Cdc42 (cell division cycle 42) - Rat Genome Database
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Gene: Cdc42 (cell division cycle 42) Mus musculus
Analyze
Symbol: Cdc42
Name: cell division cycle 42
RGD ID: 730977
MGI Page MGI
Description: Exhibits several functions, including GTP-dependent protein binding activity; GTPase activity; and Rho GDP-dissociation inhibitor binding activity. Involved in several processes, including neuron differentiation; positive regulation of cellular component organization; and positive regulation of phosphorylation. Localizes to several cellular components, including leading edge membrane; phagocytic vesicle; and storage vacuole. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and hemolymphoid system gland. Used to study microvillus inclusion disease. Human ortholog(s) of this gene implicated in fibrosarcoma. Orthologous to human CDC42 (cell division cycle 42); PARTICIPATES IN adenosine signaling pathway; c-Jun N-terminal kinases MAPK signaling pathway; E-cadherin signaling pathway; INTERACTS WITH (S)-nicotine; 1,2-dimethylhydrazine; 1,4-dichlorobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI747189; AU018915; cell division control protein 42 homolog; cell division cycle 42 homolog; G25K GTP-binding protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm12492   Gm18964   Gm7407  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394137,047,007 - 137,085,070 (-)NCBIGRCm39mm39
GRCm384137,319,696 - 137,357,759 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4137,319,696 - 137,357,720 (-)EnsemblGRCm38mm10GRCm38
MGSCv374136,875,611 - 136,913,652 (-)NCBIGRCm37mm9NCBIm37
MGSCv364136,591,779 - 136,608,205 (-)NCBImm8
Celera4135,540,002 - 135,577,854 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map469.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (EXP)
1,2-dimethylhydrazine  (EXP)
1,4-dichlorobenzene  (EXP)
1,8-cineole  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
17alpha-ethynylestradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4-dinitrotoluene  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4-hydroxyphenyl retinamide  (EXP)
acetylsalicylic acid  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
bazedoxifene  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bortezomib  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
calcium atom  (EXP)
calcium(0)  (EXP)
carbon nanotube  (ISO)
carboplatin  (ISO)
casticin  (EXP)
cefaloridine  (ISO)
chrysene  (EXP)
cisplatin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
crocidolite asbestos  (EXP)
CU-O LINKAGE  (ISO)
D-glucose  (EXP)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
disodium selenite  (ISO)
ethanol  (EXP,ISO)
flusilazole  (EXP)
folic acid  (EXP)
formaldehyde  (ISO)
fumonisin B1  (EXP)
gallic acid  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gentamycin  (ISO)
glucose  (EXP)
glyphosate  (ISO)
GTP  (EXP,ISO)
haloperidol  (ISO)
hexaconazole  (EXP)
hydralazine  (ISO)
hypochlorous acid  (EXP)
indometacin  (ISO)
kainic acid  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
lovastatin  (EXP,ISO)
mercury dichloride  (ISO)
metformin  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
microcystin-LR  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
niclosamide  (ISO)
nicotine  (EXP)
NSC 23766  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (EXP)
phenobarbital  (EXP)
pioglitazone  (ISO)
piroxicam  (ISO)
Propiverine  (ISO)
quercetin  (ISO)
resveratrol  (EXP,ISO)
Risedronate sodium  (EXP,ISO)
rotenone  (ISO)
SB 431542  (ISO)
simvastatin  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
tamoxifen  (EXP)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
titanium dioxide  (EXP)
tremolite asbestos  (ISO)
triadimefon  (EXP)
Triptolide  (ISO)
valproic acid  (ISO)
warfarin  (EXP)
zinc oxide  (ISO)
zoledronic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton organization  (ISO)
actin filament branching  (ISO)
actin filament organization  (ISO)
adherens junction organization  (IMP)
cardiac conduction system development  (IGI)
Cdc42 protein signal transduction  (IBA,ISO)
cell differentiation  (IEA)
cell junction assembly  (ISO)
cell migration  (IBA)
cell projection assembly  (IBA)
cell-cell adhesion  (TAS)
cellular protein localization  (IMP)
