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Gene: Ctnna1 (catenin (cadherin associated protein), alpha 1) Mus musculus
Symbol: Ctnna1
Name: catenin (cadherin associated protein), alpha 1
Description: Exhibits actin filament binding activity and identical protein binding activity. Involved in several processes, including apical junction assembly; negative regulation of neuroblast proliferation; and regulation of signal transduction. Localizes to several cellular components, including the flotillin complex; intercalated disc; and zonula adherens. Used to study patterned macular dystrophy 2. Human ortholog(s) of this gene implicated in patterned macular dystrophy 2. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human CTNNA1 (catenin alpha 1); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; endometrial cancer pathway; INTERACTS WITH 17beta-hydroxy-5alpha-androstan-3-one; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
Also known as: 102 kDa cadherin-associated protein; 2010010M04Rik; AA517462; AI988031; alpha E catenin; alpha E-catenin; alpha(E)-catenin; cadherin associated protein; CAP102; catenin alpha 1; catenin alpha-1; Catna1
Homo sapiens (human) : CTNNA1 (catenin alpha 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ctnna1 (catenin alpha 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ctnna1 (catenin alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CTNNA1 (catenin alpha 1)
Canis lupus familiaris (dog) : CTNNA1 (catenin alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ctnna1 (catenin alpha 1)
Sus scrofa (pig) : CTNNA1 (catenin alpha 1)
Chlorocebus sabaeus (African green monkey) : CTNNA1 (catenin alpha 1)
Heterocephalus glaber (naked mole-rat) : Ctnna1 (catenin alpha 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1835,118,859 - 35,254,779 (+)Ensembl
GRCm381835,118,902 - 35,254,776 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371835,278,566 - 35,414,429 (+)NCBIGRCm37mm9NCBIm37
MGSCv361835,244,886 - 35,380,749 (+)NCBImm8
Celera1835,608,364 - 35,710,407 (+)NCBICelera
Cytogenetic Map18 B1NCBI
cM Map1818.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ctnna1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553700
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-01-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.