Htr2c (5-hydroxytryptamine (serotonin) receptor 2C) - Rat Genome Database

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Gene: Htr2c (5-hydroxytryptamine (serotonin) receptor 2C) Mus musculus
Analyze
Symbol: Htr2c
Name: 5-hydroxytryptamine (serotonin) receptor 2C
RGD ID: 10748
MGI Page MGI
Description: Enables G protein-coupled serotonin receptor activity. Involved in several processes, including behavioral fear response; phospholipase C-activating G protein-coupled receptor signaling pathway; and regulation of corticotropin-releasing hormone secretion. Acts upstream of or within positive regulation of fat cell differentiation. Predicted to be located in external side of plasma membrane. Predicted to be part of G protein-coupled serotonin receptor complex. Predicted to be active in dendrite. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; brain; branchial arch mesenchyme; heart; and sensory organ. Used to study Prader-Willi syndrome and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in bipolar disorder; obesity; and schizophrenia. Orthologous to human HTR2C (5-hydroxytryptamine receptor 2C).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5-HT-1C; 5-HT-2C; 5-HT1C; 5-HT2C; 5-HT2C receptor; 5-HT2cR; 5-HTR2C; 5-hydroxytryptamine receptor 1C; 5-hydroxytryptamine receptor 2C; 5HT1c; Htr1; Htr1c; S; serotonin receptor 2C; SR1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X145,745,509 - 145,980,273 (+)NCBIGRCm39mm39
GRCm39 EnsemblX145,745,509 - 145,980,273 (+)Ensembl
GRCm38X146,962,464 - 147,197,277 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX146,962,513 - 147,197,277 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X143,397,056 - 143,631,820 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X142,208,881 - 142,443,644 (+)NCBImm8
CeleraX130,902,904 - 131,136,225 (+)NCBICelera
Cytogenetic MapXF2NCBI
cM MapX68.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
1,2-dichloroethane  (EXP)
1-(3-chlorophenyl)piperazine  (EXP)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
1-bromopropane  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine  (ISO)
2-chloro-6-(1-piperazinyl)pyrazine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (ISO)
agomelatine  (ISO)
all-trans-retinoic acid  (ISO)
amitriptyline  (ISO)
ammonium chloride  (ISO)
aripiprazole  (ISO)
arsenite(3-)  (EXP,ISO)
atrazine  (ISO)
Bardoxolone methyl  (ISO)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (ISO)
bisphenol F  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
chlorpyrifos  (ISO)
citalopram  (ISO)
clomipramine  (ISO)
clozapine  (ISO)
cocaine  (EXP,ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP,ISO)
dieldrin  (ISO)
dioxygen  (ISO)
dopamine  (EXP)
dorsomorphin  (ISO)
entinostat  (ISO)
ethanol  (EXP)
fenfluramine  (ISO)
fenvalerate  (ISO)
fluoxetine  (EXP,ISO)
fluphenazine  (ISO)
folic acid  (EXP)
genistein  (ISO)
haloperidol  (ISO)
imidacloprid  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (EXP,ISO)
loxapine  (ISO)
mesulergine  (ISO)
methamphetamine  (EXP,ISO)
methoxychlor  (ISO)
mianserin  (EXP,ISO)
mirtazapine  (ISO)
nefazodone  (ISO)
nitrates  (ISO)
nortriptyline  (ISO)
olanzapine  (EXP,ISO)
paraquat  (ISO)
paroxetine  (EXP)
PCB138  (EXP)
phenylmercury acetate  (ISO)
potassium dichromate  (EXP)
risperidone  (ISO)
sarpogrelate  (ISO)
SB 206553  (ISO)
SB 243213  (ISO)
SB 431542  (ISO)
scopolamine  (ISO)
serotonin  (EXP,ISO)
sertraline  (ISO)
silicon dioxide  (ISO)
streptozocin  (EXP)
testosterone  (ISO)
thimerosal  (ISO)
titanium dioxide  (EXP)
