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antiemetic +   
diphenhydramine +     
organic salt +     
(S)-(-)-sulpiride 
(S)-carbinoxamine maleate 
1-(2-oxo-2-phenylethyl)tetrahydrothiophenium 4-oxo-1-adamantyloxycarbonyldifluoromethanesulfonate 
1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[1-(3-hydroxyphenyl)ethylideneamino]-5-thiophen-2-yl-4-triazolecarboxamide 
6alpha-methylprednisolone +   
acetate salt +   
acetylide +  
acrivastine  
Akynzeo 
alcaftadine 
alcuronium bromide 
alosetron +  
alosetron hydrochloride 
antazoline  
aprepitant  
aripiprazole  
aripiprazole lauroxil 
Arsenobetaine 
aspartate salt +  
astemizole  
azatadine +   
azatadine maleate 
azelastine +   
azelastine hydrochloride 
benethamine salt +  
benzathine(2+) salt +  
benzoate salt +  
benzquinamide +  
benzylpenicillin clemizole 
bepotastine 
bepotastine besylate 
bile acid salt +   
bromazine +  
bromazine hydrochloride +  
brompheniramine +   
buclizine  
buclizine dihydrochloride 
carbinoxamine +   
carbinoxamine maleate +  
carphenazine +  
cetirizine  
chlorphenamine +   
chlorpromazine +   
chlorprothixene +   
cinnarizine  
citrate salt +   
clemastine +   
clemastine fumarate 
clemizole(1+) salt +  
clopenthixol +   
cyclizine +  
cyclizine hydrochloride 
cyproheptadine +   
cyproheptadine hydrochloride sesquihydrate 
deptropine +   
deptropine citrate 
desipramine +   
desloratadine  
dexamethasone +   
dexbrompheniramine +   
dexbrompheniramine maleate 
diclofenac epolamine 
dimenhydrinate  
The diphenhydramine salt of 8-chlorotheophylline. Its effects are similar to those of diphenhydramine, but it is less potent. It was thought that by combining the antiemetic effects of diphenhydramine with the mild stimulant effects of 8-chlorotheophyline, the extreme drowsiness induced by the former would be mitigated. However, the sedation caused by diphenhydramine is considerably stronger than the stimulation caused by 8-chlorotheophylline. Dimenhydrinate is used mainly as an antiemetic in the prevention and treatment of motion sickness.
diphenhydramine +   
diphenhydramine hydrochloride 
diphenhydramine salicylate 
diphenidol  
diphenylpyraline +   
diphenylpyraline hydrochloride 
dithiocarbamate salt +   
domperidone +   
domperidone maleate 
doxylamine  
droperidol  
emedastine +   
emedastine difumarate 
epinastine +   
fabesetron 
fexofenadine 
fingolimod hydrochloride  
fosaprepitant 
fosaprepitant dimeglumine 
fumarate salt +   
granisetron  
guanidine acetate 
guanidinium salt +  
haloperidol  
hydrabamine salt +  
hydroxyzine +   
iminium salt +  
ketotifen  
ketotifen fumarate 
lactate salt +  
malate salt +  
maleate salt +   
mepyramine  
methapyrilene +   
methapyrilene hydrochloride 
metoclopramide  
metoclopramide dihydrochloride monohydrate 
metoclopramide hydrochloride +  
mianserin +   
mirtazapine  
N-acetylglycinate salt +   
N-demethylmirtazapine 
netupitant +  
olanzapine  
organic ammonium salt +  
organic calcium salt +   
organic halide salt +   
organic hydrogensulfate salt +   
organic lithium salt +   
organic potassium salt +   
organic sodium salt +   
organic sulfate salt +   
organic tetrachlorozincate salt +  
organic tetrafluoroborate salt +  
organosulfonate salt +   
orphenadrine +   
orphenadrine citrate 
orphenadrine hydrochloride 
oxalate salt +  
pacatal 
pachypodol 
paliperidone 
paliperidone palmitate  
palonosetron  
palonosetron hydrochloride +  
penicillinate salt +  
perphenazine +   
pimozide  
potassium hydrogencarbonate 
procaine(1+) salt +  
prochlorperazine +   
promazine +   
promethazine  
promethazine hydrochloride 
propofol +   
pyridinium salt +   
pyrylium salt 
quinclorac-dimethylammonium 
risperidone  
rolapitant 
rolapitant hydrochloride (anhydrous) +  
rolapitant hydrochloride hydrate 
scopolamine +   
scopolamine hydrobromide trihydrate 
scopolamine methobromide 
sertindole  
squarates +  
succinate salt +  
sulpiride +   
tartrate salt +   
thalidomide +   
thiethylperazine +   
thionine acetate 
thioridazine +   
trazodone +   
trazodone hydrochloride 
trifluoperazine +   
triflupromazine +   
trimethobenzamide  
triphenylacetate salt +  
triphenylsulfonium 4-hydroxy-1-adamantyloxycarbonyldifluoromethanesulfonate 
triphenylsulfonium 4-oxo-1-adamantyloxycarbonyldifluoromethanesulfonate 
triprolidine  
triprolidine hydrochloride (anh.) +  
triprolidine hydrochloride monohydrate 
triprolidine(1+) +  
tropisetron  
tropisetron hydrochloride 
urate salt 
zingerone  
zuclopenthixol 

Synonyms
Exact Synonyms: 2-(diphenylmethoxy)-N,N-dimethylethanaminium 8-chloro-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurin-7-ide
Related Synonyms: (O-benzhydryl(dimethylamino)ethanol) 8-chlorotheophyllinate ;   8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1) ;   Benzhydryl-beta-dimethylaminoethylether 8-chlorotheophylline ;   Formula=C24H28ClN5O3 ;   InChI=1S/C17H21NO.C7H7ClN4O2/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14/h3-12,17H,13-14H2,1-2H3;1-2H3,(H,9,10,13) ;   InChIKey=DKHVTDUUNTVKOW-UHFFFAOYSA-N ;   N,N-dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinate ;   O-benzhydryldimethylaminoethanol 8-chlorotheophyllinate ;   SMILES=Cn1c2nc(Cl)[n-]c2c(=O)n(C)c1=O.C[NH+](C)CCOC(c1ccccc1)c1ccccc1 ;   beta-dimethylaminoethyl benzhydryl ether 1,3-dimethyl-8-chloroxanthine ;   dimenhidrinato ;   dimenhydrinatum ;   diphenhydramine 8-chlorotheophyllinate ;   diphenhydramine 8-chlorotheophylline ;   diphenhydramine theoclate
Xrefs: CAS:523-87-5 "ChemIDplus" ;   DrugBank:DB00985 ;   KEGG:D00520
Xref Mesh: MESH:D004111
Xrefs: Patent:US2499058 ;   Patent:US2534813

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.