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Gene: Ctnna1 (catenin (cadherin associated protein), alpha 1) Mus musculus
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Symbol: Ctnna1
Name: catenin (cadherin associated protein), alpha 1
Description: Exhibits actin filament binding activity and identical protein binding activity. Involved in several processes, including apical junction assembly; negative regulation of neuroblast proliferation; and regulation of signal transduction. Localizes to several cellular components, including the flotillin complex; intercalated disc; and zonula adherens. Used to study patterned macular dystrophy 2. Human ortholog(s) of this gene implicated in patterned macular dystrophy 2. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human CTNNA1 (catenin alpha 1); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; endometrial cancer pathway; INTERACTS WITH 17beta-hydroxy-5alpha-androstan-3-one; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 102 kDa cadherin-associated protein; 2010010M04Rik; AA517462; AI988031; alpha E catenin; alpha E-catenin; alpha(E)-catenin; cadherin associated protein; CAP102; catenin alpha 1; catenin alpha-1; Catna1
Orthologs:
Homo sapiens (human) : CTNNA1 (catenin alpha 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ctnna1 (catenin alpha 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ctnna1 (catenin alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CTNNA1 (catenin alpha 1)
Canis lupus familiaris (dog) : CTNNA1 (catenin alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ctnna1 (catenin alpha 1)
Sus scrofa (pig) : CTNNA1 (catenin alpha 1)
Chlorocebus sabaeus (African green monkey) : CTNNA1 (catenin alpha 1)
Heterocephalus glaber (naked mole-rat) : Ctnna1 (catenin alpha 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1835,118,859 - 35,254,779 (+)Ensembl
GRCm381835,118,902 - 35,254,776 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371835,278,566 - 35,414,429 (+)NCBIGRCm37mm9NCBIm37
MGSCv361835,244,886 - 35,380,749 (+)NCBImm8
Celera1835,608,364 - 35,710,407 (+)NCBICelera
Cytogenetic Map18 B1NCBI
cM Map1818.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ctnna1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553700
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-01-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.