Epo (erythropoietin) - Rat Genome Database

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Gene: Epo (erythropoietin) Mus musculus
Symbol: Epo
Name: erythropoietin
RGD ID: 10531
Description: Exhibits protein kinase activator activity. Involved in several processes, including embryo implantation; erythrocyte differentiation; and hemoglobin biosynthetic process. Localizes to extracellular space. Is expressed in several structures, including egg cylinder; embryo mesenchyme; embryo mesoderm; nervous system; and placenta. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); diabetic angiopathy; familial erythrocytosis 5; ischemia (multiple); and neurodegenerative disease (multiple). Orthologous to human EPO (erythropoietin).
Type: protein-coding
RefSeq Status: REVIEWED
RGD Orthologs
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm395137,481,282 - 137,484,078 (-)NCBIGRCm39mm39
GRCm39 Ensembl5137,481,282 - 137,531,504 (-)Ensembl
GRCm385137,483,020 - 137,485,816 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,483,020 - 137,533,242 (-)EnsemblGRCm38mm10GRCm38
MGSCv375137,924,248 - 137,927,044 (-)NCBIGRCm37mm9NCBIm37
MGSCv365137,712,873 - 137,715,533 (-)NCBImm8
Celera5134,466,358 - 134,469,154 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (ISO)
Acute-Phase Reaction  (ISO)
AIDS Dementia Complex  (ISO)
Albuminuria  (ISO)
Alzheimer's disease  (ISO)
amyotrophic lateral sclerosis  (ISO)
Anastomotic Leak  (ISO)
anemia  (ISO)
beta thalassemia  (ISO)
Brain Hypoxia  (ISO)
Brain Injuries  (ISO)
breast cancer  (ISO)
calcinosis  (ISO)
Cardiogenic Shock  (ISO)
cardiomyopathy  (ISO)
central nervous system disease  (ISO)
cholangiocarcinoma  (ISO)
cognitive disorder  (ISO)
congenital diaphragmatic hernia  (ISO)
congestive heart failure  (ISO)
coronary artery disease  (ISO)
diabetic angiopathy  (ISO)
Diabetic Nephropathies  (ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (ISO)
Diamond-Blackfan Anemia-Like  (ISO)
end stage renal disease  (ISO)
Endotoxemia  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Autoimmune Neuritis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Sarcoma  (ISO)
familial erythrocytosis 5  (ISO)
Fatigue  (ISO)
Fetal Distress  (ISO)
gastric ulcer  (ISO)
glaucoma  (ISO)
heart disease  (ISO)
hemolytic anemia  (ISO)
hemolytic-uremic syndrome  (ISO)
Hemorrhagic Shock  (ISO)
high grade glioma  (ISO)
hypertension  (ISO)
hypoglycemia  (ISO)
Hypoxia-Ischemia, Brain  (ISO)
Inflammation  (ISO)
kidney disease  (ISO)
kidney failure  (ISO)
Kidney Reperfusion Injury  (ISO)
Knee Osteoarthritis  (ISO)
Limb Ischemia  (ISO)
Liver Reperfusion Injury  (ISO)
macular retinal edema  (ISO)
Mammary Neoplasms, Experimental  (ISO)
melanoma  (ISO)
Micronuclei, Chromosome-Defective  (ISO)
middle cerebral artery infarction  (ISO)
myelodysplastic syndrome  (ISO)
myocardial infarction  (ISO)
Necrosis  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
nephrotic syndrome  (ISO)
Nerve Degeneration  (ISO)
neurodegenerative disease  (ISO)
pancytopenia  (ISO)
Paraneoplastic Syndromes  (ISO)
Parkinson's disease  (ISO)
placental insufficiency  (ISO)
pleomorphic xanthoastrocytoma  (ISO)
Poisoning  (ISO)
polyneuropathy  (ISO)
porphyria  (ISO)
Pregnancy Complications  (ISO)
pulmonary embolism  (ISO)
pulmonary hypertension  (ISO)
retinal degeneration  (IMP)
retinal detachment  (ISO)
retinopathy of prematurity  (ISO)
severe combined immunodeficiency  (IMP)
Spinal Cord Compression  (ISO)
Spinal Cord Injuries  (ISO)
status epilepticus  (ISO)
Subarachnoid Hemorrhage  (ISO)
Subdural Hematoma, Acute  (ISO)
thrombocytopenia  (ISO)
thrombosis  (ISO)
Thyroid Neoplasms  (ISO)
transient cerebral ischemia  (ISO)
Tubulointerstitial Fibrosis  (ISO)
type 2 diabetes mellitus  (ISO)
uremia  (ISO)
vascular dementia  (ISO)
vascular disease  (ISO)
Venous Thrombosis  (ISO)
Ventricular Fibrillation  (ISO)
ventricular septal defect  (ISO)
Ventricular Tachycardia  (ISO)
visual epilepsy  (ISO)
Weight Loss  (ISO)
Wounds, Penetrating  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(R)-noradrenaline  (EXP)
(S)-nicotine  (ISO)
1-octadec-9-enoylglycero-3-phosphate  (ISO)
1H-indole  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methoxy-17beta-estradiol  (ISO)
2-naphthylamine  (ISO)
3',5'-cyclic AMP  (ISO)
3',5'-cyclic GMP  (EXP)
3,4-dihydroxybenzoic acid  (ISO)
5,6,7,8-tetrahydrobiopterin  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
5-chloro-7-iodoquinolin-8-ol  (ISO)
5-fluorouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
acetylcholine  (EXP)
Actein  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
amphotericin B  (ISO)
benzene  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (ISO)
BQ 123  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calycosin  (ISO)
calycosin-7-O-beta-D-glucoside  (ISO)
carbamazepine  (ISO)
carbon monoxide  (ISO)
carboplatin  (ISO)
ceftriaxone  (ISO)
cisplatin  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (EXP,ISO)
copper(II) sulfate  (ISO)
cortisol  (ISO)
curcumin  (ISO)
cycloheximide  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
cytochalasin B  (ISO)
D-glucose  (ISO)
dacarbazine  (ISO)
decabromodiphenyl ether  (ISO)
dehydroepiandrosterone  (ISO)
desferrioxamine B  (EXP,ISO)
dexamethasone  (ISO)
diclofenac  (ISO)
diethylstilbestrol  (ISO)
Dihydrotanshinone I  (ISO)
dioxygen  (EXP,ISO)
doxorubicin  (EXP,ISO)
EC (peptidyl-dipeptidase A) inhibitor  (ISO)
enalapril  (ISO)
etoposide  (ISO)
fenoterol  (ISO)
formaldehyde  (EXP)
formononetin  (ISO)
gentamycin  (ISO)
glucose  (ISO)
glutathione  (ISO)
haloperidol  (ISO)
hydrogen peroxide  (EXP,ISO)
hydroxyurea  (ISO)
indometacin  (ISO)
indoxyl sulfate  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
iron(III) citrate  (ISO)
kainic acid  (ISO)
ketoconazole  (ISO)
L-erythro-7,8-dihydrobiopterin  (EXP)
lipopolysaccharide  (EXP)
LY294002  (EXP,ISO)
malonaldehyde  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
menadione  (ISO)
mercury dichloride  (ISO)
methylmercury chloride  (ISO)
microcystin-LR  (EXP)
monosodium L-glutamate  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
neopterin  (EXP)
nicotine  (ISO)
nitric oxide  (ISO)
nitrites  (ISO)
nitrofen  (ISO)
nitroprusside  (ISO)
Nonidet P-40  (ISO)
ochratoxin A  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP)
paraquat  (EXP)
phenobarbital  (EXP)
phenylhydrazine  (ISO)
pirinixic acid  (EXP)
pyrogallol  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
reactive oxygen species  (EXP,ISO)
resveratrol  (ISO)
ribavirin  (ISO)
salubrinal  (ISO)
sapropterin  (EXP,ISO)
simvastatin  (ISO)
sodium stibogluconate  (ISO)
staurosporine  (ISO)
streptozocin  (ISO)
superoxide  (EXP)
testosterone  (ISO)
triptonide  (EXP)
urethane  (ISO)
zidovudine  (EXP,ISO)
zinc dichloride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acute-phase response  (ISO)
aging  (ISO)
angiogenesis  (TAS)
apoptotic process  (IDA)
cardiac muscle tissue morphogenesis  (TAS)
cellular hyperosmotic response  (ISO)
embryo implantation  (IDA)
erythrocyte differentiation  (IDA,ISO)
erythrocyte maturation  (IEA)
erythropoietin-mediated signaling pathway  (IBA,ISO)
heart morphogenesis  (TAS)
hemoglobin biosynthetic process  (IDA)
negative regulation of apoptotic process  (IDA)
negative regulation of calcium ion transport into cytosol  (ISO)
negative regulation of cation channel activity  (ISO)
negative regulation of erythrocyte apoptotic process  (ISO)
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress  (ISO)
negative regulation of myeloid cell apoptotic process  (IDA)
negative regulation of neuron death  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
peptidyl-serine phosphorylation  (IDA)
positive regulation of activated T cell proliferation  (ISO)
positive regulation of cell population proliferation  (IBA,ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of neuron differentiation  (ISO)
