Kif5c (kinesin family member 5C) - Rat Genome Database

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Gene: Kif5c (kinesin family member 5C) Mus musculus
Analyze
Symbol: Kif5c
Name: kinesin family member 5C
RGD ID: 1318371
MGI Page MGI
Description: Predicted to enable several functions, including ATP hydrolysis activity; apolipoprotein receptor binding activity; and plus-end-directed microtubule motor activity. Involved in mRNA transport. Acts upstream of or within motor neuron axon guidance. Located in several cellular components, including axonal growth cone; ciliary rootlet; and neuronal cell body. Is expressed in several structures, including genitourinary system; nervous system; nose; and retina. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 2 and schizophrenia. Orthologous to human KIF5C (kinesin family member 5C).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Khc; kinesin heavy chain isoform 5C; kinesin heavy chain member 5C; kinesin heavy chain neuron-specific 2; kinesin-1; KINN; NKHC; NKHC2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39249,509,298 - 49,664,790 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl249,509,310 - 49,664,790 (+)EnsemblGRCm39 Ensembl
GRCm38249,619,286 - 49,774,778 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl249,619,298 - 49,774,778 (+)EnsemblGRCm38mm10GRCm38
MGSCv37249,474,834 - 49,630,298 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36249,441,323 - 49,596,787 (+)NCBIMGSCv36mm8
Celera251,292,276 - 51,447,919 (+)NCBICelera
Cytogenetic Map2C1.1NCBI
cM Map228.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (EXP)
8-Br-cAMP  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
azoxystrobin  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Brodifacoum  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
chlordecone  (EXP)
choline  (EXP)
cisplatin  (ISO)
clozapine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
deguelin  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
enzalutamide  (ISO)
ethanol  (EXP)
fenpyroximate  (ISO)
folic acid  (EXP)
haloperidol  (ISO)
L-methionine  (EXP)
lead(0)  (ISO)
manganese(II) chloride  (ISO)
methoxychlor  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
N,N-diethyl-m-toluamide  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
pentanal  (ISO)
permethrin  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP)
poly(I:C)  (ISO)
potassium chromate  (ISO)
propanal  (ISO)
pyrimidifen  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (ISO)
sunitinib  (ISO)
tebufenpyrad  (ISO)
tert-butyl hydroperoxide  (ISO)
trichostatin A  (ISO)
triticonazole  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Expression profiling of the cellular processes in uterine leiomyomas: omic approaches and IGF-2 association with leiomyosarcomas. Bae SM, etal., Cancer Res Treat. 2004 Feb;36(1):31-42. doi: 10.4143/crt.2004.36.1.31. Epub 2004 Feb 29.
2. Genetic modifiers and subtypes in schizophrenia: investigations of age at onset, severity, sex and family history. Bergen SE, etal., Schizophr Res. 2014 Apr;154(1-3):48-53. doi: 10.1016/j.schres.2014.01.030. Epub 2014 Feb 26.
3. Kinesin expression in the central nervous system of humans and transgenic hSOD1G93A mice with amyotrophic lateral sclerosis. Kuzma-Kozakiewicz M, etal., Neurodegener Dis. 2013;12(2):71-80. doi: 10.1159/000339529. Epub 2012 Sep 21.
4. Regulation of mitochondrial transport in neurons. Lin MY and Sheng ZH, Exp Cell Res. 2015 May 15;334(1):35-44. doi: 10.1016/j.yexcr.2015.01.004. Epub 2015 Jan 19.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis. Sepulveda-Falla D, etal., J Clin Invest. 2014 Apr;124(4):1552-67. doi: 10.1172/JCI66407. Epub 2014 Feb 24.
