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Gene: Stxbp1 (syntaxin binding protein 1) Mus musculus
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Symbol: Stxbp1
Name: syntaxin binding protein 1
Description: Exhibits syntaxin-1 binding activity. Involved in several processes, including axon target recognition; exocytosis; and negative regulation of synaptic transmission. Localizes to several cellular components, including glutamatergic synapse; phagocytic vesicle; and presynaptic active zone membrane. Is expressed in nervous system and sensory organ. Human ortholog(s) of this gene implicated in West syndrome and early infantile epileptic encephalopathy 4. Orthologous to human STXBP1 (syntaxin binding protein 1); PARTICIPATES IN insulin secretion pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetohydrazide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI317162; AI326233; minisatellite 10g detected by probe MMS10; MMS10-G; Ms10g; Munc-18a; Munc18-1; N-sec1; nsec1; protein unc-18 homolog 1; protein unc-18 homolog A; Rb-sec1; Sxtbp1; syntaxin-binding protein 1; UNC-18 homolog; unc-18-1; unc-18A; Unc18-1; Unc18h
Orthologs:
Homo sapiens (human) : STXBP1 (syntaxin binding protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Stxbp1 (syntaxin binding protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Stxbp1 (syntaxin binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : STXBP1 (syntaxin binding protein 1)
Canis lupus familiaris (dog) : STXBP1 (syntaxin binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stxbp1 (syntaxin binding protein 1)
Sus scrofa (pig) : STXBP1 (syntaxin binding protein 1)
Chlorocebus sabaeus (African green monkey) : STXBP1 (syntaxin binding protein 1)
Heterocephalus glaber (naked mole-rat) : Stxbp1 (syntaxin binding protein 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl232,787,602 - 32,847,245 (-)EnsemblGRCm38mm10GRCm38
GRCm38232,787,607 - 32,847,237 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37232,643,127 - 32,702,757 (-)NCBIGRCm37mm9NCBIm37
MGSCv36232,609,971 - 32,669,135 (-)NCBImm8
Celera232,494,462 - 32,554,183 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Stxbp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11361
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.