Srebf2 (sterol regulatory element binding factor 2) - Rat Genome Database

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Gene: Srebf2 (sterol regulatory element binding factor 2) Mus musculus
Analyze
Symbol: Srebf2
Name: sterol regulatory element binding factor 2
RGD ID: 730973
MGI Page MGI
Description: Enables DNA-binding transcription factor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in positive regulation of cholesterol biosynthetic process; positive regulation of miRNA transcription; and positive regulation of myelination. Acts upstream of or within cholesterol homeostasis and positive regulation of transcription by RNA polymerase II. Located in cytoplasm; membrane; and nucleus. Is expressed in several structures, including 1st branchial arch; genitourinary system; limb; nervous system; and retina. Human ortholog(s) of this gene implicated in carotid artery disease; diabetes mellitus (multiple); prostate cancer; sarcoma; and vascular dementia. Orthologous to human SREBF2 (sterol regulatory element binding transcription factor 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI608257; bHLHd; bHLHd2; lo; lop13; nu; nuc; SRE; SREB; SREBP; SREBP-2; SREBP2; SREBP2gc; sterol regulatory element-binding protein 2; sterol regulatory element-binding transcription factor 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391582,031,455 - 82,089,580 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1582,031,382 - 82,089,580 (+)EnsemblGRCm39 Ensembl
GRCm381582,147,269 - 82,205,379 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1582,147,181 - 82,205,379 (+)EnsemblGRCm38mm10GRCm38
MGSCv371581,977,699 - 82,035,390 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361581,974,524 - 82,032,215 (+)NCBIMGSCv36mm8
Celera1584,270,919 - 84,328,680 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1538.49NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-isolariciresinol  (ISO)
(-)-epigallocatechin 3-gallate  (EXP)
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
1,3-dichloropropan-2-ol  (EXP,ISO)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,6-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
25-hydroxycholesterol  (ISO)
5-fluorouracil  (ISO)
acetamide  (ISO)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
allethrin  (ISO)
alliin  (ISO)
allopurinol  (ISO)
alpha-pinene  (ISO)
amitriptyline  (ISO)
amphotericin B  (EXP)
ampicillin  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
aristolochic acid A  (ISO)
aspartame  (EXP)
atorvastatin calcium  (ISO)
atrazine  (ISO)
benzalkonium chloride  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-cyclodextrin  (ISO)
bezafibrate  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP,ISO)
CGP 52608  (ISO)
CGS-21680  (ISO)
chlorpromazine  (ISO)
chlorpyrifos  (EXP)
cholesterol  (ISO)
choline  (EXP)
chromium(6+)  (EXP)
cisplatin  (ISO)
citalopram  (ISO)
clofibrate  (ISO)
clomipramine  (ISO)
clozapine  (ISO)
cobalt dichloride  (ISO)
colforsin daropate hydrochloride  (ISO)
copper(II) chloride  (ISO)
crizotinib  (ISO)
CU-O LINKAGE  (ISO)
curcumin  (EXP,ISO)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
cypermethrin  (ISO)
D-glucose  (ISO)
DDT  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (EXP)
dicrotophos  (ISO)
dimethylarsinic acid  (EXP)
dinophysistoxin 1  (ISO)
dorsomorphin  (EXP,ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP)
ezetimibe  (ISO)
fenarimol  (ISO)
fenvalerate  (ISO)
fisetin  (ISO)
Ganoderic acid A  (EXP,ISO)
geraniol  (ISO)
glafenine  (ISO)
glucose  (ISO)
glyphosate  (EXP)
haloperidol  (ISO)
herbacetin  (EXP)
hydrogen peroxide  (EXP,ISO)
imipramine  (ISO)
ketoconazole  (ISO)
L-ascorbic acid  (EXP,ISO)
L-methionine  (EXP)
lead diacetate  (ISO)
lead nitrate  (ISO)
lead(0)  (EXP)
linalool  (EXP,ISO)
lipopolysaccharide  (ISO)
lovastatin  (EXP,ISO)
mercury dichloride  (ISO)
metformin  (EXP,ISO)
methylarsonic acid  (EXP)
metronidazole  (EXP)
mevalonic acid  (ISO)
mevastatin  (EXP,ISO)
microcystin-LR  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
Monobutylphthalate  (EXP)
monocrotophos  (ISO)
monosodium L-glutamate  (EXP)
Morroniside  (EXP)
myricetin  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
neomycin  (EXP)
obeticholic acid  (EXP,ISO)
okadaic acid  (ISO)
olanzapine  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
phenylpropanolamine  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
pyrethrins  (ISO)
quercetin  (ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
simvastatin  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP)
Soman  (ISO)
streptozocin  (EXP,ISO)
sulindac sulfide  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
testosterone  (EXP)
thioacetamide  (ISO)
tributyl phosphate  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tungsten  (EXP)
tunicamycin  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (EXP)
vinclozolin  (ISO)
vorinostat  (ISO)
withaferin A  (EXP)
xanthohumol  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Obesity-related overexpression of fatty-acid synthase gene in adipose tissue involves sterol regulatory element-binding protein transcription factors. Boizard M, etal., J Biol Chem. 1998 Oct 30;273(44):29164-71.
