerase II and regulation of catalytic activity. Acts upstream of or within several processes, including establishment of protein localization to organelle; hemopoiesis; and vesicle organization. Is active in microvesicle. Used to study Hermansky-Pudlak syndrome 2 and platelet storage pool deficiency. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome; Hermansky-Pudlak syndrome 2; interstitial lung disease; neutropenia; and pulmonary fibrosis. Orthologous to human AP3B1 (adaptor related protein complex 3 subunit beta 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: adapter-related protein complex 3 subunit beta-1; adaptor protein complex AP-3 beta-1 subunit; adaptor protein complex AP-3 subunit beta-1; adaptor-related protein complex 3 subunit beta-1; adaptor-related protein complex AP-3 beta 1 subunit; adaptor-related protein complex AP-3, beta 1 subunit; AP; AP-3; AP-3 complex subunit beta-1; AU015684; beta-3A-adaptin; beta3A; beta3A-adaptin; C78395; clathrin assembly protein complex 3 beta-1 large chain; Hp; Hps2; pe; pearl; recombination induced mutation 2; ri; rim2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391394,492,332 - 94,702,838 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1394,495,468 - 94,702,825 (+)EnsemblGRCm39 Ensembl
GRCm381394,358,960 - 94,566,316 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1394,358,960 - 94,566,317 (+)EnsemblGRCm38mm10GRCm38
MGSCv371395,128,915 - 95,336,271 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361395,459,730 - 95,667,014 (+)NCBIMGSCv36mm8
Celera1397,976,815 - 98,179,412 (+)NCBICelera
Cytogenetic Map13C3NCBI
cM Map1349.22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal blood coagulation  (IAGP)
abnormal coat/hair pigmentation  (IAGP)
abnormal enzyme/coenzyme activity  (IAGP)
abnormal enzyme/coenzyme level  (IAGP)
abnormal eye movement  (IAGP)
abnormal eye pigmentation  (IAGP)
abnormal foot pigmentation  (IEA)
abnormal forebrain morphology  (IAGP)
abnormal lateral geniculate nucleus morphology  (IAGP)
abnormal lung epithelium morphology  (IAGP)
abnormal lung hysteresivity  (IAGP)
abnormal lung interstitium morphology  (IAGP)
abnormal lysosome morphology  (IAGP)
abnormal maternal nurturing  (IEA)
abnormal melanosome morphology  (IAGP)
abnormal midbrain roof plate morphology  (IAGP)
abnormal mineral homeostasis  (IAGP)
abnormal monocyte morphology  (IAGP)
abnormal nervous system physiology  (IAGP)
abnormal optic tract morphology  (IAGP)
abnormal platelet activation  (IAGP)
abnormal platelet dense granule morphology  (IAGP)
abnormal platelet dense granule physiology  (IAGP)
abnormal proximal convoluted tubule morphology  (IAGP)
abnormal pulmonary alveolus morphology  (IAGP)
abnormal skin pigmentation  (IEA)
abnormal superior colliculus morphology  (IAGP)
abnormal type II pneumocyte morphology  (IAGP)
abnormal vision  (IAGP)
abnormal visual cortex morphology  (IAGP)
accumulation of giant lysosomes in kidney/renal tubule cells  (IAGP)
anophthalmia  (IAGP)
cataract  (IAGP)
decreased ear pigmentation  (IEA)
decreased eye pigmentation  (IAGP)
decreased litter size  (IAGP)
decreased lysosomal enzyme secretion  (IAGP)
decreased platelet ADP level  (IAGP)
decreased platelet aggregation  (IAGP)
decreased platelet ATP level  (IAGP)
decreased platelet dense granule number  (IAGP)
decreased platelet serotonin level  (IAGP)
decreased tail pigmentation  (IEA)
diluted coat color  (IAGP)
emphysema  (IAGP)
enlarged alveolar lamellar bodies  (IAGP)
female infertility  (IEA)
hypopigmentation  (IAGP)
increased bleeding time  (IAGP)
increased lung weight  (IAGP)
increased susceptibility to Herpesvirales infection  (IEA)
lung hemorrhage  (IAGP)
lung inflammation  (IAGP)
neonatal lethality, incomplete penetrance  (IEA)
overexpanded pulmonary alveolus  (IAGP)
postnatal lethality  (IEA)
pregnancy-related premature death  (IEA)
premature death  (IAGP)
short uterine horn  (IAGP)
small uterus  (IAGP)
thin endometrium  (IAGP)
thin uterine horn  (IAGP)
uterus hypoplasia  (IAGP)
white spotting  (IEA)
References

References - curated
# Reference Title Reference Citation
1. The Hermansky-Pudlak syndrome 1 (HPS1) and HPS2 genes independently contribute to the production and function of platelet dense granules, melanosomes, and lysosomes. Feng L, etal., Blood. 2002 Mar 1;99(5):1651-8.
