Symbol:
Phlda3
Name:
pleckstrin homology like domain, family A, member 3
RGD ID:
1321442
MGI Page
MGI
Description:
Predicted to enable phosphatidylinositol phosphate binding activity and phosphatidylinositol-3,4-bisphosphate binding activity. Predicted to be involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and positive regulation of apoptotic process. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Is expressed in several structures, including extraembryonic component; genitourinary system; hemolymphoid system; intestine; and liver. Orthologous to human PHLDA3 (pleckstrin homology like domain family A member 3).
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
pleckstrin homology-like domain family A member 3; pleckstrin homology-like domain, family A, member 3; TDAG/lpl homolog 1; TDAG51/Ipl homolog 1; Tih; Tih1
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
PHLDA3 (pleckstrin homology like domain family A member 3) HGNC
EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):
Phlda3 (pleckstrin homology-like domain, family A, member 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Phlda3 (pleckstrin homology like domain family A member 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
PHLDA3 (pleckstrin homology like domain family A member 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
PHLDA3 (pleckstrin homology like domain family A member 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Phlda3 (pleckstrin homology like domain family A member 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
PHLDA3 (pleckstrin homology like domain family A member 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
PHLDA3 (pleckstrin homology like domain family A member 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Phlda3 (pleckstrin homology like domain family A member 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
PHLDA2 (pleckstrin homology like domain family A member 2) HGNC
OrthoDB
Alliance orthologs 3
Rattus norvegicus (Norway rat):
Phlda3 (pleckstrin homology-like domain, family A, member 3)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
PHLDA3 (pleckstrin homology like domain family A member 3)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
phlda3 (pleckstrin homology-like domain, family A, member 3)
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER|PhylomeDB|ZFIN)
Latest Assembly:
GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 1 135,693,823 - 135,696,872 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 1 135,693,857 - 135,696,874 (+) Ensembl GRCm39 Ensembl GRCm38 1 135,766,085 - 135,769,134 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 1 135,766,119 - 135,769,136 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 1 137,662,662 - 137,665,711 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 1 137,582,544 - 137,585,545 (+) NCBI MGSCv36 mm8 Celera 1 138,400,219 - 138,403,272 (+) NCBI Celera Cytogenetic Map 1 E4 NCBI cM Map 1 59.26 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Phlda3 Mouse (-)-demecolcine increases expression ISO RGD:1321441 6480464 Demecolcine results in increased expression of PHLDA3 mRNA CTD PMID:23649840 Phlda3 Mouse (S)-colchicine decreases expression ISO RGD:1321441 6480464 Colchicine results in decreased expression of PHLDA3 mRNA CTD PMID:24211769 Phlda3 Mouse 1,1-dichloroethene increases expression EXP 6480464 vinylidene chloride results in increased expression of PHLDA3 mRNA CTD PMID:26682919 Phlda3 Mouse 1,2-dimethylhydrazine increases expression ISO RGD:1310502 6480464 1,2-Dimethylhydrazine results in increased expression of PHLDA3 mRNA CTD PMID:27840820 Phlda3 Mouse 1,2-dimethylhydrazine increases expression EXP 6480464 1,2-Dimethylhydrazine results in increased expression of PHLDA3 mRNA CTD PMID:22206623 Phlda3 Mouse 1,2-dimethylhydrazine multiple interactions EXP 6480464 Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PHLDA3 mRNA] CTD PMID:22206623 Phlda3 Mouse 1,4-dioxane increases expression EXP 6480464 1,4-dioxane results in increased expression of PHLDA3 mRNA CTD PMID:33693819 Phlda3 Mouse 1-nitropropane decreases expression ISO RGD:1310502 6480464 1-nitropropane results in decreased expression of PHLDA3 mRNA CTD PMID:17070881 Phlda3 Mouse 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of PHLDA3 mRNA CTD PMID:19484750 Phlda3 Mouse 17beta-estradiol increases expression ISO RGD:1310502 6480464 Estradiol results in increased expression of PHLDA3 mRNA CTD PMID:32145629 Phlda3 Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1310502 6480464 AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of PHLDA3 mRNA] CTD PMID:21215274 Phlda3 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1310502 6480464 Tetrachlorodibenzodioxin results in increased expression of PHLDA3 mRNA CTD PMID:33387578|PMID:34747641 Phlda3 Mouse 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of PHLDA3 mRNA CTD PMID:21570461|PMID:26377647 Phlda3 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PHLDA3 mRNA CTD PMID:23238561 Phlda3 Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1310502 6480464 Tetrachlorodibenzodioxin results in decreased expression of PHLDA3 mRNA CTD PMID:21215274|PMID:23238561 Phlda3 Mouse 2,4-diaminotoluene increases expression ISO RGD:1310502 6480464 2,4-diaminotoluene results in increased expression of PHLDA3 mRNA CTD PMID:17070881 Phlda3 Mouse 2,4-dinitrotoluene affects expression ISO RGD:1310502 6480464 2,4-dinitrotoluene affects the expression of PHLDA3 mRNA CTD PMID:21346803 Phlda3 Mouse 2,6-diaminotoluene decreases expression ISO RGD:1310502 6480464 2,6-diaminotoluene results in decreased expression of PHLDA3 mRNA CTD PMID:17070881 Phlda3 Mouse 2,6-dinitrotoluene affects expression ISO RGD:1310502 6480464 2,6-dinitrotoluene affects the expression of PHLDA3 mRNA CTD PMID:21346803 Phlda3 Mouse 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene results in increased expression of PHLDA3 mRNA CTD PMID:21607683 Phlda3 Mouse 2-acetamidofluorene increases expression ISO RGD:1310502 6480464 2-Acetylaminofluorene results in increased expression of PHLDA3 mRNA CTD PMID:17070881|PMID:22584684 Phlda3 Mouse 2-hydroxypropanoic acid affects expression ISO RGD:1321441 6480464 Lactic Acid affects the expression of PHLDA3 mRNA CTD PMID:30851411 Phlda3 Mouse 2-nitro-p-phenylenediamine decreases expression ISO RGD:1310502 6480464 2-nitro-4-phenylenediamine results in decreased expression of PHLDA3 mRNA CTD PMID:17070881 Phlda3 Mouse 2-nitrofluorene increases expression ISO RGD:1310502 6480464 2-nitrofluorene results in increased expression of PHLDA3 mRNA CTD PMID:22484513|PMID:23052194 Phlda3 Mouse 2-nitropropane increases expression ISO RGD:1310502 6480464 2-nitropropane results in increased expression of PHLDA3 mRNA CTD PMID:17070881 Phlda3 Mouse 4,4'-sulfonyldiphenol decreases methylation EXP 6480464 bisphenol S results in decreased methylation of PHLDA3 exon CTD PMID:33297965 Phlda3 Mouse 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression ISO RGD:1310502 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PHLDA3 mRNA CTD PMID:22484513|PMID:23052194 Phlda3 Mouse 4-acetylaminofluorene decreases expression ISO RGD:1310502 6480464 4-acetylaminofluorene results in decreased expression of PHLDA3 mRNA CTD PMID:17070881 Phlda3 Mouse 4-nitro-1,2-phenylenediamine decreases expression ISO RGD:1310502 6480464 1,2-diamino-4-nitrobenzene results in decreased expression of PHLDA3 mRNA CTD PMID:17070881 Phlda3 Mouse 5-fluorouracil increases expression ISO RGD:1321441 6480464 Fluorouracil results in increased expression of PHLDA3 mRNA CTD PMID:16557594 Phlda3 Mouse 6-propyl-2-thiouracil decreases expression ISO RGD:1310502 6480464 Propylthiouracil results in decreased expression of PHLDA3 mRNA CTD PMID:24780913 Phlda3 Mouse 7,12-dimethyltetraphene affects expression EXP 6480464 9,10-Dimethyl-1,2-benzanthracene affects the expression of PHLDA3 mRNA CTD PMID:21785161 Phlda3 Mouse 7,12-dimethyltetraphene multiple interactions EXP 6480464 [9,10-Dimethyl-1,2-benzanthracene results in increased activity of AHR protein] which results in increased expression of PHLDA3 more ... CTD PMID:32553695 Phlda3 Mouse 7,12-dimethyltetraphene increases expression EXP 6480464 9,10-Dimethyl-1,2-benzanthracene metabolite results in increased expression of PHLDA3 mRNA CTD PMID:32553695 Phlda3 Mouse acetamide increases expression ISO RGD:1310502 6480464 acetamide results in increased expression of PHLDA3 mRNA CTD PMID:31881176 Phlda3 Mouse adefovir pivoxil increases expression ISO RGD:1321441 6480464 adefovir dipivoxil results in increased expression of PHLDA3 mRNA CTD PMID:25596134 Phlda3 Mouse adenine decreases expression ISO RGD:1321441 6480464 Adenine results in decreased expression of PHLDA3 mRNA CTD PMID:24211769 Phlda3 Mouse aflatoxin B1 affects expression ISO RGD:1321441 6480464 Aflatoxin B1 affects the expression of PHLDA3 protein CTD PMID:20106945 Phlda3 Mouse aflatoxin B1 increases expression ISO RGD:1321441 6480464 Aflatoxin B1 results in increased expression of PHLDA3 mRNA CTD PMID:21632981|PMID:22100608|PMID:27153756 Phlda3 Mouse aflatoxin B1 increases expression ISO RGD:1310502 6480464 Aflatoxin B1 results in increased expression of PHLDA3 mRNA CTD PMID:22484513|PMID:23052194|PMID:23385219|PMID:23630614|PMID:25378103|PMID:33354967 Phlda3 Mouse aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of PHLDA3 mRNA CTD PMID:19770486 Phlda3 Mouse aristolochic acid A increases expression ISO RGD:1321441 6480464 aristolochic acid I results in increased expression of PHLDA3 mRNA CTD PMID:33212167 Phlda3 Mouse arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of PHLDA3 mRNA CTD PMID:29095437 Phlda3 Mouse arsenous acid multiple interactions EXP 6480464 Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of PHLDA3 mRNA] CTD PMID:29095437 Phlda3 Mouse benzene increases expression EXP 6480464 Benzene results in increased expression of PHLDA3 mRNA CTD PMID:15120971|PMID:15122651 Phlda3 Mouse benzo[a]pyrene increases expression ISO RGD:1321441 6480464 Benzo(a)pyrene results in increased expression of PHLDA3 mRNA CTD PMID:20106945|PMID:21632981|PMID:22316170|PMID:32234424 Phlda3 Mouse benzo[a]pyrene decreases methylation ISO RGD:1321441 6480464 Benzo(a)pyrene results in decreased methylation of PHLDA3 3' UTR CTD PMID:27901495 Phlda3 Mouse benzo[a]pyrene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of more ... CTD PMID:27858113 Phlda3 Mouse benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of PHLDA3 mRNA CTD PMID:19770486|PMID:21569818|PMID:21715664|PMID:21964900|PMID:22610609|PMID:25908611|PMID:32417428 Phlda3 Mouse benzo[a]pyrene affects expression EXP 6480464 Benzo(a)pyrene affects the expression of PHLDA3 mRNA CTD PMID:22342234 Phlda3 Mouse benzo[b]fluoranthene increases expression EXP 6480464 benzo(b)fluoranthene results in increased expression of PHLDA3 mRNA CTD PMID:26377693 Phlda3 Mouse benzo[b]fluoranthene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of more ... CTD PMID:27858113 Phlda3 Mouse beta-lapachone increases expression ISO RGD:1321441 6480464 beta-lapachone results in increased expression of PHLDA3 mRNA CTD PMID:38218311 Phlda3 Mouse beta-naphthoflavone multiple interactions ISO RGD:1310502 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PHLDA3 mRNA CTD PMID:18164116 Phlda3 Mouse bis(2-chloroethyl) sulfide affects expression ISO RGD:1310502 6480464 Mustard Gas affects the expression of PHLDA3 mRNA CTD PMID:15651846 Phlda3 Mouse bis(2-chloroethyl) sulfide increases expression ISO RGD:1321441 6480464 Mustard Gas results in increased expression of PHLDA3 mRNA CTD PMID:25102026 Phlda3 Mouse bis(2-ethylhexyl) phthalate decreases expression ISO RGD:1310502 6480464 Diethylhexyl Phthalate results in decreased expression of PHLDA3 mRNA CTD PMID:22584684 Phlda3 Mouse bisphenol A affects expression ISO RGD:1310502 6480464 bisphenol A affects the expression of PHLDA3 mRNA CTD PMID:25181051 Phlda3 Mouse bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PHLDA3 mRNA CTD PMID:35598803 Phlda3 Mouse bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PHLDA3 mRNA CTD PMID:32156529|PMID:35479511 Phlda3 Mouse bisphenol A increases expression ISO RGD:1310502 6480464 bisphenol A results in increased expression of PHLDA3 mRNA CTD PMID:32145629 Phlda3 Mouse buta-1,3-diene increases expression EXP 6480464 1,3-butadiene results in increased expression of PHLDA3 mRNA CTD PMID:29038090 Phlda3 Mouse butan-1-ol multiple interactions ISO RGD:1321441 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic more ... CTD PMID:29432896 Phlda3 Mouse cadmium dichloride increases expression ISO RGD:1321441 6480464 Cadmium Chloride results in increased expression of PHLDA3 mRNA CTD PMID:25596134 Phlda3 Mouse cadmium dichloride decreases expression ISO RGD:1321441 6480464 Cadmium Chloride results in decreased expression of PHLDA3 mRNA CTD PMID:38568856 Phlda3 Mouse cadmium sulfate increases expression EXP 6480464 cadmium sulfate results in increased expression of PHLDA3 mRNA CTD PMID:19274763 Phlda3 Mouse caffeine increases phosphorylation ISO RGD:1321441 6480464 Caffeine results in increased phosphorylation of PHLDA3 protein CTD PMID:35688186 Phlda3 Mouse carbamazepine affects expression ISO RGD:1321441 6480464 Carbamazepine affects the expression of PHLDA3 mRNA CTD PMID:25979313 Phlda3 Mouse carbon nanotube increases expression EXP 6480464 Nanotubes, Carbon analog results in increased expression of PHLDA3 mRNA; Nanotubes, Carbon results in increased more ... CTD PMID:25554681 Phlda3 Mouse chloroacetaldehyde increases expression ISO RGD:1321441 6480464 chloroacetaldehyde results in increased expression of PHLDA3 mRNA CTD PMID:25596134 Phlda3 Mouse choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... CTD PMID:20938992 Phlda3 Mouse chromium(6+) multiple interactions ISO RGD:1321441 6480464 [zinc chromate results in increased abundance of chromium hexavalent ion] which results in increased expression more ... CTD PMID:38479592 Phlda3 Mouse chrysene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of more ... CTD PMID:27858113 Phlda3 Mouse cidofovir anhydrous increases expression ISO RGD:1321441 6480464 Cidofovir results in increased expression of PHLDA3 mRNA CTD PMID:25596134 Phlda3 Mouse cisplatin increases expression ISO RGD:1321441 6480464 Cisplatin results in increased expression of PHLDA3 mRNA CTD PMID:24280081|PMID:25596134|PMID:33545341 Phlda3 Mouse cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of PHLDA3 mRNA CTD PMID:24280081|PMID:25270620 Phlda3 Mouse cobalt atom multiple interactions ISO RGD:1321441 6480464 [tungsten carbide co-treated with Cobalt] results in increased expression of PHLDA3 mRNA CTD PMID:23052192 Phlda3 Mouse cobalt dichloride increases expression ISO RGD:1321441 6480464 cobaltous chloride results in increased expression of PHLDA3 mRNA CTD PMID:19376846 Phlda3 Mouse cocaine affects expression ISO RGD:1310502 6480464 Cocaine affects the expression of PHLDA3 mRNA CTD PMID:20187946 Phlda3 Mouse copper(II) chloride increases expression ISO RGD:1321441 6480464 cupric chloride results in increased expression of PHLDA3 mRNA CTD PMID:38568856 Phlda3 Mouse copper(II) sulfate decreases expression ISO RGD:1321441 6480464 Copper Sulfate results in decreased expression of PHLDA3 mRNA CTD PMID:19549813 Phlda3 Mouse Cuprizon increases expression ISO RGD:1310502 6480464 Cuprizone results in increased expression of PHLDA3 mRNA CTD PMID:27523638 Phlda3 Mouse cyclosporin A increases expression ISO RGD:1321441 6480464 Cyclosporine results in increased expression of PHLDA3 mRNA CTD PMID:20106945|PMID:22147139|PMID:25596134 Phlda3 Mouse deoxynivalenol increases expression ISO RGD:1321441 6480464 deoxynivalenol results in increased expression of PHLDA3 mRNA CTD PMID:31863870 Phlda3 Mouse dexamethasone increases expression ISO RGD:1310502 6480464 Dexamethasone results in increased expression of PHLDA3 mRNA CTD PMID:20032058 Phlda3 Mouse dexamethasone multiple interactions ISO RGD:1310502 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of PHLDA3 mRNA] CTD PMID:20032058 Phlda3 Mouse diarsenic trioxide multiple interactions EXP 6480464 Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of PHLDA3 mRNA] CTD PMID:29095437 Phlda3 Mouse diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of PHLDA3 mRNA CTD PMID:29095437 Phlda3 Mouse dibenz[a,h]anthracene increases expression EXP 6480464 1,2,5,6-dibenzanthracene results in increased expression of PHLDA3 mRNA CTD PMID:26377693 Phlda3 Mouse Dibutyl phosphate affects expression ISO RGD:1321441 6480464 di-n-butylphosphoric acid affects the expression of PHLDA3 mRNA CTD PMID:37042841 Phlda3 Mouse dibutyl phthalate increases expression ISO RGD:1310502 6480464 Dibutyl Phthalate results in increased expression of PHLDA3 mRNA CTD PMID:21266533 Phlda3 Mouse diclofenac increases expression EXP 6480464 Diclofenac results in increased expression of PHLDA3 mRNA CTD PMID:35537566 Phlda3 Mouse dioxygen increases expression ISO RGD:1321441 6480464 Oxygen deficiency results in increased expression of PHLDA3 mRNA CTD PMID:25596134 Phlda3 Mouse dioxygen multiple interactions ISO RGD:1310502 6480464 [[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results more ... CTD PMID:34351043 Phlda3 Mouse dioxygen multiple interactions EXP 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of PHLDA3 mRNA CTD PMID:30529165 Phlda3 Mouse dorsomorphin multiple interactions ISO RGD:1321441 