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Gene: Gnai2 (guanine nucleotide binding protein (G protein), alpha inhibiting 2) Mus musculus
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Symbol: Gnai2
Name: guanine nucleotide binding protein (G protein), alpha inhibiting 2
Description: ENCODES a protein that exhibits GTP binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; cell population proliferation; G protein-coupled acetylcholine receptor signaling pathway; PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphai protein family; angiotensin II signaling pathway via AT2 receptor; dopamine signaling pathway via D2 family of receptors; ASSOCIATED WITH abnormal cellular extravasation; abnormal colon morphology; abnormal cytokine level; ASSOCIATED WITH ACTH-secreting pituitary adenoma (ortholog); Adrenal Cortex Neoplasms (ortholog); Animal Mammary Neoplasms (ortholog); FOUND IN cell body; dendrite; centrosome (ortholog); INTERACTS WITH (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3',5'-cyclic AMP
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adenylate cyclase-inhibiting G alpha protein; C76432; Galphai2; Gia; Gnai-2; guanine nucleotide binding protein, alpha inhibiting 2; guanine nucleotide-binding protein G(i) subunit alpha-2
Orthologs:
Homo sapiens (human) : GNAI2 (G protein subunit alpha i2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gnai2 (G protein subunit alpha i2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnai2 (G protein subunit alpha i2)
Pan paniscus (bonobo/pygmy chimpanzee) : GNAI2 (G protein subunit alpha i2)
Canis lupus familiaris (dog) : GNAI2 (G protein subunit alpha i2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnai2 (G protein subunit alpha i2)
Sus scrofa (pig) : GNAI2 (G protein subunit alpha i2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389107,614,125 - 107,635,391 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379107,516,469 - 107,537,673 (-)NCBIGRCm37mm9NCBIm37
MGSCv369107,472,714 - 107,493,430 (-)NCBImm8
Celera9114,146,679 - 114,147,485 (+)NCBICelera
Celera9107,222,922 - 107,240,939 (-)NCBICelera
Cytogenetic Map9 F1NCBI
cM Map958.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gnai2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730994
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.