(+)-pilocarpine multiple interactions ISO RGD:2848 6480464 Carbamazepine inhibits the reaction [Pilocarpine affects the reaction [mesulergine binds to HTR2C protein]] more ... CTD PMID:19439326 , PMID:19700373 (+)-pilocarpine increases expression ISO RGD:2848 6480464 Pilocarpine results in increased expression of HTR2C mRNA, Pilocarpine results in increased expression of HTR2C protein CTD PMID:19700373 (+)-pilocarpine decreases expression ISO RGD:2848 6480464 Pilocarpine results in decreased expression of HTR2C mRNA, Pilocarpine results in decreased expression of HTR2C protein CTD PMID:19439326 1,2-dichloroethane affects expression EXP 6480464 ethylene dichloride affects the expression of HTR2C mRNA CTD PMID:28960355 1-(3-chlorophenyl)piperazine multiple interactions EXP 6480464 [1-(3-chlorophenyl)piperazine binds to and results in increased activity of HTR2C protein] which results in increased susceptibility to Cocaine CTD PMID:10541732 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile affects binding ISO RGD:736842 6480464 Citalopram binds to HTR2C protein CTD PMID:18083778 1-bromopropane increases expression ISO RGD:2848 6480464 1-bromopropane results in increased expression of HTR2C mRNA CTD PMID:19576243 17beta-estradiol affects expression ISO RGD:2848 6480464 Estradiol affects the expression of HTR2C mRNA CTD PMID:12008023 17beta-estradiol increases expression ISO RGD:2848 6480464 Estradiol results in increased expression of HTR2C mRNA CTD PMID:20068009 17beta-estradiol multiple interactions ISO RGD:2848 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in decreased expression of HTR2C mRNA more ... CTD PMID:18650020 , PMID:32741896 17beta-estradiol 3-benzoate multiple interactions ISO RGD:2848 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in decreased expression of HTR2C mRNA CTD PMID:32741896 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:2848 6480464 Tetrachlorodibenzodioxin results in increased expression of HTR2C mRNA CTD PMID:23871856 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine affects binding ISO RGD:736842 6480464 4-iodo-2, 5-dimethoxyphenylisopropylamine binds to HTR2C protein CTD PMID:9857084 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine multiple interactions ISO RGD:736842 6480464 1-(8-bromobenzo(1 more ... CTD PMID:9857084 2-chloro-6-(1-piperazinyl)pyrazine multiple interactions ISO RGD:2848 6480464 6-chloro-2-(1-piperazinyl)pyrazine binds to and results in increased activity of HTR2C protein CTD PMID:16521035 2-chloro-6-(1-piperazinyl)pyrazine multiple interactions EXP 6480464 [6-chloro-2-(1-piperazinyl)pyrazine binds to and results in increased activity of HTR2C protein] which results in increased susceptibility to Cocaine CTD PMID:10541732 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:2848 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of HTR2C protein CTD PMID:26068050 3,4-methylenedioxymethamphetamine multiple interactions ISO RGD:736842 6480464 N-Methyl-3, 4-methylenedioxyamphetamine inhibits the reaction [mesulergine binds to HTR2C protein] CTD PMID:29458138 6-propyl-2-thiouracil increases expression ISO RGD:2848 6480464 Propylthiouracil results in increased expression of HTR2C mRNA CTD PMID:24780913 , PMID:25825206 aflatoxin B1 affects expression ISO RGD:736842 6480464 Aflatoxin B1 affects the expression of HTR2C protein CTD PMID:20106945 aflatoxin B1 increases methylation ISO RGD:736842 6480464 Aflatoxin B1 results in increased methylation of HTR2C intron CTD PMID:30157460 aflatoxin B1 decreases methylation ISO RGD:736842 6480464 Aflatoxin B1 results in decreased methylation of HTR2C gene CTD PMID:27153756 agomelatine affects binding ISO RGD:736842 6480464 S 20098 analog binds to HTR2C protein, S 20098 binds to HTR2C protein CTD PMID:22301214 all-trans-retinoic acid decreases expression ISO RGD:736842 6480464 Tretinoin results in decreased expression of HTR2C mRNA CTD PMID:21934132 amitriptyline affects binding ISO RGD:736842 6480464 Amitriptyline binds to HTR2C protein CTD PMID:18083778 ammonium chloride affects expression ISO RGD:2848 6480464 Ammonium Chloride affects the expression of HTR2C mRNA CTD PMID:16483693 aripiprazole multiple interactions ISO RGD:736842 6480464 Aripiprazole binds to and affects the activity of HTR2C protein CTD PMID:21823597 arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of HTR2C mRNA CTD PMID:33053406 arsenite(3-) increases methylation ISO RGD:736842 6480464 arsenite results in increased methylation of HTR2C promoter CTD PMID:23974009 atrazine affects methylation ISO RGD:2848 6480464 Atrazine affects the methylation of HTR2C gene CTD PMID:28931070 Bardoxolone methyl decreases activity ISO RGD:736842 6480464 bardoxolone methyl results in decreased activity of HTR2C protein CTD PMID:28790194 benzo[a]pyrene affects methylation ISO RGD:736842 6480464 Benzo(a)pyrene affects the methylation of HTR2C 3' UTR more ... CTD PMID:27901495 bis(2-chloroethyl) sulfide increases expression EXP 6480464 Mustard Gas results in increased expression of HTR2C mRNA CTD PMID:15674844 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of HTR2C mRNA CTD PMID:33484791 bisphenol A decreases expression ISO RGD:2848 6480464 bisphenol A results in decreased expression of HTR2C mRNA CTD PMID:25181051 more ... bisphenol A multiple interactions ISO RGD:2848 6480464 [bisphenol A co-treated with Genistein] results in increased methylation of HTR2C gene CTD PMID:28505145 bisphenol A increases methylation ISO RGD:2848 6480464 bisphenol A results in increased methylation of HTR2C gene CTD PMID:28505145 bisphenol F decreases expression ISO RGD:2848 6480464 4, 4'-bisphenol F results in decreased expression of HTR2C mRNA CTD PMID:26186136 calcitriol multiple interactions ISO RGD:736842 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of HTR2C mRNA CTD PMID:21592394 calcitriol increases expression ISO RGD:736842 6480464 Calcitriol results in increased expression of HTR2C mRNA CTD PMID:16002434 , PMID:21592394 carbamazepine multiple interactions ISO RGD:2848 6480464 Carbamazepine inhibits the reaction [Pilocarpine affects the reaction [mesulergine binds to HTR2C protein]] more ... CTD PMID:19439326 , PMID:19700373 chlorpyrifos decreases expression ISO RGD:2848 6480464 Chlorpyrifos results in decreased expression of HTR2C mRNA CTD PMID:18668222 citalopram affects binding ISO RGD:736842 6480464 Citalopram binds to HTR2C protein CTD PMID:18083778 clomipramine affects binding ISO RGD:736842 6480464 Clomipramine binds to HTR2C protein CTD PMID:18083778 clomipramine increases expression ISO RGD:2848 6480464 Clomipramine results in increased expression of HTR2C protein CTD PMID:20619828 clozapine affects binding ISO RGD:736842 6480464 Clozapine binds to HTR2C protein CTD PMID:16983399 clozapine decreases expression ISO RGD:2848 6480464 Clozapine results in decreased expression of HTR2C mRNA CTD PMID:17868938 clozapine affects binding ISO RGD:2848 6480464 Clozapine binds to HTR2C protein CTD PMID:9723970 clozapine affects response to substance ISO RGD:736842 6480464 HTR2C gene polymorphism affects the susceptibility to Clozapine more ... CTD PMID:12668355 more ... cocaine multiple interactions EXP 6480464 [1-(3-chlorophenyl)piperazine binds to and results in increased activity of HTR2C protein] which results in increased susceptibility to Cocaine more ... CTD PMID:10541732 , PMID:12427861 cocaine decreases expression ISO RGD:2848 6480464 Cocaine results in decreased expression of HTR2C mRNA CTD PMID:16076954 cocaine increases response to substance EXP 6480464 HTR2C mutant form results in increased