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Phlda3 Mouse doxorubicin increases expression ISO RGD:1321441 6480464 Doxorubicin results in increased expression of PHLDA3 mRNA CTD PMID:29803840 Phlda3 Mouse doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of PHLDA3 mRNA CTD PMID:36227756 Phlda3 Mouse ethyl methanesulfonate increases expression ISO RGD:1321441 6480464 Ethyl Methanesulfonate results in increased expression of PHLDA3 mRNA CTD PMID:23649840 Phlda3 Mouse etoposide increases expression EXP 6480464 Etoposide results in increased expression of PHLDA3 mRNA CTD PMID:25270620 Phlda3 Mouse fenamidone increases expression EXP 6480464 fenamidone results in increased expression of PHLDA3 mRNA CTD PMID:27029645 Phlda3 Mouse fenofibrate affects expression ISO RGD:1310502 6480464 Fenofibrate affects the expression of PHLDA3 mRNA CTD PMID:25596134 Phlda3 Mouse folic acid multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... CTD PMID:20938992|PMID:22206623 Phlda3 Mouse formaldehyde increases expression ISO RGD:1321441 6480464 Formaldehyde results in increased expression of PHLDA3 mRNA CTD PMID:23649840 Phlda3 Mouse furan increases expression EXP 6480464 furan results in increased expression of PHLDA3 mRNA CTD PMID:24183702 Phlda3 Mouse Heptachlor epoxide decreases expression EXP 6480464 Heptachlor Epoxide results in decreased expression of PHLDA3 mRNA CTD PMID:25270620 Phlda3 Mouse hydroxyurea increases expression ISO RGD:1321441 6480464 Hydroxyurea results in increased expression of PHLDA3 mRNA CTD PMID:24211769 Phlda3 Mouse ifosfamide increases expression ISO RGD:1321441 6480464 Ifosfamide results in increased expression of PHLDA3 mRNA CTD PMID:25596134 Phlda3 Mouse indoline multiple interactions ISO RGD:1310502 6480464 [Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein inhibits the reaction [[Oxygen more ... CTD PMID:34351043 Phlda3 Mouse inulin multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of PHLDA3 mRNA CTD PMID:36331819 Phlda3 Mouse iron dichloride decreases expression ISO RGD:1321441 6480464 ferrous chloride results in decreased expression of PHLDA3 mRNA CTD PMID:35984750 Phlda3 Mouse iron(III) nitrilotriacetate increases expression ISO RGD:1310502 6480464 ferric nitrilotriacetate results in increased expression of PHLDA3 mRNA CTD PMID:23208426 Phlda3 Mouse isoprenaline decreases expression EXP 6480464 Isoproterenol results in decreased expression of PHLDA3 mRNA CTD PMID:21335049 Phlda3 Mouse L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... CTD PMID:20938992 Phlda3 Mouse lead(0) affects expression ISO RGD:1321441 6480464 Lead affects the expression of PHLDA3 mRNA CTD PMID:28903495 Phlda3 Mouse leflunomide decreases expression ISO RGD:1321441 6480464 leflunomide results in decreased expression of PHLDA3 mRNA CTD PMID:28988120 Phlda3 Mouse leflunomide increases expression EXP 6480464 leflunomide results in increased expression of PHLDA3 mRNA CTD PMID:19751817 Phlda3 Mouse leflunomide decreases expression ISO RGD:1310502 6480464 leflunomide results in decreased expression of PHLDA3 mRNA CTD PMID:24136188 Phlda3 Mouse linezolid decreases expression ISO RGD:1310502 6480464 Linezolid results in decreased expression of PHLDA3 mRNA CTD PMID:21296123 Phlda3 Mouse lipopolysaccharide multiple interactions ISO RGD:1321441 6480464 [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of PHLDA3 mRNA; [S-(1,2-dichlorovinyl)cysteine more ... CTD PMID:35811015 Phlda3 Mouse manganese(II) chloride increases expression ISO RGD:1310502 6480464 manganese chloride results in increased expression of PHLDA3 mRNA CTD PMID:28801915 Phlda3 Mouse metformin increases expression ISO RGD:1310502 6480464 Metformin results in increased expression of PHLDA3 mRNA CTD PMID:25596134 Phlda3 Mouse metformin multiple interactions EXP 6480464 Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of PHLDA3 mRNA] CTD PMID:29095437 Phlda3 Mouse methapyrilene increases expression ISO RGD:1310502 6480464 Methapyrilene results in increased expression of PHLDA3 mRNA CTD PMID:30467583 Phlda3 Mouse methyl methanesulfonate increases expression ISO RGD:1321441 6480464 Methyl Methanesulfonate results in increased expression of PHLDA3 mRNA CTD PMID:23649840 Phlda3 Mouse mitomycin C increases expression EXP 6480464 Mitomycin results in increased expression of PHLDA3 mRNA CTD PMID:25270620 Phlda3 Mouse MK-2206 multiple interactions ISO RGD:1310502 6480464 MK 2206 inhibits the reaction [PHLDA3 protein inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] more ... CTD PMID:34351043 Phlda3 Mouse N-methyl-4-phenylpyridinium increases expression ISO RGD:1321441 6480464 1-Methyl-4-phenylpyridinium results in increased expression of PHLDA3 mRNA CTD PMID:24810058 Phlda3 Mouse N-methyl-4-phenylpyridinium increases expression ISO RGD:1310502 6480464 1-Methyl-4-phenylpyridinium results in increased expression of PHLDA3 mRNA CTD PMID:28801915 Phlda3 Mouse N-methyl-N-nitrosourea increases expression EXP 6480464 Methylnitrosourea results in increased expression of PHLDA3 mRNA CTD PMID:25270620 Phlda3 Mouse N-nitrosodiethylamine multiple interactions ISO RGD:1310502 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PHLDA3 mRNA CTD PMID:18164116 Phlda3 Mouse N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of PHLDA3 mRNA CTD PMID:21607683|PMID:24535843 Phlda3 Mouse N-Nitrosopyrrolidine increases expression ISO RGD:1321441 6480464 N-Nitrosopyrrolidine results in increased expression of PHLDA3 mRNA CTD PMID:32234424 Phlda3 Mouse nitrates multiple interactions EXP 6480464 [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of PHLDA3 more ... CTD PMID:35964746 Phlda3 Mouse ochratoxin A increases expression ISO RGD:1310502 6480464 ochratoxin A results in increased expression of PHLDA3 mRNA CTD PMID:23208426|PMID:23358140 Phlda3 Mouse orphenadrine affects expression ISO RGD:1310502 6480464 Orphenadrine affects the expression of PHLDA3 mRNA CTD PMID:23665939 Phlda3 Mouse oxaliplatin increases expression ISO RGD:1310502 6480464 oxaliplatin results in increased expression of PHLDA3 mRNA CTD PMID:25729387 Phlda3 Mouse oxaliplatin multiple interactions ISO RGD:1310502 6480464 [Topotecan co-treated with oxaliplatin] results in increased expression of PHLDA3 mRNA CTD PMID:25729387 Phlda3 Mouse paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of PHLDA3 mRNA CTD PMID:17562736 Phlda3 Mouse paracetamol increases expression ISO RGD:1310502 6480464 Acetaminophen results in increased expression of PHLDA3 mRNA CTD PMID:33387578 Phlda3 Mouse paracetamol increases expression ISO RGD:1321441 6480464 Acetaminophen results in increased expression of PHLDA3 mRNA CTD PMID:29067470 Phlda3 Mouse paracetamol decreases expression ISO RGD:1310502 6480464 Acetaminophen results in decreased expression of PHLDA3 mRNA CTD PMID:32479839 Phlda3 Mouse paraquat increases expression ISO RGD:1310502 6480464 Paraquat results in increased expression of PHLDA3 mRNA CTD PMID:32680482 Phlda3 Mouse perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of PHLDA3 mRNA CTD PMID:36331819 Phlda3 Mouse phenobarbital multiple interactions EXP 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of PHLDA3 mRNA] CTD PMID:19482888 Phlda3 Mouse phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of PHLDA3 mRNA CTD PMID:19482888 Phlda3 Mouse phenylmercury acetate increases expression ISO RGD:1321441 6480464 Phenylmercuric Acetate results in increased expression of PHLDA3 mRNA CTD PMID:26272509 Phlda3 Mouse phenylmercury acetate multiple interactions ISO RGD:1321441 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Phlda3 Mouse pinostrobin increases expression ISO RGD:1321441 6480464 pinostrobin results in increased expression of PHLDA3 mRNA CTD PMID:37777166 Phlda3 Mouse pirinixic acid multiple interactions ISO RGD:1321441 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... CTD PMID:19710929 Phlda3 Mouse pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of PHLDA3 mRNA CTD PMID:23811191 Phlda3 Mouse propanal increases expression ISO RGD:1321441 6480464 propionaldehyde results in increased expression of PHLDA3 mRNA CTD PMID:26079696 Phlda3 Mouse quercetin increases expression ISO RGD:1321441 6480464 Quercetin results in increased expression of PHLDA3 mRNA CTD PMID:21632981 Phlda3 Mouse rac-lactic acid affects expression ISO RGD:1321441 6480464 Lactic Acid affects the expression of PHLDA3 mRNA CTD PMID:30851411 Phlda3 Mouse resveratrol multiple interactions ISO RGD:1321441 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of PHLDA3 mRNA CTD PMID:23557933 Phlda3 Mouse S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO RGD:1321441 6480464 [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of PHLDA3 mRNA; [S-(1,2-dichlorovinyl)cysteine more ... CTD PMID:35811015 Phlda3 Mouse SB 431542 multiple interactions ISO RGD:1321441 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Phlda3 Mouse sodium arsenite increases expression ISO RGD:1321441 6480464 sodium arsenite results in increased expression of PHLDA3 mRNA CTD PMID:38568856 Phlda3 Mouse sodium dichromate affects expression ISO RGD:1310502 6480464 sodium bichromate affects the expression of PHLDA3 mRNA CTD PMID:22110744 Phlda3 Mouse Soman increases expression ISO RGD:1310502 6480464 Soman results in increased expression of PHLDA3 mRNA CTD PMID:19281266 Phlda3 Mouse tamoxifen increases expression EXP 6480464 Tamoxifen results in increased expression of PHLDA3 mRNA CTD PMID:25123088 Phlda3 Mouse temozolomide decreases expression ISO RGD:1321441 6480464 Temozolomide results in decreased expression of PHLDA3 mRNA CTD PMID:31758290 Phlda3 Mouse testosterone increases expression EXP 6480464 Testosterone results in increased expression of PHLDA3 mRNA CTD PMID:20403060 Phlda3 Mouse testosterone multiple interactions ISO RGD:1310502 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of PHLDA3 mRNA] CTD PMID:20032058 Phlda3 Mouse tetrachloromethane increases expression ISO RGD:1310502 6480464 Carbon Tetrachloride results in increased expression of PHLDA3 mRNA CTD PMID:31150632 Phlda3 Mouse tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of PHLDA3 mRNA CTD PMID:31919559 Phlda3 Mouse tetraphene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of more ... CTD PMID:27858113 Phlda3 Mouse thiazoles multiple interactions ISO RGD:1310502 6480464 [Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein inhibits the reaction [[Oxygen more ... CTD PMID:34351043 Phlda3 Mouse thioacetamide increases expression ISO RGD:1310502 6480464 Thioacetamide results in increased expression of PHLDA3 mRNA CTD PMID:23411599|PMID:34492290 Phlda3 Mouse titanium dioxide decreases methylation EXP 6480464 titanium dioxide results in decreased methylation of PHLDA3 gene; titanium dioxide results in decreased methylation more ... CTD PMID:35295148 Phlda3 Mouse topotecan increases expression ISO RGD:1310502 6480464 Topotecan results in increased expression of PHLDA3 mRNA CTD PMID:25729387 Phlda3 Mouse topotecan multiple interactions ISO RGD:1310502 6480464 [Topotecan co-treated with oxaliplatin] results in increased expression of PHLDA3 mRNA CTD PMID:25729387 Phlda3 Mouse trichloroethene increases expression ISO RGD:1310502 6480464 Trichloroethylene results in increased expression of PHLDA3 mRNA CTD PMID:33387578 Phlda3 Mouse triphenyl phosphate decreases expression ISO RGD:1310502 6480464 triphenyl phosphate results in decreased expression of PHLDA3 mRNA CTD PMID:30589522 Phlda3 Mouse Triptolide increases expression EXP 6480464 triptolide results in increased expression of PHLDA3 mRNA CTD PMID:32835833 Phlda3 Mouse trovafloxacin increases expression EXP 6480464 trovafloxacin results in increased expression of PHLDA3 mRNA CTD PMID:35537566 Phlda3 Mouse Tungsten carbide multiple interactions ISO RGD:1321441 6480464 [tungsten carbide co-treated with Cobalt] results in increased expression of PHLDA3 mRNA CTD PMID:23052192 Phlda3 Mouse tunicamycin increases expression ISO RGD:1321441 6480464 Tunicamycin results in increased expression of PHLDA3 mRNA CTD PMID:22378314 Phlda3 Mouse urethane decreases expression ISO RGD:1321441 6480464 Urethane results in decreased expression of PHLDA3 mRNA CTD PMID:28818685 Phlda3 Mouse valdecoxib decreases expression ISO RGD:1310502 6480464 valdecoxib results in decreased expression of PHLDA3 mRNA CTD PMID:24136188 Phlda3 Mouse valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of PHLDA3 mRNA CTD PMID:19136453 Phlda3 Mouse valproic acid decreases expression ISO RGD:1321441 6480464 Valproic Acid results in decreased expression of PHLDA3 mRNA CTD PMID:29154799 Phlda3 Mouse vinclozolin increases expression ISO RGD:1310502 6480464 vinclozolin results in increased expression of PHLDA3 mRNA CTD PMID:22570695 Phlda3 Mouse vinclozolin decreases expression ISO RGD:1310502 6480464 vinclozolin results in decreased expression of PHLDA3 mRNA CTD PMID:20566332 Phlda3 Mouse zoledronic acid decreases expression ISO RGD:1321441 6480464 zoledronic acid results in decreased expression of PHLDA3 mRNA CTD PMID:25596134
Molecular Function
Only show annotations with direct experimental evidence (0 objects hidden)
Phlda3 Mouse phosphatidylinositol-3,4,5-trisphosphate binding enables ISO UniProtKB:Q9Y5J5 2290270 GO_Central GO_REF:0000119 Phlda3 Mouse phosphatidylinositol-3,4,5-trisphosphate binding enables ISS UniProtKB:Q9Y5J5 2290270 UniProt GO_REF:0000024 Phlda3 Mouse phosphatidylinositol-3,4-bisphosphate binding enables ISO UniProtKB:Q9Y5J5 2290270 GO_Central GO_REF:0000119 Phlda3 Mouse phosphatidylinositol-3,4-bisphosphate binding enables ISS UniProtKB:Q9Y5J5 2290270 UniProt GO_REF:0000024 Phlda3 Mouse phosphatidylinositol-3,5-bisphosphate binding enables ISO UniProtKB:Q9Y5J5 2290270 GO_Central GO_REF:0000119 Phlda3 Mouse phosphatidylinositol-3,5-bisphosphate binding enables ISS UniProtKB:Q9Y5J5 2290270 UniProt GO_REF:0000024 Phlda3 Mouse phosphatidylinositol-3-phosphate binding enables ISS UniProtKB:Q9Y5J5 2290270 UniProt GO_REF:0000024 Phlda3 Mouse phosphatidylinositol-3-phosphate binding enables ISO UniProtKB:Q9Y5J5 2290270 GO_Central GO_REF:0000119 Phlda3 Mouse phosphatidylinositol-4,5-bisphosphate binding enables ISS UniProtKB:Q9Y5J5 2290270 UniProt GO_REF:0000024 Phlda3 Mouse phosphatidylinositol-4,5-bisphosphate binding enables ISO UniProtKB:Q9Y5J5 2290270 GO_Central GO_REF:0000119 Phlda3 Mouse phosphatidylinositol-5-phosphate binding enables ISO UniProtKB:Q9Y5J5 2290270 GO_Central GO_REF:0000119 Phlda3 Mouse phosphatidylinositol-5-phosphate binding enables ISS UniProtKB:Q9Y5J5 2290270 UniProt GO_REF:0000024
(-)-demecolcine (ISO) (S)-colchicine (ISO) 1,1-dichloroethene (EXP) 1,2-dimethylhydrazine (EXP,ISO) 1,4-dioxane (EXP) 1-nitropropane (ISO) 17beta-estradiol (EXP,ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,4-diaminotoluene (ISO) 2,4-dinitrotoluene (ISO) 2,6-diaminotoluene (ISO) 2,6-dinitrotoluene (ISO) 2-acetamidofluorene (EXP,ISO) 2-hydroxypropanoic acid (ISO) 2-nitro-p-phenylenediamine (ISO) 2-nitrofluorene (ISO) 2-nitropropane (ISO) 4,4'-sulfonyldiphenol (EXP) 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one (ISO) 4-acetylaminofluorene (ISO) 4-nitro-1,2-phenylenediamine (ISO) 5-fluorouracil (ISO) 6-propyl-2-thiouracil (ISO) 7,12-dimethyltetraphene (EXP) acetamide (ISO) adefovir pivoxil (ISO) adenine (ISO) aflatoxin B1 (EXP,ISO) aristolochic acid A (ISO) arsenous acid (EXP) benzene (EXP) benzo[a]pyrene (EXP,ISO) benzo[b]fluoranthene (EXP) beta-lapachone (ISO) beta-naphthoflavone (ISO) bis(2-chloroethyl) sulfide (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) buta-1,3-diene (EXP) butan-1-ol (ISO) cadmium dichloride (ISO) cadmium sulfate (EXP) caffeine (ISO) carbamazepine (ISO) carbon nanotube (EXP) chloroacetaldehyde (ISO) choline (EXP) chromium(6+) (ISO) chrysene (EXP) cidofovir anhydrous (ISO) cisplatin (EXP,ISO) cobalt atom (ISO) cobalt dichloride (ISO) cocaine (ISO) copper(II) chloride (ISO) copper(II) sulfate (ISO) Cuprizon (ISO) cyclosporin A (ISO) deoxynivalenol (ISO) dexamethasone (ISO) diarsenic trioxide (EXP) dibenz[a,h]anthracene (EXP) Dibutyl phosphate (ISO) dibutyl phthalate (ISO) diclofenac (EXP) dioxygen (EXP,ISO) dorsomorphin (ISO) doxorubicin (EXP,ISO) ethyl methanesulfonate (ISO) etoposide (EXP) fenamidone (EXP) fenofibrate (ISO) folic acid (EXP) formaldehyde (ISO) furan (EXP) Heptachlor epoxide (EXP) hydroxyurea (ISO) ifosfamide (ISO) indoline (ISO) inulin (EXP) iron dichloride (ISO) iron(III) nitrilotriacetate (ISO) isoprenaline (EXP) L-methionine (EXP) lead(0) (ISO) leflunomide (EXP,ISO) linezolid (ISO) lipopolysaccharide (ISO) manganese(II) chloride (ISO) metformin (EXP,ISO) methapyrilene (ISO) methyl methanesulfonate (ISO) mitomycin C (EXP) MK-2206 (ISO) N-methyl-4-phenylpyridinium (ISO) N-methyl-N-nitrosourea (EXP) N-nitrosodiethylamine (EXP,ISO) N-Nitrosopyrrolidine (ISO) nitrates (EXP) ochratoxin A (ISO) orphenadrine (ISO) oxaliplatin (ISO) paracetamol (EXP,ISO) paraquat (ISO) perfluorooctane-1-sulfonic acid (EXP) phenobarbital (EXP) phenylmercury acetate (ISO) pinostrobin (ISO) pirinixic acid (EXP,ISO) propanal (ISO) quercetin (ISO) rac-lactic acid (ISO) resveratrol (ISO) S-(1,2-dichlorovinyl)-L-cysteine (ISO) SB 431542 (ISO) sodium arsenite (ISO) sodium dichromate (ISO) Soman (ISO) tamoxifen (EXP) temozolomide (ISO) testosterone (EXP,ISO) tetrachloromethane (EXP,ISO) tetraphene (EXP) thiazoles (ISO) thioacetamide (ISO) titanium dioxide (EXP) topotecan (ISO) trichloroethene (ISO) triphenyl phosphate (ISO) Triptolide (EXP) trovafloxacin (EXP) Tungsten carbide (ISO) tunicamycin (ISO) urethane (ISO) valdecoxib (ISO) valproic acid (EXP,ISO) vinclozolin (ISO) zoledronic acid (ISO)
Molecular Function
phosphatidylinositol-3,4,5-trisphosphate binding (ISO,ISS) phosphatidylinositol-3,4-bisphosphate binding (ISO,ISS) phosphatidylinositol-3,5-bisphosphate binding (ISO,ISS) phosphatidylinositol-3-phosphate binding (ISO,ISS) phosphatidylinositol-4,5-bisphosphate binding (ISO,ISS) phosphatidylinositol-5-phosphate binding (ISO,ISS)
Phlda3 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 1 135,693,823 - 135,696,872 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 1 135,693,857 - 135,696,874 (+) Ensembl GRCm39 Ensembl GRCm38 1 135,766,085 - 135,769,134 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 1 135,766,119 - 135,769,136 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 1 137,662,662 - 137,665,711 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 1 137,582,544 - 137,585,545 (+) NCBI MGSCv36 mm8 Celera 1 138,400,219 - 138,403,272 (+) NCBI Celera Cytogenetic Map 1 E4 NCBI cM Map 1 59.26 NCBI
PHLDA3 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 1 201,464,278 - 201,469,188 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 1 201,464,278 - 201,469,237 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 1 201,433,406 - 201,438,316 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 1 199,701,245 - 199,704,922 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 1 198,166,279 - 198,169,956 NCBI Celera 1 174,558,492 - 174,562,169 (-) NCBI Celera Cytogenetic Map 1 q32.1 NCBI HuRef 1 172,600,628 - 172,604,316 (-) NCBI HuRef CHM1_1 1 202,856,735 - 202,860,431 (-) NCBI CHM1_1 T2T-CHM13v2.0 1 200,722,059 - 200,726,971 (-) NCBI T2T-CHM13v2.0
Phlda3 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 13 49,745,003 - 49,748,088 (+) NCBI GRCr8 mRatBN7.2 13 47,193,250 - 47,196,335 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 13 47,193,086 - 47,196,335 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 13 49,802,074 - 49,805,158 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 13 51,090,139 - 51,093,225 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 13 48,353,354 - 48,356,441 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 13 52,588,917 - 52,592,002 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 13 52,588,917 - 52,592,001 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 13 57,637,217 - 57,640,302 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 13 48,789,678 - 48,793,999 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 13 48,803,734 - 48,808,041 (+) NCBI Celera 13 47,510,714 - 47,513,799 (+) NCBI Celera Cytogenetic Map 13 q13 NCBI
Phlda3 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955406 37,579,006 - 37,582,230 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955406 37,579,006 - 37,582,230 (-) NCBI ChiLan1.0 ChiLan1.0
PHLDA3 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 1 47,912,241 - 47,916,187 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 1 47,876,910 - 47,880,873 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 1 177,063,775 - 177,067,714 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 1 181,365,063 - 181,368,638 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 1 181,367,976 - 181,368,359 (-) Ensembl panpan1.1 panPan2
PHLDA3 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 7 1,438,539 - 1,440,701 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 7 1,488,304 - 1,490,785 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 7 1,444,885 - 1,447,366 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 7 1,444,921 - 1,445,304 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 7 1,432,439 - 1,434,920 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 7 1,540,393 - 1,542,879 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 7 1,564,820 - 1,567,301 (+) NCBI UU_Cfam_GSD_1.0
Phlda3 Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024409344 73,746,903 - 73,750,232 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936567 2,981,602 - 2,984,903 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936567 2,981,632 - 2,984,906 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
PHLDA3 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 10 23,826,874 - 23,827,245 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 10 23,824,181 - 23,827,428 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 10 28,232,722 - 28,235,987 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
PHLDA3 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 25 27,945,013 - 27,948,870 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 25 27,945,608 - 27,945,991 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666055 28,740,957 - 28,744,831 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Phlda3
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Predicted Target Of
Count of predictions: 570 Count of miRNA genes: 382 Interacting mature miRNAs: 426 Transcripts: ENSMUST00000038945, ENSMUST00000136445 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
