Xpnpep1 (X-prolyl aminopeptidase (aminopeptidase P) 1, soluble) - Rat Genome Database

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Gene: Xpnpep1 (X-prolyl aminopeptidase (aminopeptidase P) 1, soluble) Mus musculus
Analyze
Symbol: Xpnpep1
Name: X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
RGD ID: 733431
MGI Page MGI
Description: Predicted to enable manganese ion binding activity; metalloaminopeptidase activity; and protein homodimerization activity. Predicted to be involved in bradykinin catabolic process; negative regulation of programmed cell death; and proteolysis. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Orthologous to human XPNPEP1 (X-prolyl aminopeptidase 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: aminoacylproline aminopeptidase; cytosolic aminopeptidase P; D230045I08Rik; sAMP; soluble aminopeptidase P; X-Pro aminopeptidase 1; X-prolyl aminopeptidase 1, soluble; xaa-Pro aminopeptidase 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm19098  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391952,919,710 - 53,027,093 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1952,920,357 - 53,028,645 (-)EnsemblGRCm39 Ensembl
GRCm381952,931,279 - 53,038,662 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1952,931,926 - 53,040,214 (-)EnsemblGRCm38mm10GRCm38
MGSCv371953,065,673 - 53,113,032 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361953,044,495 - 53,091,854 (-)NCBIMGSCv36mm8
Celera1955,173,619 - 55,221,048 (-)NCBICelera
Cytogenetic Map19D2NCBI
cM Map1946.91NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO,ISS)
cytosol  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal aortic valve morphology  (IEA)
abnormal bile duct morphology  (IEA)
abnormal cranium morphology  (IEA)
abnormal eye muscle morphology  (IEA)
abnormal hypoglossal nerve topology  (IEA)
abnormal inferior vena cava morphology  (IEA)
abnormal inferior vena cava valve morphology  (IEA)
abnormal infrahyoid muscle connection  (IEA)
abnormal infrahyoid muscle morphology  (IEA)
abnormal intestine placement  (IEA)
abnormal mitral valve morphology  (IEA)
abnormal Mullerian duct morphology  (IEA)
abnormal superior vena cava morphology  (IEA)
abnormal survival  (IAGP)
abnormal thymus morphology  (IEA)
abnormal umbilical vein topology  (IEA)
abnormal urine color  (IAGP)
abnormal vertebral artery topology  (IEA)
abnormal vitelline vein topology  (IEA)
blood in lymph vessels  (IEA)
decreased birth body size  (IAGP)
decreased body length  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased brain size  (IAGP)
dilated liver sinusoidal space  (IEA)
embryo tumor  (IEA)
forebrain hypoplasia  (IAGP)
increased gamma-delta T cell number  (IEA)
increased hemangioma incidence  (IEA)
increased NK cell number  (IEA)
increased trigeminal neuroma incidence  (IEA)
increased urine protein level  (IAGP)
microcephaly  (IAGP)
muscular ventricular septal defect  (IEA)
postnatal growth retardation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, incomplete penetrance  (IEA)
subcutaneous edema  (IEA)
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. The kallikrein-kinin system: current and future pharmacological targets. Moreau ME, etal., J Pharmacol Sci. 2005 Sep;99(1):6-38.