Additional References at PubMed
PMID:7528108   PMID:8889548   PMID:9275178   PMID:9782088   PMID:10349636   PMID:10602484   PMID:10964943   PMID:11042159   PMID:11076861   PMID:11163259   PMID:11217851   PMID:11319135  
PMID:11553612   PMID:11707394   PMID:11986669   PMID:12106288   PMID:12465718   PMID:12466851   PMID:12477932   PMID:15226823   PMID:15312650   PMID:15834408   PMID:16018997   PMID:16141072  
PMID:16141073   PMID:16301330   PMID:16783646   PMID:16959763   PMID:17693257   PMID:17887960   PMID:18287559   PMID:19228596   PMID:19608740   PMID:20019668   PMID:20114047   PMID:21267068  
PMID:21335237   PMID:21677750   PMID:21750526   PMID:21768290   PMID:21873635   PMID:21976701   PMID:22794259   PMID:22902294   PMID:23121659   PMID:24286867   PMID:24639525   PMID:24906954  
PMID:24952961   PMID:25352669   PMID:25777528   PMID:25885434   PMID:27507650   PMID:28355567   PMID:28671696   PMID:30068641   PMID:30132979   PMID:30409884   PMID:32325033   PMID:33137126  
PMID:33601422   PMID:34260917   PMID:34321999   PMID:34372599   PMID:34936461   PMID:34966180  


Genomics

Comparative Map Data
Kif5c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39249,509,298 - 49,664,790 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl249,509,310 - 49,664,790 (+)EnsemblGRCm39 Ensembl
GRCm38249,619,286 - 49,774,778 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl249,619,298 - 49,774,778 (+)EnsemblGRCm38mm10GRCm38
MGSCv37249,474,834 - 49,630,298 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36249,441,323 - 49,596,787 (+)NCBIMGSCv36mm8
Celera251,292,276 - 51,447,919 (+)NCBICelera
Cytogenetic Map2C1.1NCBI
cM Map228.68NCBI
KIF5C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382148,875,227 - 149,026,759 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2148,875,227 - 149,026,759 (+)EnsemblGRCh38hg38GRCh38
GRCh372149,632,796 - 149,883,273 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362149,349,289 - 149,396,266 (+)NCBINCBI36Build 36hg18NCBI36
Build 362149,502,042 - 149,591,519 (+)NCBINCBI36Build 36hg18NCBI36
Celera2143,347,002 - 143,497,189 (+)NCBICelera
Cytogenetic Map2q23.1-q23.2NCBI
HuRef2141,692,099 - 141,781,519 (+)NCBIHuRef
HuRef2141,630,811 - 141,685,094 (+)NCBIHuRef
CHM1_12149,799,659 - 149,889,137 (+)NCBICHM1_1
CHM1_12149,638,662 - 149,692,791 (+)NCBICHM1_1
T2T-CHM13v2.02149,325,585 - 149,477,131 (+)NCBIT2T-CHM13v2.0
Kif5c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8354,441,266 - 54,591,630 (+)NCBIGRCr8
mRatBN7.2334,032,082 - 34,185,597 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl334,032,105 - 34,182,413 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx337,402,568 - 37,553,043 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0345,987,291 - 46,137,761 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0343,799,352 - 43,950,019 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0335,014,157 - 35,257,417 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl335,014,538 - 35,257,407 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0340,150,177 - 40,380,889 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4330,602,210 - 30,755,482 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1330,498,932 - 30,637,511 (+)NCBI
Celera332,217,717 - 32,366,850 (+)NCBICelera
Cytogenetic Map3q12NCBI
Kif5c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544014,754,639 - 14,854,406 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544014,754,931 - 14,854,090 (+)NCBIChiLan1.0ChiLan1.0
KIF5C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21325,901,834 - 26,053,898 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B25,916,801 - 26,068,844 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B10,836,356 - 10,987,683 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B153,235,329 - 153,387,221 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B153,235,329 - 153,387,221 (+)Ensemblpanpan1.1panPan2
KIF5C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11950,535,622 - 50,684,485 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1950,535,456 - 50,668,738 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1950,659,035 - 50,807,788 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01952,008,886 - 52,158,206 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1952,008,672 - 52,154,871 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11950,652,619 - 50,801,801 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01950,787,472 - 50,935,851 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01952,186,427 - 52,334,911 (+)NCBIUU_Cfam_GSD_1.0
Kif5c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303113,186,109 - 113,337,599 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646928,280,095 - 28,431,695 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646928,282,921 - 28,431,638 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KIF5C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl153,190,343 - 3,361,410 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1153,190,341 - 3,361,470 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2152,730,440 - 2,901,563 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KIF5C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11034,285,048 - 34,441,918 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1034,285,037 - 34,444,863 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040165,078,867 - 165,231,441 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kif5c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248661,526,638 - 1,698,301 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248661,526,647 - 1,698,113 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Kif5c
5336 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2357
Count of miRNA genes:850
Interacting mature miRNAs:1157
Transcripts:ENSMUST00000028102, ENSMUST00000127245, ENSMUST00000132968, ENSMUST00000138834, ENSMUST00000146247, ENSMUST00000152353
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
8552707Cia23_mcollagen induced arthritis QTL 23 (mouse)Not determined21212953766556453Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1301376Etohc1_methanol consumption 1 (mouse)Not determined22112972555129871Mouse
4141708Pbwg1.2_mpostnatal body weight growth 1.2 (mouse)Not determined2112972555129871Mouse
13463470Tubisq1_mtubulointerstitial injury severity, QTL 1 (mouse)22368914557689269Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
26884438Sklq12_mskull length QTL 12, 16 week (mouse)22459001254890012Mouse
4142130Pgis2_mproteoglycan induced spondylitis 2 (mouse)Not determined22530805156971811Mouse
12904005Cfq2_mconditioned fear QTL 2 (mouse)22702264256396228Mouse
1300577Capsq1_mcapsaicin sensitivity related QTL 1 (mouse)Not determined22760206084013384Mouse
14746979Manh51_mmandible shape 51 (mouse)22896112962961129Mouse
14746997Mancz2_mmandible centroid size 2 (mouse)22896112962961129Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
13464253Ifvrq1_minfluenza virus resistance QTL 1 (mouse)23303449252034492Mouse
4142447Pbwg1.7_mpostnatal body weight growth 1.7 (mouse)Not determined3579732469797406Mouse
4141186Pbwg1.8_mpostnatal body weight growth 1.8 (mouse)Not determined3579732469797406Mouse
4142133Pbwg1.6_mpostnatal body weight growth 1.6 (mouse)Not determined3579732469797406Mouse
1559001Eae33_mexperimental allergic encephalomyelitis susceptibility 33 (mouse)Not determined23599167971609412Mouse
10449151Hdl8_mhigh density lipoprotein (HDL) level 8 (mouse)23812972567072607Mouse
10449150Pvldlc1_mplasma VLDL-cholesterol 1 (mouse)23812972567072607Mouse
10449145Lanq1_mlanosterol level QTL 1 (mouse)23812972567072607Mouse
11038703Ltpr1_mLeishmania tropica response 1 (mouse)23997166573971811Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240885493114910165Mouse
1301480Pbwg1_mpostnatal body weight growth 1 (mouse)Not determined24182071975820843Mouse
4141069Pbwg1.5_mpostnatal body weight growth 1.5 (mouse)Not determined4352061277520756Mouse
1300788Cia2_mcollagen induced arthritis QTL 2 (mouse)Not determined24352061277520756Mouse
1300671Cia4_mcollagen induced arthritis QTL 4 (mouse)Not determined24352061277520756Mouse
1301402Ap2q_malcohol preference 2 QTL (mouse)Not determined24352061277520756Mouse
1301411Pitm1_mprion incubation time 1 (mouse)Not determined24352061277520756Mouse
10755532Lymph5_mlymphocyte differential 5 (mouse)24419901778199017Mouse
1300645Alcp1_malcohol preference locus 1 (mouse)Not determined24522812867838868Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
11532740Pbwg1.10_mpostnatal body weight growth 1.10 (mouse)24813241282132495Mouse
1558820Moo1_mmodifier of Odc1 (mouse)Not determined174826974682269934Mouse
1301747Eae21_mexperimental allergic encephalomyelitis 21 (mouse)Not determined24826974682269934Mouse
1301235Alcw4_malcohol withdrawal 4 (mouse)Not determined24826974682269934Mouse
1300568Hdl1_mhigh density lipoprotein (HDL) level 1 (mouse)Not determined24826974682269934Mouse

Markers in Region
RH142275  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38249,774,335 - 49,774,496UniSTSGRCm38
MGSCv37249,629,855 - 49,630,016UniSTSGRCm37
Celera251,447,476 - 51,447,637UniSTS
Cytogenetic Map2CUniSTS
cM Map232.5UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000028102   ⟹   ENSMUSP00000028102
