Gnai2 (G protein subunit alpha i2) - Rat Genome Database

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Gene: Gnai2 (G protein subunit alpha i2) Mus musculus
Analyze
Symbol: Gnai2
Name: G protein subunit alpha i2
RGD ID: 730994
MGI Page MGI
Description: Predicted to enable several functions, including G-protein beta/gamma-subunit complex binding activity; GTP binding activity; and GTPase activity. Involved in modulation of chemical synaptic transmission. Acts upstream of or within G protein-coupled acetylcholine receptor signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; and cell population proliferation. Located in cell body and dendrite. Is active in hippocampal mossy fiber to CA3 synapse and neuronal dense core vesicle. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study inflammatory bowel disease 12. Orthologous to human GNAI2 (G protein subunit alpha i2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: adenylate cyclase-inhibiting G alpha protein; C76432; G; Gal; Galphai2; Gia; Gna; Gnai-2; guanine nucleotide binding protein (G protein), alpha inhibiting 2; guanine nucleotide binding protein, alpha inhibiting 2; guanine nucleotide-binding protein G(i) subunit alpha-2; heterotrimeric guanine nucleotide-binding protein 1c; Hg1c
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399107,491,324 - 107,512,542 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9107,491,324 - 107,512,566 (-)EnsemblGRCm39 Ensembl
GRCm389107,614,125 - 107,635,391 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9107,614,125 - 107,635,367 (-)EnsemblGRCm38mm10GRCm38
MGSCv379107,516,469 - 107,537,673 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369107,472,714 - 107,493,430 (-)NCBIMGSCv36mm8
Celera9107,222,922 - 107,240,939 (-)NCBICelera
Cytogenetic Map9F1NCBI
cM Map958.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-nicotine  (EXP,ISO)
1,2-dimethylhydrazine  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3',5'-cyclic AMP  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (ISO)
8-Br-cAMP  (ISO)
acetamide  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
amino acid  (EXP)
amitrole  (ISO)
antimycin A  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
caffeine  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
cannabidiol  (EXP)
cannabigerol  (EXP)
captan  (EXP)
CGP 52608  (ISO)
chlordecone  (EXP)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clozapine  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
corticosterone  (EXP)
CU-O LINKAGE  (EXP)
cyclosporin A  (ISO)
D-glucose  (EXP,ISO)
deguelin  (ISO)
dexamethasone  (EXP,ISO)
diazinon  (ISO)
dibenziodolium  (ISO)
dichlorine  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
diphenhydramine  (EXP)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
ethanol  (EXP,ISO)
fenpyroximate  (ISO)
fenthion  (EXP)
flavonoids  (ISO)
fluoxetine  (EXP,ISO)
folic acid  (EXP)
folpet  (EXP)
fumonisin B1  (EXP)
glafenine  (ISO)
glucose  (EXP,ISO)
haloperidol  (ISO)
hydrogen cyanide  (EXP)
ivermectin  (ISO)
lipopolysaccharide  (EXP)
malathion  (ISO)
methidathion  (EXP)
methimazole  (ISO)
methotrexate  (EXP)
morphine  (EXP,ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
nefazodone  (ISO)
nicotine  (EXP,ISO)
nitroprusside  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
ozone  (ISO)
paracetamol  (ISO)
pentachlorophenol  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
peroxynitrous acid  (ISO)
phenobarbital  (EXP)
PhIP  (ISO)
picoxystrobin  (ISO)
picrotoxin  (ISO)
propiconazole  (ISO)
propofol  (ISO)
pyrimidifen  (ISO)
quercetin  (ISO)
reactive oxygen species  (EXP)
reserpine  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
S-nitroso-N-acetyl-D-penicillamine  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (ISO)
Soman  (ISO)
streptozocin  (ISO)
succimer  (EXP)
sulfadimethoxine  (ISO)
sunitinib  (ISO)
tebufenpyrad  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP)
theophylline  (ISO)
thifluzamide  (ISO)
thioacetamide  (ISO)
tipifarnib  (ISO)
toluene  (ISO)
topiramate  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adenylate cyclase-activating G protein-coupled receptor signaling pathway  (ISO)
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway  (IBA,IMP,ISA)
adenylate cyclase-modulating G protein-coupled receptor signaling pathway  (IEA)
cell division  (ISO)
cell population proliferation  (IPI)
G protein-coupled acetylcholine receptor signaling pathway  (IMP)
G protein-coupled adenosine receptor signaling pathway  (IBA,ISO)
G protein-coupled glutamate receptor signaling pathway  (ISO)
G protein-coupled receptor signaling pathway  (ISO)
gamma-aminobutyric acid signaling pathway  (IBA,ISO)
modulation of chemical synaptic transmission  (IDA,IMP)
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway  (ISO)
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process  (ISO)
negative regulation of apoptotic signaling pathway  (ISO)
negative regulation of calcium ion-dependent exocytosis  (ISO)
negative regulation of protein tyrosine phosphatase activity  (ISO)
negative regulation of synaptic transmission  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of insulin receptor signaling pathway  (ISO)
positive regulation of NAD(P)H oxidase activity  (ISO)
positive regulation of neural precursor cell proliferation  (ISO)
positive regulation of superoxide anion generation  (ISO)
positive regulation of urine volume  (ISO)
positive regulation of vascular associated smooth muscle cell proliferation  (ISO)
regulation of calcium ion transport  (ISO)
regulation of heart contraction  (IMP)
signal transduction  (IEA)

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cellular extravasation  (IAGP)
abnormal colon morphology  (IAGP)
abnormal cytokine level  (IAGP)
abnormal cytokine secretion  (IAGP)
abnormal digestive system physiology  (IAGP)
abnormal eosinophil physiology  (IAGP)
abnormal immune system morphology  (IAGP)
abnormal immune system physiology  (IAGP)
abnormal large intestine crypts of Lieberkuhn morphology  (IAGP)
abnormal large intestine morphology  (IAGP)
abnormal leukocyte adhesion  (IAGP)
abnormal leukocyte cell number  (IAGP)
abnormal liver morphology  (IAGP)
abnormal neutrophil physiology  (IAGP)
abnormal response to cardiac infarction  (IAGP)
abnormal response/metabolism to endogenous compounds  (IAGP)
abnormal sternocostal joint morphology  (IAGP)
abnormal T cell physiology  (IAGP)
ascites  (IAGP)
chronic diarrhea  (IAGP)
colitis  (IAGP)
cyanosis  (IAGP)
decreased birth body size  (IAGP)
decreased body weight  (IAGP)
decreased eosinophil cell number  (IAGP)
decreased heart rate  (IAGP)
decreased myocardial infarct size  (IAGP)
decreased physiological sensitivity to xenobiotic  (IAGP)
decreased T-helper 17 cell number  (IAGP)
dilated heart  (IAGP)
embryonic lethality, incomplete penetrance  (IAGP)
fatigue  (IAGP)
increased circulating interferon-gamma level  (IAGP)
increased circulating interleukin-4 level  (IAGP)
increased circulating interleukin-5 level  (IAGP)
increased eosinophil cell number  (IAGP)
increased granulocyte number  (IAGP)
increased heart rate  (IAGP)
increased heart weight  (IAGP)
increased IgA level  (IAGP)
increased IgG level  (IAGP)
increased IgM level  (IAGP)
increased immunoglobulin level  (IAGP)
increased incidence of tumors by chemical induction  (IAGP)
increased inflammatory response  (IAGP)
increased interferon-gamma secretion  (IAGP)
increased interleukin-1 beta secretion  (IAGP)
increased interleukin-2 secretion  (IAGP)
increased intestinal adenocarcinoma incidence  (IAGP)
increased lymphocyte cell number  (IAGP)
increased monocyte cell number  (IAGP)
increased neutrophil cell number  (IAGP)
increased physiological sensitivity to xenobiotic  (IAGP)
increased single-positive T cell number  (IAGP)
increased susceptibility to induced colitis  (IAGP)
increased susceptibility to parasitic infection  (IAGP)
increased susceptibility to xenobiotic induced morbidity/mortality  (IAGP)
increased T cell number  (IAGP)
increased T cell proliferation  (IAGP)
increased thymocyte number  (IAGP)
increased tumor necrosis factor secretion  (IAGP)
intestinal ulcer  (IAGP)
large intestinal inflammation  (IAGP)
lethality during fetal growth through weaning, complete penetrance  (IAGP)
lumbar vertebral fusion  (IAGP)
megacolon  (IAGP)
no abnormal phenotype detected  (IAGP)
peritoneal inflammation  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
pulmonary edema  (IAGP)
rectal prolapse  (IAGP)
respiratory distress  (IAGP)
rib fusion  (IAGP)
weakness  (IAGP)
weight loss  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Knockdown of Inhibitory Guanine Nucleotide Binding Protein Gia-2 by Antisense Oligodeoxynucleotides Attenuates the Development of Hypertension and Tachycardia in Spontaneously Hypertensive Rats. Ali El-Basyuni Y, etal., J Am Heart Assoc. 2016 Oct 26;5(11). pii: JAHA.116.004594. doi: 10.1161/JAHA.116.004594.
2. Molecular properties of muscarinic acetylcholine receptors. Haga T Proc Jpn Acad Ser B Phys Biol Sci. 2013;89(6):226-56.
3. Losartan-induced attenuation of blood pressure in L-NAME hypertensive rats is associated with reversal of the enhanced expression of Gi alpha proteins. Hashim S and Anand-Srivastava MB, J Hypertens. 2004 Jan;22(1):181-90.
4. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
5. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
6. Right ventricular outflow tract tachycardia due to a somatic cell mutation in G protein subunitalphai2. Lerman BB, etal., J Clin Invest. 1998 Jun 15;101(12):2862-8.
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. MGD IEA MGD IEA
9. Functionally selective dopamine D(2), D(3) receptor partial agonists. Moller D, etal., J Med Chem. 2014 Jun 12;57(11):4861-75. doi: 10.1021/jm5004039. Epub 2014 May 23.
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. AT2 receptors: beneficial counter-regulatory role in cardiovascular and renal function. Padia SH and Carey RM, Pflugers Arch. 2013 Jan;465(1):99-110. doi: 10.1007/s00424-012-1146-3. Epub 2012 Sep 5.
12. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
13. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
14. Mouse MP Annotation Import Pipeline RGD automated import pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. [Alteration of the expression of rat cardiac Galphaq/11 and Gialpha2 proteins during endothelin-1 pre-treatment]. Wang XT, etal., Sheng Li Xue Bao. 2000 Dec;52(6):459-62.
18. [Alterations of cardiac Gi protein alpha subunits during ischemia-reperfusion in rats]. Wang Y, etal., Sheng Li Xue Bao. 1998 Oct;50(5):514-8.
Additional References at PubMed
PMID:1302014   PMID:1354648   PMID:1421769   PMID:2123549   PMID:2508088   PMID:2572508   PMID:2820999   PMID:2902634   PMID:3092218   PMID:3117797   PMID:3138077   PMID:7656338  
PMID:7663509   PMID:7706278   PMID:7796808   PMID:7894156   PMID:8070621   PMID:8076637   PMID:8170357   PMID:8268981   PMID:8288240   PMID:8314596   PMID:8325648   PMID:8336951  
PMID:8486374   PMID:8588930   PMID:8613481   PMID:8622915   PMID:8641130   PMID:8858601   PMID:8889548   PMID:9013944   PMID:9023306   PMID:9192769   PMID:9223288   PMID:9576877  
PMID:9611134   PMID:10196137   PMID:10349636   PMID:10484490   PMID:10790434   PMID:10922068   PMID:10926822   PMID:11042159   PMID:11073886   PMID:11076861   PMID:11158953   PMID:11222144  
PMID:11248120   PMID:11299198   PMID:11487633   PMID:11489941   PMID:11685543   PMID:11771389   PMID:11906695   PMID:11950062   PMID:12171962   PMID:12297509   PMID:12466851   PMID:12477932  
PMID:12574334   PMID:12867032   PMID:14610273   PMID:14612574   PMID:14681479   PMID:14712229   PMID:14755341   PMID:15219458   PMID:15226823   PMID:15272018   PMID:15489334   PMID:15633125  
PMID:15684040   PMID:15684084   PMID:15723811   PMID:15728518   PMID:15780991   PMID:15782199   PMID:15788486   PMID:15879107   PMID:15885134   PMID:16141072   PMID:16141073   PMID:16456099  
PMID:16602821   PMID:16606834   PMID:16630814   PMID:16805845   PMID:16943428   PMID:16962188   PMID:17242370   PMID:17277016   PMID:17289675   PMID:17296938   PMID:17332478   PMID:17360531  
PMID:17415415   PMID:17418106   PMID:17484771   PMID:17490434   PMID:17575083   PMID:17579064   PMID:17688421   PMID:17699741   PMID:17928396   PMID:17938235   PMID:17967808   PMID:18064011  
PMID:18156202   PMID:18184563   PMID:18287559   PMID:18316484   PMID:18354186   PMID:18501427   PMID:18521956   PMID:18554416   PMID:18586242   PMID:18598698   PMID:18617557   PMID:18639553  
PMID:18799693   PMID:18832081   PMID:19225179   PMID:19387439   PMID:19401591   PMID:19487293   PMID:19519663   PMID:19638594   PMID:19906969   PMID:20495013   PMID:20508603   PMID:20534514  
PMID:20607800   PMID:20852125   PMID:20932279   PMID:21255617   PMID:21267068   PMID:21321602   PMID:21349876   PMID:21752992   PMID:21788441   PMID:21862448   PMID:21873635   PMID:21894149  
PMID:21931697   PMID:21966394   PMID:21966415   PMID:22039261   PMID:22308501   PMID:22544055   PMID:22550081   PMID:22581266   PMID:22581782   PMID:22590596   PMID:22706085   PMID:22794259  
PMID:22962436   PMID:22966200   PMID:23225882   PMID:23236180   PMID:23303817   PMID:23373526   PMID:23467353   PMID:23637329   PMID:23664818   PMID:23697798   PMID:23708969   PMID:23977324  
PMID:24135232   PMID:24298018   PMID:24457600   PMID:24478091   PMID:24816261   PMID:24858945   PMID:24899231   PMID:25044020   PMID:25205820   PMID:25225330   PMID:25431213   PMID:25617475  
PMID:25641781   PMID:25944935   PMID:26062014   PMID:26169941   PMID:26232433   PMID:26373672   PMID:26464333   PMID:26564126   PMID:26662512   PMID:26738537   PMID:26755700   PMID:26972746  
PMID:26976957   PMID:27034005   PMID:27499046   PMID:27787898   PMID:28235863   PMID:28323866   PMID:28378742   PMID:28646160   PMID:29342363   PMID:30068389   PMID:30233409   PMID:30550785  
PMID:30683698   PMID:30804203   PMID:30827920   PMID:30836096   PMID:30840837   PMID:30975754   PMID:31965032   PMID:32325033   PMID:32332099   PMID:32480042   PMID:32513692   PMID:32554809  
PMID:33278490   PMID:33641090   PMID:33679330   PMID:34001891   PMID:34135907   PMID:34294713   PMID:34322898   PMID:34413292   PMID:36260679   PMID:36293380   PMID:36383665   PMID:36808153  
PMID:37424020   PMID:37839992   PMID:38187761  


Genomics

Comparative Map Data
Gnai2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399107,491,324 - 107,512,542 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9107,491,324 - 107,512,566 (-)EnsemblGRCm39 Ensembl
GRCm389107,614,125 - 107,635,391 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9107,614,125 - 107,635,367 (-)EnsemblGRCm38mm10GRCm38
MGSCv379107,516,469 - 107,537,673 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369107,472,714 - 107,493,430 (-)NCBIMGSCv36mm8
Celera9107,222,922 - 107,240,939 (-)NCBICelera
Cytogenetic Map9F1NCBI
cM Map958.43NCBI
GNAI2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38350,227,068 - 50,263,358 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl350,226,292 - 50,259,362 (+)EnsemblGRCh38hg38GRCh38
GRCh37350,264,500 - 50,296,794 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36350,248,651 - 50,271,790 (+)NCBINCBI36Build 36hg18NCBI36
Build 34350,248,650 - 50,271,790NCBI
Celera350,246,476 - 50,269,614 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef350,329,335 - 50,352,473 (+)NCBIHuRef
CHM1_1350,225,922 - 50,249,058 (+)NCBICHM1_1
T2T-CHM13v2.0350,256,406 - 50,288,697 (+)NCBIT2T-CHM13v2.0
Gnai2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88117,167,045 - 117,187,652 (-)NCBIGRCr8
mRatBN7.28108,288,401 - 108,309,009 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8108,288,401 - 108,308,979 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8113,915,238 - 113,935,641 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08112,114,396 - 112,134,799 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08109,957,178 - 109,977,581 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08116,370,730 - 116,391,337 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8116,370,744 - 116,391,307 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08115,726,562 - 115,746,754 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48112,861,952 - 112,882,647 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18112,881,416 - 112,902,054 (-)NCBI
Celera8107,594,933 - 107,615,332 (-)NCBICelera
Cytogenetic Map8q32NCBI
Gnai2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555322,059,038 - 2,079,957 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555322,059,038 - 2,079,120 (+)NCBIChiLan1.0ChiLan1.0
GNAI2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2250,209,618 - 50,242,401 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1350,224,024 - 50,247,178 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0350,154,731 - 50,187,948 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1351,398,981 - 51,422,000 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl351,398,981 - 51,421,988 (+)Ensemblpanpan1.1panPan2
GNAI2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12039,075,085 - 39,094,697 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2039,075,085 - 39,094,697 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2038,996,147 - 39,015,757 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02039,431,154 - 39,450,979 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2039,430,574 - 39,451,075 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12038,798,956 - 38,818,559 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02039,202,455 - 39,222,063 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02039,482,556 - 39,502,160 (-)NCBIUU_Cfam_GSD_1.0