susceptibility to Cocaine CTD PMID:12427861 Cuprizon affects expression ISO RGD:2848 6480464 Cuprizone affects the expression of HTR2C mRNA CTD PMID:26577399 cyclosporin A decreases expression ISO RGD:736842 6480464 Cyclosporine results in decreased expression of HTR2C mRNA CTD PMID:20106945 diazinon decreases expression ISO RGD:2848 6480464 Diazinon results in decreased expression of HTR2C mRNA CTD PMID:17452286 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of HTR2C mRNA CTD PMID:21266533 dibutyl phthalate increases expression ISO RGD:2848 6480464 Dibutyl Phthalate results in increased expression of HTR2C mRNA CTD PMID:15620428 dieldrin affects expression ISO RGD:2848 6480464 Dieldrin affects the expression of HTR2C mRNA CTD PMID:18835401 dioxygen increases expression ISO RGD:736842 6480464 Oxygen deficiency results in increased expression of HTR2C mRNA CTD PMID:24236059 dopamine multiple interactions EXP 6480464 HTR2C protein affects the reaction [Cocaine results in increased abundance of Dopamine] CTD PMID:12427861 dorsomorphin multiple interactions ISO RGD:736842 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of HTR2C mRNA CTD PMID:27188386 entinostat increases expression ISO RGD:736842 6480464 entinostat results in increased expression of HTR2C mRNA CTD PMID:26272509 ethanol affects splicing EXP 6480464 Ethanol affects the splicing of HTR2C mRNA CTD PMID:30319688 fenfluramine affects binding ISO RGD:736842 6480464 Fenfluramine binds to HTR2C protein CTD PMID:10617681 fenvalerate increases expression ISO RGD:2848 6480464 fenvalerate results in increased expression of HTR2C mRNA CTD PMID:30307764 fluoxetine affects binding ISO RGD:736842 6480464 Fluoxetine binds to HTR2C protein CTD PMID:18083778 fluoxetine multiple interactions EXP 6480464 [[Fluoxetine binds to and results in increased activity of HTR2C protein] which results in increased phosphorylation of and results in increased activity of EGFR protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein more ... CTD PMID:19662385 fluoxetine multiple interactions ISO RGD:2848 6480464 [Fluoxetine results in increased abundance of Serotonin] which results in decreased expression of HTR2C mRNA more ... CTD PMID:21554931 , PMID:9050900 fluoxetine increases expression EXP 6480464 Fluoxetine results in increased expression of HTR2C mRNA, Fluoxetine results in increased expression of HTR2C mRNA alternative form CTD PMID:15659601 , PMID:21083617 fluphenazine affects binding ISO RGD:736842 6480464 Fluphenazine binds to HTR2C protein CTD PMID:17606915 folic acid increases expression EXP 6480464 Folic Acid results in increased expression of HTR2C mRNA CTD PMID:25006883 genistein multiple interactions ISO RGD:2848 6480464 [bisphenol A co-treated with Genistein] results in increased methylation of HTR2C gene CTD PMID:28505145 haloperidol decreases expression ISO RGD:2848 6480464 Haloperidol results in decreased expression of HTR2C mRNA CTD PMID:17868938 imidacloprid increases expression ISO RGD:2848 6480464 imidacloprid results in increased expression of HTR2C mRNA CTD PMID:27782041 lead diacetate affects expression ISO RGD:2848 6480464 lead acetate affects the expression of HTR2C mRNA CTD PMID:21864555 lead diacetate decreases expression ISO RGD:2848 6480464 lead acetate results in decreased expression of HTR2C mRNA CTD PMID:22641619 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of HTR2C mRNA CTD PMID:12057914 lipopolysaccharide affects response to substance ISO RGD:2848 6480464 HTR2C protein affects the susceptibility to Lipopolysaccharides CTD PMID:12479973 loxapine affects binding ISO RGD:2848 6480464 Loxapine analog binds to HTR2C protein, Loxapine binds to HTR2C protein CTD PMID:9723970 mesulergine affects binding ISO RGD:736842 6480464 mesulergine binds to HTR2C protein CTD