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Gene: Adora1 (adenosine A1 receptor) Mus musculus
Symbol: Adora1
Name: adenosine A1 receptor
Description: Predicted to have several functions, including G-protein beta/gamma-subunit complex binding activity; heterotrimeric G-protein binding activity; and neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration. Involved in several processes, including negative regulation of long-term synaptic depression; negative regulation of mucus secretion; and regulation of glomerular filtration. Localizes to the dendritic spine. Human ortholog(s) of this gene implicated in asthma. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and liver and biliary system. Orthologous to human ADORA1 (adenosine A1 receptor); INTERACTS WITH 1,2-dichloroethane; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A1-AR; A1AR; A1R; AA1R; adenosine receptor A1; AI848715; ARA1; BB176431; Ri
Homo sapiens (human) : ADORA1 (adenosine A1 receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Adora1 (adenosine A1 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adora1 (adenosine A1 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : ADORA1 (adenosine A1 receptor)
Canis lupus familiaris (dog) : ADORA1 (adenosine A1 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adora1 (adenosine A1 receptor)
Sus scrofa (pig) : ADORA1 (adenosine A1 receptor)
Chlorocebus sabaeus (African green monkey) : ADORA1 (adenosine A1 receptor)
Heterocephalus glaber (naked mole-rat) : Adora1 (adenosine A1 receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1134,199,223 - 134,235,431 (-)Ensembl
GRCm381134,199,215 - 134,235,457 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371136,095,799 - 136,132,008 (-)NCBIGRCm37mm9NCBIm37
MGSCv361136,015,633 - 136,051,842 (-)NCBImm8
Celera1136,811,730 - 136,847,958 (-)NCBICelera
Cytogenetic Map1 E4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Adora1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730818
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.