Unc13a (unc-13 homolog A) - Rat Genome Database
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Gene: Unc13a (unc-13 homolog A) Mus musculus
Analyze
Symbol: Unc13a
Name: unc-13 homolog A
RGD ID: 1614780
MGI Page MGI
Description: Exhibits diacylglycerol binding activity. Involved in several processes, including amyloid-beta metabolic process; chemical synaptic transmission; and modulation of chemical synaptic transmission. Localizes to several cellular components, including calyx of Held; glutamatergic synapse; and neuromuscular junction. Is expressed in nervous system and neural retina. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human UNC13A (unc-13 homolog A); PARTICIPATES IN insulin secretion pathway; INTERACTS WITH 1,2-dimethylhydrazine; benzo[a]pyrene; choline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410078G03Rik; C630025L14; Munc13-; Munc13-1; protein unc-13 homolog A; unc-13 homolog A (C. elegans)
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39872,079,356 - 72,124,418 (-)NCBIGRCm39mm39
GRCm38871,624,125 - 71,671,774 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl871,624,417 - 71,671,757 (-)EnsemblGRCm38mm10GRCm38
MGSCv37874,150,611 - 74,195,656 (-)NCBIGRCm37mm9NCBIm37
MGSCv36874,558,412 - 74,600,636 (-)NCBImm8
Celera874,140,993 - 74,186,237 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10349636   PMID:10440375   PMID:10488064   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11792326   PMID:11832228   PMID:12070347   PMID:12466851   PMID:12477932   PMID:14610273  
PMID:15123597   PMID:15893389   PMID:15988013   PMID:16141072   PMID:16141073   PMID:16644700   PMID:16697276   PMID:16782817   PMID:17124501   PMID:17167095   PMID:17267576   PMID:17561838  
PMID:17639022   PMID:18701688   PMID:18703708   PMID:18799693   PMID:18854036   PMID:19558619   PMID:19812333   PMID:19996097   PMID:21040848   PMID:21267068   PMID:21805469   PMID:21873635  
PMID:22066784   PMID:22814762   PMID:22966208   PMID:23070049   PMID:23229896   PMID:23658173   PMID:23770256   PMID:23791195   PMID:23801330   PMID:24814481   PMID:25374362   PMID:25609709  
PMID:26575293   PMID:27154627   PMID:27466336   PMID:28049845   PMID:28192369   PMID:28264913   PMID:28426965   PMID:28489077   PMID:28635948   PMID:28671696   PMID:28772123   PMID:29518331  
PMID:30816091   PMID:32187536  


Genomics

Comparative Map Data
Unc13a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39872,079,356 - 72,124,418 (-)NCBIGRCm39mm39
GRCm38871,624,125 - 71,671,774 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl871,624,417 - 71,671,757 (-)EnsemblGRCm38mm10GRCm38
MGSCv37874,150,611 - 74,195,656 (-)NCBIGRCm37mm9NCBIm37
MGSCv36874,558,412 - 74,600,636 (-)NCBImm8
Celera874,140,993 - 74,186,237 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
UNC13A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1917,601,328 - 17,688,365 (-)EnsemblGRCh38hg38GRCh38
GRCh381917,601,328 - 17,688,354 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371917,712,137 - 17,799,123 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361917,573,137 - 17,660,401 (-)NCBINCBI36hg18NCBI36
Celera1917,613,819 - 17,700,754 (-)NCBI
Cytogenetic Map19p13.11NCBI
HuRef1917,276,161 - 17,362,803 (-)NCBIHuRef
CHM1_11917,711,616 - 17,798,549 (-)NCBICHM1_1
Unc13a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01620,056,398 - 20,103,951 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,056,765 - 20,097,287 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01619,917,585 - 19,964,219 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41618,827,405 - 18,872,461 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11618,827,402 - 18,872,453 (-)NCBI
Celera1618,539,912 - 18,584,310 (-)NCBICelera
Cytogenetic Map16p14NCBI
Unc13a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955524725,353 - 769,745 (+)NCBIChiLan1.0ChiLan1.0
UNC13A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11918,063,260 - 18,150,713 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1918,068,006 - 18,150,642 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01917,088,654 - 17,175,559 (-)NCBIMhudiblu_PPA_v0panPan3
UNC13A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2045,188,750 - 45,238,115 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12045,179,275 - 45,237,544 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Unc13a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365963,311,358 - 3,370,833 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNC13A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1260,057,926 - 60,130,015 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2259,626,729 - 59,665,341 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UNC13A
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1616,082,703 - 16,167,165 (-)NCBI
ChlSab1.1 Ensembl616,084,168 - 16,154,812 (-)Ensembl
Unc13a
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624908418,248 - 464,203 (+)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86826982782600347Mouse
1301872Cd4ts3_mCD4 T cell subset 3 (mouse)Not determined871396181105396393Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84429488078295025Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined870305375104305495Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84773713481737254Mouse
4141395Char2a_mP. chabaudi malaria resistance QTL 2a (mouse)Not determined7113678390202598Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84763703081637146Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined870305375104305495Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71287817123895615Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871287817123895615Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1558780Idd22_minsulin dependent diabetes susceptibility 22 (mouse)Not determined871102903105103009Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84879293982793021Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84763703081637146Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2842
