Cldn11 (claudin 11) - Rat Genome Database

Name: Cldn11
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Advanced Search (OLGA)

Gene: Cldn11 (claudin 11) Mus musculus

Analyze

Symbol:

Cldn11

Name:

claudin 11

RGD ID:

737604

MGI Page

MGI

Description:

Predicted to enable identical protein binding activity. Acts upstream of or within axon ensheathment; cell adhesion; and spermatogenesis. Located in basal part of cell and bicellular tight junction. Is expressed in several structures, including alimentary system; autopod; meninges; pectoralis; and sensory organ. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 22. Orthologous to human CLDN11 (claudin 11).

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

claudin-11; Claudin11; oligodendrocyte transmembrane protein; oligodendrocyte-specific protein; Osp; Ot; Otm

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CLDN11 (claudin 11)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Cldn11 (claudin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cldn11 (claudin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CLDN11 (claudin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CLDN11 (claudin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cldn11 (claudin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CLDN11 (claudin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CLDN11 (claudin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cldn11 (claudin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Cldn11 (claudin 11)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	CLDN11 (claudin 11)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cldn11b (claudin 11b)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB\|ZFIN)
Danio rerio (zebrafish):	cldn11a (claudin 11a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Xenopus tropicalis (tropical clawed frog):	cldn11	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	31,204,069 - 31,218,475 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	31,204,069 - 31,218,473 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	31,149,920 - 31,164,326 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	31,149,920 - 31,164,324 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	31,048,913 - 31,063,240 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	31,340,869 - 31,355,196 (+)	NCBI		MGSCv36	mm8
Celera	3	31,063,978 - 31,078,367 (+)	NCBI		Celera
Cytogenetic Map	3	A3	NCBI
cM Map	3	15.14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Animal Disease Models (ISO)

Fanconi-Bickel syndrome (ISO)

hypomyelinating leukodystrophy 22 (ISO)

Marfanoid Mental Retardation Syndrome, Autosomal (ISO)

multiple sclerosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

2-palmitoylglycerol (ISO)

3,4-dichloroaniline (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

4-hydroxynon-2-enal (EXP)

4-phenylbutyric acid (EXP)

6-propyl-2-thiouracil (ISO)

acrolein (ISO)

all-trans-retinoic acid (EXP,ISO)

alpha-pinene (ISO)

amitrole (ISO)

ammonium chloride (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (EXP)

arsenous acid (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

busulfan (EXP)

cadmium dichloride (EXP)

caffeine (ISO)

calcitriol (ISO)

carbendazim (ISO)

CGP 52608 (ISO)

chromium(6+) (ISO)

cobalt dichloride (ISO)

cocaine (ISO)

copper atom (ISO)

copper(0) (ISO)

crocidolite asbestos (ISO)

Cuprizon (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (ISO)

dexamethasone (ISO)

dextran sulfate (EXP)

diarsenic trioxide (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

diethylstilbestrol (ISO)

diuron (ISO)

dorsomorphin (ISO)

entinostat (ISO)

flavonoids (ISO)

fulvestrant (ISO)

furan (ISO)

genistein (EXP)

gentamycin (ISO)

GW 4064 (EXP)

haloperidol (EXP)

hydrogen sulfide (EXP)

iprodione (ISO)

ivermectin (ISO)

ketamine (ISO)

lead diacetate (ISO)

lead(0) (EXP)

mercury dibromide (ISO)

methimazole (ISO)

methylmercury chloride (ISO)

mifepristone (ISO)

mono(2-ethylhexyl) phthalate (EXP,ISO)

nickel atom (ISO)

nickel sulfate (ISO)

ozone (EXP,ISO)

paraquat (ISO)

perfluorohexanesulfonic acid (EXP)

perfluorooctane-1-sulfonic acid (EXP)

perfluorooctanoic acid (EXP)

phenylmercury acetate (ISO)

potassium dichromate (EXP,ISO)

quercetin (EXP)

resveratrol (ISO)

rotenone (ISO)

Salidroside (EXP)

SB 203580 (EXP)

SB 431542 (ISO)

serpentine asbestos (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium fluoride (EXP)

sodium sulfide (anhydrous) (EXP)

stigmasterol (EXP)

streptozocin (EXP)

sulfur dioxide (EXP)

tetracycline (ISO)

titanium dioxide (EXP)

trichostatin A (ISO)

trimellitic anhydride (EXP)

Triptolide (EXP)

trovafloxacin (EXP)

valproic acid (ISO)

vinclozolin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axon ensheathment (IMP)

bicellular tight junction assembly (IBA)

calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (ISS)

cell adhesion (IBA,IMP)

spermatogenesis (IMP)

tight junction assembly (IEA,ISO)

Cellular Component

axon (IEA,ISO)

basal part of cell (IDA)

bicellular tight junction (IBA,IDA,ISS,TAS)

cell junction (ISO)

lipid droplet (IEA,ISO)

myelin sheath (HDA)

neurofilament (IEA,ISO)

plasma membrane (IBA,ISO,TAS)

tight junction (IDA,ISO)

Molecular Function

identical protein binding (ISO,ISS)

protein binding (IPI)

structural molecule activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

hepatitis C pathway (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal auditory brainstem response waveform shape (IAGP)

abnormal distortion product otoacoustic emission (IAGP)

abnormal gait (IEA)

abnormal grip strength (IAGP)

abnormal myelin sheath morphology (IAGP)

abnormal seminiferous tubule morphology (IAGP)

abnormal Sertoli cell barrier morphology (IAGP)

abnormal spermatogenesis (IAGP)

abnormal stria vascularis morphology (IAGP)

abnormal visual evoked potential (IAGP)

absent strial basal cell tight junctions (IAGP)

azoospermia (IAGP)

cochlear outer hair cell degeneration (IAGP)

deafness (IAGP)

decreased endocochlear potential (IAGP)

hyperactivity (IEA)

impaired coordination (IAGP)

increased blood urea nitrogen level (IEA)

increased or absent threshold for auditory brainstem response (IAGP)

increased startle reflex (IEA)

male infertility (IAGP)

small testis (IAGP)

tremors (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2.	Transforming growth factor-beta3 perturbs the inter-Sertoli tight junction permeability barrier in vitro possibly mediated via its effects on occludin, zonula occludens-1, and claudin-11.	Lui WY, etal., Endocrinology 2001 May;142(5):1865-77.
3.	Electronic Transfer of Homolog Data	MGD and Homologene mouse data transfer
4.	MGDs mouse GO annotations	MGD data from the GO Consortium
5.	MGD IEA	MGD IEA
6.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
8.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8661061	PMID:8797478	PMID:9404721	PMID:9434954	PMID:10225958	PMID:10349636	PMID:10358205	PMID:10612400	PMID:10919290	PMID:11042159	PMID:11076861	PMID:11161784
PMID:11591653	PMID:11923212	PMID:12477932	PMID:12479614	PMID:14698084	PMID:14996723	PMID:15306639	PMID:15366020	PMID:15456848	PMID:15489334	PMID:15601927	PMID:15886014
PMID:16141072	PMID:16141073	PMID:16267818	PMID:16520537	PMID:16602821	PMID:16624990	PMID:17075866	PMID:17082656	PMID:17114649	PMID:17182288	PMID:17217615	PMID:17634366
PMID:17945025	PMID:18036336	PMID:18308723	PMID:18353863	PMID:18403409	PMID:18480174	PMID:18663477	PMID:19047465	PMID:19124014	PMID:19706201	PMID:19741204	PMID:19876815
PMID:20578065	PMID:21267068	PMID:21873635	PMID:21925491	PMID:22056142	PMID:22155109	PMID:22268650	PMID:22275141	PMID:22378758	PMID:22794259	PMID:22889265	PMID:23325811
PMID:23611642	PMID:23678707	PMID:23789093	PMID:24038871	PMID:24154525	PMID:24880616	PMID:24909373	PMID:24952961	PMID:25624266	PMID:25729345	PMID:25875176	PMID:26238476
PMID:26265072	PMID:26445439	PMID:27488639	PMID:28272472	PMID:29107558	PMID:29111324	PMID:29491447	PMID:29628393	PMID:29700355	PMID:29795630	PMID:29940839	PMID:30068389
PMID:30347220	PMID:30734065	PMID:31112308	PMID:31550482	PMID:32127020	PMID:32152201	PMID:32229564	PMID:32274496	PMID:32294451	PMID:32554809	PMID:32581705	PMID:33410138
PMID:33653651	PMID:33964205	PMID:34003106	PMID:34321999	PMID:34338433	PMID:34407418	PMID:34685710	PMID:34737342	PMID:35918150	PMID:36343245	PMID:36996816	PMID:37349316
PMID:37542070	PMID:38355793	PMID:38507412	PMID:38553809

Genomics

Comparative Map Data

Cldn11
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	31,204,069 - 31,218,475 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	31,204,069 - 31,218,473 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	31,149,920 - 31,164,326 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	31,149,920 - 31,164,324 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	31,048,913 - 31,063,240 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	31,340,869 - 31,355,196 (+)	NCBI		MGSCv36	mm8
Celera	3	31,063,978 - 31,078,367 (+)	NCBI		Celera
Cytogenetic Map	3	A3	NCBI
cM Map	3	15.14	NCBI

CLDN11
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	170,418,868 - 170,434,691 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	170,418,868 - 170,454,733 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	170,136,656 - 170,152,479 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	171,619,359 - 171,634,581 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	171,619,366 - 171,634,585	NCBI
Celera	3	168,535,836 - 168,551,662 (+)	NCBI		Celera
Cytogenetic Map	3	q26.2	NCBI
HuRef	3	167,506,076 - 167,521,977 (+)	NCBI		HuRef
CHM1_1	3	170,099,809 - 170,115,631 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	173,203,212 - 173,219,032 (+)	NCBI		T2T-CHM13v2.0

Cldn11
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	114,136,234 - 114,149,539 (-)	NCBI		GRCr8
mRatBN7.2	2	112,207,745 - 112,221,050 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	112,207,745 - 112,221,050 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	118,854,213 - 118,867,509 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	116,966,771 - 116,980,065 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	111,676,502 - 111,689,756 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	115,823,541 - 115,836,846 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	115,823,538 - 115,836,846 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	135,520,050 - 135,533,355 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	116,626,427 - 116,639,732 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	116,571,388 - 116,584,694 (-)	NCBI
Celera	2	107,394,882 - 107,408,187 (-)	NCBI		Celera
Cytogenetic Map	2	q24	NCBI

Cldn11
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955420	580,588 - 595,116 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955420	580,588 - 595,052 (+)	NCBI	ChiLan1.0	ChiLan1.0

CLDN11
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	168,313,680 - 168,328,673 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	168,318,403 - 168,333,400 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	167,432,856 - 167,448,053 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	175,621,472 - 175,636,782 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	175,621,472 - 175,908,350 (+)	Ensembl	panpan1.1		panPan2

CLDN11
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	34,912,903 - 34,929,441 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	34,912,449 - 34,928,433 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	43,924,891 - 43,941,855 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	34,994,383 - 35,011,477 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	34,994,046 - 35,011,477 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	34,937,785 - 34,954,501 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	34,907,493 - 34,924,620 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	35,171,151 - 35,187,831 (+)	NCBI		UU_Cfam_GSD_1.0

Cldn11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	101,534,109 - 101,549,597 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936593	2,071,882 - 2,087,877 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936593	2,072,368 - 2,087,820 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CLDN11
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	109,075,452 - 109,090,111 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	109,075,672 - 109,089,097 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	117,956,912 - 117,970,337 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CLDN11
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	18,991,734 - 19,006,902 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	18,991,042 - 19,006,866 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666063	27,767,141 - 27,782,304 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cldn11
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	48,458,512 - 48,474,734 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	48,458,593 - 48,473,463 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	765
Count of miRNA genes:	442
Interacting mature miRNAs:	515
Transcripts:	ENSMUST00000046174
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4142399	Aec1_m	autoimmune exocrinopathy 1 (mouse)			Not determined			7586174	102690034	Mouse
4141116	Lgaq4_m	late growth adjusted QTL 4 (mouse)			Not determined			10249221	83184946	Mouse
4141563	Lgq3_m	late growth QTL 3 (mouse)			Not determined			10249221	83184946	Mouse
1357584	Splq6_m	spleen weight QTL 6 (mouse)			Not determined		3	10249221	83184946	Mouse
1301114	Ssial2_m	susceptibility to sialadenitis 2 (mouse)			Not determined		3	20174862	54180103	Mouse
26884436	Zlq3_m	zygomatic length QTL 3, 10 week (mouse)					3	3265060	142405761	Mouse
12904010	Cfq8_m	conditioned fear QTL 8 (mouse)					3	24768232	31332103	Mouse
26884427	Cvht4_m	cranial vault height 4, 10 week (mouse)					3	16054164	109707316	Mouse
4142092	Tgq13_m	triglyceride QTL 13 (mouse)			Not determined			18288168	52288168	Mouse
1357440	Hrtpq1_m	heart weight percentage QTL 1 (mouse)			Not determined		3	10249221	83184946	Mouse
4141255	W10q3_m	weight 10 weeks QTL 3 (mouse)			Not determined			10249221	83184946	Mouse
1558925	Hivan1_m	HIV-associated nephropathy 1 (mouse)			Not determined		3	7586174	68716946	Mouse
39128206	Lwq18_m	liver weight QTL 18 (mouse)					3	10249221	83184946	Mouse
13207570	Tcq12_m	total cholesterol QTL 12 (mouse)					3	16504164	130163649	Mouse
1302056	Orgwq4_m	organ weight QTL 4 (mouse)			Not determined		3	30067588	147304689	Mouse
1300559	Thypr3_m	thymocyte proliferative response 3 (mouse)			Not determined		3	4525419	38525519	Mouse
26884422	Cvht7_m	cranial vault height 7, 16 week (mouse)					3	28954149	118893649	Mouse
1301358	Eae20_m	experimental allergic encephalomyelitis 20 (mouse)			Not determined		3	11630453	45630591	Mouse

Markers in Region

Cldn11

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
MGSCv37	3	31,062,861 - 31,062,985	UniSTS	GRCm37
Celera	3	31,077,988 - 31,078,112	UniSTS
Cytogenetic Map	3	A3	UniSTS
cM Map	3	12.6	UniSTS
cM Map	3	12.6	UniSTS

U19582

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	3	31,163,636 - 31,163,716	UniSTS	GRCm38
MGSCv37	3	31,062,558 - 31,062,638	UniSTS	GRCm37
Celera	3	31,077,685 - 31,077,765	UniSTS
Cytogenetic Map	3	A3	UniSTS
cM Map	3	12.6	UniSTS
Whitehead/MRC_RH	3	336.62	UniSTS

AU048398

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	3	31,158,234 - 31,159,673	UniSTS	GRCm38
GRCm38	9	101,117,670 - 101,118,387	UniSTS	GRCm38
MGSCv37	3	31,057,156 - 31,058,595	UniSTS	GRCm37
MGSCv37	9	101,020,000 - 101,020,717	UniSTS	GRCm37
Celera	9	100,653,438 - 100,654,155	UniSTS
Celera	3	31,072,271 - 31,073,710	UniSTS
Cytogenetic Map	9	E4	UniSTS
Cytogenetic Map	3	A3	UniSTS
cM Map	3	12.6	UniSTS

Cldn11

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	3	31,163,939 - 31,164,063	UniSTS	GRCm38
MGSCv37	3	31,062,861 - 31,062,985	UniSTS	GRCm37
Celera	3	31,077,988 - 31,078,112	UniSTS
Cytogenetic Map	3	A3	UniSTS
cM Map	3	12.6	UniSTS

Cldn11

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	3	A3	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_008770	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC117590	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF124426	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK005088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK005171	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK161698	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BB798247	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC021659	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BY110541	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466530	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U19582	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000046174 ⟹ ENSMUSP00000042181

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	31,204,069 - 31,218,473 (+)	Ensembl
GRCm38.p6 Ensembl	3	31,149,920 - 31,164,324 (+)	Ensembl

RefSeq Acc Id:

NM_008770 ⟹ NP_032796

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	3	31,204,069 - 31,218,475 (+)	NCBI
GRCm38	3	31,149,920 - 31,164,326 (+)	ENTREZGENE
MGSCv37	3	31,048,913 - 31,063,240 (+)	RGD
Celera	3	31,063,907 - 31,078,375 (+)	ENTREZGENE
cM Map	3		ENTREZGENE

Sequence:

show sequence

GAGGGGGCGGGGACGCGCTGCCCAGCAGCGCTGCAGTCCCCTCCAGGCGCACCTGTCCCCGCTG
CACGCTGTCGCAGCAGTGCTTGCAGCCGCTCTCTCCCCATCTCGAGTAGCCCGGAGCCAGCGGC
TCGCGAGGGCCAAGAGGGCAAGCCTAGGGAAGGCTCTGTCCAGGACGACACAGGGGGCACAATC
CGTGTGAGTCGAGCTGCGTGGACGTCGCTGCGGCCACCATGGTAGCCACTTGCCTTCAGGTGGT
GGGTTTCGTCACGAGCTTCGTGGGTTGGATTGGCATCATCGTCACAACGTCCACCAATGACTGG
GTGGTGACCTGCAGCTACACCATCCCCACCTGCCGAAAAATGGACGAACTGGGCTCCAAGGGCC
TGTGGGCTGACTGCGTCATGGCCACTGGTCTCTACCACTGCAAACCCCTGGTGGACATCCTCAT
CCTTCCAGGCTACGTGCAGGCTTGTAGAGCCCTCATGATTGCTGCCTCCGTTCTGGGCCTGCCC
GCCATCTTGCTGCTGTTGACAGTTCTCCCCTGCATCCGAATGGGCCACGAGCCTGGAGTGGCCA
AGTACAGGCGAGCCCAGCTGGCTGGGGTGCTCCTTATTCTGCTGGCTCTCTGCGCCATTGTCGC
CACCATCTGGTTTCCTGTATGTGCCCACCGCGAGATCACCATCGTGAGCTTTGGCTACTCGCTG
TACGCAGGTTGGATCGGTGCTGTGATGTGCCTGGTGGGTGGCTGTGTCATCGTCTGCTGCTCCG
GGGATGCACAGTCATTTGGAGAAAACCGTTTCTATTACTCTTCTGGTTCCAGCTCGCCAACGCA
TGCCAAGAGTGCCCATGTCTAAGAGGGCTGCTCCACTGCCCGCCGAGGTGCTGTAAATGCTGGG
CCTGGGCCCTGGGTTTGCTCGCCACAGTGGGGAGAAGCCCACTTCCCTGCCAGGCACTAAAGCC
AAAGTTCTAGAAAGTATCCTGCCCCGGCATTTTGAAGTCGTAACACCCCACCCACCCACCCACC
ACTTCTTGGCTGCCTTAAAAGAAAGCTCTAGCTCAGTTAATGCCCACATAGTTTTCTCCTGGAG
TTGCGGGCTGTGGCTGTTTGCTCTTTCCTCGGGCATTCCATTGTTGTTGATTAAAAAAATATTT
TGTTTCTCTCTTAAATTCAAATGTCTTGGGAACATTGCTGACTTGGGTGTGGATTGGGAAAGAA
ATAAAAGATGCTTTTCAAAGGGTTACCAACGACAGTGGAAGCCTTATAGAGACAGCTCTCTTCT
CCCTTTCGGCTTAGTTTCAAGGTCACTTATATATAAGAGATAGAAATGGATAGATTGGGAACAC
GGGTGGGAGGGGAACTCAGAGCTTTCCCTCCACGGGAAGCTTCTCTTTTATAAGTTGAGGGGTT
GGGTGTCTTTTTTTTTTTAGTTTGCGATTTTACATTTTTCTGTACGTACTTTTTCAAGATTGAT
CATTTTTATAACCACGGGTTTCCTGAAAATTCTCAATTCACCAATATGAAGGAAATGAACCAAG
CAGACGTTAATATGCAATAAATAATAGTACGAAGATTATAACTTTAACTGACTGCCCACGGTTT
CCAGGTTTGTATGCTATAGTTTTTAATCCTATGGTTGCATATGCTTCAAATTAACACATTTAAA
AATCTTTTCTCCCCTTCTATTTCTGTCTCCATTCTGTTAGAGACCATGAAGCAGTATTGTTTAA
CATAAGTTGTACTGTTAAGTTTGGCTTCATGGGTGTAAACACCAATGGTCTGTCAGTGTCTAAG
ACTCTGGATACTGCAAGCTCCGTCCGGTGCATTTGTTCAGGTAAAATCTGTGCAATAAAATAAC
AAACTGTCTCCAAAGC

hide sequence

Protein Sequences


Protein RefSeqs	NP_032796	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB50270	(Get FASTA)	NCBI Sequence Viewer
	AAD17321	(Get FASTA)	NCBI Sequence Viewer
	AAH21659	(Get FASTA)	NCBI Sequence Viewer
	BAB23810	(Get FASTA)	NCBI Sequence Viewer
	BAB23860	(Get FASTA)	NCBI Sequence Viewer
	BAE36538	(Get FASTA)	NCBI Sequence Viewer
	EDL34982	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000042181
	ENSMUSP00000042181.7
GenBank Protein	Q60771	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_032796 ⟸ NM_008770

- UniProtKB:

Q545N5 (UniProtKB/Swiss-Prot), Q9DB65 (UniProtKB/Swiss-Prot), Q60771 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MVATCLQVVGFVTSFVGWIGIIVTTSTNDWVVTCSYTIPTCRKMDELGSKGLWADCVMATGLYH
CKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGHEPGVAKYRRAQLAGVLLI
LLALCAIVATIWFPVCAHREITIVSFGYSLYAGWIGAVMCLVGGCVIVCCSGDAQSFGENRFYY
SSGSSSPTHAKSAHV

hide sequence

Ensembl Acc Id:

ENSMUSP00000042181 ⟸ ENSMUST00000046174

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q60771-F1-model_v2	AlphaFold	Q60771	1-207	view protein structure

Promoters

RGD ID:

6833581

Promoter ID:

MM_KWN:33984

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Brain

Transcripts:

OTTMUST00000054268

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	3	31,048,691 - 31,049,191 (+)	MPROMDB

RGD ID:

6880434

Promoter ID:

EPDNEW_M3667

Type:

initiation region

Name:

Cldn11_1

Description:

Mus musculus claudin 11 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	3	31,149,946 - 31,150,006	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:106925	AgrOrtholog
Ensembl Genes	ENSMUSG00000037625	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000046174	ENTREZGENE
	ENSMUST00000046174.8	UniProtKB/Swiss-Prot
Gene3D-CATH	1.20.140.150	UniProtKB/Swiss-Prot
InterPro	Claudin	UniProtKB/Swiss-Prot
	Claudin11	UniProtKB/Swiss-Prot
	Claudin_CS	UniProtKB/Swiss-Prot
	PMP22/EMP/MP20/Claudin	UniProtKB/Swiss-Prot
KEGG Report	mmu:18417	UniProtKB/Swiss-Prot
MGD	MGI:106925	ENTREZGENE
NCBI Gene	18417	ENTREZGENE
PANTHER	PTHR12002	UniProtKB/Swiss-Prot
	PTHR12002:SF6	UniProtKB/Swiss-Prot
Pfam	PMP22_Claudin	UniProtKB/Swiss-Prot
PhenoGen	Cldn11	PhenoGen
PRINTS	CLAUDIN	UniProtKB/Swiss-Prot
	CLAUDIN11	UniProtKB/Swiss-Prot
PROSITE	CLAUDIN	UniProtKB/Swiss-Prot
UniProt	CLD11_MOUSE	UniProtKB/Swiss-Prot
	Q545N5	ENTREZGENE
	Q60771	ENTREZGENE
	Q9DB65	ENTREZGENE
UniProt Secondary	Q545N5	UniProtKB/Swiss-Prot
	Q9DB65	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

Mammalian Phenotype