PMID:18083778 , PMID:29458138 mesulergine multiple interactions ISO RGD:736842 6480464 N-Methyl-3, 4-methylenedioxyamphetamine inhibits the reaction [mesulergine binds to HTR2C protein] CTD PMID:29458138 mesulergine affects binding ISO RGD:2848 6480464 mesulergine binds to HTR2C protein CTD PMID:19439326 , PMID:19700373 mesulergine multiple interactions ISO RGD:2848 6480464 Carbamazepine inhibits the reaction [Pilocarpine affects the reaction [mesulergine binds to HTR2C protein]] more ... CTD PMID:19439326 , PMID:19700373 methamphetamine multiple interactions EXP 6480464 [Mianserin binds to and results in decreased activity of HTR2C protein] which results in decreased susceptibility to Methamphetamine CTD PMID:15213358 methamphetamine affects response to substance ISO RGD:2848 6480464 HTR2C protein affects the susceptibility to Methamphetamine CTD PMID:11751031 methoxychlor decreases expression ISO RGD:2848 6480464 Methoxychlor results in decreased expression of HTR2C mRNA CTD PMID:27103539 mianserin increases expression ISO RGD:736842 6480464 Mianserin results in increased expression of HTR2C protein CTD PMID:18083778 mianserin multiple interactions ISO RGD:736842 6480464 6-chloro-5-methyl-1-((2-(2-methylpyrid-3-yloxy)pyrid-5-yl)carbamoyl)indoline inhibits the reaction [Mianserin results in increased expression of HTR2C protein], Mianserin binds to and affects the activity of HTR2C protein CTD PMID:18083778 mianserin multiple interactions EXP 6480464 [Mianserin binds to and results in decreased activity of HTR2C protein] which results in decreased susceptibility to Methamphetamine, Mianserin binds to and results in decreased activity of HTR2C protein CTD PMID:10978843 , PMID:15213358 mirtazapine increases expression ISO RGD:736842 6480464 mirtazapine results in increased expression of HTR2C protein CTD PMID:18083778 mirtazapine multiple interactions ISO RGD:736842 6480464 6-chloro-5-methyl-1-((2-(2-methylpyrid-3-yloxy)pyrid-5-yl)carbamoyl)indoline inhibits the reaction [mirtazapine results in increased expression of HTR2C protein], mirtazapine binds to and affects the activity of HTR2C protein CTD PMID:18083778 nefazodone affects binding ISO RGD:736842 6480464 nefazodone binds to HTR2C protein CTD PMID:18083778 nitrates decreases expression ISO RGD:2848 6480464 Nitrates results in decreased expression of HTR2C mRNA CTD PMID:30022042 nortriptyline decreases expression ISO RGD:736842 6480464 Nortriptyline results in decreased expression of HTR2C protein CTD PMID:8131152 olanzapine increases response to substance ISO RGD:736842 6480464 HTR2C gene polymorphism results in increased susceptibility to olanzapine CTD PMID:19434072 olanzapine affects binding EXP 6480464 olanzapine binds to HTR2C protein CTD PMID:24389121 olanzapine affects binding ISO RGD:736842 6480464 olanzapine binds to HTR2C protein CTD PMID:16983399 olanzapine affects response to substance ISO RGD:736842 6480464 HTR2C gene polymorphism affects the susceptibility to olanzapine more ... CTD PMID:15666332 more ... paraquat decreases expression ISO RGD:2848 6480464 Paraquat results in decreased expression of HTR2C mRNA CTD PMID:32680482 paroxetine multiple interactions EXP 6480464 [[Paroxetine binds to and results in increased activity of HTR2C protein] which results in increased phosphorylation of and results in increased activity of EGFR protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein more ... CTD PMID:19662385 PCB138 multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 phenylmercury acetate decreases expression ISO RGD:736842 6480464 Phenylmercuric Acetate results in decreased expression of HTR2C mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:736842 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of HTR2C mRNA CTD PMID:27188386 potassium dichromate