trazodone  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ regeneration  (ISO)
behavioral fear response  (IMP)
behavioral response to nicotine  (ISO)
cellular calcium ion homeostasis  (ISO)
cGMP-mediated signaling  (ISO)
chemical synaptic transmission  (IBA)
feeding behavior  (IMP,ISO)
G protein-coupled receptor signaling pathway  (IEA)
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  (IBA)
G protein-coupled serotonin receptor signaling pathway  (ISO)
inositol phosphate-mediated signaling  (ISO)
locomotory behavior  (IEA)
negative regulation of dopamine metabolic process  (ISO)
negative regulation of locomotion  (ISO)
phospholipase C-activating G protein-coupled receptor signaling pathway  (IBA)
phospholipase C-activating serotonin receptor signaling pathway  (IMP,ISO)
phospholipase D-activating G protein-coupled receptor signaling pathway  (ISO)
positive regulation of acetylcholine secretion, neurotransmission  (ISO)
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway  (IMP)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of fat cell differentiation  (IMP)
positive regulation of gamma-aminobutyric acid secretion  (ISO)
positive regulation of phosphatidylinositol biosynthetic process  (ISO)
positive regulation of vasoconstriction  (ISO)
regulation of appetite  (IMP)
regulation of corticotropin-releasing hormone secretion  (IMP)
regulation of nervous system process  (IMP)
regulation of sensory perception of pain  (ISO)
release of sequestered calcium ion into cytosol  (IBA,ISO)
response to xenobiotic stimulus  (IBA,ISO)
signal transduction  (IEA)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal body temperature  (IAGP)
abnormal locomotor activation  (IAGP)
abnormal metabolism  (IAGP)
abnormal nervous system electrophysiology  (IAGP)
abnormal pilomotor reflex  (IAGP)
abnormal respiratory quotient  (IAGP)
abnormal response to new environment  (IAGP)
abnormal response/metabolism to endogenous compounds  (IAGP)
abnormal spatial learning  (IAGP)
abnormal tumor necrosis factor level  (IAGP)
decreased body fat mass  (IAGP)
decreased body length  (IAGP)
decreased body mass index  (IAGP)
decreased body weight  (IAGP)
decreased brown adipose tissue mass  (IAGP)
decreased circulating cholesterol level  (IAGP)
decreased circulating glucose level  (IAGP)
decreased circulating insulin level  (IAGP)
decreased circulating insulin-like growth factor I level  (IAGP)
decreased circulating leptin level  (IAGP)
decreased circulating triglyceride level  (IAGP)
decreased food intake  (IAGP)
decreased grip strength  (IAGP)
decreased lean body mass  (IAGP)
decreased oxygen consumption  (IAGP)
decreased white adipose tissue amount  (IAGP)
dehydration  (IAGP)
enhanced behavioral response to xenobiotic  (IAGP)
hunched posture  (IAGP)
hyperactivity  (IAGP)
hyperglycemia  (IAGP)
hypoactivity  (IAGP)
hypotonia  (IAGP)
impaired behavioral response to xenobiotic  (IAGP)
impaired coordination  (IAGP)
impaired glucose tolerance  (IAGP)
impaired passive avoidance behavior  (IAGP)
increased basal metabolism  (IAGP)
increased body weight  (IAGP)
increased circulating corticosterone level  (IAGP)
increased circulating ghrelin level  (IAGP)
increased circulating glucagon level  (IAGP)
increased circulating glucose level  (IAGP)
increased circulating growth hormone level  (IAGP)
increased circulating insulin level  (IAGP)
increased circulating leptin level  (IAGP)
increased coping response  (IAGP)
increased energy expenditure  (IAGP)
increased epididymal fat pad weight  (IAGP)
increased food intake  (IAGP)
increased grooming behavior  (IAGP)