positive regulation of neuron projection development  (ISO)
positive regulation of protein kinase activity  (IDA)
positive regulation of Ras protein signal transduction  (IBA,ISO)
positive regulation of transcription, DNA-templated  (ISO)
positive regulation of tyrosine phosphorylation of STAT protein  (ISO)
regulation of transcription by RNA polymerase II  (IDA)
response to axon injury  (ISO)
response to dexamethasone  (ISO)
response to electrical stimulus  (ISO)
response to estrogen  (ISO)
response to hyperoxia  (ISO)
response to hypoxia  (IDA,ISO)
response to interleukin-1  (ISO)
response to lipopolysaccharide  (ISO)
response to nutrient  (ISO)
response to salt stress  (ISO)
response to testosterone  (ISO)
response to vitamin A  (ISO)
vasculogenesis involved in coronary vascular morphogenesis  (TAS)
ventricular cardiac muscle tissue morphogenesis  (TAS)
visceral serous pericardium development  (TAS)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal blood vessel morphology  (IAGP)
abnormal epicardium morphology  (IAGP)
abnormal erythropoiesis  (IAGP)
abnormal femur morphology  (IAGP)
abnormal heart development  (IAGP)
abnormal interventricular groove morphology  (IAGP)
abnormal interventricular septum morphology  (IAGP)
abnormal liver morphology  (IAGP)
abnormal liver physiology  (IAGP)
abnormal myocardial fiber physiology  (IAGP)
abnormal placenta morphology  (IAGP)
abnormal spleen morphology  (IAGP)
anemia  (IAGP)
decreased angiogenesis  (IAGP)
decreased bone marrow cell number  (IAGP)
decreased erythroblast number  (IAGP)
decreased erythrocyte cell number  (IAGP)
decreased fetal derived definitive erythrocyte cell number  (IAGP)
decreased hematocrit  (IAGP)
decreased hemoglobin content  (IAGP)
decreased oxygen consumption  (IAGP)
edema  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
enlarged heart  (IAGP)
enlarged myocardial fiber  (IAGP)
hemosiderosis  (IAGP)
hyperoxia  (IAGP)
hyperventilation  (IAGP)
hypoxia  (IAGP)
increased erythroid progenitor cell number  (IAGP)
increased heart right ventricle weight  (IAGP)
increased heart weight  (IAGP)
increased hepatocyte apoptosis  (IAGP)
increased left ventricle weight  (IAGP)
increased pulmonary ventilation  (IAGP)
increased spleen weight  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
pale liver  (IAGP)
pallor  (IAGP)
pericardial edema  (IAGP)
small liver  (IAGP)
thick ventricular wall  (IAGP)
ventricular hypoplasia  (IAGP)

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Additional References at PubMed
PMID:1284028   PMID:1302014   PMID:1307096   PMID:1358806   PMID:1535334   PMID:1617216   PMID:1683707   PMID:1685988   PMID:1707031   PMID:1889815   PMID:1961720   PMID:2766927  
PMID:3022133   PMID:3167219   PMID:3466025   PMID:3561395   PMID:3773894   PMID:7507352   PMID:7553874   PMID:7587381   PMID:7651724   PMID:7690439   PMID:7724539   PMID:7731971  
PMID:7734624   PMID:7893759   PMID:8007964   PMID:8032683   PMID:8080988   PMID:8111123   PMID:8148375   PMID:8241502   PMID:8264149   PMID:8353306   PMID:8380915   PMID:8396923  
PMID:8620534   PMID:8626614   PMID:8662221   PMID:8774484   PMID:8786423   PMID:8824813   PMID:8906421   PMID:9108383   PMID:9108390   PMID:9108392   PMID:9126492   PMID:9169414  
PMID:9286595   PMID:9365246   PMID:9434941   PMID:9558377   PMID:9704006   PMID:9811459   PMID:10051313   PMID:10067860   PMID:10198163   PMID:10341080   PMID:10352021   PMID:10383162  
PMID:10409505   PMID:10477715   PMID:10557295   PMID:10575226   PMID:10770291   PMID:10943842   PMID:11002334   PMID:11013070   PMID:11027359   PMID:11130978   PMID:11154234   PMID:11239002  
PMID:11297512   PMID:11396976   PMID:11520789   PMID:11919510   PMID:12068288   PMID:12121614   PMID:12147241   PMID:12239150   PMID:12381912   PMID:12393587   PMID:12393629   PMID:12440938  
PMID:12477932   PMID:12606578   PMID:12804176   PMID:12917333   PMID:14610273   PMID:14699131   PMID:14767829   PMID:14770308   PMID:15008895   PMID:15016652   PMID:15086902   PMID:15142852  