cellular response to interferon-gamma  (IDA)
dendritic cell migration  (IGI)
dendritic spine morphogenesis  (IMP)
endocytosis  (IBA,IMP)
endosomal transport  (TAS)
establishment of epithelial cell apical/basal polarity  (ISO)
establishment of Golgi localization  (ISO)
establishment or maintenance of apical/basal cell polarity  (IMP)
establishment or maintenance of cell polarity  (TAS)
filopodium assembly  (IDA)
Golgi organization  (ISO)
heart contraction  (IGI)
integrin-mediated signaling pathway  (ISO)
modification of synaptic structure  (IBA,ISO)
negative regulation of protein-containing complex assembly  (ISO)
nervous system development  (IEA)
neuron fate determination  (IMP)
neuropilin signaling pathway  (ISO)
nuclear migration  (IMP)
nucleus localization  (IMP)
organelle transport along microtubule  (ISO)
phagocytosis, engulfment  (ISO)
positive regulation of actin cytoskeleton reorganization  (ISO)
positive regulation of catalytic activity  (ISO)
positive regulation of cell growth  (ISO)
positive regulation of cytokinesis  (ISO)
positive regulation of DNA replication  (ISO)
positive regulation of epithelial cell proliferation involved in lung morphogenesis  (IMP)
positive regulation of filopodium assembly  (IMP,ISO)
positive regulation of intracellular protein transport  (ISO)
positive regulation of JNK cascade  (ISO)
positive regulation of lamellipodium assembly  (ISO)
positive regulation of MAPK cascade  (IDA)
positive regulation of neuron apoptotic process  (ISO)
positive regulation of phosphatidylinositol 3-kinase activity  (IMP)
positive regulation of pinocytosis  (IMP)
positive regulation of pseudopodium assembly  (ISO)
positive regulation of stress fiber assembly  (ISO)
positive regulation of substrate adhesion-dependent cell spreading  (ISO)
positive regulation of synapse structural plasticity  (ISO)
regulation of attachment of spindle microtubules to kinetochore  (ISO)
regulation of filopodium assembly  (ISO)
regulation of lamellipodium assembly  (ISO)
regulation of mitotic nuclear division  (IMP)
regulation of modification of postsynaptic structure  (ISO)
regulation of protein binding  (IDA)
regulation of stress fiber assembly  (ISO)
Rho protein signal transduction  (TAS)
small GTPase mediated signal transduction  (IEA)
sprouting angiogenesis  (ISO)
submandibular salivary gland formation  (ISO)
substantia nigra development  (ISO)
viral RNA genome replication  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal anus morphology  (IAGP)
abnormal autopod joint morphology  (IAGP)
abnormal autopod morphology  (IAGP)
abnormal brain ependyma morphology  (IAGP)
abnormal brain ventricle morphology  (IAGP)
abnormal cartilage development  (IAGP)
abnormal cell morphology  (IAGP)
abnormal cell nucleus morphology  (IAGP)
abnormal cellular glucose uptake  (IAGP)
abnormal cerebral aqueduct morphology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal cortical plate morphology  (IAGP)
abnormal cortical ventricular zone morphology  (IAGP)
abnormal cranium morphology  (IEA)
abnormal crypts of Lieberkuhn morphology  (IAGP)
abnormal defecation  (IAGP)
abnormal embryonic neuroepithelium morphology  (IAGP)
abnormal enterocyte morphology  (IAGP)
abnormal epidermal layer morphology  (IAGP)
abnormal epidermis stratum corneum morphology  (IAGP)
abnormal eye development  (IAGP)
abnormal folding of telencephalic vesicles  (IAGP)
abnormal glial cell morphology  (IAGP)
abnormal hair follicle matrix region morphology  (IAGP)
abnormal hair follicle morphology  (IAGP)
abnormal hair shaft morphology  (IAGP)
abnormal interdigital cell death  (IAGP)
abnormal intestinal enteroendocrine cell morphology  (IAGP)
abnormal intestinal epithelium morphology  (IAGP)
abnormal intestinal goblet cell morphology  (IAGP)
abnormal intestine morphology  (IAGP)
abnormal intestine physiology  (IAGP)
abnormal intramembranous bone ossification  (IAGP)
abnormal joint morphology  (IAGP)
abnormal keratinocyte morphology  (IAGP)
abnormal kidney cortex morphology  (IAGP)
abnormal kidney development  (IAGP)
abnormal kidney papilla morphology  (IAGP)
abnormal lateral ventricle morphology  (IAGP)
abnormal limb bone morphology  (IAGP)
abnormal limb morphology  (IAGP)
abnormal long bone epiphyseal plate morphology  (IAGP)
abnormal myelin sheath morphology  (IAGP)
abnormal neocortex morphology  (IAGP)
