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Gene: Slc1a2 (solute carrier family 1 (glial high affinity glutamate transporter), member 2) Mus musculus
Symbol: Slc1a2
Name: solute carrier family 1 (glial high affinity glutamate transporter), member 2
Description: Exhibits high-affinity glutamate transmembrane transporter activity. Involved in several processes, including growth; neurotransmitter uptake; and positive regulation of glucose import. Localizes to the axolemma; glutamatergic synapse; and integral component of plasma membrane. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 41. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and spinal cord. Orthologous to human SLC1A2 (solute carrier family 1 member 2); PARTICIPATES IN amyotrophic lateral sclerosis pathway; glutamate signaling pathway; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700091C19Rik; 2900019G14Rik; AI159670; Eaat2; EAAT2 variant mEAAT2/5UT2; EAAT2 variant mEAAT2/5UT5; excitatory amino acid transporter 2; glial high affinity glutamate transporter; GLT-1; GLT1; glutamate transporter 1c; MGLT1; RIKEN cDNA 2900019G14 gene; sodium-dependent glutamate/aspartate transporter 2; solute carrier family 1 member 2; solute carrier family 1, member 2
Homo sapiens (human) : SLC1A2 (solute carrier family 1 member 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Slc1a2 (solute carrier family 1 member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc1a2 (solute carrier family 1 member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC1A2 (solute carrier family 1 member 2)
Canis lupus familiaris (dog) : SLC1A2 (solute carrier family 1 member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc1a2 (solute carrier family 1 member 2)
Sus scrofa (pig) : SLC1A2 (solute carrier family 1 member 2)
Chlorocebus sabaeus (African green monkey) : SLC1A2 (solute carrier family 1 member 2)
Heterocephalus glaber (naked mole-rat) : Slc1a2 (solute carrier family 1 member 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl2102,658,659 - 102,790,784 (+)Ensembl
GRCm382102,658,239 - 102,790,784 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372102,498,840 - 102,630,941 (+)NCBIGRCm37mm9NCBIm37
MGSCv362102,507,277 - 102,578,945 (+)NCBImm8
Celera2103,898,008 - 104,034,664 (+)NCBICelera
Cytogenetic Map2E2NCBI
cM Map254.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Slc1a2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736773
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.