Gnai2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560265,019,103 - 65,040,746 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365291,779,571 - 1,801,255 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365291,779,582 - 1,801,251 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GNAI2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1332,705,321 - 32,733,794 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11332,705,326 - 32,733,804 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,891,199 - 35,912,182 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GNAI2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12211,623,394 - 11,646,464 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2211,623,408 - 11,647,191 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041155,339,947 - 155,363,875 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gnai2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247304,103,905 - 4,126,737 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247304,096,061 - 4,126,538 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gnai2
558 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:493
Count of miRNA genes:310
Interacting mature miRNAs:360
Transcripts:ENSMUST00000055704
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959897283109089068Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63239711120191934Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63239711120191934Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963239711120191934Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974250230108250378Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975682646114303447Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975682646114303447Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976417989110418183Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978522698112522808Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979279863113279941Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981680321115680445Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982792386116792481Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982792386116792481Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982792386116792481Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984406017118406120Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985779563108518385Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986107600120107729Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986121898120118690Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986625682120625682Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987677199121677199Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989162124123162124Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989289476123289595Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989440541123440541Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989859058118767089Mouse
12910770Splic1_mspleen iron content 1 (mouse)991291078124359700Mouse
12910772Lvic6_mliver iron content 6 (mouse)991291078124359700Mouse
12910773Splic3_mspleen iron content 3 (mouse)991291078124359700Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991518283124359700Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991518283124359700Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991518283124359700Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991518283124359700Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991518283124359700Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991518283124359700Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991560372124359700Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991560372124359700Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991560372124359700Mouse
1301484Bwq6_mbody weight (mouse)Not determined993591658124359700Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993591658124359700Mouse
14746992Manh67_mmandible shape 67 (mouse)993865836124359700Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994863354112701997Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996746658124359700Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9100889929124359700Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9101829255124359700Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9101829255124359700Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103118511124359700Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103118511124359700Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103118511124359700Mouse

Markers in Region
Gnai2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv379107,516,973 - 107,518,154UniSTSGRCm37
Celera9107,223,426 - 107,224,607UniSTS
Cytogenetic Map9F1UniSTS
cM Map959.0UniSTS
cM Map959.0UniSTS
MTH320  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389107,621,169 - 107,621,292UniSTSGRCm38
MGSCv379107,523,500 - 107,523,623UniSTSGRCm37
Celera9114,145,861 - 114,145,984UniSTS
Cytogenetic Map9F1UniSTS
cM Map961.0UniSTS
Whitehead Genetic961.2UniSTS
Whitehead/MRC_RH91107.98UniSTS
D9Mit278.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389107,621,219 - 107,621,328UniSTSGRCm38
MGSCv379107,523,550 - 107,523,659UniSTSGRCm37
Celera9114,145,825 - 114,145,934UniSTS
Cytogenetic Map9F1UniSTS
cM Map961.0UniSTS
cM Map9 UniSTS
Whitehead_YAC9 UniSTS
D9Dcr101  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389107,626,418 - 107,626,524UniSTSGRCm38
MGSCv379107,528,749 - 107,528,855UniSTSGRCm37
Celera9114,140,629 - 114,140,735UniSTS
Cytogenetic Map9F1UniSTS
cM Map9 UniSTS
RH125971  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389107,614,716 - 107,614,928UniSTSGRCm38
MGSCv379107,517,047 - 107,517,259UniSTSGRCm37
Celera9107,223,500 - 107,223,712UniSTS
Cytogenetic Map9F1UniSTS
cM Map959.0UniSTS
Whitehead/MRC_RH91107.55UniSTS
M13963  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9F1UniSTS
cM Map959.0UniSTS
Whitehead_YAC9 UniSTS
BI273769  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389107,614,429 - 107,614,619UniSTSGRCm38
MGSCv379107,516,760 - 107,516,950UniSTSGRCm37
Celera9107,223,213 - 107,223,403UniSTS
Cytogenetic Map9F1UniSTS
cM Map959.0UniSTS
Gnai2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389107,614,642 - 107,615,823UniSTSGRCm38
MGSCv379107,516,973 - 107,518,154UniSTSGRCm37
Celera9107,223,426 - 107,224,607UniSTS
Cytogenetic Map9F1UniSTS
cM Map959.0UniSTS
Gnai2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9F1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001410185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC162905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL672219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC006695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC037130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC065159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF951009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ134826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M13963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OU667060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S71213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S79607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000055704   ⟹   ENSMUSP00000057543
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9107,491,324 - 107,512,566 (-)Ensembl
GRCm38.p6 Ensembl9107,614,125 - 107,635,367 (-)Ensembl
RefSeq Acc Id: ENSMUST00000192615   ⟹   ENSMUSP00000142326
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9107,491,324 - 107,512,511 (-)Ensembl
GRCm38.p6 Ensembl9107,614,125 - 107,635,312 (-)Ensembl
RefSeq Acc Id: ENSMUST00000192837   ⟹   ENSMUSP00000141929
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9107,497,333 - 107,512,536 (-)Ensembl
GRCm38.p6 Ensembl9107,620,134 - 107,635,337 (-)Ensembl
RefSeq Acc Id: ENSMUST00000193372
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9107,493,424 - 107,494,671 (-)Ensembl
GRCm38.p6 Ensembl9107,616,225 - 107,617,472 (-)Ensembl
RefSeq Acc Id: ENSMUST00000193394   ⟹   ENSMUSP00000141472
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9107,493,700 - 107,503,805 (-)Ensembl
GRCm38.p6 Ensembl9107,616,501 - 107,626,606 (-)Ensembl
RefSeq Acc Id: ENSMUST00000193538
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9107,492,139 - 107,493,246 (-)Ensembl
GRCm38.p6 Ensembl9107,614,940 - 107,616,047 (-)Ensembl
RefSeq Acc Id: ENSMUST00000193835
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9107,496,779 - 107,512,533 (-)Ensembl
GRCm38.p6 Ensembl9107,619,580 - 107,635,334 (-)Ensembl
RefSeq Acc Id: ENSMUST00000193876   ⟹   ENSMUSP00000142060
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9107,512,299 - 107,512,542 (-)Ensembl
GRCm38.p6 Ensembl9107,635,100 - 107,635,343 (-)Ensembl
RefSeq Acc Id: ENSMUST00000195231
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9107,492,855 - 107,493,711 (-)Ensembl
GRCm38.p6 Ensembl9107,615,656 - 107,616,512 (-)Ensembl
RefSeq Acc Id: ENSMUST00000195762
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9107,497,211 - 107,498,147 (-)Ensembl
GRCm38.p6 Ensembl9107,620,012 - 107,620,948 (-)Ensembl
RefSeq Acc Id: NM_001410185   ⟹   NP_001397114
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399107,491,324 - 107,512,542 (-)NCBI
RefSeq Acc Id: NM_008138   ⟹   NP_032164
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399107,491,324 - 107,512,542 (-)NCBI
GRCm389107,614,125 - 107,635,343 (-)NCBI
MGSCv379107,516,469 - 107,537,673 (-)RGD
Celera9114,146,679 - 114,147,485 (+)NCBI
Celera9107,222,922 - 107,240,939 (-)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032164   ⟸   NM_008138
- UniProtKB: Q3TXK7 (UniProtKB/Swiss-Prot),   Q6P1C0 (UniProtKB/Swiss-Prot),   P08752 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000142060   ⟸   ENSMUST00000193876
RefSeq Acc Id: ENSMUSP00000141472   ⟸   ENSMUST00000193394
RefSeq Acc Id: ENSMUSP00000057543   ⟸   ENSMUST00000055704
RefSeq Acc Id: ENSMUSP00000142326   ⟸   ENSMUST00000192615
RefSeq Acc Id: ENSMUSP00000141929   ⟸   ENSMUST00000192837
RefSeq Acc Id: NP_001397114   ⟸   NM_001410185
- UniProtKB: Q3TXK7 (UniProtKB/Swiss-Prot),   P08752 (UniProtKB/Swiss-Prot),   Q6P1C0 (UniProtKB/Swiss-Prot)
Protein Domains
G-alpha

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P08752-F1-model_v2 AlphaFold P08752 1-355 view protein structure

Promoters
RGD ID:6848413
Promoter ID:MM_ACW:51953
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung,   MEF_B4,   Spleen
Transcripts:GNAI2.GSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369107,517,956 - 107,519,182 (-)MPROMDB
RGD ID:6844613
Promoter ID:MM_KWN:58734
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000055704,   UC009RMM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369107,537,574 - 107,538,074 (-)MPROMDB
RGD ID:8670818
Promoter ID:EPDNEW_M13439
Type:initiation region
Name:Gnai2_1
Description:Mus musculus guanine nucleotide binding protein , alpha inhibiting2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389107,635,343 - 107,635,403EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95772 AgrOrtholog
Ensembl Genes ENSMUSG00000032562 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000055704 ENTREZGENE
  ENSMUST00000055704.12 UniProtKB/Swiss-Prot
  ENSMUST00000192615 ENTREZGENE
  ENSMUST00000192615.6 UniProtKB/Swiss-Prot
  ENSMUST00000192837.2 UniProtKB/TrEMBL
  ENSMUST00000193394.2 UniProtKB/TrEMBL
  ENSMUST00000193876.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.400.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Gprotein_alpha_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gprotein_alpha_su UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GproteinA_insert UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14678 UniProtKB/Swiss-Prot
MGD MGI:95772 ENTREZGENE
NCBI Gene 14678 ENTREZGENE
PANTHER GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10218 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam G-alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gnai2 PhenoGen
PRINTS GPROTEINA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPROTEINAI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_ALPHA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART G_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47895 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A6YWA9_MOUSE UniProtKB/TrEMBL
  A0A0A6YXC2_MOUSE UniProtKB/TrEMBL
  A0A0A6YXN0_MOUSE UniProtKB/TrEMBL
  GNAI2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TXK7 ENTREZGENE
  Q6P1C0 ENTREZGENE
  Q8JZT4_MOUSE UniProtKB/TrEMBL
  Q922Y6_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q3TXK7 UniProtKB/Swiss-Prot
  Q6P1C0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-27 Gnai2  G protein subunit alpha i2  Gnai2  guanine nucleotide binding protein (G protein), alpha inhibiting 2  Symbol and/or name change 5135510 APPROVED