2. Increased gene expression of liver SREBP-2 in experimental chronic renal failure. Chmielewski M, etal., Atherosclerosis. 2007 Apr;191(2):326-32. Epub 2006 Jun 30.
3. Protective effect of Chinese prescription Kangen-karyu and its crude drug Tanjin against age-related lipidosis in rats. Cho EJ, etal., J Pharm Pharmacol. 2007 May;59(5):687-94.
4. Xanthohumol ameliorates atherosclerotic plaque formation, hypercholesterolemia, and hepatic steatosis in ApoE-deficient mice. Doddapattar P, etal., Mol Nutr Food Res. 2013 Oct;57(10):1718-28. doi: 10.1002/mnfr.201200794. Epub 2013 May 3.
5. The effect of sterol regulatory element-binding protein 2 polymorphism on the serum lipid in northern Chinese subjects. Duan X, etal., J Lipid Res. 2005 Feb;46(2):252-7. Epub 2004 Nov 16.
6. Dysregulation of sterol response element-binding proteins and downstream effectors in prostate cancer during progression to androgen independence. Ettinger SL, etal., Cancer Res. 2004 Mar 15;64(6):2212-21.
7. Mutant p53: one name, many proteins. Freed-Pastor WA and Prives C, Genes Dev. 2012 Jun 15;26(12):1268-86. doi: 10.1101/gad.190678.112.
8. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
9. Cholesterol accumulation and diabetes in pancreatic beta-cell-specific SREBP-2 transgenic mice: a new model for lipotoxicity. Ishikawa M, etal., J Lipid Res. 2008 Dec;49(12):2524-34. Epub 2008 Aug 5.
10. Calorie restriction modulates renal expression of sterol regulatory element binding proteins, lipid accumulation, and age-related renal disease. Jiang T, etal., J Am Soc Nephrol. 2005 Aug;16(8):2385-94. Epub 2005 Jun 8.
11. Role of altered renal lipid metabolism and the sterol regulatory element binding proteins in the pathogenesis of age-related renal disease. Jiang T, etal., Kidney Int. 2005 Dec;68(6):2608-20.
12. Sterol Regulatory Element-Binding Proteins, Liver X Receptor, ABCA1 Transporter, CD36, Scavenger Receptors A1 and B1 in Nephrotic Kidney. Kim HJ and Vaziri ND, Am J Nephrol. 2009 Jan 16;29(6):607-614.
13. Localization of the transcription factor, sterol regulatory element binding protein-2 (SREBP-2) in the normal rat brain and changes after kainate-induced excitotoxic injury. Kim JH and Ong WY, J Chem Neuroanat. 2009 Mar;37(2):71-7. Epub 2008 Dec 13.
14. Analysis of the SREBF2 gene as a genetic risk factor for vascular dementia. Kim Y, etal., Am J Med Genet B Neuropsychiatr Genet. 2005 Nov 5;139(1):19-22.
15. Suppression of hepatic cholesteryl ester transfer protein expression in obese humans with the development of type 2 diabetes mellitus. MacLean PS, etal., J Clin Endocrinol Metab. 2005 Apr;90(4):2250-8. Epub 2005 Jan 11.
16. Impact of maternal circulating cholesterol and gestational diabetes mellitus on lipid metabolism in human term placenta. Marseille-Tremblay C, etal., Mol Reprod Dev. 2008 Jun;75(6):1054-62.
