Hadhb (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner VCMap
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Hadhb (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta) Mus musculus
Analyze
Symbol: Hadhb
Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
RGD ID: 733673
MGI Page MGI
Description: Exhibits acetyl-CoA C-acyltransferase activity. Predicted to be involved in fatty acid beta-oxidation. Localizes to mitochondrion. Is expressed in heart; liver; and placenta. Human ortholog(s) of this gene implicated in mitochondrial metabolism disease and mitochondrial trifunctional protein deficiency. Orthologous to human HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta); PARTICIPATES IN carnitine palmitoyltransferase I deficiency pathway; ethylmalonic encephalopathy pathway; fatty acid beta degradation pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4930479F15Rik; hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta aubunit; hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit; Mtp; Mtpb; TP-beta; trifunctional enzyme subunit beta, mitochondrial
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm9108   Hadhb-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39530,360,251 - 30,389,591 (+)NCBIGRCm39mm39
GRCm39 Ensembl530,360,246 - 30,389,591 (+)Ensembl
GRCm38530,155,253 - 30,184,593 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl530,155,248 - 30,184,593 (+)EnsemblGRCm38mm10GRCm38
MGSCv37530,481,862 - 30,511,123 (+)NCBIGRCm37mm9NCBIm37
MGSCv36530,486,109 - 30,515,370 (+)NCBImm8
Celera527,672,860 - 27,702,121 (+)NCBICelera
Cytogenetic Map5B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,6-dinitrotoluene  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
acetamide  (ISO)
ammonium chloride  (ISO)
Aroclor 1254  (EXP)
aspartame  (EXP)
benzo[a]pyrene  (EXP,ISO)
bezafibrate  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP)
buspirone  (ISO)
cadmium atom  (EXP)
carbon nanotube  (EXP)
ciprofibrate  (ISO)
clofibrate  (EXP,ISO)
Clofop  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (EXP)
dehydroepiandrosterone  (ISO)
dexamethasone  (EXP)
dextran sulfate  (EXP)
dibutyl phthalate  (EXP)
dichloroacetic acid  (EXP)
dicrotophos  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
ethanol  (EXP)
farnesol  (ISO)
fenofibrate  (EXP,ISO)
finasteride  (ISO)
flutamide  (EXP)
folic acid  (EXP)
gentamycin  (ISO)
GW 7647  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (ISO)
methotrexate  (ISO)
microcystin-LR  (EXP)
monosodium L-glutamate  (EXP)
N-ethyl-N-nitrosourea  (EXP)
nefazodone  (ISO)
nimesulide  (ISO)
ochratoxin A  (ISO)
oleic acid  (ISO)
paracetamol  (ISO)
perfluorobutanesulfonic acid  (ISO)
perfluorobutyric acid  (ISO)
perfluorododecanoic acid  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorohexanoic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
perfluoroundecanoic acid  (ISO)
phenobarbital  (ISO)
phlorizin  (EXP)
picrotoxin  (ISO)
pirinixic acid  (EXP,ISO)
pravastatin  (EXP,ISO)
propiconazole  (EXP)
resveratrol  (EXP)
rotenone  (EXP,ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
Soman  (ISO)
sulforaphane  (EXP)
sulindac  (ISO)
tacrolimus hydrate  (EXP)
Tesaglitazar  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (EXP,ISO)
tributylstannane  (EXP)
trichloroethene  (ISO)
troglitazone  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11116090   PMID:11390422   PMID:12477932   PMID:12819125   PMID:12865426   PMID:12904583   PMID:14610273  
PMID:14681479   PMID:15240869   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16916647   PMID:17116638   PMID:18614015   PMID:18799693   PMID:21267068   PMID:21565611  
PMID:21677750   PMID:21873635   PMID:22496890   PMID:25816318   PMID:27166947   PMID:27694478   PMID:29111324   PMID:29459677   PMID:29669786   PMID:30457570   PMID:32325033   PMID:32513690  


Genomics

Comparative Map Data
Hadhb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39530,360,251 - 30,389,591 (+)NCBIGRCm39mm39
GRCm39 Ensembl530,360,246 - 30,389,591 (+)Ensembl
GRCm38530,155,253 - 30,184,593 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl530,155,248 - 30,184,593 (+)EnsemblGRCm38mm10GRCm38
MGSCv37530,481,862 - 30,511,123 (+)NCBIGRCm37mm9NCBIm37
MGSCv36530,486,109 - 30,515,370 (+)NCBImm8
Celera527,672,860 - 27,702,121 (+)NCBICelera
Cytogenetic Map5B1NCBI
HADHB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl226,243,170 - 26,290,465 (+)EnsemblGRCh38hg38GRCh38
GRCh38226,244,917 - 26,290,465 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37226,467,807 - 26,513,333 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36226,321,120 - 26,366,837 (+)NCBINCBI36hg18NCBI36
Build 34226,379,471 - 26,424,983NCBI
Celera226,307,847 - 26,353,565 (+)NCBI
Cytogenetic Map2p23.3NCBI
HuRef226,213,206 - 26,249,388 (+)NCBIHuRef
CHM1_1226,397,520 - 26,443,240 (+)NCBICHM1_1
Hadhb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2626,153,572 - 26,187,668 (-)NCBI
Rnor_6.0 Ensembl627,555,412 - 27,582,995 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0627,555,408 - 27,589,539 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0637,366,082 - 37,400,364 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4626,139,397 - 26,173,428 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1626,142,349 - 26,169,900 (-)NCBI
Celera625,630,447 - 25,664,546 (-)NCBICelera
Cytogenetic Map6q14NCBI
Hadhb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554698,233,980 - 8,274,450 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554698,233,980 - 8,272,149 (+)NCBIChiLan1.0ChiLan1.0
HADHB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A26,334,043 - 26,379,059 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A26,334,043 - 26,379,059 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A26,240,365 - 26,285,982 (+)NCBIMhudiblu_PPA_v0panPan3
HADHB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11720,355,778 - 20,399,869 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1720,251,473 - 20,294,727 (+)NCBI
ROS_Cfam_1.01720,678,487 - 20,721,816 (+)NCBI
UMICH_Zoey_3.11720,365,181 - 20,408,616 (+)NCBI
UNSW_CanFamBas_1.01720,376,149 - 20,419,589 (+)NCBI
UU_Cfam_GSD_1.01720,422,834 - 20,465,929 (+)NCBI
Hadhb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_ltri_2NW_02440629264,656,832 - 64,699,845 (+)NCBI
SpeTri2.0NW_0049364936,139,717 - 6,182,792 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HADHB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3112,704,023 - 112,753,086 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13112,712,894 - 112,753,121 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23119,651,210 - 119,676,200 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HADHB
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11481,361,735 - 81,411,588 (-)NCBI
ChlSab1.1 Ensembl1481,361,612 - 81,411,432 (-)Ensembl
Hadhb
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247388,384,789 - 8,420,994 (+)NCBI

Position Markers
D9Mit34.1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map2C1.3UniSTS
Cytogenetic Map19D1UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11B4UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map1C1.3UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map2E2UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map1E3UniSTS
Cytogenetic Map5E1UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map16B3UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map19D3UniSTS
Cytogenetic Map1H5UniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map9DUniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map17DUniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map13A1UniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map12A3UniSTS
Cytogenetic Map1H2.1UniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map6A2UniSTS
Cytogenetic Map7B1UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map5C3.1UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map11B1.1UniSTS
Cytogenetic Map1H6UniSTS
Cytogenetic Map2C2UniSTS
Cytogenetic Map19CUniSTS
Cytogenetic Map17E1.3UniSTS
Cytogenetic Map5A1UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map13A5UniSTS
Cytogenetic MapXA1.1UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map3A3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map8CUniSTS
Cytogenetic Map12EUniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map1H1UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map1A2UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXC-DUniSTS