increased oxygen consumption  (IAGP)
increased percent body fat/body weight  (IAGP)
increased physiological sensitivity to xenobiotic  (IAGP)
increased renal fat pad weight  (IAGP)
increased sensitivity to xenobiotic induced morbidity/mortality  (IAGP)
increased susceptibility to age related obesity  (IAGP)
increased susceptibility to diet-induced obesity  (IAGP)
increased susceptibility to pharmacologically induced seizures  (IAGP)
increased white adipose tissue amount  (IAGP)
insulin resistance  (IAGP)
lethality at weaning, incomplete penetrance  (IAGP)
mottled coat  (IAGP)
polyphagia  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
reduced long term potentiation  (IAGP)
seizures  (IAGP)
slow postnatal weight gain  (IAGP)
sporadic seizures  (IAGP)
tonic seizures  (IAGP)
tonic-clonic seizures  (IAGP)
References

Additional References at PubMed
PMID:1302605   PMID:1373499   PMID:1381232   PMID:1426253   PMID:1661811   PMID:3473504   PMID:7582481   PMID:7700379   PMID:8626761   PMID:8833759   PMID:9153397   PMID:9165122  
PMID:9241279   PMID:9457670   PMID:9730605   PMID:9771748   PMID:9844009   PMID:9878187   PMID:10023077   PMID:10349636   PMID:10352232   PMID:10353435   PMID:10501973   PMID:10514821  
PMID:10627607   PMID:10751458   PMID:10767319   PMID:10799679   PMID:10978843   PMID:11042159   PMID:11076861   PMID:11089532   PMID:11106375   PMID:11217851   PMID:11387227   PMID:11754082  
PMID:12097814   PMID:12150939   PMID:12427861   PMID:12431861   PMID:12477932   PMID:12486144   PMID:12534984   PMID:12540602   PMID:12614326   PMID:12678665   PMID:12682077   PMID:12782219  
PMID:12834793   PMID:14988405   PMID:15659601   PMID:16141072   PMID:16141073   PMID:16256085   PMID:16602821   PMID:16904273   PMID:16973729   PMID:17064660   PMID:17287521   PMID:17307311  
PMID:17360519   PMID:17367945   PMID:17451451   PMID:17561825   PMID:17596444   PMID:17620091   PMID:17677002   PMID:18039773   PMID:18039786   PMID:18256173   PMID:18262506   PMID:18477467  
PMID:18495184   PMID:18719666   PMID:19005016   PMID:19008301   PMID:19036977   PMID:19038216   PMID:19304781   PMID:19322172   PMID:19420382   PMID:19473847   PMID:19501602   PMID:19523439  
PMID:19553455   PMID:19737523   PMID:20165943   PMID:20181818   PMID:20394819   PMID:20495077   PMID:20582266   PMID:20624407   PMID:20651031   PMID:20668550   PMID:20719859   PMID:20952540  
PMID:21037584   PMID:21048120   PMID:21118683   PMID:21267068   PMID:21281651   PMID:21340474   PMID:21473759   PMID:21756875   PMID:21835345   PMID:21873635   PMID:22569571   PMID:22640814  
PMID:22800924   PMID:23192316   PMID:23247076   PMID:23303047   PMID:23349838   PMID:23933143   PMID:24177424   PMID:24204954   PMID:24345557   PMID:24733892   PMID:24952961   PMID:25229718  
PMID:25257581   PMID:25727097   PMID:25732068   PMID:25784603   PMID:26053401   PMID:26066076   PMID:26248536   PMID:26308619   PMID:26527397   PMID:26630489   PMID:26977396   PMID:26999672  
PMID:27516377   PMID:27556938   PMID:27568567   PMID:27693255   PMID:27882999   PMID:27931246   PMID:27934886   PMID:28031476   PMID:28186389   PMID:28258217   PMID:28664341   PMID:28805659  
PMID:28851741   PMID:29541541   PMID:29548885   PMID:29572515   PMID:29914853   PMID:29969651   PMID:30056125   PMID:30097291   PMID:30104733   PMID:30146485   PMID:30792491   PMID:31299228  
PMID:31415146   PMID:31489921   PMID:31786274   PMID:31959933   PMID:32961128   PMID:33016258   PMID:33156577  


Genomics

Comparative Map Data
Htr2c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X145,745,509 - 145,980,273 (+)NCBIGRCm39mm39