2. Genomic structure of the mouse Ap3b1 gene in normal and pearl mice. Feng L, etal., Genomics. 2000 Nov 1;69(3):370-9.
3. Interstitial lung disease and pulmonary fibrosis in Hermansky-Pudlak syndrome type 2, an adaptor protein-3 complex disease. Gochuico BR, etal., Mol Med. 2012 Feb 10;18:56-64. doi: 10.2119/molmed.2011.00198.
4. Disorders of vesicles of lysosomal lineage: the Hermansky-Pudlak syndromes. Huizing M and Gahl WA, Curr Mol Med. 2002 Aug;2(5):451-67.
5. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. MGD IEA MGD IEA
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:115747   PMID:1303230   PMID:1682216   PMID:1936982   PMID:3516713   PMID:3584547   PMID:4031460   PMID:5367369   PMID:6062373   PMID:6279728   PMID:6600521   PMID:6696991  
PMID:6735643   PMID:6971254   PMID:7310489   PMID:7719021   PMID:8449493   PMID:8661713   PMID:8828042   PMID:8830098   PMID:9151686   PMID:9434937   PMID:9545220   PMID:9714600  
PMID:9931340   PMID:10037816   PMID:10193444   PMID:10349636   PMID:10381507   PMID:10922068   PMID:10930456   PMID:11041359   PMID:11042159   PMID:11058094   PMID:11076861   PMID:11217851  
PMID:11544199   PMID:11588176   PMID:11836498   PMID:12445206   PMID:12466851   PMID:12477932   PMID:12520002   PMID:12777251   PMID:12904583   PMID:14530337   PMID:14557411   PMID:14610273  
PMID:15489334   PMID:15492041   PMID:15537701   PMID:15741177   PMID:15782199   PMID:15790974   PMID:16002709   PMID:16141072   PMID:16141073   PMID:16547274   PMID:16760431   PMID:16788073  
PMID:17287392   PMID:17349999   PMID:17363777   PMID:17967808   PMID:18410487   PMID:18554297   PMID:18629000   PMID:19010779   PMID:19144828   PMID:19401467   PMID:19737878   PMID:19934039  
PMID:20847273   PMID:21045126   PMID:21224474   PMID:21392365   PMID:21677750   PMID:21873635   PMID:21908583   PMID:21940780   PMID:21998198   PMID:22560444   PMID:22611153   PMID:23043085  
PMID:23219390   PMID:23247405   PMID:23364476   PMID:23403622   PMID:23748140   PMID:24086151   PMID:24457600   PMID:25160823   PMID:25333950   PMID:25477496   PMID:25673877   PMID:26423153  
PMID:26719147   PMID:26907692   PMID:27392064   PMID:27777976   PMID:28468798   PMID:28607399   PMID:29055005   PMID:29190429   PMID:30131424   PMID:30457570   PMID:30786955   PMID:31272455  
PMID:32016796   PMID:32249787   PMID:32325033   PMID:33513603   PMID:33557836   PMID:33990468   PMID:34995475   PMID:35349343   PMID:36114006   PMID:37142655   PMID:37723322   PMID:37812725  


Genomics

Comparative Map Data
Ap3b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391394,492,332 - 94,702,838 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1394,495,468 - 94,702,825 (+)EnsemblGRCm39 Ensembl
GRCm381394,358,960 - 94,566,316 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1394,358,960 - 94,566,317 (+)EnsemblGRCm38mm10GRCm38
MGSCv371395,128,915 - 95,336,271 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361395,459,730 - 95,667,014 (+)NCBIMGSCv36mm8
Celera1397,976,815 - 98,179,412 (+)NCBICelera
Cytogenetic Map13C3NCBI
cM Map1349.22NCBI
AP3B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38578,000,522 - 78,294,698 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl577,991,640 - 78,294,762 (-)EnsemblGRCh38hg38GRCh38
GRCh37577,296,346 - 77,590,522 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36577,333,906 - 77,626,284 (-)NCBINCBI36Build 36hg18NCBI36
Build 34577,333,906 - 77,626,284NCBI
Celera573,192,009 - 73,483,332 (-)NCBICelera
Cytogenetic Map5q14.1NCBI
HuRef572,504,871 - 72,797,261 (-)NCBIHuRef
CHM1_1576,732,015 - 77,024,021 (-)NCBICHM1_1
T2T-CHM13v2.0578,482,312 - 78,776,325 (-)NCBIT2T-CHM13v2.0
Ap3b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8227,331,241 - 27,535,683 (+)NCBIGRCr8
