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Gene: Adora1 (adenosine A1 receptor) Mus musculus
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Symbol: Adora1
Name: adenosine A1 receptor
Description: Predicted to have several functions, including G-protein beta/gamma-subunit complex binding activity; heterotrimeric G-protein binding activity; and neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration. Involved in several processes, including negative regulation of long-term synaptic depression; negative regulation of mucus secretion; and regulation of glomerular filtration. Localizes to the dendritic spine. Human ortholog(s) of this gene implicated in asthma. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and liver and biliary system. Orthologous to human ADORA1 (adenosine A1 receptor); INTERACTS WITH 1,2-dichloroethane; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A1-AR; A1AR; A1R; AA1R; adenosine receptor A1; AI848715; ARA1; BB176431; Ri
Orthologs:
Homo sapiens (human) : ADORA1 (adenosine A1 receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Adora1 (adenosine A1 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adora1 (adenosine A1 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : ADORA1 (adenosine A1 receptor)
Canis lupus familiaris (dog) : ADORA1 (adenosine A1 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adora1 (adenosine A1 receptor)
Sus scrofa (pig) : ADORA1 (adenosine A1 receptor)
Chlorocebus sabaeus (African green monkey) : ADORA1 (adenosine A1 receptor)
Heterocephalus glaber (naked mole-rat) : Adora1 (adenosine A1 receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1134,199,223 - 134,235,431 (-)Ensembl
GRCm381134,199,215 - 134,235,457 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371136,095,799 - 136,132,008 (-)NCBIGRCm37mm9NCBIm37
MGSCv361136,015,633 - 136,051,842 (-)NCBImm8
Celera1136,811,730 - 136,847,958 (-)NCBICelera
Cytogenetic Map1 E4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Adora1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730818
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.