11039528 Ccc3_m colitis susceptibility in the Collaborative Cross 3 (mouse) 1 3680142 195051546 Mouse 27095901 Scvln8_m sacral vertebrae length 2, 10 week (mouse) 1 94127725 172027567 Mouse 1302098 Eila1_m ethanol induced locomotor activity 1 (mouse) Not determined 1 112008822 175468938 Mouse 1302161 Exq2_m exploratory and excitability QTL 2 (mouse) Not determined 1 118099720 152099816 Mouse 27226779 Tibl1_m tibia length 1, 5 week (mouse) 1 95527725 162027569 Mouse 27226714 Metcl1_m metatarsal-calcaneal length 1, 5 week (mouse) 1 121727729 139727738 Mouse 14746980 Manh50_m mandible shape 50 (mouse) 1 134131564 168131564 Mouse 10412185 Hcs9_m hepatocarcinogenesis susceptibility 9 (mouse) Not determined 1 63854690 189303617 Mouse 1301979 Melm1_m melanoma modifier 1 (mouse) Not determined 1 109638262 143638479 Mouse 1301722 Cia9_m collagen induced arthritis QTL 9 (mouse) Not determined 1 45783900 189303617 Mouse 13824984 Twq5_m testis weight QTL 5 (mouse) 1 3069992 184732197 Mouse 1301149 Lrnx12_m learning-contextual 12 (mouse) Not determined 1 112008822 168186402 Mouse 27226767 Tibl10_m tibia length 10, 10 week (mouse) 1 121727729 164827569 Mouse 12790994 Aaaq1_m aortic arch angle QTL 1 (mouse) 1 109495943 143495943 Mouse 10045640 Jckm4_m juvenile cystic kidney modifier 4 (mouse) Not determined 1 116290836 150290937 Mouse 1301249 Sbw1_m splenomegaly-NZB x NZW 1 (mouse) Not determined 1 112131005 146131085 Mouse 1301193 Lxw3_m lupus BXSB x NZW 3 (mouse) Not determined 1 102968534 136968667 Mouse 1558860 W10q7_m weight 10 weeks QTL 7 (mouse) Not determined 1 34760138 150193871 Mouse 10412162 Nobq3_m New Zealand obese QTL 3 (mouse) Not determined 1 103933405 191225397 Mouse 12880408 V125Dq3_m vitamin D active form serum level QTL 3 (mouse) 1 122927738 156927738 Mouse 27095935 Ulnl5_m ulna length 5, 10 week (mouse) 1 128727737 181327565 Mouse 1302128 Ity3_m immunity to S. typhimurium 3 (mouse) Not determined 11 131156308 165139464 Mouse 1357488 Splq3_m spleen weight QTL 3 (mouse) Not determined 1 34760138 150193871 Mouse 4141914 Gcsfis_m G-CSF induced splenomegaly (mouse) Not determined 74516235 148715579 Mouse 27095928 Pglq6_m pelvic girdle length QTL 6, 10 week (mouse) 1 75976637 148775742 Mouse 27226743 Metcl7_m metatarsal-calcaneal length 7, 10 week (mouse) 1 121727729 153875746 Mouse 27226740 Metcl13_m metatarsal-calcaneal length 13, 16 week (mouse) 1 121727729 153775746 Mouse 4142291 Aec2_m autoimmune exocrinopathy 2 (mouse) Not determined 52457737 182250592 Mouse 1357753 Kidq2_m kidney weight QTL 2 (mouse) Not determined 1 34760138 150193871 Mouse 1300989 Lrdg1_m light induced retinal degeneration 1 (mouse) Not determined 1 73755175 147125370 Mouse 27226799 Feml5_m femur length 5, 5 week (mouse) 1 122027729 164827569 Mouse 13504831 Bacszq1_m baculum size QTL 1 (mouse) 1 134331161 148128608 Mouse 27095913 Scvln2_m sacral vertebrae length 2, 5 week (mouse) 1 94127725 148775742 Mouse 1357600 Obq17_m obesity QTL 17 (mouse) Not determined 1 110553179 144553298 Mouse 1301350 Nidd4k_m Nidd4 on KK-A (mouse) Not determined 7 82291982 147125370 Mouse 27095915 Scvln13_m sacral vertebrae length 2, 16 week (mouse) 1 117527730 179827565 Mouse 1300841 Ssial1_m susceptibility to sialadenitis 1 (mouse) Not determined 1 63920002 153557562 Mouse 26884448 Sklq1_m skull length QTL 1, 5 week (mouse) 1 75976637 181327565 Mouse 1301608 Emo3_m emotionality 3 (mouse) Not determined 1 129130858 163130993 Mouse 10401248 Bglu12_m blood glucose level 12 (mouse) Not determined 1 110553179 144553298 Mouse
RH133254
Mouse Assembly Chr Position (strand) Source JBrowse GRCm38 1 135,768,880 - 135,769,092 UniSTS GRCm38 MGSCv37 1 137,665,457 - 137,665,669 UniSTS GRCm37 Celera 1 138,403,019 - 138,403,230 UniSTS Cytogenetic Map 1 E4 UniSTS cM Map 1 75.0 UniSTS
AF151099
Mouse Assembly Chr Position (strand) Source JBrowse GRCm38 1 135,766,895 - 135,767,005 UniSTS GRCm38 MGSCv37 1 137,663,472 - 137,663,582 UniSTS GRCm37 Celera 1 138,401,029 - 138,401,139 UniSTS Cytogenetic Map 1 E4 UniSTS cM Map 1 75.0 UniSTS Whitehead/MRC_RH 1 1929.69 UniSTS
Phlda3
Mouse Assembly Chr Position (strand) Source JBrowse Cytogenetic Map 1 E4 UniSTS cM Map 1 75.0 UniSTS
Phlda3
Mouse Assembly Chr Position (strand) Source JBrowse Cytogenetic Map 1 E4 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
Ensembl Acc Id:
ENSMUST00000038945 ⟹ ENSMUSP00000040614
Type:
CODING
Position:
Mouse Assembly Chr Position (strand) Source GRCm39 Ensembl 1 135,693,857 - 135,696,874 (+) Ensembl GRCm38.p6 Ensembl 1 135,766,119 - 135,769,136 (+) Ensembl
Ensembl Acc Id:
ENSMUST00000136445
Type:
CODING
Position:
Mouse Assembly Chr Position (strand) Source GRCm39 Ensembl 1 135,694,872 - 135,696,660 (+) Ensembl GRCm38.p6 Ensembl 1 135,767,134 - 135,768,922 (+) Ensembl
RefSeq Acc Id:
NM_013750 ⟹ NP_038778
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Mouse Assembly Chr Position (strand) Source GRCm39 1 135,693,823 - 135,696,872 (+) NCBI GRCm38 1 135,766,085 - 135,769,134 (+) ENTREZGENE MGSCv37 1 137,662,662 - 137,665,711 (+) RGD Celera 1 138,400,219 - 138,403,272 (+) RGD cM Map 1 ENTREZGENE
Sequence:
GGGGCAGGAATGCGCGGCGGGCGGCGCAGGAGGCGAGCGGTGGAACATGTAAGGGCACATCCCGCCAGCAGCCGCCCAGCTCGCAGACGGAGCGCAGGGGAGCGGGCGTGCGGGCGGCGAGGCGCAGG
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RefSeq Acc Id:
NP_038778 ⟸ NM_013750
- UniProtKB:
Q9WV95 (UniProtKB/Swiss-Prot)
- Sequence:
MTAAATVLKEGVLEKRSGGLLQLWKRKRCVLTERGLQLFEAKGTGGRPKELSFARIKAVECVESTGRHIYFTLVTEGGGEIDFRCPLEDPGWNAQITLGLVKFKNQQAIQTVRARQSLGTGTLVS
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Ensembl Acc Id:
ENSMUSP00000040614 ⟸ ENSMUST00000038945
RGD ID: 6875076 Promoter ID: EPDNEW_M989 Type: initiation region Name: Phlda3_1 Description: Mus musculus pleckstrin homology like domain, family A, member3 , mRNA. SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Mouse Assembly Chr Position (strand) Source GRCm38 1 135,766,162 - 135,766,222 EPDNEW
RGD ID: 6818234 Promoter ID: MM_KWN:2215 Type: CpG-Island SO ACC ID: SO:0000170 Source: MPROMDB Tissues & Cell Lines: 3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, Brain, ES_Cell, Lung, MEF_B4, MEF_B6 Transcripts: OTTMUST00000052474, OTTMUST00000052475 Position: Mouse Assembly Chr Position (strand) Source MGSCv36 1 137,662,026 - 137,663,612 (+) MPROMDB
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2016-02-29
Phlda3
pleckstrin homology like domain, family A, member 3
pleckstrin homology-like domain, family A, member 3
Symbol and/or name change
5135510 APPROVED
