Abcb1a (ATP-binding cassette, sub-family B (MDR/TAP), member 1A) - Rat Genome Database

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Gene: Abcb1a (ATP-binding cassette, sub-family B (MDR/TAP), member 1A) Mus musculus
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Symbol: Abcb1a
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 1A
RGD ID: 1620890
MGI Page MGI
Description: Enables several functions, including ATP hydrolysis activity; ATPase-coupled intramembrane lipid transporter activity; and efflux transmembrane transporter activity. Involved in export across plasma membrane; lipid transport; and xenobiotic transport across blood-brain barrier. Acts upstream of or within xenobiotic detoxification by transmembrane export across the plasma membrane. Located in apical plasma membrane and intercellular canaliculus. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and integumental system. Used to study inflammatory bowel disease 13. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); human immunodeficiency virus infectious disease (multiple); inflammatory bowel disease (multiple); and leukemia (multiple). Orthologous to human ABCB1 (ATP binding cassette subfamily B member 1).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Abcb4; ATP-binding cassette sub-family B member 1A; ATP-binding cassette, sub-family B (MDR/TAP), member 4; ATP-binding cassette, subfamily B, member 1A; ATP-dependent translocase ABCB1; ecotropic viral integration site 32; Evi; Evi32; Mdr; mdr-; mdr-3; Mdr1a; Mdr3; multi-drug resistance 3; multidrug resistance protein 1A; multidrug resistance protein 3; multiple drug resistant 1a; P; P glycoprotein 3; P-; P-glycoprotein 3; P-gp; Pgp; Pgy; Pgy-; Pgy-3; Pgy3; phospholipid transporter ABCB1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
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Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3958,617,091 - 8,798,575 (+)NCBIGRCm39mm39
GRCm39 Ensembl58,710,077 - 8,798,575 (+)Ensembl
GRCm3858,567,091 - 8,748,575 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl58,660,077 - 8,748,575 (+)EnsemblGRCm38mm10GRCm38
MGSCv3758,660,092 - 8,748,570 (+)NCBIGRCm37mm9NCBIm37
MGSCv3658,666,098 - 8,754,525 (+)NCBImm8
Celera58,580,580 - 8,668,151 (+)NCBICelera
Cytogenetic Map5A1NCBI
cM Map53.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model