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:12520002   PMID:14610273   PMID:15489334   PMID:15782199   PMID:16141072  
PMID:16141073   PMID:16682971   PMID:17967808   PMID:18799693   PMID:21677750   PMID:21873635   PMID:23131567   PMID:24457600   PMID:27899360   PMID:28378742   PMID:30973865   PMID:32325033  
PMID:33441619   PMID:36114006   PMID:38355793  


Genomics

Comparative Map Data
Xpnpep1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391952,919,710 - 53,027,093 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1952,920,357 - 53,028,645 (-)EnsemblGRCm39 Ensembl
GRCm381952,931,279 - 53,038,662 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1952,931,926 - 53,040,214 (-)EnsemblGRCm38mm10GRCm38
MGSCv371953,065,673 - 53,113,032 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361953,044,495 - 53,091,854 (-)NCBIMGSCv36mm8
Celera1955,173,619 - 55,221,048 (-)NCBICelera
Cytogenetic Map19D2NCBI
cM Map1946.91NCBI
XPNPEP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810109,864,766 - 109,923,511 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10109,864,766 - 109,923,553 (-)EnsemblGRCh38hg38GRCh38
GRCh3710111,624,524 - 111,683,269 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610111,614,514 - 111,673,192 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410111,614,513 - 111,673,192NCBI
Celera10105,356,208 - 105,414,975 (-)NCBICelera
Cytogenetic Map10q25.1NCBI
HuRef10105,255,598 - 105,314,375 (-)NCBIHuRef
CHM1_110111,906,232 - 111,965,041 (-)NCBICHM1_1
T2T-CHM13v2.010110,748,625 - 110,807,363 (-)NCBIT2T-CHM13v2.0
Xpnpep1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81262,006,761 - 262,057,479 (-)NCBIGRCr8
mRatBN7.21252,001,366 - 252,052,077 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1252,001,367 - 252,051,479 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1260,189,774 - 260,239,893 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01266,895,833 - 266,945,952 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01259,547,854 - 259,598,654 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01273,708,217 - 273,758,247 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1273,708,212 - 273,758,442 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01281,121,567 - 281,171,473 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41259,089,652 - 259,139,681 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11259,355,566 - 259,405,597 (-)NCBI
Celera1247,726,460 - 247,776,301 (-)NCBICelera
Cytogenetic Map1q55NCBI
Xpnpep1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554851,436,834 - 1,501,463 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554851,436,834 - 1,501,408 (+)NCBIChiLan1.0ChiLan1.0
XPNPEP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28121,743,866 - 121,802,631 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110121,749,204 - 121,807,967 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010106,457,390 - 106,516,111 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110109,908,285 - 109,967,100 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10109,908,285 - 109,967,094 (-)Ensemblpanpan1.1panPan2
XPNPEP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12821,267,588 - 21,322,044 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2821,246,467 - 21,321,953 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2821,410,929 - 21,465,285 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02821,782,248 - 21,836,736 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2821,760,215 - 21,836,755 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12821,343,307 - 21,397,639 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02821,342,664 - 21,397,127 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02821,482,813 - 21,537,258 (-)NCBIUU_Cfam_GSD_1.0
Xpnpep1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721324,708,158 - 24,759,708 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936486801,328 - 853,147 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936486801,563 - 853,107 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
XPNPEP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14120,315,910 - 120,367,780 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114120,316,578 - 120,367,995 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214131,108,925 - 131,204,866 (-)NCBISscrofa10.2Sscrofa10.2susScr3
XPNPEP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19102,792,424 - 102,840,479 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9102,782,895 - 102,784,895 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
