Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Bche (butyrylcholinesterase) Mus musculus
Symbol: Bche
Name: butyrylcholinesterase
Description: Exhibits acetylcholinesterase activity. Predicted to be involved in several processes, including choline metabolic process; neuroblast differentiation; and response to folic acid. Localizes to endoplasmic reticulum and nuclear envelope lumen. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease (multiple); diabetes mellitus (multiple); epilepsy; and inherited metabolic disorder. Is expressed in several structures, including adrenal gland; alimentary system; ear; liver; and nervous system. Orthologous to human BCHE (butyrylcholinesterase); PARTICIPATES IN heroin pharmacodynamics pathway; heroin pharmacokinetics pathway; irinotecan pharmacodynamics pathway; INTERACTS WITH (+)-alpha-tocopherol; (2-chloroethyl)phosphonic acid; (R)-lipoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: acylcholine acylhydrolase; butyrylcholine esterase; C730038G20Rik; choline esterase II; cholinesterase; MGC107651; pseudocholinesterase
Homo sapiens (human) : BCHE (butyrylcholinesterase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bche (butyrylcholinesterase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bche (butyrylcholinesterase)
Pan paniscus (bonobo/pygmy chimpanzee) : BCHE (butyrylcholinesterase)
Canis lupus familiaris (dog) : BCHE (butyrylcholinesterase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bche (butyrylcholinesterase)
Sus scrofa (pig) : BCHE (butyrylcholinesterase)
Chlorocebus sabaeus (African green monkey) : BCHE (butyrylcholinesterase)
Heterocephalus glaber (naked mole-rat) : Bche (butyrylcholinesterase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl373,635,808 - 73,708,415 (-)EnsemblGRCm38mm10GRCm38
GRCm38373,635,805 - 73,708,436 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37373,439,731 - 73,512,337 (-)NCBIGRCm37mm9NCBIm37
MGSCv36373,721,734 - 73,794,168 (-)NCBImm8
Celera373,748,016 - 73,817,761 (-)NCBICelera
Cytogenetic Map3E3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Bche
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732175
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.