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl249,509,310 - 49,664,790 (+)Ensembl
GRCm38.p6 Ensembl249,619,298 - 49,774,778 (+)Ensembl
RefSeq Acc Id: ENSMUST00000127245
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl249,634,537 - 49,647,399 (+)Ensembl
GRCm38.p6 Ensembl249,744,525 - 49,757,387 (+)Ensembl
RefSeq Acc Id: ENSMUST00000132968
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl249,642,202 - 49,648,920 (+)Ensembl
GRCm38.p6 Ensembl249,752,190 - 49,758,908 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138834
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl249,612,579 - 49,625,596 (+)Ensembl
GRCm38.p6 Ensembl249,722,567 - 49,735,584 (+)Ensembl
RefSeq Acc Id: ENSMUST00000146247   ⟹   ENSMUSP00000117370
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl249,590,591 - 49,620,263 (+)Ensembl
GRCm38.p6 Ensembl249,700,579 - 49,730,251 (+)Ensembl
RefSeq Acc Id: ENSMUST00000152353
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl249,622,623 - 49,625,587 (+)Ensembl
GRCm38.p6 Ensembl249,732,611 - 49,735,575 (+)Ensembl
RefSeq Acc Id: NM_008449   ⟹   NP_032475
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39249,509,298 - 49,664,790 (+)NCBI
GRCm38249,619,286 - 49,774,778 (+)NCBI
MGSCv37249,474,834 - 49,630,298 (+)RGD
Celera251,292,276 - 51,447,919 (+)RGD
cM Map2 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_032475   ⟸   NM_008449
- UniProtKB: Q6NXI9 (UniProtKB/Swiss-Prot),   Q9Z2F8 (UniProtKB/Swiss-Prot),   P28738 (UniProtKB/Swiss-Prot),   Q3TY51 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000028102   ⟸   ENSMUST00000028102
RefSeq Acc Id: ENSMUSP00000117370   ⟸   ENSMUST00000146247
Protein Domains
Kinesin motor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P28738-F1-model_v2 AlphaFold P28738 1-956 view protein structure

Promoters
RGD ID:6831665
Promoter ID:MM_KWN:29148
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Spleen
Transcripts:ENSMUST00000112714,   OTTMUST00000029661
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36249,474,596 - 49,475,096 (+)MPROMDB
RGD ID:6831667
Promoter ID:MM_KWN:29151
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000029862
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36249,578,141 - 49,578,641 (+)MPROMDB
RGD ID:6831666
Promoter ID:MM_KWN:29152
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000029863
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36249,588,041 - 49,588,541 (+)MPROMDB
RGD ID:6831668
Promoter ID:MM_KWN:29153
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain
Transcripts:OTTMUST00000029864
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36249,599,351 - 49,600,242 (+)MPROMDB
RGD ID:6831670
Promoter ID:MM_KWN:29154
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000029865
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36249,607,791 - 49,608,291 (+)MPROMDB
RGD ID:6847664
Promoter ID:MM_ACW:28277
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:KIF5C.ESEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36249,612,826 - 49,613,326 (+)MPROMDB
RGD ID:6877272
Promoter ID:EPDNEW_M2087
Type:initiation region
Name:Kif5c_1
Description:Mus musculus kinesin family member 5C , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38249,619,305 - 49,619,365EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1098269 AgrOrtholog
Ensembl Genes ENSMUSG00000026764 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000028102 ENTREZGENE
  ENSMUST00000028102.14 UniProtKB/Swiss-Prot
  ENSMUST00000146247.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.850.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.250.1590 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Kinesin-like_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin_motor_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin_motor_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16574 UniProtKB/Swiss-Prot
MGD MGI:1098269 ENTREZGENE
NCBI Gene 16574 ENTREZGENE
PANTHER CENTROMERE PROTEIN E UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KINESIN-LIKE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Kinesin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Kif5c PhenoGen
PRINTS KINESINHEAVY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE KINESIN_MOTOR_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KINESIN_MOTOR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART KISc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2ARD4_MOUSE UniProtKB/TrEMBL
  KIF5C_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TY51 ENTREZGENE, UniProtKB/TrEMBL
  Q6NXI9 ENTREZGENE
  Q9Z2F8 ENTREZGENE
UniProt Secondary Q6NXI9 UniProtKB/Swiss-Prot
  Q9Z2F8 UniProtKB/Swiss-Prot