17. MGDs mouse GO annotations MGD data from the GO Consortium
18. p53 mutations in cancer. Muller PA and Vousden KH, Nat Cell Biol. 2013 Jan;15(1):2-8. doi: 10.1038/ncb2641.
19. Identification of mutations in the gene encoding sterol regulatory element binding protein (SREBP)-2 in hypercholesterolaemic subjects. Muller PY and Miserez AR, J Med Genet. 2002 Apr;39(4):271-5.
20. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
21. Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been. Osborne TF and Espenshade PJ, Genes Dev. 2009 Nov 15;23(22):2578-91.
22. Modified HMG-CoA reductase and LDLr regulation is deeply involved in age-related hypercholesterolemia. Pallottini V, etal., J Cell Biochem. 2006 Aug 1;98(5):1044-53.
23. Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes. Proctor G, etal., Diabetes. 2006 Sep;55(9):2502-9.
24. Expression of Sterol Regulatory Element-Binding Proteins in epicardial adipose tissue in patients with coronary artery disease and diabetes mellitus: preliminary study. Pérez-Belmonte LM, etal., Int J Med Sci. 2017 Feb 23;14(3):268-274. doi: 10.7150/ijms.17821. eCollection 2017.
25. Mouse MP Annotation Import Pipeline RGD automated import pipeline
26. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
27. Characterization of polymorphic structure of SREBP-2 gene: role in atherosclerosis. Robinet P, etal., Atherosclerosis. 2003 Jun;168(2):381-7.
28. A phase II study of ENMD-2076 in advanced soft tissue sarcoma (STS). Veitch Z, etal., Sci Rep. 2019 May 14;9(1):7390. doi: 10.1038/s41598-019-43222-6.
29. Expression of a novel, sterol-insensitive form of sterol regulatory element binding protein 2 (SREBP2) in male germ cells suggests important cell- and stage-specific functions for SREBP targets during spermatogenesis. Wang H, etal., Mol Cell Biol 2002 Dec;22(24):8478-90.
30. Regulation of renal lipid metabolism, lipid accumulation, and glomerulosclerosis in FVBdb/db mice with type 2 diabetes. Wang Z, etal., Diabetes. 2005 Aug;54(8):2328-35.
31. Cyclosporin-induced dyslipoproteinemia is associated with selective activation of SREBP-2. Wu J, etal., Am J Physiol. 1999 Dec;277(6 Pt 1):E1087-94.
32. Impaired regulation of sterol regulatory element binding protein 2 in cholesterol gallstone-susceptible mice. Xu G, etal., Biochim Biophys Acta. 2004 Apr 5;1688(3):274-9.
Additional References at PubMed
PMID:7803821   PMID:8343131   PMID:8827514   PMID:8833906   PMID:8889548   PMID:9196007   PMID:9329978   PMID:9756919   PMID:9789033   PMID:9974430   PMID:10349636   PMID:10397761  
PMID:10512203   PMID:10585467   PMID:11042159   PMID:11076861   PMID:11090130   PMID:11208732   PMID:11217851   PMID:11544199   PMID:11739104   PMID:11812828   PMID:11829742   PMID:11929849  
PMID:12032166   PMID:12160734   PMID:12242332   PMID:12477932   PMID:12520002   PMID:12668174   PMID:12829694   PMID:12855700   PMID:12904583   PMID:12943732   PMID:14512514   PMID:14522948  
PMID:14610273   PMID:14662765   PMID:14673138   PMID:14722362   PMID:15102471   PMID:15226823   PMID:15572673   PMID:15589694   PMID:15782199   PMID:15840001   PMID:16046411   PMID:16100574  
PMID:16141072   PMID:16141073   PMID:16332269   PMID:16455790   PMID:16879892   PMID:16890542   PMID:17300749   PMID:17890326   PMID:17916878   PMID:17921436   PMID:17967808   PMID:18287559  
PMID:18413311   PMID:18557763   PMID:18799693   PMID:18846256   PMID:19110480   PMID:19244508   PMID:19500568   PMID:19748890   PMID:19808779   PMID:19915177   PMID:20059953   PMID:20138838  
PMID:20211142   PMID:20466882   PMID:20510003   PMID:20566875   PMID:20732877   PMID:20926756   PMID:21084441   PMID:21109190   PMID:21459322   PMID:21816276   PMID:21858719   PMID:21873635  
PMID:21944868   PMID:22005015   PMID:22361881   PMID:22441164   PMID:22573382   PMID:22666465   PMID:22675522   PMID:22985732   PMID:22988430   PMID:23000402   PMID:23000407   PMID:23536474  
PMID:23542164   PMID:23563690   PMID:23823476   PMID:23838163   PMID:23881913   PMID:24068000   PMID:24360166   PMID:24465397   PMID:24516236   PMID:24675665   PMID:24952961   PMID:25218172  
PMID:25550450   PMID:25593129   PMID:25646300   PMID:25777360   PMID:25794851   PMID:26028026   PMID:26184741   PMID:26199412   PMID:26508642   PMID:26634251   PMID:26685326   PMID:26984409  
PMID:27008858   PMID:27137100   PMID:27416896   PMID:27601673   PMID:27752896   PMID:27767079   PMID:28244871   PMID:28378742   PMID:28549068   PMID:28630260   PMID:28676202   PMID:29472293  
