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Gene: Abcb1a (ATP-binding cassette, sub-family B (MDR/TAP), member 1A) Mus musculus
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Symbol: Abcb1a
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 1A
Description: Exhibits ATPase activity, coupled; ATPase-coupled intramembrane lipid transporter activity; and transmembrane transporter activity. Involved in lipid translocation; xenobiotic detoxification by transmembrane export across the plasma membrane; and xenobiotic transport across blood-brain barrier. Localizes to the apical plasma membrane and intercellular canaliculus. Used to study inflammatory bowel disease 13. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; allergic rhinitis; carcinoma (multiple); inflammatory bowel disease (multiple); and leukemia (multiple). Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and integumental system. Orthologous to human ABCB1 (ATP binding cassette subfamily B member 1).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Abcb4; ATP-binding cassette sub-family B member 1A; ATP-binding cassette, sub-family B (MDR/TAP), member 4; ATP-binding cassette, subfamily B, member 1A; ATP-dependent translocase ABCB1; ecotropic viral integration site 32; Evi32; mdr-3; Mdr1a; Mdr3; multi-drug resistance 3; multidrug resistance protein 1A; multidrug resistance protein 3; multiple drug resistant 1a; P glycoprotein 3; P-glycoprotein 3; P-gp; Pgp; Pgy-3; Pgy3; phospholipid transporter ABCB1
Orthologs:
Homo sapiens (human) : ABCB1 (ATP binding cassette subfamily B member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Abcb1a (ATP binding cassette subfamily B member 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abcb1 (ATP binding cassette subfamily B member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCB1 (ATP binding cassette subfamily B member 1)
Canis lupus familiaris (dog) : ABCB1 (ATP binding cassette subfamily B member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcb1 (ATP binding cassette subfamily B member 1)
Sus scrofa (pig) : ABCB1 (ATP-binding cassette, sub-family B (MDR/TAP), member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3858,567,091 - 8,748,575 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3758,660,092 - 8,748,570 (+)NCBIGRCm37mm9NCBIm37
MGSCv3658,666,098 - 8,754,525 (+)NCBImm8
Celera58,580,580 - 8,668,151 (+)NCBICelera
Cytogenetic Map5 A1NCBI
cM Map53.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations