Abcd2 (ATP-binding cassette, sub-family D member 2) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Abcd2 (ATP-binding cassette, sub-family D member 2) Mus musculus
Analyze
Symbol: Abcd2
Name: ATP-binding cassette, sub-family D member 2
RGD ID: 730968
MGI Page MGI
Description: Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and protein dimerization activity. Involved in several processes, including fatty acid catabolic process; negative regulation of biosynthetic process; and positive regulation of fatty acid metabolic process. Acts upstream of or within response to bacterium. Located in peroxisome. Is expressed in several structures, including alimentary system; hemolymphoid system; limb; nervous system; and sensory organ. Orthologous to human ABCD2 (ATP binding cassette subfamily D member 2).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: A; ABC3; ABC39; adrenoleukodystrophy related; adrenoleukodystrophy-like; adrenoleukodystrophy-related protein; AL; ALDL1; ALDR; ALDRP; ATP-binding cassette sub-family D member 2; ATP-binding cassette, sub-family D (ALD), member 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391591,029,874 - 91,076,013 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1591,030,074 - 91,076,002 (-)EnsemblGRCm39 Ensembl
GRCm381591,145,871 - 91,192,007 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1591,145,871 - 91,191,799 (-)EnsemblGRCm38mm10GRCm38
MGSCv371590,976,302 - 91,022,238 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361590,973,638 - 91,019,574 (-)NCBIMGSCv36mm8
Celera1593,253,156 - 93,299,066 (-)NCBICelera
Cytogenetic Map15E3NCBI
cM Map1546.0NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid  (EXP)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
alpha-Zearalanol  (ISO)
amitriptyline  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
aspartame  (EXP)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (ISO)
bisphenol F  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (EXP)
chlorpyrifos  (EXP)
clofibrate  (EXP)
clothianidin  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP)
delta-tocotrienol  (EXP)
dexamethasone  (EXP,ISO)
Diallyl sulfide  (ISO)
dichloroacetic acid  (EXP)
diethylstilbestrol  (ISO)
endosulfan  (ISO)
epoxiconazole  (EXP)
ethylparaben  (ISO)
fructose  (EXP)
furan  (ISO)
gentamycin  (ISO)
glucose  (EXP)
indole-3-methanol  (ISO)
indometacin  (ISO)
ketoconazole  (ISO)
lipopolysaccharide  (EXP,ISO)
maneb  (EXP)
methimazole  (ISO)
monosodium L-glutamate  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
orphenadrine  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
parathion  (EXP)
perfluorooctanoic acid  (ISO)
phenformin  (ISO)
phenobarbital  (EXP)
pirinixic acid  (EXP,ISO)
quercetin  (EXP)
resveratrol  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
Soman  (ISO)
sulfadimethoxine  (ISO)
Tesaglitazar  (ISO)
testosterone  (EXP)
tetrachloroethene  (EXP)
tetrachloromethane  (EXP,ISO)
tetracycline  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP)
tolcapone  (ISO)
trichloroethene  (EXP,ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
trovafloxacin  (EXP)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
mitochondrion  (HDA)
peroxisomal membrane  (IBA,IEA,ISO)
peroxisome  (IDA,ISO)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A Thyroid Hormone-Based Strategy for Correcting the Biochemical Abnormality in X-Linked Adrenoleukodystrophy. Hartley MD, etal., Endocrinology. 2017 May 1;158(5):1328-1338. doi: 10.1210/en.2016-1842.
2. A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern. Lombard-Platet G, etal., Proc Natl Acad Sci U S A 1996 Feb 6;93(3):1265-9.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:9195160   PMID:9345902   PMID:9887385   PMID:10196381   PMID:10329405   PMID:10349636   PMID:10504404   PMID:10551832   PMID:11042159   PMID:11076861   PMID:11087670  
PMID:11217851   PMID:11422379   PMID:12150895   PMID:12477932   PMID:14681479   PMID:14713219   PMID:15489218   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16223892   PMID:16249184  
PMID:16602821   PMID:17208939   PMID:17260006   PMID:18614015   PMID:18723473   PMID:18854420   PMID:19556607   PMID:20179078   PMID:21267068   PMID:21677750   PMID:21779340   PMID:21873635  
PMID:22493092   PMID:23012479   PMID:25043761   PMID:25123288   PMID:25255441   PMID:25446110   PMID:25822341   PMID:26098214   PMID:26241474   PMID:28258215   PMID:29222160   PMID:29997171  
PMID:30409884   PMID:30769094   PMID:32325033   PMID:34321999   PMID:35681537   PMID:36207570  


Genomics

Comparative Map Data
Abcd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391591,029,874 - 91,076,013 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1591,030,074 - 91,076,002 (-)EnsemblGRCm39 Ensembl
GRCm381591,145,871 - 91,192,007 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1591,145,871 - 91,191,799 (-)EnsemblGRCm38mm10GRCm38
MGSCv371590,976,302 - 91,022,238 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361590,973,638 - 91,019,574 (-)NCBIMGSCv36mm8
Celera1593,253,156 - 93,299,066 (-)NCBICelera
Cytogenetic Map15E3NCBI
cM Map1546.0NCBI
ABCD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381239,531,025 - 39,619,803 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1239,550,033 - 39,619,803 (-)EnsemblGRCh38hg38GRCh38
GRCh371239,943,835 - 40,013,605 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361238,232,813 - 38,300,237 (-)NCBINCBI36Build 36hg18NCBI36
Build 341238,232,813 - 38,300,237NCBI
Celera1238,749,047 - 38,818,059 (-)NCBICelera
Cytogenetic Map12q12ENTREZGENE
HuRef1236,971,383 - 37,040,198 (-)NCBIHuRef
CHM1_11239,911,021 - 39,979,850 (-)NCBICHM1_1
T2T-CHM13v2.01239,480,907 - 39,601,214 (-)NCBIT2T-CHM13v2.0
Abcd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87124,142,597 - 124,191,202 (-)NCBIGRCr8
mRatBN7.27122,263,034 - 122,311,642 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7122,263,032 - 122,311,642 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7124,054,640 - 124,103,336 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07126,280,755 - 126,329,211 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07126,207,915 - 126,256,642 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07132,294,564 - 132,343,169 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7132,294,562 - 132,343,169 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07131,968,475 - 132,017,044 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47129,542,758 - 129,591,363 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17129,577,902 - 129,626,508 (-)NCBI
Celera7118,713,620 - 118,762,172 (-)NCBICelera
Cytogenetic Map7q35NCBI
Abcd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955505721,222 - 798,470 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955505717,800 - 769,702 (+)NCBIChiLan1.0ChiLan1.0
ABCD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21054,525,947 - 54,601,622 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11254,522,683 - 54,598,358 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01249,082,122 - 49,158,524 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11249,941,914 - 50,011,140 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1249,941,914 - 50,011,140 (+)Ensemblpanpan1.1panPan2
ABCD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12714,015,093 - 14,084,362 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2714,015,091 - 14,163,312 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2732,351,661 - 32,426,133 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02714,182,734 - 14,251,081 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2714,187,982 - 14,251,183 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12713,992,155 - 14,060,013 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02714,030,140 - 14,098,038 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02732,500,349 - 32,568,488 (-)NCBIUU_Cfam_GSD_1.0
Abcd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494574,459,561 - 74,544,026 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366071,292,888 - 1,343,334 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366071,292,964 - 1,345,671 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl571,122,325 - 71,180,723 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1571,123,187 - 71,180,758 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2573,679,380 - 73,746,350 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ABCD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11135,818,451 - 35,884,696 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037210,906,997 - 210,973,843 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abcd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624778847,879 - 909,727 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624778854,297 - 912,498 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Abcd2
2248 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1001
Count of miRNA genes:536
Interacting mature miRNAs:670
Transcripts:ENSMUST00000069511
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
1301918Skull22_mskull morphology 22 (mouse)Not determined1585901546104073951Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
11530038Sluc34b_msusceptibility to lung cancer 34b (mouse)1585896437104073951Mouse
11530037Sluc34a_msusceptibility to lung cancer 34a (mouse)1585896437104073951Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1578897881104073951Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579163411104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580884933104073951Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined79908940104073951Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580313634104073951Mouse
4141511Gdcr1_mglycerolphosphate dehydrogenase regulator 1 (mouse)Not determined82615474104073951Mouse
1357614Bmca_mbile mucin accumulation (mouse)Not determined1585896437104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580884933104073951Mouse

Markers in Region
Abcd2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15E-FUniSTS
cM Map15 UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001358967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_177949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_177950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC113102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF302500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ009992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ009993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK134560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK134763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC019187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY127186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01094423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z48670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000069511   ⟹   ENSMUSP00000068940
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1591,030,074 - 91,076,002 (-)Ensembl
GRCm38.p6 Ensembl1591,145,871 - 91,191,799 (-)Ensembl
Ensembl Acc Id: ENSMUST00000229909
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1591,043,314 - 91,056,388 (-)Ensembl
GRCm38.p6 Ensembl1591,159,111 - 91,172,185 (-)Ensembl
Ensembl Acc Id: ENSMUST00000230461
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1591,072,720 - 91,074,901 (-)Ensembl
GRCm38.p6 Ensembl1591,188,517 - 91,190,698 (-)Ensembl
RefSeq Acc Id: NM_001358967   ⟹   NP_001345896
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391591,029,874 - 91,076,013 (-)NCBI
GRCm381591,145,871 - 91,192,007 (-)NCBI
Sequence:
RefSeq Acc Id: NM_011994   ⟹   NP_036124
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391591,029,874 - 91,076,013 (-)NCBI
GRCm381591,145,871 - 91,192,007 (-)NCBI
MGSCv371590,976,302 - 91,022,238 (-)RGD
Celera1593,253,156 - 93,299,066 (-)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_177949
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391591,029,874 - 91,076,013 (-)NCBI
RefSeq Acc Id: NR_177950
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391591,029,874 - 91,076,013 (-)NCBI
RefSeq Acc Id: NP_036124   ⟸   NM_011994
- Peptide Label: isoform 1
- UniProtKB: Q8BQ63 (UniProtKB/Swiss-Prot),   Q8C4B6 (UniProtKB/Swiss-Prot),   Q61285 (UniProtKB/Swiss-Prot),   A0A0R4J0U5 (UniProtKB/TrEMBL),   Q3TU16 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001345896   ⟸   NM_001358967
- Peptide Label: isoform 2
- UniProtKB: Q3TU16 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000068940   ⟸   ENSMUST00000069511
Protein Domains
ABC transmembrane type-1   ABC transporter

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61285-F1-model_v2 AlphaFold Q61285 1-741 view protein structure

Promoters
RGD ID:6825651
Promoter ID:MM_KWN:19464
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_011994
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361591,022,116 - 91,022,647 (-)MPROMDB
RGD ID:8684780
Promoter ID:EPDNEW_M20420
Type:initiation region
Name:Abcd2_1
Description:Mus musculus ATP-binding cassette, sub-family D , member 2 ,transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381591,191,780 - 91,191,840EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1349467 AgrOrtholog
Ensembl Genes ENSMUSG00000055782 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000069511 ENTREZGENE
  ENSMUST00000069511.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1560.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC1_TM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC1_TM_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_transporter-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_transporter_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_transporter_sub-D UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:26874 UniProtKB/Swiss-Prot
MGD MGI:1349467 ENTREZGENE
NCBI Gene 26874 ENTREZGENE
PANTHER ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11384:SF24 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ABC_membrane_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_tran UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Abcd2 PhenoGen
PROSITE ABC_TM1F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_TRANSPORTER_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF90123 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J0U5 ENTREZGENE
  ABCD2_MOUSE UniProtKB/Swiss-Prot
  Q3TU16 ENTREZGENE, UniProtKB/TrEMBL
  Q3UYE0_MOUSE UniProtKB/TrEMBL
  Q61285 ENTREZGENE
  Q8BQ63 ENTREZGENE
  Q8C4B6 ENTREZGENE
UniProt Secondary A0A0R4J0U5 UniProtKB/Swiss-Prot
  Q8BQ63 UniProtKB/Swiss-Prot
  Q8C4B6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-27 Abcd2  ATP-binding cassette, sub-family D member 2  Abcd2  ATP-binding cassette, sub-family D (ALD), member 2  Symbol and/or name change 5135510 APPROVED