mRatBN7.2225,600,069 - 25,800,937 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl225,600,040 - 25,800,935 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx232,628,825 - 32,828,969 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0230,729,080 - 30,929,207 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0225,553,041 - 25,753,147 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0224,022,815 - 24,227,522 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl224,024,791 - 24,226,224 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0243,195,152 - 43,397,102 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4224,670,078 - 24,872,770 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1224,557,732 - 24,793,137 (+)NCBI
Celera221,672,156 - 21,872,572 (+)NCBICelera
Cytogenetic Map2q12NCBI
Ap3b1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542522,792,616 - 23,051,737 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542522,792,616 - 23,051,509 (+)NCBIChiLan1.0ChiLan1.0
AP3B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2437,008,432 - 37,299,817 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1535,163,000 - 35,453,444 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0537,015,518 - 37,305,769 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1537,502,986 - 37,835,904 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl537,503,162 - 37,840,205 (+)Ensemblpanpan1.1panPan2
AP3B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1328,481,974 - 28,748,095 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl328,481,038 - 28,751,258 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha329,722,995 - 29,988,777 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0328,405,848 - 28,672,345 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl328,405,824 - 28,675,022 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1328,341,769 - 28,607,713 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0328,320,012 - 28,585,750 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0328,647,884 - 28,914,348 (+)NCBIUU_Cfam_GSD_1.0
Ap3b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213184,654,420 - 184,894,394 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365495,965,143 - 6,204,379 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365495,964,240 - 6,205,245 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AP3B1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl286,873,290 - 87,142,768 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1286,875,922 - 87,142,722 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2288,534,908 - 88,719,584 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AP3B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1472,225,658 - 72,524,971 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl472,225,599 - 72,524,933 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604921,065,319 - 21,365,237 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ap3b1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248692,459,947 - 2,741,328 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248692,459,370 - 2,741,529 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ap3b1
6945 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:208
Count of miRNA genes:166
Interacting mature miRNAs:181
Transcripts:ENSMUST00000022196
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558741Ses10_msalmonella enteritidis susceptibility 10 (mouse)Not determined1382739968116740106Mouse
12879495Fexq1_mfear expression QTL 1 (mouse)137826885895836553Mouse
10043997Bw40_mbody weight QTL 40 (mouse)Not determined1479239045113239162Mouse
1301142Heal2_mwound healing/regeneration 2 (mouse)Not determined1393875267120883175Mouse
1301593Heal8_mwound healing/regeneration 8 (mouse)Not determined1368053999102054119Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
1301445Listr2_mlisteriosis resistance 2 (mouse)Not determined1366744601100744746Mouse
12880402Emlq1_memotional learning QTL 1 (mouse)137810885896866553Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
1300939Hrtfm6_mheart failure modifier 6 (mouse)Not determined1391383692120883175Mouse
12880414V125Dq10_mvitamin D active form serum level QTL 10 (mouse)1378036508112036508Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse
1300941Skl6_mskeletal size (tail length) 6 (mouse)Not determined136425082198250945Mouse
14747007Mancz11_mmandible centroid size 11 (mouse)1370111284104111284Mouse
4141728Egaq4_mearly growth adjusted QTL 4 (mouse)Not determined87901985112431103Mouse
1300876Tanidd2_mtally ho associated non-insulin dependednt diabetes mellitus 2 (mouse)Not determined1391965303120883175Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
1357553Cia28_mcollagen induced arthritis 28 (mouse)Not determined135662924996239162Mouse
4141266Mol3_mmodifier of LPS-response 3 (mouse)Not determined76132600112431103Mouse
1301949Skull20_mskull morphology 20 (mouse)Not determined136425082198250945Mouse
10045623Heal18_mwound healing regeneration 18 (mouse)Not determined1379239045113239162Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356470456105422186Mouse
14700691Cisaq1_mcoxsackieviral infection serum ALT QTL 1 (mouse)1386148119120461536Mouse
14696726Kidrq3_mkidney weight, right QTL 3 (mouse)1368217066102217066Mouse
1301610Dps1_mdelta power in slow-wave sleep 1 (mouse)Not determined137719586295730894Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
4140995Fbtq6_mfemoral bone trait QTL 6 (mouse)Not determined1386341617120341758Mouse
4142338Skmw18_mskeletal muscle weight 18 (mouse)Not determined1394528399120883175Mouse
4142465Pbwg17_mpostnatal body weight growth 17 (mouse)Not determined1383876060117876256Mouse

Markers in Region
AU015684  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381394,547,601 - 94,547,846UniSTSGRCm38
MGSCv371395,317,556 - 95,317,801UniSTSGRCm37
Celera1398,167,065 - 98,167,310UniSTS
Cytogenetic Map13D1UniSTS
cM Map1347.0UniSTS
Whitehead/MRC_RH13806.78UniSTS
C78395  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381394,565,770 - 94,565,920UniSTSGRCm38
MGSCv371395,335,725 - 95,335,875UniSTSGRCm37
Celera1398,178,866 - 98,179,016UniSTS
Cytogenetic Map13D1UniSTS
cM Map1347.0UniSTS
Whitehead/MRC_RH13819.75UniSTS
D13Mit299  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381394,465,783 - 94,465,930UniSTSGRCm38
MGSCv371395,235,738 - 95,235,885UniSTSGRCm37
Celera1398,085,247 - 98,085,376UniSTS
Cytogenetic Map13D1UniSTS
cM Map13 UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006517523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001780749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004937934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_382728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC122373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC123043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF103809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF267848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH009888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ032961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK129787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000022196   ⟹   ENSMUSP00000022196
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1394,495,468 - 94,702,825 (+)Ensembl
GRCm38.p6 Ensembl1394,358,960 - 94,566,317 (+)Ensembl
Ensembl Acc Id: ENSMUST00000220505
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1394,678,811 - 94,684,375 (+)Ensembl
GRCm38.p6 Ensembl1394,542,303 - 94,547,867 (+)Ensembl
Ensembl Acc Id: ENSMUST00000221206
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1394,668,514 - 94,702,191 (+)Ensembl
GRCm38.p6 Ensembl1394,532,006 - 94,565,683 (+)Ensembl
Ensembl Acc Id: ENSMUST00000222383
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1394,664,847 - 94,680,829 (+)Ensembl
GRCm38.p6 Ensembl1394,528,339 - 94,544,321 (+)Ensembl
Ensembl Acc Id: ENSMUST00000231916   ⟹   ENSMUSP00000155984
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1394,609,371 - 94,702,821 (+)Ensembl
GRCm38.p6 Ensembl1394,472,863 - 94,566,313 (+)Ensembl
RefSeq Acc Id: NM_009680   ⟹   NP_033810
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391394,495,468 - 94,702,824 (+)NCBI
GRCm381394,358,960 - 94,566,316 (+)NCBI
MGSCv371395,128,915 - 95,336,271 (+)RGD
Celera1397,976,815 - 98,179,412 (+)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006517523   ⟹   XP_006517586
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391394,492,332 - 94,702,838 (+)NCBI
GRCm381394,358,966 - 94,566,316 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036157838   ⟹   XP_036013731
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391394,494,853 - 94,702,824 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036157839   ⟹   XP_036013732
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391394,494,853 - 94,702,824 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001780749
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391394,494,853 - 94,702,824 (+)NCBI
GRCm381394,358,966 - 94,566,316 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004937934
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391394,494,853 - 94,702,824 (+)NCBI
Sequence:
RefSeq Acc Id: XR_382728
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391394,494,853 - 94,702,824 (+)NCBI
GRCm381394,358,966 - 94,566,316 (+)NCBI
Sequence:
RefSeq Acc Id: NP_033810   ⟸   NM_009680
- UniProtKB: E9QQ08 (UniProtKB/Swiss-Prot),   Q91YR4 (UniProtKB/Swiss-Prot),   Q9Z1T1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006517586   ⟸   XM_006517523
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000155984   ⟸   ENSMUST00000231916
Ensembl Acc Id: ENSMUSP00000022196   ⟸   ENSMUST00000022196
RefSeq Acc Id: XP_036013731   ⟸   XM_036157838
- Peptide Label: isoform X2
RefSeq Acc Id: XP_036013732   ⟸   XM_036157839
- Peptide Label: isoform X3
Protein Domains
AP-3 complex subunit beta 1 serine-rich   AP-3 complex subunit beta C-terminal   Beta-adaptin appendage C-terminal subdomain   Clathrin/coatomer adaptor adaptin-like N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z1T1-F1-model_v2 AlphaFold Q9Z1T1 1-1105 view protein structure

Promoters
RGD ID:8681032
Promoter ID:EPDNEW_M18547
Type:initiation region
Name:Ap3b1_1
Description:Mus musculus adaptor-related protein complex 3, beta 1 subunit, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381394,359,007 - 94,359,067EPDNEW
RGD ID:6823702
Promoter ID:MM_KWN:14939
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:AK141947_GM9776,   NM_009680
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361395,128,456 - 95,129,072 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1333879 AgrOrtholog
Ensembl Genes ENSMUSG00000021686 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000022196 ENTREZGENE
  ENSMUST00000022196.5 UniProtKB/Swiss-Prot
  ENSMUST00000231916.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AP3_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AP3B1_Ser UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AP3B_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AP_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AP_complex_bsu_1_2_4 UniProtKB/TrEMBL
  ARM-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  B-adaptin_app_sub_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Clathrin/coatomer_adapt-like_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11774 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1333879 ENTREZGENE
NCBI Gene 11774 ENTREZGENE
PANTHER AP-3 COMPLEX SUBUNIT BETA-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11134 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Adaptin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AP3B1_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEEEED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ap3b1 PhenoGen
PIRSF AP3_complex_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AP_complex_beta UniProtKB/TrEMBL
SMART AP3B1_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  B2-adapt-app_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A338P6V5_MOUSE UniProtKB/TrEMBL
  AP3B1_MOUSE UniProtKB/Swiss-Prot
  E9QQ08 ENTREZGENE
  Q3TQ07_MOUSE UniProtKB/TrEMBL
  Q3TQ33_MOUSE UniProtKB/TrEMBL
  Q3UPG0_MOUSE UniProtKB/TrEMBL
  Q91YR4 ENTREZGENE
  Q9Z1T1 ENTREZGENE
UniProt Secondary E9QQ08 UniProtKB/Swiss-Prot
  Q91YR4 UniProtKB/Swiss-Prot