PMID:15170228   PMID:15215287   PMID:15375030   PMID:15456912   PMID:15525354   PMID:15531367   PMID:15591122   PMID:15635607   PMID:15642952   PMID:15705783   PMID:15752978   PMID:15766748  
PMID:15878311   PMID:15890996   PMID:16151855   PMID:16197514   PMID:16207820   PMID:16286456   PMID:16330260   PMID:16436614   PMID:16445835   PMID:16467207   PMID:16475009   PMID:16524748  
PMID:16527892   PMID:16534010   PMID:16581793   PMID:16731906   PMID:16783635   PMID:16787915   PMID:17141159   PMID:17185011   PMID:17300687   PMID:17353275   PMID:17372034   PMID:17404621  
PMID:17431131   PMID:17476283   PMID:17482474   PMID:17511959   PMID:17567717   PMID:17604282   PMID:17652365   PMID:17693141   PMID:17699753   PMID:17712557   PMID:17855480   PMID:17942981  
PMID:17969148   PMID:17981124   PMID:18188450   PMID:18202227   PMID:18207304   PMID:18219389   PMID:18278456   PMID:18341422   PMID:18382691   PMID:18397963   PMID:18454133   PMID:18617288  
PMID:18682290   PMID:18799693   PMID:19100675   PMID:19109375   PMID:19204324   PMID:19243017   PMID:19498162   PMID:19521513   PMID:19679834   PMID:19901910   PMID:19965681   PMID:20119684  
PMID:20299672   PMID:20385932   PMID:20395592   PMID:20400342   PMID:20414335   PMID:20458283   PMID:20463184   PMID:20523730   PMID:20554972   PMID:20651146   PMID:20861276   PMID:20959632  
PMID:21095239   PMID:21127173   PMID:21138976   PMID:21267068   PMID:21304510   PMID:21324364   PMID:21383158   PMID:21514445   PMID:21543202   PMID:21664343   PMID:21746884   PMID:21811636  
PMID:21816364   PMID:21833990   PMID:21873635   PMID:21894148   PMID:21911936   PMID:22022454   PMID:22138754   PMID:22207682   PMID:22342523   PMID:22351476   PMID:22387002   PMID:22464323  
PMID:22490927   PMID:22508938   PMID:22611156   PMID:22627278   PMID:22669473   PMID:22748015   PMID:22773876   PMID:22801437   PMID:22879008   PMID:23048191   PMID:23114598   PMID:23190530  
PMID:23333855   PMID:23383068   PMID:23393316   PMID:23398821   PMID:23426945   PMID:23523698   PMID:23554941   PMID:23565059   PMID:23656253   PMID:23676500   PMID:23727690   PMID:23833259  
PMID:24309470   PMID:24493804   PMID:24832733   PMID:24914467   PMID:24973448   PMID:25003898   PMID:25708005   PMID:25790231   PMID:25833080   PMID:25887124   PMID:25952549   PMID:26001375  
PMID:26054543   PMID:26146639   PMID:26166573   PMID:26680303   PMID:26731474   PMID:26755707   PMID:26872696   PMID:26885637   PMID:26927670   PMID:26936784   PMID:27067488   PMID:27082941  
PMID:27088801   PMID:27114509   PMID:27128622   PMID:27262376   PMID:27325674   PMID:27477940   PMID:27587397   PMID:27600268   PMID:27683416   PMID:27872856   PMID:27878722   PMID:27920250  
PMID:28288167   PMID:28298334   PMID:28383559   PMID:28410882   PMID:28438754   PMID:28527294   PMID:28735074   PMID:28744650   PMID:28867537   PMID:29029628   PMID:29073189   PMID:29395333  
PMID:29522896   PMID:29555646   PMID:29697839   PMID:30160360   PMID:30292638   PMID:30366982   PMID:30535439   PMID:30545903   PMID:30716313   PMID:31013255   PMID:31299495   PMID:31813828  
PMID:32029230   PMID:32152318   PMID:32556142   PMID:32721504   PMID:32907997   PMID:32950599   PMID:33255601  


Comparative Map Data
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm395137,481,282 - 137,484,078 (-)NCBIGRCm39mm39
GRCm39 Ensembl5137,481,282 - 137,531,504 (-)Ensembl
GRCm385137,483,020 - 137,485,816 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,483,020 - 137,533,242 (-)EnsemblGRCm38mm10GRCm38
MGSCv375137,924,248 - 137,927,044 (-)NCBIGRCm37mm9NCBIm37
MGSCv365137,712,873 - 137,715,533 (-)NCBImm8
Celera5134,466,358 - 134,469,154 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.5NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl7100,720,468 - 100,723,700 (+)EnsemblGRCh38hg38GRCh38
