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Gene: Rhoa (ras homolog family member A) Mus musculus
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Symbol: Rhoa
Name: ras homolog family member A
Description: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: aplysia ras-related homolog A; aplysia ras-related homolog A1; aplysia ras-related homolog A2; Arha; Arha1; Arha2; Ras family member A; ras homolog A1; ras homolog A2; ras homolog gene family, member A; ras homolog gene family, member A1; ras homolog gene family, member A2; Rho family GTPase; transforming protein RhoA
Orthologs:
Homo sapiens (human) : RHOA (ras homolog family member A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rhoa (ras homolog family member A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rhoa (ras homolog family member A)
Pan paniscus (bonobo/pygmy chimpanzee) : RHOA (ras homolog family member A)
Canis lupus familiaris (dog) : RHOA (ras homolog family member A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rhoa (ras homolog family member A)
Sus scrofa (pig) : RHOA (ras homolog family member A)
more info ...
Related Pseudogenes: Gm12844   Gm2325   Gm6137   Rhoay-ps1   Rhoay-ps2   Rhoay-ps3  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389108,306,160 - 108,337,943 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379108,208,536 - 108,240,270 (+)NCBIGRCm37mm9NCBIm37
MGSCv369108,164,298 - 108,196,026 (+)NCBImm8
Celera9107,915,249 - 107,947,041 (+)NCBICelera
Cytogenetic Map9 F1-F2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Rhoa
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731060
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.