increases expression EXP 6480464 Potassium Dichromate results in increased expression of HTR2C mRNA CTD PMID:23608068 risperidone affects response to substance ISO RGD:736842 6480464 HTR2C gene polymorphism affects the susceptibility to Risperidone, HTR2C protein affects the susceptibility to Risperidone CTD PMID:19142101 risperidone multiple interactions ISO RGD:736842 6480464 HTR2C gene polymorphism affects the reaction [Risperidone results in increased expression of PRL protein] CTD PMID:19997080 risperidone increases response to substance ISO RGD:736842 6480464 HTR2C protein results in increased susceptibility to Risperidone CTD PMID:19997080 sarpogrelate affects binding ISO RGD:736842 6480464 sarpogrelate binds to HTR2C protein CTD PMID:16880620 SB 206553 increases expression ISO RGD:736842 6480464 SB 206553 results in increased expression of HTR2C protein CTD PMID:18083778 SB 206553 multiple interactions ISO RGD:2848 6480464 SB 206553 binds to and results in decreased activity of HTR2C protein CTD PMID:16521035 SB 243213 multiple interactions ISO RGD:736842 6480464 SB 243213 binds to and results in decreased activity of HTR2C protein CTD PMID:11489455 SB 431542 multiple interactions ISO RGD:736842 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of HTR2C mRNA CTD PMID:27188386 scopolamine increases expression ISO RGD:2848 6480464 Scopolamine results in increased expression of HTR2C mRNA CTD PMID:17540011 serotonin affects expression EXP 6480464 Serotonin affects the expression of HTR2C mRNA CTD PMID:21083617 serotonin multiple interactions ISO RGD:2848 6480464 [Fluoxetine results in increased abundance of Serotonin] which results in decreased expression of HTR2C mRNA more ... CTD PMID:21554931 , PMID:9050900 sertraline multiple interactions ISO RGD:2848 6480464 [Estradiol co-treated with Sertraline] affects the expression of HTR2C mRNA, Estradiol promotes the reaction [Sertraline results in increased expression of HTR2C mRNA] CTD PMID:18650020 sertraline increases expression ISO RGD:2848 6480464 Sertraline results in increased expression of HTR2C mRNA CTD PMID:18650020 silicon dioxide increases expression ISO RGD:2848 6480464 Silicon Dioxide results in increased expression of HTR2C mRNA CTD PMID:32721576 streptozocin multiple interactions EXP 6480464 [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of HTR2C mRNA CTD PMID:33484791 testosterone decreases expression ISO RGD:736842 6480464 Testosterone results in decreased expression of HTR2C mRNA CTD PMID:21592394 testosterone multiple interactions ISO RGD:2848 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in decreased expression of HTR2C mRNA CTD PMID:32741896 testosterone multiple interactions ISO RGD:736842 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of HTR2C mRNA CTD PMID:21592394 thimerosal increases expression ISO RGD:736842 6480464 Thimerosal results in increased expression of HTR2C mRNA CTD PMID:27188386 titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of HTR2C mRNA CTD PMID:23557971 trazodone affects binding ISO RGD:736842 6480464 Trazodone binds to HTR2C protein CTD PMID:18083778 trichostatin A increases expression ISO RGD:736842 6480464 trichostatin A results in increased expression of HTR2C mRNA CTD PMID:24935251 valproic acid decreases expression ISO RGD:736842 6480464 Valproic Acid results in decreased expression of HTR2C mRNA CTD PMID:23179753 valproic acid increases expression ISO RGD:736842 6480464 Valproic Acid results in increased expression of HTR2C mRNA CTD PMID:24935251 , PMID:28001369 valproic acid affects expression ISO RGD:736842 6480464 Valproic Acid affects the expression of HTR2C mRNA CTD PMID:25979313 vorinostat decreases expression ISO RGD:736842 6480464 vorinostat results in decreased expression of HTR2C mRNA CTD PMID:27188386