GRCh387100,720,468 - 100,723,700 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377100,318,091 - 100,321,323 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367100,156,359 - 100,159,259 (+)NCBINCBI36hg18NCBI36
Build 34799,963,073 - 99,965,972NCBI
Celera795,048,997 - 95,051,893 (+)NCBI
Cytogenetic Map7q22.1NCBI
HuRef794,949,230 - 94,952,126 (+)NCBIHuRef
CHM1_17100,248,723 - 100,251,623 (+)NCBICHM1_1
CRA_TCAGchr7v2799,678,028 - 99,680,928 (+)NCBI
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.21219,204,258 - 19,207,948 (+)NCBI
Rnor_6.0 Ensembl1222,274,828 - 22,278,266 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01222,274,828 - 22,278,268 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01224,291,481 - 24,294,921 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41219,551,768 - 19,555,208 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11219,541,291 - 19,544,730 (-)NCBI
Celera1221,009,353 - 21,012,793 (+)NCBICelera
Cytogenetic Map12q12NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0 EnsemblNW_004955573203,441 - 206,355 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955573203,875 - 206,078 (-)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.17106,148,062 - 106,150,974 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7106,148,062 - 106,150,974 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0792,747,671 - 92,750,886 (+)NCBIMhudiblu_PPA_v0panPan3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.168,994,211 - 8,995,954 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl68,994,211 - 8,996,144 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha610,698,441 - 10,700,425 (-)NCBI
ROS_Cfam_1.068,928,384 - 8,930,368 (-)NCBI
UMICH_Zoey_3.168,780,936 - 8,782,920 (-)NCBI
UNSW_CanFamBas_1.068,759,117 - 8,761,101 (-)NCBI
UU_Cfam_GSD_1.068,940,837 - 8,942,821 (-)NCBI
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_024409344133,290,130 - 133,295,627 (-)NCBI
SpeTri2.0NW_004936543742,722 - 745,332 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl38,620,508 - 8,622,936 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,620,508 - 8,622,936 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.238,014,859 - 8,017,287 (+)NCBISscrofa10.2Sscrofa10.2susScr3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.12812,487,222 - 12,491,986 (-)NCBI
ChlSab1.1 Ensembl2812,489,766 - 12,491,908 (-)Ensembl

Position Markers
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385137,483,212 - 137,484,128UniSTSGRCm38
MGSCv375137,924,440 - 137,925,356UniSTSGRCm37
Celera5134,466,550 - 134,467,466UniSTS
Cytogenetic Map5GUniSTS
cM Map578.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5GUniSTS
cM Map578.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5GUniSTS
cM Map578.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385137,484,377 - 137,484,496UniSTSGRCm38
MGSCv375137,925,605 - 137,925,724UniSTSGRCm37
Celera5134,467,715 - 134,467,834UniSTS
Cytogenetic Map5GUniSTS
cM Map578.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385137,484,194 - 137,484,356UniSTSGRCm38
MGSCv375137,925,422 - 137,925,584UniSTSGRCm37
Celera5134,467,532 - 134,467,694UniSTS
Cytogenetic Map5GUniSTS
cM Map578.0UniSTS

QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526236236138457140Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572700000140000000Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589271017146851125Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104435822138557193Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104567876138567876Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107829235141829348Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107829235141829348Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107829235141829348Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109090176143090317Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109090176143090317Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109090758139133150Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109362284143362395Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113172519138557193Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115128044149128176Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115128044149128176Mouse
1301857Bglq14_mbody growth late QTL 14 (mouse)Not determined5118920110151834684Mouse
10412191Bbaa24_mB.burgdorferi-associated arthritis 24 (mouse)Not determined5119806972141714711Mouse
4141081Nidd7k_mNidd7 on KK-A (mouse)Not determined119806972149423861Mouse
11528552Scram1_mspinal cord resistance to astrocytoma modifier 1 (mouse)5121457140151834684Mouse
1301986Bpq4_mblood pressure QTL 4 (mouse)Not determined5121556974151834684Mouse
1302079Lbw3_mlupus NZB x NZW 3 (mouse)Not determined5124714580151834684Mouse
1301715Elmaz2_melevated maze behavior 2 (mouse)Not determined5125101165141714711Mouse
1301363Pbwg13_mpostnatal body weight growth 13 (mouse)Not determined5125147702151834684Mouse
4141218Ath24_matherosclerosis 24 (mouse)Not determined129583274151834684Mouse
12880406Jcdq2_mjoint cartilage degeneration QTL 2 (mouse)5129851021151834684Mouse
11049557Lmr26_mleishmaniasis resistance 26 (mouse)5134002093151834684Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:972
Count of miRNA genes:283
Interacting mature miRNAs:375
Transcripts:ENSMUST00000031723, ENSMUST00000111038, ENSMUST00000111039
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.



Reference Sequences
RefSeq Acc Id: ENSMUST00000031723   ⟹   ENSMUSP00000031723
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl5137,483,020 - 137,485,816 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111038   ⟹   ENSMUSP00000106667
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl5137,483,020 - 137,533,242 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111039   ⟹   ENSMUSP00000106668
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl5137,483,026 - 137,485,816 (-)Ensembl
RefSeq Acc Id: NM_001312875   ⟹   NP_001299804
RefSeq Status: REVIEWED
Mouse AssemblyChrPosition (strand)Source
GRCm395137,481,282 - 137,484,078 (-)NCBI
GRCm385137,483,020 - 137,485,816 (-)NCBI
RefSeq Acc Id: NM_007942   ⟹   NP_031968
RefSeq Status: REVIEWED
Mouse AssemblyChrPosition (strand)Source
GRCm395137,481,282 - 137,484,078 (-)NCBI
GRCm385137,483,020 - 137,485,816 (-)ENTREZGENE
MGSCv375137,924,248 - 137,927,044 (-)RGD
Celera5134,466,358 - 134,469,154 (-)RGD
Reference Sequences
RefSeq Acc Id: NP_031968   ⟸   NM_007942
- Peptide Label: isoform 1 precursor
- UniProtKB: P07321 (UniProtKB/Swiss-Prot),   Q0VED9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001299804   ⟸   NM_001312875
- Peptide Label: isoform 2 precursor
- UniProtKB: B7ZMY9 (UniProtKB/TrEMBL),   Q0VED9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000106667   ⟸   ENSMUST00000111038
RefSeq Acc Id: ENSMUSP00000106668   ⟸   ENSMUST00000111039
RefSeq Acc Id: ENSMUSP00000031723   ⟸   ENSMUST00000031723

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95407 AgrOrtholog
Ensembl Genes ENSMUSG00000029711 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000031723 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000106667 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000031723 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000111038 UniProtKB/Swiss-Prot
InterPro 4_helix_cytokine-like_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EPO/TPO_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EPO_TPO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Erythroptn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:13856 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PANTHER PTHR10370 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EPO_TPO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Epo PhenoGen
PIRSF EPO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47266 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL