Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Kcnma1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1) Mus musculus
Analyze
Symbol: Kcnma1
Name: potassium large conductance calcium-activated channel, subfamily M, alpha member 1
Description: Exhibits identical protein binding activity; large conductance calcium-activated potassium channel activity; and voltage-gated potassium channel activity. Involved in several processes, including adult walking behavior; eye blink reflex; and locomotor rhythm. Localizes to several cellular components, including the apical plasma membrane; external side of plasma membrane; and voltage-gated potassium channel complex. Predicted to colocalize with the mitochondrion. Human ortholog(s) of this gene implicated in Alzheimer's disease and idiopathic generalized epilepsy. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human KCNMA1 (potassium calcium-activated channel subfamily M alpha 1); INTERACTS WITH 1,2-dichloroethane; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5730414M22Rik; BK channel alpha subunit; BKCa; BKCA alpha; calcium-activated potassium channel subunit alpha-1; calcium-activated potassium channel, subfamily M subunit alpha-1; k(VCA)alpha; KCa1.1; maxi K channel; MaxiK; mSlo; mSlo1; RIKEN cDNA 5730414M22 gene; Slo; slo homolog; slo-alpha; Slo1; slowpoke homolog
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1423,289,431 - 24,014,491 (-)Ensembl
GRCm381423,292,288 - 24,005,110 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371424,117,983 - 24,823,427 (-)NCBIGRCm37mm9NCBIm37
MGSCv361422,088,573 - 22,792,482 (-)NCBImm8
Celera1419,676,510 - 20,379,488 (-)NCBICelera
Cytogenetic Map14A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences