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Gene: Vldlr (very low density lipoprotein receptor) Mus musculus
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Symbol: Vldlr
Name: very low density lipoprotein receptor
Description: Exhibits reelin receptor activity. Involved in nervous system development; positive regulation of protein kinase activity; and reelin-mediated signaling pathway. Localizes to extracellular space. Is expressed in several structures, including alimentary system; genitourinary system; musculoskeletal system; nervous system; and sensory organ. Used to study age related macular degeneration 1. Human ortholog(s) of this gene implicated in Alzheimer's disease; cerebellar ataxia, mental retardation and dysequlibrium syndrome; and dementia. Orthologous to human VLDLR (very low density lipoprotein receptor); PARTICIPATES IN Reelin signaling pathway; altered Reelin signaling pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA408956; AI451093; AW047288; very low-density lipoprotein receptor; VLDL receptor; VLDL-R
Orthologs:
Homo sapiens (human) : VLDLR (very low density lipoprotein receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Vldlr (very low density lipoprotein receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vldlr (very low density lipoprotein receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : VLDLR (very low density lipoprotein receptor)
Canis lupus familiaris (dog) : VLDLR (very low density lipoprotein receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vldlr (very low density lipoprotein receptor)
Sus scrofa (pig) : VLDLR (very low density lipoprotein receptor)
Chlorocebus sabaeus (African green monkey) : VLDLR (very low density lipoprotein receptor)
Heterocephalus glaber (naked mole-rat) : Vldlr (very low density lipoprotein receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1927,216,484 - 27,254,231 (+)EnsemblGRCm38mm10GRCm38
GRCm381927,216,480 - 27,254,231 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371927,291,510 - 27,328,721 (+)NCBIGRCm37mm9NCBIm37
MGSCv361927,284,529 - 27,316,717 (+)NCBImm8
Celera1928,001,119 - 28,038,314 (+)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1921.77NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on Vldlr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733927
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-07-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.