Count of miRNA genes:893
Interacting mature miRNAs:1213
Transcripts:ENSMUST00000030170, ENSMUST00000175780, ENSMUST00000175909, ENSMUST00000176127, ENSMUST00000176426, ENSMUST00000176777, ENSMUST00000177032, ENSMUST00000177517
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001029873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006509692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006509693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017312874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017312875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017312877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017312878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017312879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017312880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017312881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017312882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017312883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030243646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036154142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001778450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_379044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC162033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK039579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY753536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01112960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01112964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01135883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01135888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01135892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01135896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01214574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB250050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ106055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ250255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000030170   ⟹   ENSMUSP00000030170
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl871,624,417 - 71,671,757 (-)Ensembl
RefSeq Acc Id: ENSMUST00000175780
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl871,660,346 - 71,668,082 (-)Ensembl
RefSeq Acc Id: ENSMUST00000175909   ⟹   ENSMUSP00000135528
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl871,634,623 - 71,641,397 (-)Ensembl
RefSeq Acc Id: ENSMUST00000176127   ⟹   ENSMUSP00000135578
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl871,641,460 - 71,645,953 (-)Ensembl
RefSeq Acc Id: ENSMUST00000176426   ⟹   ENSMUSP00000135032
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl871,653,607 - 71,658,495 (-)Ensembl
RefSeq Acc Id: ENSMUST00000176777
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl871,660,341 - 71,671,741 (-)Ensembl
RefSeq Acc Id: ENSMUST00000177032
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl871,634,889 - 71,642,568 (-)Ensembl
RefSeq Acc Id: ENSMUST00000177517   ⟹   ENSMUSP00000135189
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl871,629,054 - 71,671,736 (-)Ensembl
RefSeq Acc Id: NM_001029873   ⟹   NP_001025044
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39872,079,356 - 72,124,401 (-)NCBI
GRCm38871,626,712 - 71,671,757 (-)NCBI
MGSCv37874,150,611 - 74,195,656 (-)RGD
Celera874,140,993 - 74,186,237 (-)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006509692   ⟹   XP_006509755
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39872,080,009 - 72,124,416 (-)NCBI
GRCm38871,624,125 - 71,671,773 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006509693   ⟹   XP_006509756
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39872,080,009 - 72,124,416 (-)NCBI
GRCm38871,624,125 - 71,671,773 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017312874   ⟹   XP_017168363
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39872,080,009 - 72,124,416 (-)NCBI
GRCm38871,624,125 - 71,671,773 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017312875   ⟹   XP_017168364
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39872,080,009 - 72,124,417 (-)NCBI
GRCm38871,624,125 - 71,671,773 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017312877   ⟹   XP_017168366
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39872,080,009 - 72,124,416 (-)NCBI
GRCm38871,624,125 - 71,671,773 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017312878   ⟹   XP_017168367
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39872,080,009 - 72,124,416 (-)NCBI
GRCm38871,624,125 - 71,671,773 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017312879   ⟹   XP_017168368
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39872,080,009 - 72,124,416 (-)NCBI
GRCm38871,624,125 - 71,671,773 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017312880   ⟹   XP_017168369
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39872,080,009 - 72,124,416 (-)NCBI
GRCm38871,624,125 - 71,671,772 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017312881   ⟹   XP_017168370
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39872,080,009 - 72,124,416 (-)NCBI
GRCm38871,624,125 - 71,671,773 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017312882   ⟹   XP_017168371
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39872,080,009 - 72,124,416 (-)NCBI
GRCm38871,624,125 - 71,671,773 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017312883   ⟹   XP_017168372
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39872,080,009 - 72,124,416 (-)NCBI
GRCm38871,624,125 - 71,671,772 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030243646   ⟹   XP_030099506
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39872,080,009 - 72,124,416 (-)NCBI
GRCm38871,624,125 - 71,671,773 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036154142   ⟹   XP_036010035
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39872,080,009 - 72,113,694 (-)NCBI
RefSeq Acc Id: XR_001778450
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39872,087,533 - 72,124,417 (-)NCBI
GRCm38871,634,889 - 71,671,773 (-)NCBI
Sequence:
RefSeq Acc Id: XR_379044
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39872,087,256 - 72,124,418 (-)NCBI
GRCm38871,645,744 - 71,671,774 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001025044   ⟸   NM_001029873
- UniProtKB: Q4KUS2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006509756   ⟸   XM_006509693
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006509755   ⟸   XM_006509692
- Peptide Label: isoform X3
- UniProtKB: H3BJZ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017168364   ⟸   XM_017312875
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017168368   ⟸   XM_017312879
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_017168363   ⟸   XM_017312874
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017168372   ⟸   XM_017312883
- Peptide Label: isoform X13
- Sequence:
RefSeq Acc Id: XP_017168371   ⟸   XM_017312882
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_017168370   ⟸   XM_017312881
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_017168369   ⟸   XM_017312880
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_017168367   ⟸   XM_017312878
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017168366   ⟸   XM_017312877
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_030099506   ⟸   XM_030243646
- Peptide Label: isoform X5
RefSeq Acc Id: ENSMUSP00000135189   ⟸   ENSMUST00000177517
RefSeq Acc Id: ENSMUSP00000135032   ⟸   ENSMUST00000176426
RefSeq Acc Id: ENSMUSP00000030170   ⟸   ENSMUST00000030170
RefSeq Acc Id: ENSMUSP00000135578   ⟸   ENSMUST00000176127
RefSeq Acc Id: ENSMUSP00000135528   ⟸   ENSMUST00000175909
RefSeq Acc Id: XP_036010035   ⟸   XM_036154142
- Peptide Label: isoform X11
Protein Domains
C2   MHD1   MHD2   Phorbol-ester/DAG-type

Promoters
RGD ID:8667425
Promoter ID:EPDNEW_M11743
Type:initiation region
Name:Unc13a_1
Description:Mus musculus unc-13 homolog A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38871,671,741 - 71,671,801EPDNEW
RGD ID:6843094
Promoter ID:MM_KWN:54809
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000098642,   UC009MEG.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36874,148,981 - 74,154,047 (-)MPROMDB
RGD ID:6843860
Promoter ID:MM_KWN:54810
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day3,   BoneMarrow_2Hour,   Brain,   ES_Cell,   Kidney,   Liver,   MEF_B6
Transcripts:ENSMUST00000030170,   ENSMUST00000066644,   NM_001029873,   UC009MEI.1,   UC009MEJ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36874,195,464 - 74,195,964 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3051532 AgrOrtholog
Ensembl Genes ENSMUSG00000034799 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000030170 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000135032 UniProtKB/TrEMBL
  ENSMUSP00000135189 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000135528 UniProtKB/TrEMBL
  ENSMUSP00000135578 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000030170 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000175909 UniProtKB/TrEMBL
  ENSMUST00000176127 UniProtKB/TrEMBL
  ENSMUST00000176426 UniProtKB/TrEMBL
  ENSMUST00000177517 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CAPS_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAG/PE-bd UniProtKB/TrEMBL
  Munc13_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Munc13_dom-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Munc13_subgr_dom-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Unc-13 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Unc-13_C2B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Unc13A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:382018 UniProtKB/Swiss-Prot
MGD MGI:3051532 ENTREZGENE
NCBI Gene 382018 ENTREZGENE
PANTHER PTHR10480 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10480:SF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DUF1041 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Membr_traf_MHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00168 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Unc13a PhenoGen
PRINTS C2DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAGPEDOMAIN UniProtKB/TrEMBL
PROSITE MHD1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHD2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50004 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DUF1041 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00109 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00239 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.334606 ENTREZGENE
UniProt H3BJL3_MOUSE UniProtKB/TrEMBL
  H3BJZ7 ENTREZGENE, UniProtKB/TrEMBL
  H3BKU4_MOUSE UniProtKB/TrEMBL
  H3BKY4_MOUSE UniProtKB/TrEMBL
  Q3URB8_MOUSE UniProtKB/TrEMBL
  Q4KUS2 ENTREZGENE
  Q6PE14_MOUSE UniProtKB/TrEMBL
  Q8C426_MOUSE UniProtKB/TrEMBL
  UN13A_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary E9QKH9 UniProtKB/Swiss-Prot
  Q3UHG2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-06-05 Unc13a  unc-13 homolog A    unc-13 homolog A (C. elegans)  Symbol and/or name change 5135510 APPROVED