Cytogenetic Map5G1.3UniSTS
Cytogenetic Map7D1-E2UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map1H2.2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map16C1.1UniSTS
Cytogenetic Map15F2UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map1H4-H6UniSTS
Cytogenetic Map12D2UniSTS
Cytogenetic Map1G3UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map1H3UniSTS
Cytogenetic Map19BUniSTS
cM Map950.0UniSTS
Whitehead Genetic943.7UniSTS
Hadhb  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5B1UniSTS
cM Map516.04UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401122Pgia41_mproteoglycan induced arthritis 41 (mouse)Not determined561814634618282Mouse
15039371Nmrs21_mNAFLD-associated magnetic resonance shift 21 (mouse)5329982537299825Mouse
1301806Actd2_mactivity-distance traveled 2 (mouse)Not determined5517952239179654Mouse
4141207Imrfq1_mimmune response to Factor IX QTL 1 (mouse)Not determined5791911941919241Mouse
7394748Mom5_mmodifier of Min 5 (mouse)Not determined5879767233318293Mouse
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5884069387693978Mouse
1357478Kdnw1_mkidney weight 1 (mouse)Not determined5886594940372526Mouse
14696730Kidlq1_mkidney weight, left QTL 1 (mouse)51340580847405808Mouse
1301685Estq2_mestradiol regulated response QTL 2 (mouse)Not determined51547674049476846Mouse
1300719Iba5_minduction of brown adipocytes 5 (mouse)Not determined52052964954529790Mouse
1301776Skts3_mskin tumor susceptibility 3 (mouse)Not determined52150995255510060Mouse
11537368Hmtb10_mhemostasis and thrombosis 10 (mouse)52189582554342976Mouse
11537367Hmtb11_mhemostasis and thrombosis 11 (mouse)52189582564649236Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526236236138457140Mouse
1300701Cd8ts1_mCD8 T cell subset 1 (mouse)Not determined52705800661058109Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:871
Count of miRNA genes:426
Interacting mature miRNAs:479
Transcripts:ENSMUST00000026841, ENSMUST00000114783, ENSMUST00000114786, ENSMUST00000122934, ENSMUST00000123980, ENSMUST00000127364, ENSMUST00000133414, ENSMUST00000141236
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001289798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001289799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_145558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017320829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036165013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC158757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE945269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY337615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY778233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000026841   ⟹   ENSMUSP00000026841
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl530,155,248 - 30,184,593 (+)Ensembl
RefSeq Acc Id: ENSMUST00000114783   ⟹   ENSMUSP00000110431
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl530,155,272 - 30,184,582 (+)Ensembl
RefSeq Acc Id: ENSMUST00000114786   ⟹   ENSMUSP00000110434
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl530,155,272 - 30,184,589 (+)Ensembl
RefSeq Acc Id: ENSMUST00000122934
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl530,174,958 - 30,179,094 (+)Ensembl
RefSeq Acc Id: ENSMUST00000123980   ⟹   ENSMUSP00000118296
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl530,155,258 - 30,174,953 (+)Ensembl
RefSeq Acc Id: ENSMUST00000127364
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl530,155,275 - 30,168,273 (+)Ensembl
RefSeq Acc Id: ENSMUST00000133414
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl530,178,561 - 30,180,975 (+)Ensembl
RefSeq Acc Id: ENSMUST00000141236
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl530,180,232 - 30,184,236 (+)Ensembl
RefSeq Acc Id: ENSMUST00000197109   ⟹   ENSMUSP00000142868
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl530,155,303 - 30,176,891 (+)Ensembl
RefSeq Acc Id: NM_001289798   ⟹   NP_001276727
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39530,360,251 - 30,389,591 (+)NCBI
GRCm38530,155,253 - 30,184,593 (+)NCBI
Celera527,672,791 - 27,702,131 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001289799   ⟹   NP_001276728
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39530,360,251 - 30,389,591 (+)NCBI
GRCm38530,155,253 - 30,184,593 (+)NCBI
Celera527,672,791 - 27,702,131 (+)NCBI
Sequence:
RefSeq Acc Id: NM_145558   ⟹   NP_663533
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39530,360,251 - 30,389,591 (+)NCBI
GRCm38530,155,253 - 30,184,593 (+)NCBI
MGSCv37530,481,862 - 30,511,123 (+)RGD
Celera527,672,791 - 27,702,131 (+)NCBI
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017320829   ⟹   XP_017176318
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39530,361,200 - 30,389,586 (+)NCBI
GRCm38530,155,596 - 30,184,588 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036165013   ⟹   XP_036020906
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39530,361,200 - 30,389,586 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_663533   ⟸   NM_145558
- Peptide Label: precursor
- UniProtKB: Q99JY0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001276727   ⟸   NM_001289798
- Peptide Label: precursor
- UniProtKB: Q99JY0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001276728   ⟸   NM_001289799
- Peptide Label: precursor
- UniProtKB: Q99JY0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017176318   ⟸   XM_017320829
- Peptide Label: isoform X1
- UniProtKB: Q99JY0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000142868   ⟸   ENSMUST00000197109
RefSeq Acc Id: ENSMUSP00000026841   ⟸   ENSMUST00000026841
RefSeq Acc Id: ENSMUSP00000110434   ⟸   ENSMUST00000114786
RefSeq Acc Id: ENSMUSP00000110431   ⟸   ENSMUST00000114783
RefSeq Acc Id: ENSMUSP00000118296   ⟸   ENSMUST00000123980
RefSeq Acc Id: XP_036020906   ⟸   XM_036165013
- Peptide Label: isoform X1
Protein Domains
Thiolase_N

Promoters
RGD ID:6886278
Promoter ID:EPDNEW_M6590
Type:initiation region
Name:Hadhb_1
Description:Mus musculus hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-CoenzymeA thiolase/enoyl-Coenzyme A hydratase , beta subunit , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38530,155,292 - 30,155,352EPDNEW
RGD ID:6837694
Promoter ID:MM_KWN:41746
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000114783,   ENSMUST00000114786,   OTTMUST00000060908,   OTTMUST00000060911,   OTTMUST00000060920,   OTTMUST00000061037,   OTTMUST00000061038,   UC008WVD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36530,481,411 - 30,481,917 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2136381 AgrOrtholog
Ensembl Genes ENSMUSG00000059447 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000026841 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000110431 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000110434 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000118296 UniProtKB/TrEMBL
  ENSMUSP00000142868 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000026841 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000114783 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000114786 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000123980 UniProtKB/TrEMBL
  ENSMUST00000197109 UniProtKB/TrEMBL
Gene3D-CATH 3.40.47.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Thiolase UniProtKB/Swiss-Prot
  Thiolase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thiolase_acyl_enz_int_AS UniProtKB/Swiss-Prot
  Thiolase_AS UniProtKB/Swiss-Prot
  Thiolase_C UniProtKB/Swiss-Prot
  Thiolase_CS UniProtKB/Swiss-Prot
  Thiolase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:231086 UniProtKB/Swiss-Prot
MGD MGI:2136381 ENTREZGENE
NCBI Gene 231086 ENTREZGENE
Pfam Thiolase_C UniProtKB/Swiss-Prot
  Thiolase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hadhb PhenoGen
PROSITE THIOLASE_1 UniProtKB/Swiss-Prot
  THIOLASE_2 UniProtKB/Swiss-Prot
  THIOLASE_3 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53901 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs AcCoA-C-Actrans UniProtKB/Swiss-Prot
UniProt A0A0G2JER1_MOUSE UniProtKB/TrEMBL
  D3YXU1_MOUSE UniProtKB/TrEMBL
  ECHB_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q3TEH9 UniProtKB/Swiss-Prot
  Q8BJI5 UniProtKB/Swiss-Prot
  Q8BJM0 UniProtKB/Swiss-Prot
  Q8BK52 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-10-16 Hadhb  hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta  Hadhb  hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit  Symbol and/or name change 5135510 APPROVED