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Gene: Pip5k1c (phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma) Mus musculus
Symbol: Pip5k1c
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma
Description: Exhibits 1-phosphatidylinositol-4-phosphate 5-kinase activity and talin binding activity. Involved in several processes, including cytoskeletal anchoring at plasma membrane; platelet aggregation; and regulation of endocytosis. Localizes to the cytosol; glutamatergic synapse; and postsynaptic density. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 3. Is expressed in alimentary system; ganglia; heart ventricle; nervous system; and sensory organ. Orthologous to human PIP5K1C (phosphatidylinositol-4-phosphate 5-kinase type 1 gamma); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; E-cadherin signaling pathway; epidermal growth factor/neuregulin signaling pathway; INTERACTS WITH (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI115456; AI835305; phosphatidylinositol 4-phosphate 5-kinase type I gamma; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma; phosphatidylinositol-4-phosphate 5-kinase type I gamma; phosphatidylinositol-4-phosphate 5-kinase type-1 gamma; PIP5K1-gamma; Pip5kIgamma; ptdIns(4)P-5-kinase 1 gamma
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381081,292,835 - 81,319,974 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371080,755,717 - 80,782,719 (+)NCBIGRCm37mm9NCBIm37
MGSCv361080,696,109 - 80,721,034 (+)NCBImm8
Celera1082,313,312 - 82,340,709 (+)NCBICelera
Cytogenetic Map10 C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pip5k1c
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1558334
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.