PMID:29899135   PMID:30074985   PMID:30195495   PMID:30604742   PMID:30821074   PMID:31303399   PMID:31875875   PMID:32098917   PMID:32266253   PMID:32325033   PMID:32554809   PMID:33591268  
PMID:33878353   PMID:33942715   PMID:34021134   PMID:34644558   PMID:35120997   PMID:36519761   PMID:36534812   PMID:36653891   PMID:37647408   PMID:37949368   PMID:38092754  


Genomics

Comparative Map Data
Srebf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391582,031,455 - 82,089,580 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1582,031,382 - 82,089,580 (+)EnsemblGRCm39 Ensembl
GRCm381582,147,269 - 82,205,379 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1582,147,181 - 82,205,379 (+)EnsemblGRCm38mm10GRCm38
MGSCv371581,977,699 - 82,035,390 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361581,974,524 - 82,032,215 (+)NCBIMGSCv36mm8
Celera1584,270,919 - 84,328,680 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1538.49NCBI
SREBF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382241,833,105 - 41,907,305 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2241,833,105 - 41,907,306 (+)EnsemblGRCh38hg38GRCh38
GRCh372242,229,109 - 42,303,309 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,559,052 - 40,632,321 (+)NCBINCBI36Build 36hg18NCBI36
Build 342240,553,605 - 40,626,873NCBI
Celera2226,035,175 - 26,108,609 (+)NCBICelera
Cytogenetic Map22q13.2NCBI
HuRef2225,194,635 - 25,269,011 (+)NCBIHuRef
CHM1_12242,189,135 - 42,263,520 (+)NCBICHM1_1
T2T-CHM13v2.02242,311,716 - 42,386,086 (+)NCBIT2T-CHM13v2.0
Srebf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87115,542,774 - 115,600,945 (+)NCBIGRCr8
mRatBN7.27113,663,202 - 113,720,850 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7113,663,202 - 113,720,848 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7115,419,363 - 115,476,823 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07117,642,866 - 117,700,330 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07117,612,307 - 117,669,771 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07123,381,082 - 123,438,605 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7123,381,077 - 123,438,603 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07123,364,495 - 123,422,296 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,522,511 - 120,580,212 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17120,556,723 - 120,612,972 (+)NCBI
Celera7109,978,519 - 110,036,018 (+)NCBICelera
Cytogenetic Map7q34NCBI
Srebf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541327,271,953 - 27,326,759 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541327,271,717 - 27,326,655 (+)NCBIChiLan1.0ChiLan1.0
SREBF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22351,657,608 - 51,736,920 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12254,357,504 - 54,436,161 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02222,725,790 - 22,799,749 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12240,811,459 - 40,884,947 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2240,811,459 - 40,884,947 (+)Ensemblpanpan1.1panPan2
Srebf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049457,105,519 - 7,164,174 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936492115,821 - 174,775 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936492115,923 - 174,614 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SREBF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl56,719,490 - 6,784,671 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.156,719,484 - 6,784,724 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SREBF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11924,364,725 - 24,439,851 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1924,364,911 - 24,440,014 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045100,972,400 - 101,047,348 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Srebf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247526,816,468 - 6,871,567 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247526,815,075 - 6,871,674 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Srebf2
2135 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:770
Count of miRNA genes:445
Interacting mature miRNAs:513
Transcripts:ENSMUST00000023100
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
1301429Pcir3_mperiosteal circumference 3 (mouse)Not determined154846536282465496Mouse
4142198Hbtq_mhabituation QTL (mouse)Not determined155116070885160833Mouse
10045637Heal27_mwound healing/regeneration 29 (mouse)Not determined155141836185418511Mouse
10412067Pain2_mpain 2 (mouse)Not determined155164533985645626Mouse
1302080Szs13_mseizure susceptibility 13 (mouse)Not determined155168583285694449Mouse
1301708Cocrb14_mcocaine related behavior 14 (mouse)Not determined155180651585806651Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155478912988789129Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
27095936Ulnl4_mulna length 4, 5 week (mouse)155676339687684201Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
15092079Igly6_mIgG glycosylation 6, GP6 (mouse)157410054082674156Mouse
1301472Pain1_mpain 1 (mouse)Not determined157532084690813185Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
15092080Igly7_mIgG glycosylation 7, GP10 (mouse)157779491982674156Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1578897881104073951Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579163411104073951Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined79908940104073951Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580313634104073951Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580884933104073951Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580884933104073951Mouse

Markers in Region
AI608257  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381582,205,137 - 82,205,231UniSTSGRCm38
MGSCv371582,035,567 - 82,035,661UniSTSGRCm37
Celera1584,328,857 - 84,328,951UniSTS
Cytogenetic Map15E1UniSTS
Whitehead/MRC_RH15724.09UniSTS
D9Mit34.1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map2C1.3UniSTS
Cytogenetic Map19D1UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11B4UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map1C1.3UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map2E2UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map1E3UniSTS
Cytogenetic Map5E1UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map16B3UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map19D3UniSTS
Cytogenetic Map1H5UniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map9DUniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map17DUniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map13A1UniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map12A3UniSTS
Cytogenetic Map1H2.1UniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map6A2UniSTS
Cytogenetic Map7B1UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map5C3.1UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map11B1.1UniSTS
Cytogenetic Map1H6UniSTS
Cytogenetic Map2C2UniSTS
Cytogenetic Map19CUniSTS
Cytogenetic Map17E1.3UniSTS
Cytogenetic Map5A1UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map13A5UniSTS
Cytogenetic MapXA1.1UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map3A3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map8CUniSTS
Cytogenetic Map12EUniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map1H1UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map1A2UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXC-DUniSTS
Cytogenetic Map5G1.3UniSTS
Cytogenetic Map7D1-E2UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map1H2.2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map16C1.1UniSTS
Cytogenetic Map15F2UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map1H4-H6UniSTS
Cytogenetic Map12D2UniSTS
Cytogenetic Map1G3UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map1H3UniSTS
Cytogenetic Map19BUniSTS
cM Map950.0UniSTS
Whitehead Genetic943.7UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001411792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_033218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC102176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC105358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF289715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF374267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC014730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC023333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC048071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG800576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ963055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ965109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB228109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000023100   ⟹   ENSMUSP00000023100
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1582,031,382 - 82,089,580 (+)Ensembl
GRCm38.p6 Ensembl1582,147,181 - 82,205,379 (+)Ensembl
