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Gene: Cpsf3 (cleavage and polyadenylation specificity factor 3) Mus musculus
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Symbol: Cpsf3
Name: cleavage and polyadenylation specificity factor 3
Description: Exhibits 5'-3' exonuclease activity; RNA binding activity; and endoribonuclease activity. Involved in mRNA 3'-end processing by stem-loop binding activity and cleavage. Localizes to the mRNA cleavage and polyadenylation specificity factor complex. Orthologous to human CPSF3 (cleavage and polyadenylation specific factor 3); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; mRNA decay pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; clofibrate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cleavage and polyadenylation specificity factor 73 kDa subunit; cleavage and polyadenylation specificity factor subunit 3; CPSF 73 kDa subunit; MGC118660; mRNA 3'-end-processing endonuclease CPSF-73
Orthologs:
Homo sapiens (human) : CPSF3 (cleavage and polyadenylation specific factor 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cpsf3 (cleavage and polyadenylation specific factor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cpsf3 (cleavage and polyadenylation specific factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CPSF3 (cleavage and polyadenylation specific factor 3)
Canis lupus familiaris (dog) : CPSF3 (cleavage and polyadenylation specific factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cpsf3 (cleavage and polyadenylation specific factor 3)
Sus scrofa (pig) : CPSF3 (cleavage and polyadenylation specific factor 3)
Chlorocebus sabaeus (African green monkey) : CPSF3 (cleavage and polyadenylation specific factor 3)
Heterocephalus glaber (naked mole-rat) : Cpsf3 (cleavage and polyadenylation specific factor 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1221,285,391 - 21,315,056 (+)Ensembl
GRCm381221,286,273 - 21,315,056 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371221,292,158 - 21,320,917 (+)NCBIGRCm37mm9NCBIm37
MGSCv361221,532,916 - 21,561,324 (+)NCBImm8
Celera1219,589,812 - 19,618,910 (-)NCBICelera
Cytogenetic Map12 A1.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cpsf3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313999
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.