Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MRPL22 mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of MRPL22 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MRPL22 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of MRPL22 mRNA | CTD | PMID:25975270 | 2,4-dinitrotoluene | affects expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of MRPL22 mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | decreases expression | ISO | MRPL22 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of MRPL22 mRNA | CTD | PMID:30851411 | 2-methylcholine | affects expression | ISO | MRPL22 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of MRPL22 mRNA | CTD | PMID:21179406 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | MRPL22 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of MRPL22 mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of MRPL22 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | affects expression | ISO | MRPL22 (Homo sapiens) | 6480464 | bisphenol S affects the expression of MRPL22 protein | CTD | PMID:31945527 | 6-propyl-2-thiouracil | increases expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of MRPL22 mRNA | CTD | PMID:30047161 | aconitine | decreases expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | Aconitine results in decreased expression of MRPL22 protein | CTD | PMID:33236894 | amitrole | increases expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of MRPL22 mRNA | CTD | PMID:30047161 | antirheumatic drug | multiple interactions | ISO | MRPL22 (Homo sapiens) | 6480464 | [Antirheumatic Agents co-treated with Methotrexate] results in decreased expression of MRPL22 mRNA | CTD | PMID:16817978 | arsenite(3-) | multiple interactions | ISO | MRPL22 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to MRPL22 mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of MRPL22 mRNA | CTD | PMID:22228805 | bisphenol A | increases expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of MRPL22 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MRPL22 mRNA | CTD | PMID:33221593 | Bisphenol B | increases expression | ISO | MRPL22 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of MRPL22 protein | CTD | PMID:34186270 | bisphenol F | multiple interactions | ISO | MRPL22 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of MRPL22 mRNA | CTD | PMID:28628672 | bisphenol F | increases expression | ISO | MRPL22 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of MRPL22 protein | CTD | PMID:34186270 | cadmium dichloride | decreases expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased expression of MRPL22 mRNA | CTD | PMID:33453195 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | MRPL22 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to MRPL22 gene] | CTD | PMID:28238834 | cylindrospermopsin | increases expression | ISO | MRPL22 (Homo sapiens) | 6480464 | cylindrospermopsin results in increased expression of MRPL22 mRNA | CTD | PMID:24921660 | dexamethasone | multiple interactions | ISO | MRPL22 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of MRPL22 mRNA | CTD | PMID:28628672 | dicrotophos | decreases expression | ISO | MRPL22 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of MRPL22 mRNA | CTD | PMID:28302478 | epoxiconazole | increases expression | EXP | | 6480464 | epoxiconazole results in increased expression of MRPL22 mRNA | CTD | PMID:35436446 | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of MRPL22 mRNA | CTD | PMID:30319688 | fenthion | increases expression | EXP | | 6480464 | Fenthion results in increased expression of MRPL22 mRNA | CTD | PMID:34813904 | finasteride | increases expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | Finasteride results in increased expression of MRPL22 mRNA | CTD | PMID:24136188 | flutamide | increases expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of MRPL22 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MRPL22 mRNA | CTD | PMID:22206623 | hydrogen peroxide | affects expression | ISO | MRPL22 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of MRPL22 mRNA | CTD | PMID:20044591 | indometacin | multiple interactions | ISO | MRPL22 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of MRPL22 mRNA | CTD | PMID:28628672 | ivermectin | increases expression | ISO | MRPL22 (Homo sapiens) | 6480464 | Ivermectin results in increased expression of MRPL22 protein | CTD | PMID:32959892 | methidathion | increases expression | EXP | | 6480464 | methidathion results in increased expression of MRPL22 mRNA | CTD | PMID:34813904 | methimazole | increases expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of MRPL22 mRNA | CTD | PMID:30047161 | methotrexate | multiple interactions | ISO | MRPL22 (Homo sapiens) | 6480464 | [Antirheumatic Agents co-treated with Methotrexate] results in decreased expression of MRPL22 mRNA | CTD | PMID:16817978 | nefazodone | increases expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | nefazodone results in increased expression of MRPL22 mRNA | CTD | PMID:24136188 | nimesulide | increases expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | nimesulide results in increased expression of MRPL22 mRNA | CTD | PMID:24136188 | oxaliplatin | multiple interactions | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of MRPL22 mRNA | CTD | PMID:25729387 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of MRPL22 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of MRPL22 mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | ISO | MRPL22 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of MRPL22 mRNA | CTD | PMID:21420995 and PMID:25704631 | pentachlorophenol | increases expression | EXP | | 6480464 | Pentachlorophenol results in increased expression of MRPL22 mRNA | CTD | PMID:23892564 | perfluorooctane-1-sulfonic acid | decreases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in decreased expression of MRPL22 protein | CTD | PMID:26178269 | propiconazole | increases expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | propiconazole results in increased expression of MRPL22 mRNA | CTD | PMID:30047161 | quercitrin | decreases expression | ISO | MRPL22 (Homo sapiens) | 6480464 | quercitrin results in decreased expression of MRPL22 mRNA | CTD | PMID:25193878 | rac-lactic acid | decreases expression | ISO | MRPL22 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of MRPL22 mRNA | CTD | PMID:30851411 | resveratrol | increases expression | EXP | | 6480464 | resveratrol results in increased expression of MRPL22 mRNA | CTD | PMID:22610192 | resveratrol | multiple interactions | ISO | MRPL22 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of MRPL22 mRNA | CTD | PMID:23557933 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of MRPL22 mRNA | CTD | PMID:16014739 | sodium arsenite | decreases activity | ISO | MRPL22 (Homo sapiens) | 6480464 | sodium arsenite results in decreased activity of MRPL22 protein | CTD | PMID:30528433 | sulfadimethoxine | increases expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of MRPL22 mRNA | CTD | PMID:30047161 | sulindac | increases expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | Sulindac results in increased expression of MRPL22 mRNA | CTD | PMID:24136188 | tolcapone | decreases expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | tolcapone results in decreased expression of MRPL22 mRNA | CTD | PMID:24136188 | topotecan | multiple interactions | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of MRPL22 mRNA | CTD | PMID:25729387 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of MRPL22 mRNA | CTD | PMID:17963808 | vinclozolin | decreases expression | ISO | Mrpl22 (Rattus norvegicus) | 6480464 | vinclozolin results in decreased expression of MRPL22 mRNA | CTD | PMID:23034163 and PMID:23555832 | |