abnormal nephrogenic zone morphology  (IAGP)
abnormal neuronal precursor proliferation  (IAGP)
abnormal Paneth cell morphology  (IAGP)
abnormal parietal lobe morphology  (IAGP)
abnormal platelet activation  (IAGP)
abnormal platelet dense granule physiology  (IAGP)
abnormal platelet morphology  (IAGP)
abnormal platelet physiology  (IAGP)
abnormal proximal convoluted tubule morphology  (IAGP)
abnormal renal tubule epithelium morphology  (IAGP)
abnormal retina morphology  (IEA)
abnormal secondary palate development  (IAGP)
abnormal small intestinal crypt cell physiology  (IAGP)
abnormal small intestinal villus morphology  (IAGP)
abnormal spinal cord central canal morphology  (IAGP)
abnormal suckling behavior  (IAGP)
abnormal telencephalon development  (IAGP)
abnormal third ventricle morphology  (IAGP)
abnormal xiphoid process morphology  (IAGP)
absent brain ependyma motile cilia  (IAGP)
absent embryonic epiblast  (IAGP)
absent gastric milk in neonates  (IAGP)
absent hair follicle inner root sheath  (IAGP)
absent Paneth cells  (IAGP)
anuria  (IAGP)
brachydactyly  (IAGP)
cerebral aqueductal stenosis  (IAGP)
cleft palate  (IAGP)
decreased birth body size  (IAGP)
decreased body length  (IAGP)
decreased body size  (IAGP)
decreased cardiac output  (IAGP)
decreased cardiac stroke volume  (IAGP)
decreased circulating serum albumin level  (IEA)
decreased embryo size  (IAGP)
decreased neuronal precursor cell number  (IAGP)
decreased Paneth cell number  (IAGP)
decreased renal glomerulus number  (IAGP)
decreased renal tubule number  (IAGP)
decreased ventricle muscle contractility  (IAGP)
delayed fontanelle closure  (IAGP)
dermal cysts  (IAGP)
disorganized embryonic tissue  (IAGP)
disorganized long bone epiphyseal plate  (IAGP)
domed cranium  (IAGP)
embryonic lethality between implantation and somite formation, complete penetrance  (IAGP)
embryonic lethality prior to organogenesis  (IEA)
embryonic lethality prior to tooth bud stage  (IEA)
enlarged brain ventricles  (IAGP)
enlarged kidney  (IEA)
enlarged lateral ventricles  (IAGP)
enlarged third ventricle  (IAGP)
epidermal hyperplasia  (IAGP)
fused metacarpal bones  (IAGP)
fused phalanges  (IAGP)
holoprosencephaly  (IAGP)
hydrocephaly  (IAGP)
hyperkeratosis  (IAGP)
hypoactivity  (IAGP)
increased bleeding time  (IAGP)
increased circulating alkaline phosphatase level  (IEA)
increased circulating aspartate transaminase level  (IEA)
increased lean body mass  (IEA)
increased platelet aggregation  (IAGP)
increased small intestinal crypt cell apoptosis  (IAGP)
increased susceptibility to induced thrombosis  (IAGP)
increased susceptibility to kidney reperfusion injury  (IAGP)
increased width of hypertrophic chondrocyte zone  (IAGP)
interdigital webbing  (IAGP)
intestinal edema  (IAGP)
intraventricular hemorrhage  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
preweaning lethality, complete penetrance  (IEA)
prolonged P wave  (IAGP)
prolonged QRS complex duration  (IAGP)
prolonged QT interval  (IAGP)
renal hypoplasia  (IAGP)
respiratory distress  (IAGP)
short limbs  (IAGP)
short tibia  (IEA)
small embryonic telencephalon  (IAGP)
small olfactory bulb  (IAGP)
split sternum  (IAGP)
syndactyly  (IAGP)
thin cerebral cortex  (IAGP)
thrombocytopenia  (IAGP)
weakness  (IAGP)
References

References - curated
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12. MGD and Homologene mouse data transfer
13. MGD data from the GO Consortium
14. MGD IEA
15. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
16. OMIM Disease Annotation Pipeline
17. Padmos RC, etal., Arch Gen Psychiatry. 2008 Apr;65(4):395-407.
18. Pipeline to import KEGG annotations from KEGG into RGD
19. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
20. Pipeline to import SMPDB annotations from SMPDB into RGD
21. RGD automated import pipeline
22. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
23. RGD automated import pipeline for gene-chemical interactions
24. Sharma AK, etal., Toxicol Pathol. 2009 Oct;37(6):776-89. Epub 2009 Aug 21.
25. Teramoto H, etal., J Biol Chem. 1996 Nov 1;271(44):27225-8.
26. Wang Z and Thurmond DC, J Cell Sci. 2009 Apr 1;122(Pt 7):893-903.
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28. Yang D, etal., Dig Dis Sci. 2017 Apr;62(4):958-967. doi: 10.1007/s10620-017-4451-z. Epub 2017 Feb 8.
29. Zhao J, etal., Cell Signal. 2007 Apr;19(4):831-43. Epub 2006 Dec 8.
30. Zhu X, etal., Int J Dev Neurosci. 2000 Jul-Aug;18(4-5):433-7.
Additional References at PubMed
PMID:886261   PMID:1555775   PMID:2124704   PMID:7888179   PMID:8288233   PMID:8464478   PMID:8817303   PMID:8889548   PMID:9438836   PMID:9535835   PMID:9606207   PMID:9828140  
PMID:9917367   PMID:10349636   PMID:10490598   PMID:10493740   PMID:10495887   PMID:10699171   PMID:10898977   PMID:10922068   PMID:10934474   PMID:10954424   PMID:11035016   PMID:11042159  
PMID:11048641   PMID:11076861   PMID:11130076   PMID:11238453   PMID:11307167   PMID:11431694   PMID:11544199   PMID:11562357   PMID:11672528   PMID:11673526   PMID:12006490   PMID:12034499  
PMID:12107726   PMID:12112462   PMID:12123608   PMID:12165471   PMID:12213441   PMID:12213839   PMID:12376551   PMID:12384416   PMID:12477932   PMID:12482591   PMID:12520002   PMID:12531901  
PMID:12538863   PMID:12547822   PMID:12566226   PMID:12566459   PMID:12598535   PMID:12609829   PMID:12637522   PMID:12676083   PMID:12760905   PMID:12773384   PMID:12842876   PMID:12904583  
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PMID:17265067   PMID:17267693   PMID:17289663   PMID:17360364   PMID:17409253   PMID:17468766   PMID:17500055   PMID:17524389   PMID:17573353   PMID:17576798   PMID:17579061   PMID:17634366  
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PMID:18799693   PMID:18824165   PMID:18829452   PMID:18838382   PMID:18854161   PMID:19001503   PMID:19015276   PMID:19085966   PMID:19097998   PMID:19100259   PMID:19126596   PMID:19144319  
PMID:19190242   PMID:19208628   PMID:19244314   PMID:19265663   PMID:19273601   PMID:19286565   PMID:19289122   PMID:19349584   PMID:19363157   PMID:19404406   PMID:19443691   PMID:19463088  
PMID:19463158   PMID:19640983   PMID:19671682   PMID:19671922   PMID:19693013   PMID:19696411   PMID:19741094   PMID:19741299   PMID:19752396   PMID:19796622   PMID:19808890   PMID:19820184  
PMID:19893577   PMID:19914171   PMID:19955216   PMID:20028975   PMID:20067919   PMID:20139097   PMID:20345913   PMID:20501942   PMID:20547841   PMID:20551175   PMID:20595387   PMID:20637038  
PMID:20719958   PMID:20871610   PMID:20937872   PMID:21048135   PMID:21048939   PMID:21059854   PMID:21062867   PMID:21115489   PMID:21122105   PMID:21177343   PMID:21267068   PMID:21339294  
PMID:21344485   PMID:21382550   PMID:21397010   PMID:21421844   PMID:21455314   PMID:21502507   PMID:21533980   PMID:21618100   PMID:21645877   PMID:21659643   PMID:21685891   PMID:21690310  
PMID:21789221   PMID:21828338   PMID:21844200   PMID:21873635   PMID:21880728   PMID:21880909   PMID:21880919   PMID:21966369   PMID:22023353   PMID:22128240   PMID:22228100   PMID:22340378  
PMID:22354172   PMID:22387309   PMID:22454526   PMID:22456512   PMID:22461490   PMID:22461561   PMID:22494997   PMID:22518006   PMID:22560076   PMID:22596063   PMID:22683270   PMID:22732842  
PMID:22810622   PMID:22932798   PMID:22958929   PMID:22966049   PMID:22989773   PMID:23022564   PMID:23139861   PMID:23150167   PMID:23171661   PMID:23209325   PMID:23219958   PMID:23248743  
PMID:23264738   PMID:23284167   PMID:23295348   PMID:23325254   PMID:23358418   PMID:23372671   PMID:23384564   PMID:23392682   PMID:23446420   PMID:23524265   PMID:23542688   PMID:23555292  
PMID:23608596   PMID:23620790   PMID:23665500   PMID:23677246   PMID:23690402   PMID:23706742   PMID:23766535   PMID:23793062   PMID:23861058   PMID:23861250   PMID:23872330   PMID:23979594  
PMID:24003235   PMID:24014231   PMID:24056078   PMID:24059268   PMID:24076653   PMID:24100016   PMID:24131996   PMID:24178298   PMID:24244167   PMID:24276241   PMID:24428713   PMID:24449844  
PMID:24610943   PMID:24788519   PMID:24792215   PMID:24952961   PMID:25006034   PMID:25057989   PMID:25073924   PMID:25113996   PMID:25190059   PMID:25211221   PMID:25217619   PMID:25288640  
PMID:25343271   PMID:25451153   PMID:25477463   PMID:25490006   PMID:25497016   PMID:25547673   PMID:25662318   PMID:25737280   PMID:25770185   PMID:25851601   PMID:25870239   PMID:25892012  
PMID:26002917   PMID:26051942   PMID:26092936   PMID:26204446   PMID:26253403   PMID:26416959   PMID:26490995   PMID:26553928   PMID:26558612   PMID:26566162   PMID:26728565   PMID:26733533  
PMID:26739452   PMID:26747246   PMID:26772200   PMID:26783302   PMID:26820532   PMID:26845352   PMID:26902112   PMID:26905694   PMID:26912661   PMID:26932803   PMID:26969129   PMID:27114066  
PMID:27134173   PMID:27143109   PMID:27225763   PMID:27486147   PMID:27566402   PMID:27600824   PMID:27635527   PMID:27680697   PMID:27917469   PMID:27986432   PMID:28028151   PMID:28028174  
PMID:28031329   PMID:28171747   PMID:28181299   PMID:28238662   PMID:28289096   PMID:28296078   PMID:28378742   PMID:28389565   PMID:28457749   PMID:28465335   PMID:28643773   PMID:28706196  
PMID:28747344   PMID:28754687   PMID:28778865   PMID:28871124   PMID:28973878   PMID:29145128   PMID:29253508   PMID:29296000   PMID:29314205   PMID:29330353   PMID:29377497   PMID:29422044  
PMID:29440353   PMID:29518331   PMID:29556338   PMID:29626467   PMID:29632244   PMID:29663842   PMID:29673588   PMID:29684584   PMID:29700112   PMID:29853619   PMID:29867343   PMID:29874522  
PMID:29976179   PMID:30042182   PMID:30189608   PMID:30227235   PMID:30254339   PMID:30307073   PMID:30333726   PMID:30387892   PMID:30540520   PMID:30562941   PMID:30590745   PMID:30732528  
PMID:30846568   PMID:30853186   PMID:30985297   PMID:31060803   PMID:31062617   PMID:31084928   PMID:31219639   PMID:31246175   PMID:31410202   PMID:31462248   PMID:31487690   PMID:31877301  
PMID:32290105   PMID:32325033   PMID:32581705   PMID:32819561   PMID:32866472  


Genomics

Comparative Map Data
Cdc42
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394137,047,007 - 137,085,070 (-)NCBIGRCm39mm39
GRCm384137,319,696 - 137,357,759 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4137,319,696 - 137,357,720 (-)EnsemblGRCm38mm10GRCm38
MGSCv374136,875,611 - 136,913,652 (-)NCBIGRCm37mm9NCBIm37
MGSCv364136,591,779 - 136,608,205 (-)NCBImm8
Celera4135,540,002 - 135,577,854 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map469.83NCBI
CDC42
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl122,025,511 - 22,101,360 (+)EnsemblGRCh38hg38GRCh38
GRCh38122,052,709 - 22,101,360 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37122,379,202 - 22,427,853 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh37122,379,120 - 22,419,439 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,251,707 - 22,292,023 (+)NCBINCBI36hg18NCBI36
Build 34122,124,487 - 22,164,741NCBI
Celera120,702,109 - 20,742,389 (+)NCBI
Cytogenetic Map1p36.12NCBI
HuRef120,622,960 - 20,663,212 (+)NCBIHuRef
CHM1_1122,491,651 - 22,531,931 (+)NCBICHM1_1
Cdc42
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25149,555,069 - 149,593,239 (-)NCBI
Rnor_6.0 Ensembl5155,691,390 - 155,728,300 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05155,690,267 - 155,728,385 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05159,446,154 - 159,485,163 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45156,106,123 - 156,143,040 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15156,116,164 - 156,153,079 (-)NCBI
Celera5147,953,334 - 147,989,998 (-)NCBICelera
Cytogenetic Map5q36NCBI
Cdc42
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554522,255,117 - 2,299,042 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554522,255,940 - 2,299,042 (+)NCBIChiLan1.0ChiLan1.0
CDC42
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1122,188,722 - 22,228,351 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0121,245,970 - 21,286,210 (+)NCBIMhudiblu_PPA_v0panPan3
LOC403934
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl277,153,095 - 77,199,211 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1277,153,276 - 77,169,947 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Cdc42
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364747,556,765 - 7,598,687 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC42
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl680,035,122 - 80,089,233 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1680,035,034 - 80,089,243 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2674,057,184 - 74,116,824 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDC42
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120110,568,004 - 110,608,318 (-)NCBI
ChlSab1.1 Ensembl20110,569,352 - 110,582,562 (-)Ensembl
Cdc42
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247646,874,453 - 6,891,952 (+)NCBI

Position Markers
BB377396  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384137,331,537 - 137,331,669UniSTSGRCm38
MGSCv374136,887,452 - 136,887,584UniSTSGRCm37
Celera4135,551,770 - 135,551,902UniSTS
Cytogenetic Map4D3UniSTS
cM Map466.75UniSTS
Whitehead/MRC_RH41802.48UniSTS
RH136515  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384137,319,801 - 137,320,006UniSTSGRCm38
GRCm38X146,710,947 - 146,711,151UniSTSGRCm38
MGSCv37X143,145,490 - 143,145,694UniSTSGRCm37
MGSCv374136,875,716 - 136,875,921UniSTSGRCm37
Celera4135,540,107 - 135,540,312UniSTS
CeleraX130,655,854 - 130,656,058UniSTS
Cytogenetic Map4D3UniSTS
cM Map466.75UniSTS
AI747189  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384137,319,945 - 137,320,024UniSTSGRCm38
GRCm38443,797,051 - 43,797,131UniSTSGRCm38
MGSCv374136,875,860 - 136,875,939UniSTSGRCm37
MGSCv37443,809,923 - 43,810,003UniSTSGRCm37
Celera4135,540,251 - 135,540,330UniSTS
Celera443,826,575 - 43,826,655UniSTS
Cytogenetic Map4D3UniSTS
cM Map466.75UniSTS
Whitehead/MRC_RH41797.84UniSTS
