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Gene: Mafb (v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)) Mus musculus
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Symbol: Mafb
Name: v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including abducens nerve formation; animal organ development; and negative regulation of osteoclast differentiation. Localizes to nucleus and transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Used to study Duane retraction syndrome and multicentric carpotarsal osteolysis syndrome. Human ortholog(s) of this gene implicated in Duane retraction syndrome and multicentric carpotarsal osteolysis syndrome. Orthologous to human MAFB (MAF bZIP transcription factor B); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,2-dichloroethane; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: kr; Kreisler; Kreisler (maf-related) leucine zipper protein; Krml; Krml1; maf-B; segmentation protein Kr; transcription factor Maf-1; transcription factor MafB; V-maf musculoaponeurotic fibrosarcoma oncogene homolog B
Orthologs:
Homo sapiens (human) : MAFB (MAF bZIP transcription factor B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mafb (MAF bZIP transcription factor B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mafb (MAF bZIP transcription factor B)
Pan paniscus (bonobo/pygmy chimpanzee) : MAFB (MAF bZIP transcription factor B)
Canis lupus familiaris (dog) : MAFB (MAF bZIP transcription factor B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mafb (MAF bZIP transcription factor B)
Sus scrofa (pig) : MAFB (MAF bZIP transcription factor B)
Chlorocebus sabaeus (African green monkey) : MAFB (MAF bZIP transcription factor B)
Heterocephalus glaber (naked mole-rat) : Mafb (MAF bZIP transcription factor B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl2160,363,703 - 160,367,065 (-)EnsemblGRCm38mm10GRCm38
GRCm382160,363,677 - 160,367,065 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372160,189,413 - 160,192,801 (-)NCBIGRCm37mm9NCBIm37
MGSCv362160,055,202 - 160,058,455 (-)NCBImm8
Celera2166,294,850 - 166,298,242 (-)NCBICelera
Cytogenetic Map2H2NCBI
cM Map280.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on Mafb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732546
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.