RefSeq Acc Id: ENSMUST00000229009   ⟹   ENSMUSP00000154839
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1582,032,214 - 82,055,468 (+)Ensembl
GRCm38.p6 Ensembl1582,148,013 - 82,171,267 (+)Ensembl
RefSeq Acc Id: ENSMUST00000229336   ⟹   ENSMUSP00000155022
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1582,031,405 - 82,088,876 (+)Ensembl
GRCm38.p6 Ensembl1582,147,204 - 82,204,675 (+)Ensembl
RefSeq Acc Id: ENSMUST00000229518
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1582,032,226 - 82,054,362 (+)Ensembl
GRCm38.p6 Ensembl1582,148,025 - 82,170,161 (+)Ensembl
RefSeq Acc Id: ENSMUST00000230105
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1582,031,452 - 82,058,095 (+)Ensembl
GRCm38.p6 Ensembl1582,147,251 - 82,173,894 (+)Ensembl
RefSeq Acc Id: ENSMUST00000230955   ⟹   ENSMUSP00000155331
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1582,079,173 - 82,088,020 (+)Ensembl
GRCm38.p6 Ensembl1582,194,972 - 82,203,819 (+)Ensembl
RefSeq Acc Id: ENSMUST00000231065
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1582,031,447 - 82,057,826 (+)Ensembl
GRCm38.p6 Ensembl1582,147,246 - 82,173,625 (+)Ensembl
RefSeq Acc Id: NM_001411792   ⟹   NP_001398721
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391582,031,842 - 82,089,580 (+)NCBI
RefSeq Acc Id: NM_033218   ⟹   NP_150087
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391582,031,455 - 82,089,580 (+)NCBI
GRCm381582,147,269 - 82,204,960 (+)NCBI
MGSCv371581,977,699 - 82,035,390 (+)RGD
Celera1584,270,919 - 84,328,680 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_150087   ⟸   NM_033218
- Peptide Label: isoform 1
- UniProtKB: Q925C2 (UniProtKB/Swiss-Prot),   Q9ESZ4 (UniProtKB/Swiss-Prot),   Q3U1N2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000155331   ⟸   ENSMUST00000230955
RefSeq Acc Id: ENSMUSP00000023100   ⟸   ENSMUST00000023100
RefSeq Acc Id: ENSMUSP00000155022   ⟸   ENSMUST00000229336
RefSeq Acc Id: ENSMUSP00000154839   ⟸   ENSMUST00000229009
RefSeq Acc Id: NP_001398721   ⟸   NM_001411792
- Peptide Label: isoform 2
Protein Domains
bHLH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3U1N2-F1-model_v2 AlphaFold Q3U1N2 1-1130 view protein structure

Promoters
RGD ID:6826515
Promoter ID:MM_KWN:19191
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000023100,   ENSMUST00000100393,   UC007WYH.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361581,976,736 - 81,977,777 (+)MPROMDB
RGD ID:6847266
Promoter ID:MM_ACW:18840
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   Spleen
Transcripts:SREBF2.HSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361582,033,959 - 82,034,459 (+)MPROMDB
RGD ID:8684486
Promoter ID:EPDNEW_M20274
Type:multiple initiation site
Name:Srebf2_1
Description:Mus musculus sterol regulatory element binding factor 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M20275  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381582,147,261 - 82,147,321EPDNEW
RGD ID:8684488
Promoter ID:EPDNEW_M20275
Type:initiation region
Name:Srebf2_2
Description:Mus musculus sterol regulatory element binding factor 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M20274  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381582,147,383 - 82,147,443EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107585 AgrOrtholog
Ensembl Genes ENSMUSG00000022463 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000023100 ENTREZGENE
  ENSMUST00000023100.8 UniProtKB/Swiss-Prot
  ENSMUST00000229009.2 UniProtKB/TrEMBL
  ENSMUST00000229336.2 UniProtKB/Swiss-Prot
  ENSMUST00000230955.2 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot
InterPro bHLH_dom UniProtKB/Swiss-Prot
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot
  Ig/MHC_CS UniProtKB/Swiss-Prot
KEGG Report mmu:20788 UniProtKB/Swiss-Prot
MGD MGI:107585 ENTREZGENE
NCBI Gene 20788 ENTREZGENE
PANTHER STEROL REGULATORY ELEMENT-BINDING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STEROL REGULATORY ELEMENT-BINDING PROTEIN 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HLH UniProtKB/Swiss-Prot
PhenoGen Srebf2 PhenoGen
PROSITE BHLH UniProtKB/Swiss-Prot
SMART HLH UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot
UniProt A0A2R8VH82_MOUSE UniProtKB/TrEMBL
  A0A2R8VHQ9_MOUSE UniProtKB/TrEMBL
  Q3U1N2 ENTREZGENE
  Q8BPL7_MOUSE UniProtKB/TrEMBL
  Q925C2 ENTREZGENE
  Q9ESZ4 ENTREZGENE
  SRBP2_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q925C2 UniProtKB/Swiss-Prot
  Q9ESZ4 UniProtKB/Swiss-Prot