RH126279  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384137,353,926 - 137,354,175UniSTSGRCm38
MGSCv374136,909,841 - 136,910,090UniSTSGRCm37
Celera4135,573,826 - 135,574,075UniSTS
Cytogenetic Map4D3UniSTS
cM Map466.8UniSTS
Whitehead/MRC_RH41802.48UniSTS
Cdc42  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv374136,875,676 - 136,875,862UniSTSGRCm37
MGSCv374136,884,502 - 136,884,693UniSTSGRCm37
Celera4135,540,067 - 135,540,253UniSTS
Celera4135,548,828 - 135,549,019UniSTS
Cytogenetic Map4D3UniSTS
cM Map466.75UniSTS
cM Map466.75UniSTS
cM Map466.75UniSTS
UniSTS:224478  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384137,322,296 - 137,322,450UniSTSGRCm38
MGSCv374136,878,211 - 136,878,365UniSTSGRCm37
Celera4135,542,602 - 135,542,756UniSTS
Cytogenetic Map4D3UniSTS
cM Map466.75UniSTS
Cdc42  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384137,328,587 - 137,328,778UniSTSGRCm38
MGSCv374136,884,502 - 136,884,693UniSTSGRCm37
Celera4135,548,828 - 135,549,019UniSTS
Cytogenetic Map4D3UniSTS
cM Map466.75UniSTS
Cdc42  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384137,319,761 - 137,319,947UniSTSGRCm38
MGSCv374136,875,676 - 136,875,862UniSTSGRCm37
Celera4135,540,067 - 135,540,253UniSTS
Cytogenetic Map4D3UniSTS
cM Map466.75UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156183778Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138615442Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155600000Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465800000146500000Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468100000150800000Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined89063832140740892Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined89063832140740892Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined89063832140740892Mouse
1357529Lvrq8_mliver weight QTL 8 (mouse)Not determined489063832140740892Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)489063832140740892Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined489063832151570093Mouse
13208562Wght7_mweight 7 (mouse)491000000148000000Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined495069342150592401Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105812001139812001Mouse
15039378Adip30_madiposity 30 (mouse)4105812001139812001Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105812001139812001Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105978113141706527Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105978113141706527Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105978113141706527Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105978113141706527Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107161300141161387Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107371164141371360Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107371164141371360Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107371164141371360Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107897771141897963Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108583899142583899Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108583899142583899Mouse
10755521Hct1_mhematocrit 1 (mouse)4108583899142583899Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111115258145115487Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111115258145115487Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112288593146288593Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112629696146629696Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112930596146930596Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116427367150427471Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117673830151673964Mouse
14746982Manh56_mmandible shape 56 (mouse)4118088606152088606Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4120137122154137225Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4120137122154137225Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120890537154890684Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120890537154890684Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120946694154946840Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120946694154946840Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121615338155615442Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121615338155615442Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121615338155615442Mouse
27226757Femd1_mfemur midshaft diameter 1, 5 week (mouse)4124100000144600000Mouse
4141065Shali2_msurvival time to hyperoxic acute lung injury 2 (mouse)Not determined124161300141845481Mouse
1300917Gasa1_mgastritis type A susceptibility locus 1 (mouse)Not determined4124161300142711450Mouse