ChlSab1.1 Ensembl9102,782,895 - 102,784,895 (-)NCBIChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604863,982,600 - 64,043,409 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Xpnpep1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473736,343,159 - 36,402,940 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Xpnpep1
4129 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2397
Count of miRNA genes:783
Interacting mature miRNAs:1013
Transcripts:ENSMUST00000069988, ENSMUST00000182097, ENSMUST00000182500, ENSMUST00000182534, ENSMUST00000182728, ENSMUST00000182844, ENSMUST00000182877, ENSMUST00000182887, ENSMUST00000182939, ENSMUST00000183108, ENSMUST00000183188, ENSMUST00000183274
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10043896Bw21_mbody weight QTL 21 (mouse)Not determined193959606661420004Mouse
4141659Pbwg20_mpostnatal body weight growth 20 (mouse)Not determined192137870555378928Mouse
13506250Renmq1_mrenal mercury accumulation QTL 1 (mouse)192738559461385705Mouse
4141019Tgq29_mtriglyceride QTL 29 (mouse)Not determined3459678661420004Mouse
10412251Mnp_mmodifier of Niemann Pick type C1 (mouse)Not determined192023431454234461Mouse
1301942Pas13_mpulmonary adenoma susceptibility 13 (mouse)Not determined193014123161420004Mouse
12790634Ebm1_mEpidermolysis Bullosa modifier 1 (mouse)192498843958988439Mouse
1302170Tanidd1_mtally ho associated non-insulin dependednt diabetes mellitus 1 (mouse)Not determined193675259761420004Mouse
1301466T2dm2_mtype 2 diabetes mellitus 2 (mouse)Not determined193837605061420004Mouse
1558876W3q14_mweight 3 weeks QTL 14 (mouse)Not determined192231332653911504Mouse
1300856Nobq2_mNew Zealand obese QTL 2 (mouse)Not determined193089788061420004Mouse
1302104Lfp1_mlong free running period 1 (mouse)Not determined193918406461420004Mouse
4141138Femwf11_mfemur work to failure 11 (mouse)Not determined2814034861420004Mouse
4141650Chldq9_mcholesterol and HDL QTL 9 (mouse)Not determined193788298261420004Mouse
1301410Cd8mts6_mCD8 memory T cell subset 6 (mouse)Not determined193014123161420004Mouse
11667075Led3_mlate embryonic death 3 (mouse)195108837859123872Mouse
1301639Stnn_mstriatal neuron number (mouse)Not determined193395195261420004Mouse
4142343Moen2_mmodifier of engrailed QTL 2 (mouse)Not determined192023431454234461Mouse
1301451Ath16_matherosclerosis 16 (mouse)Not determined192542691759427005Mouse
1300683Fembm7_mfemoral bone morphometry 7 (mouse)Not determined193014122461420004Mouse
1300585Pgia12_mproteoglycan induced arthritis 12 (mouse)Not determined194258685961420004Mouse
4141412Acsns1_mAngiostrongylus costaricensis nematode susceptibility 1 (mouse)Not determined4789788055026545Mouse
1301741Lith2_mlithogenic gene 2 (mouse)Not determined193299215861420004Mouse

Markers in Region
D19Mit7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381953,024,074 - 53,024,188UniSTSGRCm38
MGSCv371953,098,564 - 53,098,678UniSTSGRCm37
Celera1955,206,578 - 55,206,690UniSTS
Cytogenetic Map19D2UniSTS
cM Map1948.0UniSTS
Whitehead Genetic1938.3UniSTS
Whitehead/MRC_RH19552.48UniSTS
Whitehead_YAC19 UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001374834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_133216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011247158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011247159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017318075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030250761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC163221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF363970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK158597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB739220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC021534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC065174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ081210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ479925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY499711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000182097   ⟹   ENSMUSP00000138473
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1953,000,642 - 53,026,991 (-)Ensembl
GRCm38.p6 Ensembl1953,012,211 - 53,038,560 (-)Ensembl
Ensembl Acc Id: ENSMUST00000182500   ⟹   ENSMUSP00000138097
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1952,934,572 - 53,027,072 (-)Ensembl
GRCm38.p6 Ensembl1952,946,141 - 53,038,641 (-)Ensembl
Ensembl Acc Id: ENSMUST00000182534
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1952,998,498 - 53,008,562 (-)Ensembl
GRCm38.p6 Ensembl1953,010,067 - 53,020,131 (-)Ensembl
Ensembl Acc Id: ENSMUST00000182728
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1952,983,795 - 52,985,064 (-)Ensembl
GRCm38.p6 Ensembl1952,995,364 - 52,996,633 (-)Ensembl
Ensembl Acc Id: ENSMUST00000182844
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1953,000,613 - 53,002,035 (-)Ensembl
GRCm38.p6 Ensembl1953,012,182 - 53,013,604 (-)Ensembl
Ensembl Acc Id: ENSMUST00000182877
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1952,979,613 - 53,008,727 (-)Ensembl
GRCm38.p6 Ensembl1952,991,182 - 53,020,296 (-)Ensembl
Ensembl Acc Id: ENSMUST00000182887
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1953,005,857 - 53,020,576 (-)Ensembl
GRCm38.p6 Ensembl1953,017,426 - 53,032,145 (-)Ensembl
Ensembl Acc Id: ENSMUST00000182939
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1953,020,930 - 53,026,995 (-)Ensembl
GRCm38.p6 Ensembl1953,032,499 - 53,038,564 (-)Ensembl
Ensembl Acc Id: ENSMUST00000183108   ⟹   ENSMUSP00000138250
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1952,979,614 - 53,028,645 (-)Ensembl
GRCm38.p6 Ensembl1952,991,183 - 53,040,214 (-)Ensembl
Ensembl Acc Id: ENSMUST00000183188
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1952,996,322 - 53,003,771 (-)Ensembl
GRCm38.p6 Ensembl1953,007,891 - 53,015,340 (-)Ensembl
Ensembl Acc Id: ENSMUST00000183274   ⟹   ENSMUSP00000138233
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1952,931,848 - 53,026,984 (-)Ensembl
GRCm38.p6 Ensembl1952,943,417 - 53,038,553 (-)Ensembl
Ensembl Acc Id: ENSMUST00000235453
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1952,979,614 - 52,988,304 (-)Ensembl
GRCm38.p6 Ensembl1952,991,183 - 52,999,873 (-)Ensembl
Ensembl Acc Id: ENSMUST00000236008   ⟹   ENSMUSP00000158501
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1952,920,361 - 53,020,576 (-)Ensembl
GRCm38.p6 Ensembl1952,931,930 - 53,032,145 (-)Ensembl
Ensembl Acc Id: ENSMUST00000236058   ⟹   ENSMUSP00000157689
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1952,979,084 - 53,023,823 (-)Ensembl
GRCm38.p6 Ensembl1952,990,653 - 53,035,392 (-)Ensembl
Ensembl Acc Id: ENSMUST00000236456   ⟹   ENSMUSP00000157484
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1952,920,357 - 53,027,072 (-)Ensembl
GRCm38.p6 Ensembl1952,931,926 - 53,038,641 (-)Ensembl
Ensembl Acc Id: ENSMUST00000237294   ⟹   ENSMUSP00000158390
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1952,979,084 - 53,020,577 (-)Ensembl
GRCm38.p6 Ensembl1952,990,653 - 53,032,146 (-)Ensembl
Ensembl Acc Id: ENSMUST00000238001
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1952,979,611 - 52,993,335 (-)Ensembl
GRCm38.p6 Ensembl1952,991,180 - 53,004,904 (-)Ensembl
RefSeq Acc Id: NM_001374834   ⟹   NP_001361763
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391952,979,614 - 53,027,001 (-)NCBI
GRCm381952,991,183 - 53,038,570 (-)NCBI
Sequence:
RefSeq Acc Id: NM_133216   ⟹   NP_573479
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391952,979,614 - 53,027,001 (-)NCBI
GRCm381952,991,180 - 53,038,654 (-)NCBI
MGSCv371953,065,673 - 53,113,032 (-)RGD
Celera1955,173,616 - 55,221,160 (-)NCBI
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011247158   ⟹   XP_011245460
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391952,919,710 - 53,027,093 (-)NCBI
GRCm381952,931,279 - 53,038,662 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011247159   ⟹   XP_011245461
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391952,979,612 - 53,021,075 (-)NCBI
GRCm381952,991,181 - 53,032,644 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017318075   ⟹   XP_017173564
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391952,979,612 - 53,003,783 (-)NCBI
GRCm381952,991,181 - 53,015,341 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030250761   ⟹   XP_030106621
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391952,919,710 - 53,027,078 (-)NCBI
GRCm381952,931,924 - 53,038,652 (-)NCBI
Sequence:
RefSeq Acc Id: NP_573479   ⟸   NM_133216
- Peptide Label: isoform 1
- UniProtKB: S4R1I3 (UniProtKB/TrEMBL),   Q3UE92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011245460   ⟸   XM_011247158
- Peptide Label: isoform X1
- UniProtKB: S4R1I3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011245461   ⟸   XM_011247159
- Peptide Label: isoform X2
- UniProtKB: Q6P1B1 (UniProtKB/Swiss-Prot),   Q91Y37 (UniProtKB/Swiss-Prot),   Q3TL27 (UniProtKB/TrEMBL),   Q3UKF5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017173564   ⟸   XM_017318075
- Peptide Label: isoform X4
- UniProtKB: Q3TL27 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030106621   ⟸   XM_030250761
- Peptide Label: isoform X3
- UniProtKB: A0A494BBG8 (UniProtKB/TrEMBL),   Q3TL27 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001361763   ⟸   NM_001374834
- Peptide Label: isoform 2
- UniProtKB: Q6P1B1 (UniProtKB/Swiss-Prot),   Q91Y37 (UniProtKB/Swiss-Prot),   Q3UKF5 (UniProtKB/TrEMBL),   Q3TL27 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000158390   ⟸   ENSMUST00000237294
Ensembl Acc Id: ENSMUSP00000138250   ⟸   ENSMUST00000183108
Ensembl Acc Id: ENSMUSP00000138233   ⟸   ENSMUST00000183274
Ensembl Acc Id: ENSMUSP00000157484   ⟸   ENSMUST00000236456
Ensembl Acc Id: ENSMUSP00000158501   ⟸   ENSMUST00000236008
Ensembl Acc Id: ENSMUSP00000157689   ⟸   ENSMUST00000236058
Ensembl Acc Id: ENSMUSP00000138097   ⟸   ENSMUST00000182500
Ensembl Acc Id: ENSMUSP00000138473   ⟸   ENSMUST00000182097
Protein Domains
Creatinase N-terminal   Peptidase M24   Peptidase M24 C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P1B1-F1-model_v2 AlphaFold Q6P1B1 1-623 view protein structure

Promoters
RGD ID:13679762
Promoter ID:EPDNEW_M24030
Type:initiation region
Name:Xpnpep1_2
Description:Mus musculus X-prolyl aminopeptidase 1, soluble , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M24031  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381953,032,118 - 53,032,178EPDNEW
RGD ID:13679764
Promoter ID:EPDNEW_M24031
Type:initiation region
Name:Xpnpep1_1
Description:Mus musculus X-prolyl aminopeptidase 1, soluble , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M24030  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381953,038,570 - 53,038,630EPDNEW
RGD ID:6847616
Promoter ID:MM_ACW:27116
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:XPNPEP1.JSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361953,080,541 - 53,081,041 (-)MPROMDB
RGD ID:6830513
Promoter ID:MM_KWN:27326
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000111747,   UC008HWF.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361953,112,946 - 53,113,446 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2180003 AgrOrtholog
Ensembl Genes ENSMUSG00000025027 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000182097.2 UniProtKB/TrEMBL
  ENSMUST00000182500.8 UniProtKB/TrEMBL
  ENSMUST00000182877 ENTREZGENE
  ENSMUST00000183108 ENTREZGENE
  ENSMUST00000183108.8 UniProtKB/TrEMBL
  ENSMUST00000183274.8 UniProtKB/TrEMBL
  ENSMUST00000236008 ENTREZGENE
  ENSMUST00000236008.2 UniProtKB/TrEMBL
  ENSMUST00000236058.2 UniProtKB/Swiss-Prot
  ENSMUST00000236456.2 UniProtKB/TrEMBL
  ENSMUST00000237294 ENTREZGENE
  ENSMUST00000237294.2 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.350.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.230.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Creatin/AminoP/Spt16_NTD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Creatinase/aminopeptidase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Creatinase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M24 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M24B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M24_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M24B_aminopep-P_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  X-Pro_aminopeptidase_P UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:170750 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2180003 ENTREZGENE
NCBI Gene 170750 ENTREZGENE
PANTHER XAA-PRO AMINOPEPTIDASE 1 UniProtKB/Swiss-Prot
  XAA-PRO AMINOPEPTIDASE 1 UniProtKB/Swiss-Prot
  XAA-PRO AMINOPEPTIDASE 1 UniProtKB/TrEMBL
  XAA-PRO AMINOPEPTIDASE 1 UniProtKB/TrEMBL
Pfam Creatinase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Creatinase_N_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M24 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M24_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Xpnpep1 PhenoGen
PROSITE PROLINE_PEPTIDASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53092 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55920 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A494BBG8 ENTREZGENE, UniProtKB/TrEMBL
  Q3TL27 ENTREZGENE, UniProtKB/TrEMBL
  Q3UE92 ENTREZGENE, UniProtKB/TrEMBL
  Q3UKF5 ENTREZGENE, UniProtKB/TrEMBL
  Q6P1B1 ENTREZGENE
  Q8BKH1_MOUSE UniProtKB/TrEMBL
  Q8BV43_MOUSE UniProtKB/TrEMBL
  Q8VDK8_MOUSE UniProtKB/TrEMBL
  Q91Y37 ENTREZGENE
  S4R167_MOUSE UniProtKB/TrEMBL
  S4R1I3 ENTREZGENE, UniProtKB/TrEMBL
  S4R228_MOUSE UniProtKB/TrEMBL
  XPP1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q91Y37 UniProtKB/Swiss-Prot