GRCm39 EnsemblX145,745,509 - 145,980,273 (+)Ensembl
GRCm38X146,962,464 - 147,197,277 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX146,962,513 - 147,197,277 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X143,397,056 - 143,631,820 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X142,208,881 - 142,443,644 (+)NCBImm8
CeleraX130,902,904 - 131,136,225 (+)NCBICelera
Cytogenetic MapXF2NCBI
cM MapX68.46NCBI
HTR2C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX114,584,078 - 114,910,061 (+)EnsemblGRCh38hg38GRCh38
GRCh38X114,584,086 - 114,910,061 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X113,818,551 - 114,144,624 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X113,724,807 - 114,050,880 (+)NCBINCBI36hg18NCBI36
Build 34X113,641,530 - 113,967,604NCBI
CeleraX114,253,715 - 114,579,778 (+)NCBI
Cytogenetic MapXq23NCBI
HuRefX103,403,272 - 103,731,741 (+)NCBIHuRef
CHM1_1X113,729,484 - 114,055,500 (+)NCBICHM1_1
Htr2c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X110,640,777 - 110,870,288 (+)NCBImRatBN7.2
mRatBN7.2 EnsemblX110,641,153 - 110,870,287 (+)Ensembl
Rnor_6.0X118,084,520 - 118,318,040 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX118,084,890 - 118,318,039 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X118,226,113 - 118,460,830 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X31,012,921 - 31,244,127 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X31,069,048 - 31,185,684 (-)NCBI
CeleraX109,958,913 - 110,179,824 (+)NCBICelera
Cytogenetic MapXq34NCBI
Htr2c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955490910,415 - 1,126,373 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955490912,615 - 1,126,347 (-)NCBIChiLan1.0ChiLan1.0
HTR2C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X114,169,823 - 114,503,179 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX114,199,485 - 114,503,201 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X103,673,172 - 103,999,133 (+)NCBIMhudiblu_PPA_v0panPan3
HTR2C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X87,342,800 - 87,641,224 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX87,342,792 - 87,638,579 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX73,595,073 - 73,759,737 (+)NCBI
ROS_Cfam_1.0X89,055,367 - 89,357,473 (+)NCBI
UMICH_Zoey_3.1X86,633,342 - 86,797,977 (+)NCBI
UNSW_CanFamBas_1.0X88,307,583 - 88,472,268 (+)NCBI
UU_Cfam_GSD_1.0X88,140,047 - 88,305,373 (+)NCBI
Htr2c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X86,426,392 - 86,655,882 (+)NCBI
SpeTri2.0NW_0049364991,002,083 - 1,109,446 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HTR2C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX94,053,456 - 94,313,356 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X94,053,415 - 94,313,352 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X108,811,549 - 108,871,722 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2X108,566,657 - 108,733,261 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HTR2C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X102,190,355 - 102,499,928 (+)NCBI
ChlSab1.1 EnsemblX102,325,731 - 102,497,278 (+)Ensembl
Vero_WHO_p1.0NW_02366606527,537,759 - 27,837,340 (+)NCBI
Htr2c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249401,040,744 - 1,299,266 (-)NCBI

Position Markers
X72230  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X147,195,134 - 147,195,248UniSTSGRCm38
MGSCv37X143,629,677 - 143,629,791UniSTSGRCm37
CeleraX131,134,082 - 131,134,196UniSTS
Cytogenetic MapXD-F4UniSTS
Whitehead/MRC_RHX1681.01UniSTS
G67051  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X147,072,526 - 147,073,033UniSTSGRCm38
MGSCv37X143,507,069 - 143,507,576UniSTSGRCm37
CeleraX131,012,822 - 131,013,329UniSTS
Cytogenetic MapXD-F4UniSTS
30.MMHAP67FLB6.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X147,183,798 - 147,183,950UniSTSGRCm38
MGSCv37X143,618,341 - 143,618,493UniSTSGRCm37
CeleraX131,122,691 - 131,122,843UniSTS
Cytogenetic MapXD-F4UniSTS
Whitehead_YACX UniSTS
PMC166422P3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X147,193,938 - 147,194,237UniSTSGRCm38
MGSCv37X143,628,481 - 143,628,780UniSTSGRCm37
CeleraX131,132,887 - 131,133,186UniSTS
Cytogenetic MapXD-F4UniSTS
BB315810  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X147,197,107 - 147,197,194UniSTSGRCm38
MGSCv37X143,631,650 - 143,631,737UniSTSGRCm37
CeleraX131,136,055 - 131,136,142UniSTS
Cytogenetic MapXD-F4UniSTS
Whitehead/MRC_RH91128.43UniSTS
Htr2c  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapXD-F4UniSTS
cM MapX66.15UniSTS
Htr2c  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X147,195,453 - 147,195,568UniSTSGRCm38
MGSCv37X143,629,996 - 143,630,111UniSTSGRCm37
CeleraX131,134,401 - 131,134,516UniSTS
Cytogenetic MapXD-F4UniSTS
cM MapX66.15UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302000Pgia25_mproteoglycan induced arthritis 2 (mouse)Not determinedX145691384171031299Mouse
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7360056151324042Mouse
1301209Cia19_mcollagen induced arthritis 19 (mouse)Not determinedX122083468161430042Mouse
1357823Spha3_msperm head anomaly 3 (mouse)Not determinedX103012242163975945Mouse
1301276Tswt_mtestis weight (mouse)Not determinedX139475662152006342Mouse
1558900Bw3_mbody weight QTL 3 (mouse)Not determinedX134639291166515599Mouse
10401118Pgia39_mproteoglycan induced arthritis 39 (mouse)Not determinedX145691384171031299Mouse
10412164Cmv2_mcytomegalovirus resistance 2 (mouse)Not determinedX126902153160902273Mouse
25314309Syncl5_msynaptonemal complex length 5 (mouse)X123000000153800000Mouse
13824980Ferq1_mgenetic fertility QTL 1 (mouse)X55000000150000000Mouse
13208556Lgth14_mbody length 14 (mouse)X95000000151000000Mouse
13208552Wght12_mweight 12 (mouse)X95000000151000000Mouse
13824981Svwq2_mseminal vesicle weight QTL 2 (mouse)X130000000155000000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3546
Count of miRNA genes:779
Interacting mature miRNAs:1019
Transcripts:ENSMUST00000036303, ENSMUST00000096299, ENSMUST00000112831, ENSMUST00000131999, ENSMUST00000134368, ENSMUST00000149260, ENSMUST00000156697
Prediction methods:Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000036303   ⟹   ENSMUSP00000043936
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX145,745,509 - 145,980,270 (+)Ensembl
GRCm38.p6 EnsemblX146,962,513 - 147,197,274 (+)Ensembl
RefSeq Acc Id: ENSMUST00000096299   ⟹   ENSMUSP00000094021
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX145,745,510 - 145,980,273 (+)Ensembl
GRCm38.p6 EnsemblX146,962,514 - 147,197,277 (+)Ensembl
RefSeq Acc Id: ENSMUST00000112831   ⟹   ENSMUSP00000108450
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX145,746,019 - 145,966,148 (+)Ensembl
GRCm38.p6 EnsemblX146,963,023 - 147,183,152 (+)Ensembl
RefSeq Acc Id: ENSMUST00000131999
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX145,745,509 - 145,861,060 (+)Ensembl
GRCm38.p6 EnsemblX146,962,513 - 147,078,064 (+)Ensembl
RefSeq Acc Id: ENSMUST00000134368
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX145,745,626 - 145,855,525 (+)Ensembl
GRCm38.p6 EnsemblX146,962,630 - 147,072,529 (+)Ensembl
RefSeq Acc Id: ENSMUST00000149260
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX145,745,509 - 145,772,324 (+)Ensembl
GRCm38.p6 EnsemblX146,962,513 - 146,989,328 (+)Ensembl
RefSeq Acc Id: ENSMUST00000156697   ⟹   ENSMUSP00000138772
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX145,745,510 - 145,980,273 (+)Ensembl
GRCm38.p6 EnsemblX146,962,514 - 147,197,277 (+)Ensembl
RefSeq Acc Id: NM_008312   ⟹   NP_032338
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X145,745,509 - 145,980,273 (+)NCBI
GRCm38X146,962,513 - 147,197,277 (+)ENTREZGENE
MGSCv37X143,397,056 - 143,631,820 (+)RGD
CeleraX130,902,904 - 131,136,225 (+)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030251228   ⟹   XP_030107088
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X145,745,509 - 145,980,273 (+)NCBI
GRCm38X146,962,464 - 147,197,277 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032338   ⟸   NM_008312
- Peptide Label: precursor
- UniProtKB: P34968 (UniProtKB/Swiss-Prot),   Q8BZI5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030107088   ⟸   XM_030251228
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000108450   ⟸   ENSMUST00000112831
RefSeq Acc Id: ENSMUSP00000043936   ⟸   ENSMUST00000036303
RefSeq Acc Id: ENSMUSP00000138772   ⟸   ENSMUST00000156697
RefSeq Acc Id: ENSMUSP00000094021   ⟸   ENSMUST00000096299
Protein Domains
G_PROTEIN_RECEP_F1_2

Promoters
RGD ID:6845840
Promoter ID:MM_KWN:62200
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:NM_008312,   OTTMUST00000045549,   OTTMUST00000045550,   OTTMUST00000045551,   OTTMUST00000045552,   OTTMUST00000045553,   UC009UNE.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X143,396,861 - 143,397,361 (+)MPROMDB
RGD ID:13681582
Promoter ID:EPDNEW_M24940
Type:multiple initiation site
Name:Htr2c_1
Description:Mus musculus 5-hydroxytryptamine receptor 2C , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M24941  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X146,962,513 - 146,962,573EPDNEW
RGD ID:13681584
Promoter ID:EPDNEW_M24941
Type:multiple initiation site
Name:Htr2c_2
Description:Mus musculus 5-hydroxytryptamine receptor 2C , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M24940  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X147,019,954 - 147,020,014EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96281 AgrOrtholog
Ensembl Genes ENSMUSG00000041380 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000043936 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000094021 UniProtKB/Swiss-Prot
  ENSMUSP00000108450 UniProtKB/TrEMBL
  ENSMUSP00000138772 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000036303 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000096299 UniProtKB/Swiss-Prot
  ENSMUST00000112831 UniProtKB/TrEMBL
  ENSMUST00000156697 UniProtKB/TrEMBL
InterPro 5HT2C_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  5HT_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15560 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:96281 ENTREZGENE
NCBI Gene 15560 ENTREZGENE
PANTHER PTHR24247:SF32 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB HTR2C RGD
PhenoGen Htr2c PhenoGen
PRINTS 5HT2CRECEPTR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  5HTRECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt 5HT2C_MOUSE UniProtKB/Swiss-Prot
  B1ATN4_MOUSE UniProtKB/TrEMBL
  B2RUD4_MOUSE UniProtKB/TrEMBL
  P34968 ENTREZGENE
  Q8BZI5 ENTREZGENE, UniProtKB/TrEMBL
  S4R2T0_MOUSE UniProtKB/TrEMBL
UniProt Secondary B1ATN5 UniProtKB/Swiss-Prot
  Q5WRU6 UniProtKB/Swiss-Prot