1302149Tlsr2_mthymic lymphoma suppressor region 2 (mouse)Not determined4124371164142504390Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124371164150592401Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124826172156508116Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124893970156508116Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124893970156508116Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124893970156508116Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125504302156508116Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125504302156508116Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125504302156508116Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125562755156508116Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4128057656156508116Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4128057656156508116Mouse
1301584Lrdg2_mlight induced retinal degeneration 2 (mouse)Not determined4129572018151570093Mouse
4141154Nba1_mNew Zealand Black autoimmunity 1 (mouse)Not determined131923413141151964Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4132926037156508116Mouse
4142082Psds2_mpsoriasis-like skin disease severity 2 (mouse)Not determined4133427367137890684Mouse
1301267Bcmd2_mB cell maturation defect 2 (mouse)Not determined4133427367150704994Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133592276156508116Mouse
1301108Scon2_msucrose consumption 2 (mouse)Not determined4134569994156508116Mouse
1300537Ap3q_malcohol preference 3 QTL (mouse)Not determined4134569994156508116Mouse
4141779Ssrq8_mstress response QTL 8 (mouse)Not determined137148689137890684Mouse
12050091Shm2_msperm head morphology 2 (mouse)4137148689138615442Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir133a-2mmu-miR-133a-3pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//Northern blFunctional MTI17468766
Mir330mmu-miR-330-5pOncomiRDBexternal_infoNANA23337504
Mir1a-1mmu-miR-1a-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI21690310
Mir1a-2mmu-miR-1a-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI21690310
Mir124a-2mmu-miR-124-3pMirtarbaseexternal_infoWestern blotFunctional MTI18619591
Mir137mmu-miR-137-5pOncomiRDBexternal_infoNANA23178712
Mir137mmu-miR-137-5pOncomiRDBexternal_infoNANA20473940

Predicted Target Of
Summary Value
Count of predictions:717
Count of miRNA genes:425
Interacting mature miRNAs:491
Transcripts:ENSMUST00000030417, ENSMUST00000051477
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001243769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK003098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL645468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC064792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE685696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF467211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD353254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD551112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L11318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L78075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M79301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U37720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U76960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000030417   ⟹   ENSMUSP00000030417
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl4137,321,762 - 137,357,699 (-)Ensembl
RefSeq Acc Id: ENSMUST00000051477   ⟹   ENSMUSP00000054634
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl4137,319,696 - 137,357,720 (-)Ensembl
RefSeq Acc Id: NM_001243769   ⟹   NP_001230698
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394137,049,073 - 137,085,070 (-)NCBI
GRCm384137,321,762 - 137,357,759 (-)NCBI
Celera4135,540,002 - 135,577,876 (-)ENTREZGENE
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_009861   ⟹   NP_033991
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394137,047,007 - 137,085,070 (-)NCBI
GRCm384137,319,696 - 137,357,759 (-)ENTREZGENE
MGSCv374136,875,611 - 136,913,652 (-)RGD
Celera4135,540,002 - 135,577,876 (-)ENTREZGENE
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030253139   ⟹   XP_030108999
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394137,047,011 - 137,083,998 (-)NCBI
GRCm384137,319,700 - 137,346,610 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030253140   ⟹   XP_030109000
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394137,047,011 - 137,084,949 (-)NCBI
GRCm384137,319,700 - 137,356,818 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030253141   ⟹   XP_030109001
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394137,047,011 - 137,083,998 (-)NCBI
GRCm384137,319,700 - 137,346,610 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030253142   ⟹   XP_030109002
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394137,047,011 - 137,084,949 (-)NCBI
GRCm384137,319,700 - 137,357,638 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036163618   ⟹   XP_036019511
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394137,047,011 - 137,083,998 (-)NCBI
RefSeq Acc Id: XM_036163619   ⟹   XP_036019512
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394137,047,011 - 137,083,998 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001230698 (Get FASTA)   NCBI Sequence Viewer  
  NP_033991 (Get FASTA)   NCBI Sequence Viewer  
  XP_030108999 (Get FASTA)   NCBI Sequence Viewer  
  XP_030109000 (Get FASTA)   NCBI Sequence Viewer  
  XP_030109001 (Get FASTA)   NCBI Sequence Viewer  
  XP_030109002 (Get FASTA)   NCBI Sequence Viewer  
  XP_036019511 (Get FASTA)   NCBI Sequence Viewer  
  XP_036019512 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA37410 (Get FASTA)   NCBI Sequence Viewer  
  AAB40051 (Get FASTA)   NCBI Sequence Viewer  
  AAC00028 (Get FASTA)   NCBI Sequence Viewer  
  AAH64792 (Get FASTA)   NCBI Sequence Viewer  
  AAK14822 (Get FASTA)   NCBI Sequence Viewer  
  BAB22563 (Get FASTA)   NCBI Sequence Viewer  
  BAC34669 (Get FASTA)   NCBI Sequence Viewer  
  BAC35825 (Get FASTA)   NCBI Sequence Viewer  
  BAE25778 (Get FASTA)   NCBI Sequence Viewer  
  BAE26572 (Get FASTA)   NCBI Sequence Viewer  
  BAE30100 (Get FASTA)   NCBI Sequence Viewer  
  BAE30644 (Get FASTA)   NCBI Sequence Viewer  
  BAE32098 (Get FASTA)   NCBI Sequence Viewer  
  BAE32891 (Get FASTA)   NCBI Sequence Viewer  
  BAE35111 (Get FASTA)   NCBI Sequence Viewer  
  BAE38678 (Get FASTA)   NCBI Sequence Viewer  
  BAE39325 (Get FASTA)   NCBI Sequence Viewer  
  BAE39489 (Get FASTA)   NCBI Sequence Viewer  
  BAE39663 (Get FASTA)   NCBI Sequence Viewer  
  BAE40000 (Get FASTA)   NCBI Sequence Viewer  
  BAE40049 (Get FASTA)   NCBI Sequence Viewer  
  BAE40062 (Get FASTA)   NCBI Sequence Viewer  
  BAE40222 (Get FASTA)   NCBI Sequence Viewer  
  BAE40595 (Get FASTA)   NCBI Sequence Viewer  
  BAE40647 (Get FASTA)   NCBI Sequence Viewer  
  BAE40902 (Get FASTA)   NCBI Sequence Viewer  
  BAE41001 (Get FASTA)   NCBI Sequence Viewer  
  BAE41379 (Get FASTA)   NCBI Sequence Viewer  
  EDL29921 (Get FASTA)   NCBI Sequence Viewer  
  P60766 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_033991   ⟸   NM_009861
- Peptide Label: isoform 1
- UniProtKB: P60766 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001230698   ⟸   NM_001243769
- Peptide Label: isoform 2
- UniProtKB: P60766 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030109002   ⟸   XM_030253142
- Peptide Label: isoform X2
RefSeq Acc Id: XP_030109000   ⟸   XM_030253140
- Peptide Label: isoform X1
RefSeq Acc Id: XP_030108999   ⟸   XM_030253139
- Peptide Label: isoform X1
RefSeq Acc Id: XP_030109001   ⟸   XM_030253141
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000054634   ⟸   ENSMUST00000051477
RefSeq Acc Id: ENSMUSP00000030417   ⟸   ENSMUST00000030417
RefSeq Acc Id: XP_036019511   ⟸   XM_036163618
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036019512   ⟸   XM_036163619
- Peptide Label: isoform X2

Promoters
RGD ID:6835062
Promoter ID:MM_KWN:40245
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   MEF_B6
Transcripts:AK040105_A430061O12RIK,   UC008VIY.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364136,892,526 - 136,893,026 (-)MPROMDB
RGD ID:6885144
Promoter ID:EPDNEW_M6023
Type:initiation region
Name:Cdc42_1
Description:Mus musculus cell division cycle 42 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384137,357,677 - 137,357,737EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:106211 AgrOrtholog
Ensembl Genes ENSMUSG00000006699 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000030417 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000054634 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000030417 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000051477 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Cdc42 UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase_Rho UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12540 UniProtKB/Swiss-Prot
MGD MGI:106211 ENTREZGENE
NCBI Gene 12540 ENTREZGENE
Pfam Ras UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cdc42 PhenoGen
PROSITE RHO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs small_GTP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CDC42_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UL78_MOUSE UniProtKB/TrEMBL
  Q99JI7_MOUSE UniProtKB/TrEMBL
UniProt Secondary A2A9U6 UniProtKB/Swiss-Prot
  P21181 UniProtKB/Swiss-Prot
  P25763 UniProtKB/Swiss-Prot
  Q3THZ7 UniProtKB/Swiss-Prot
  Q3TJK6 UniProtKB/Swiss-Prot
  Q545V0 UniProtKB/Swiss-Prot
  Q6P201 UniProtKB/Swiss-Prot
  Q8BQ51 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-07-10 Cdc42  cell division cycle 42  Cdc42  cell division cycle 42 homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED