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Gene: Pip5k1c (phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma) Mus musculus
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Symbol: Pip5k1c
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma
Description: Exhibits 1-phosphatidylinositol-4-phosphate 5-kinase activity and talin binding activity. Involved in several processes, including cytoskeletal anchoring at plasma membrane; platelet aggregation; and regulation of endocytosis. Localizes to the cytosol; glutamatergic synapse; and postsynaptic density. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 3. Is expressed in alimentary system; ganglia; heart ventricle; nervous system; and sensory organ. Orthologous to human PIP5K1C (phosphatidylinositol-4-phosphate 5-kinase type 1 gamma); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; E-cadherin signaling pathway; epidermal growth factor/neuregulin signaling pathway; INTERACTS WITH (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI115456; AI835305; phosphatidylinositol 4-phosphate 5-kinase type I gamma; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma; phosphatidylinositol-4-phosphate 5-kinase type I gamma; phosphatidylinositol-4-phosphate 5-kinase type-1 gamma; PIP5K1-gamma; Pip5kIgamma; ptdIns(4)P-5-kinase 1 gamma
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381081,292,835 - 81,319,974 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371080,755,717 - 80,782,719 (+)NCBIGRCm37mm9NCBIm37
MGSCv361080,696,109 - 80,721,034 (+)NCBImm8
Celera1082,313,312 - 82,340,709 (+)NCBICelera
Cytogenetic Map10 C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pip5k1c
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1558334
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.