Homer1 (homer scaffolding protein 1) - Rat Genome Database

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Gene: Homer1 (homer scaffolding protein 1) Mus musculus
Analyze
Symbol: Homer1
Name: homer scaffolding protein 1
RGD ID: 737500
MGI Page MGI
Description: Predicted to enable several functions, including scaffold protein binding activity; transmembrane transporter binding activity; and type 5 metabotropic glutamate receptor binding activity. Predicted to be a structural constituent of postsynapse. Involved in regulation of ion transport and regulation of postsynaptic neurotransmitter receptor activity. Acts upstream of or within several processes, including behavioral response to cocaine; chemical homeostasis within a tissue; and skeletal muscle fiber development. Located in several cellular components, including apical part of cell; myofibril; and postsynaptic density. Is active in glutamatergic synapse and postsynaptic cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human HOMER1 (homer scaffold protein 1); PARTICIPATES IN glutamate signaling pathway; INTERACTS WITH (S)-amphetamine; (S)-nicotine; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: homer homolog 1; homer protein homolog 1; homer, neuronal immediate early gene, 1; homer-1; immediate early gene protein Homer1A; PSD-Z; PSD-Zip45; SYN47; VASP/Ena-related gene up-regulated during seizure and LTP 1; Ves; Ves-1; vesl-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391393,440,265 - 93,549,471 (+)NCBIGRCm39mm39
GRCm39 Ensembl1393,436,143 - 93,541,637 (+)Ensembl
GRCm381393,303,757 - 93,405,129 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1393,299,635 - 93,405,129 (+)EnsemblGRCm38mm10GRCm38
MGSCv371394,074,450 - 94,174,917 (+)NCBIGRCm37mm9NCBIm37
MGSCv361394,405,552 - 94,504,882 (+)NCBImm8
Celera1396,912,321 - 97,012,695 (+)NCBICelera
Cytogenetic Map13C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-amphetamine  (EXP)
(S)-nicotine  (EXP)
1,2,4-trimethylbenzene  (ISO)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bexarotene  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
carbon nanotube  (EXP)
chaetocin  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clozapine  (ISO)
cocaine  (EXP,ISO)
crocidolite asbestos  (EXP)
cyclic ADP-ribose  (ISO)
cyclosporin A  (ISO)
D-cycloserine  (ISO)
dantrolene  (EXP)
dexamethasone  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
fluoxetine  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
glycidol  (ISO)
haloperidol  (ISO)
halothane  (EXP)
hexachlorophene  (EXP)
hydrogen peroxide  (ISO)
isoprenaline  (ISO)
kainic acid  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
linalool  (ISO)
lipopolysaccharide  (ISO)
methamphetamine  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylphenidate  (ISO)
morphine  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
naphthalenes  (ISO)
nefazodone  (ISO)
nickel sulfate  (ISO)
nicotine  (EXP)
oxycodone  (ISO)
paracetamol  (ISO)
phenobarbital  (EXP,ISO)
phenylephrine  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
ranitidine  (ISO)
risperidone  (ISO)
ryanodine  (EXP)
SCH 23390  (ISO)
scopolamine  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetradecane  (ISO)
toluene  (ISO)
undecane  (ISO)
valproic acid  (ISO)
vincaleukoblastine  (ISO)
vinclozolin  (ISO)
vitamin E  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:9808459   PMID:10349636   PMID:10493740   PMID:10851183   PMID:10862698   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11418862   PMID:11684349   PMID:11756499   PMID:12176012  
PMID:12379179   PMID:12466851   PMID:12473083   PMID:12477932   PMID:12653978   PMID:12812750   PMID:12860966   PMID:14505576   PMID:14610273   PMID:14660561   PMID:14681479   PMID:15116392  
PMID:15294147   PMID:15579147   PMID:16011574   PMID:16141072   PMID:16141073   PMID:16226241   PMID:16354916   PMID:16407107   PMID:16602821   PMID:16715092   PMID:16734773   PMID:16855097  
PMID:16944949   PMID:16959763   PMID:17196693   PMID:17355963   PMID:17553998   PMID:18077435   PMID:18171722   PMID:18218901   PMID:18268005   PMID:18982121   PMID:19265511   PMID:19426165  
PMID:19443779   PMID:19845142   PMID:20305784   PMID:21144999   PMID:21172614   PMID:21464775   PMID:21558424   PMID:21595930   PMID:21664258   PMID:21773966   PMID:21795692   PMID:21813671  
PMID:21873635   PMID:21884752   PMID:22267161   PMID:22457511   PMID:22532843   PMID:22561452   PMID:23054826   PMID:23406666   PMID:23447597   PMID:23658151   PMID:23791195   PMID:23911326  
PMID:24167026   PMID:24465821   PMID:24530450   PMID:24554721   PMID:24591653   PMID:24613359   PMID:24722299   PMID:24952961   PMID:25402856   PMID:25409593   PMID:25684310   PMID:25740522  
PMID:25924704   PMID:25982087   PMID:26247728   PMID:26247862   PMID:26496610   PMID:26670047   PMID:27075036   PMID:27160897   PMID:27185486   PMID:27396622   PMID:27480238   PMID:27507650  
PMID:27565344   PMID:27707798   PMID:27999308   PMID:28134614   PMID:28154077   PMID:28634551   PMID:28671696   PMID:28706196   PMID:28715412   PMID:29111324   PMID:29163080   PMID:29222951  
PMID:29518331   PMID:29804286   PMID:30068389   PMID:30104731   PMID:30335140   PMID:30562941   PMID:30737312   PMID:30867257   PMID:31515109   PMID:31563294   PMID:31682853   PMID:32069266  
PMID:32070057   PMID:32325033   PMID:32581705   PMID:34204449  


Genomics

Comparative Map Data
Homer1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391393,440,265 - 93,549,471 (+)NCBIGRCm39mm39
GRCm39 Ensembl1393,436,143 - 93,541,637 (+)Ensembl
GRCm381393,303,757 - 93,405,129 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1393,299,635 - 93,405,129 (+)EnsemblGRCm38mm10GRCm38
MGSCv371394,074,450 - 94,174,917 (+)NCBIGRCm37mm9NCBIm37
MGSCv361394,405,552 - 94,504,882 (+)NCBImm8
Celera1396,912,321 - 97,012,695 (+)NCBICelera
Cytogenetic Map13C3NCBI
HOMER1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl579,372,636 - 79,514,134 (-)EnsemblGRCh38hg38GRCh38
GRCh38579,372,636 - 79,514,134 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37578,668,459 - 78,809,957 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36578,705,542 - 78,845,456 (-)NCBINCBI36hg18NCBI36
Build 34578,705,542 - 78,845,456NCBI
Celera574,569,550 - 74,709,526 (-)NCBI
Cytogenetic Map5q14.1NCBI
HuRef573,877,773 - 74,017,416 (-)NCBIHuRef
CHM1_1578,102,358 - 78,242,362 (-)NCBICHM1_1
Homer1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2224,542,777 - 24,645,715 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl222,909,569 - 23,009,678 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0222,909,550 - 23,012,303 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0242,106,531 - 42,208,187 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera220,619,882 - 20,720,929 (+)NCBICelera
Cytogenetic Map2q12NCBI
Homer1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542521,644,571 - 21,775,735 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542521,644,577 - 21,774,843 (+)NCBIChiLan1.0ChiLan1.0
HOMER1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1536,065,045 - 36,205,928 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl536,064,665 - 36,205,928 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0535,794,627 - 35,936,111 (+)NCBIMhudiblu_PPA_v0panPan3
HOMER1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1327,395,337 - 27,525,822 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl327,400,839 - 27,523,320 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha328,635,060 - 28,765,722 (+)NCBI
ROS_Cfam_1.0327,314,347 - 27,445,373 (+)NCBI
UMICH_Zoey_3.1327,254,336 - 27,384,769 (+)NCBI
UNSW_CanFamBas_1.0327,231,171 - 27,362,707 (+)NCBI
UU_Cfam_GSD_1.0327,511,836 - 27,642,805 (+)NCBI
Homer1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213183,538,579 - 183,681,403 (+)NCBI
SpeTri2.0NW_0049365497,189,588 - 7,320,117 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HOMER1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl288,122,877 - 88,255,281 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1288,116,664 - 88,253,843 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2289,846,977 - 89,904,301 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2289,987,133 - 89,996,112 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HOMER1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1473,591,105 - 73,729,680 (-)NCBI
ChlSab1.1 Ensembl473,589,495 - 73,728,353 (-)Ensembl
Vero_WHO_p1.0NW_02366604922,438,015 - 22,576,283 (-)NCBI
Homer1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248693,878,646 - 4,012,211 (-)NCBI

Position Markers
02.MHAa89e2.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381393,366,383 - 93,366,581UniSTSGRCm38
MGSCv371394,136,338 - 94,136,536UniSTSGRCm37
Celera1396,973,968 - 96,974,166UniSTS
Cytogenetic Map13C3UniSTS
Whitehead_YAC13 UniSTS
Homer1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13C3UniSTS
cM Map13 UniSTS
UniSTS:237074  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381393,366,348 - 93,366,573UniSTSGRCm38
MGSCv371394,136,303 - 94,136,528UniSTSGRCm37
Celera1396,973,933 - 96,974,158UniSTS
Cytogenetic Map13C3UniSTS
UniSTS:237075  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381393,302,860 - 93,303,060UniSTSGRCm38
MGSCv371394,072,815 - 94,073,015UniSTSGRCm37
Celera1396,910,744 - 96,910,944UniSTS
Cytogenetic Map13C3UniSTS
AF093257  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381393,356,481 - 93,356,601UniSTSGRCm38
MGSCv371394,126,436 - 94,126,556UniSTSGRCm37
Celera1396,964,092 - 96,964,212UniSTS
Cytogenetic Map13C3UniSTS
Whitehead/MRC_RH13799.72UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20293442112761890Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133587692596102654Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55572541112294569Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55572541112294569Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55572541112294569Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55572541112294569Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356322643105285678Mouse
1357553Cia28_mcollagen induced arthritis 28 (mouse)Not determined135648143696102654Mouse
1300941Skl6_mskeletal size (tail length) 6 (mouse)Not determined136410270298102826Mouse
1301949Skull20_mskull morphology 20 (mouse)Not determined136410270298102826Mouse
1301445Listr2_mlisteriosis resistance 2 (mouse)Not determined1366596482100596627Mouse
1301593Heal8_mwound healing/regeneration 8 (mouse)Not determined1367905880101906000Mouse
14696726Kidrq3_mkidney weight, right QTL 3 (mouse)1368068947102068947Mouse
14747007Mancz11_mmandible centroid size 11 (mouse)1369963165103963165Mouse
4141266Mol3_mmodifier of LPS-response 3 (mouse)Not determined75984481112294569Mouse
1301610Dps1_mdelta power in slow-wave sleep 1 (mouse)Not determined137704774395594386Mouse
12880414V125Dq10_mvitamin D active form serum level QTL 10 (mouse)1377900000111900000Mouse
10045623Heal18_mwound healing regeneration 18 (mouse)Not determined1379102537113102654Mouse
1558741Ses10_msalmonella enteritidis susceptibility 10 (mouse)Not determined1382603460116603598Mouse
4142465Pbwg17_mpostnatal body weight growth 17 (mouse)Not determined1383739552117739748Mouse
14700691Cisaq1_mcoxsackieviral infection serum ALT QTL 1 (mouse)1386000000120000000Mouse
4140995Fbtq6_mfemoral bone trait QTL 6 (mouse)Not determined1386205109120205250Mouse
4141728Egaq4_mearly growth adjusted QTL 4 (mouse)Not determined87753866112294569Mouse
1300939Hrtfm6_mheart failure modifier 6 (mouse)Not determined1391247158120421639Mouse
1300876Tanidd2_mtally ho associated non-insulin dependednt diabetes mellitus 2 (mouse)Not determined1391828769120421639Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3620
Count of miRNA genes:863
Interacting mature miRNAs:1186
Transcripts:ENSMUST00000060490, ENSMUST00000079086, ENSMUST00000080127, ENSMUST00000102752, ENSMUST00000109492, ENSMUST00000109493, ENSMUST00000109494, ENSMUST00000109495, ENSMUST00000109496, ENSMUST00000109497, ENSMUST00000109498
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001284189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001347598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_147176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_152134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036158052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036158053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB019478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB019479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB089435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB093540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB093542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB093543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC120347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC154231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF093257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF093258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF425674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY137385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB448191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC064041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY644449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ130737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ133579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000060490   ⟹   ENSMUSP00000050471
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1393,305,159 - 93,403,790 (+)Ensembl
RefSeq Acc Id: ENSMUST00000079086   ⟹   ENSMUSP00000078093
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1393,308,034 - 93,405,129 (+)Ensembl
RefSeq Acc Id: ENSMUST00000080127   ⟹   ENSMUSP00000079026
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1393,304,799 - 93,403,681 (+)Ensembl
RefSeq Acc Id: ENSMUST00000102752   ⟹   ENSMUSP00000099813
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1393,304,495 - 93,360,462 (+)Ensembl
RefSeq Acc Id: ENSMUST00000109492   ⟹   ENSMUSP00000105118
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1393,305,184 - 93,367,134 (+)Ensembl
RefSeq Acc Id: ENSMUST00000109493   ⟹   ENSMUSP00000105119
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1393,304,102 - 93,367,134 (+)Ensembl
RefSeq Acc Id: ENSMUST00000109494   ⟹   ENSMUSP00000105120
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1393,303,757 - 93,386,744 (+)Ensembl
RefSeq Acc Id: ENSMUST00000109495   ⟹   ENSMUSP00000105121
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1393,305,278 - 93,402,306 (+)Ensembl
RefSeq Acc Id: ENSMUST00000109496   ⟹   ENSMUSP00000105122
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1393,305,278 - 93,402,306 (+)Ensembl
RefSeq Acc Id: ENSMUST00000109497   ⟹   ENSMUSP00000105123
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1393,305,103 - 93,402,270 (+)Ensembl
RefSeq Acc Id: ENSMUST00000109498   ⟹   ENSMUSP00000105124
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1393,305,103 - 93,402,270 (+)Ensembl
RefSeq Acc Id: ENSMUST00000220609
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1393,299,635 - 93,341,912 (+)Ensembl
RefSeq Acc Id: NM_001284189   ⟹   NP_001271118
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391393,440,265 - 93,541,637 (+)NCBI
GRCm381393,303,757 - 93,405,129 (+)NCBI
Celera1396,912,321 - 97,012,862 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001347598   ⟹   NP_001334527
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391393,440,265 - 93,503,811 (+)NCBI
GRCm381393,303,757 - 93,367,303 (+)NCBI
Sequence:
RefSeq Acc Id: NM_011982   ⟹   NP_036112
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391393,440,265 - 93,493,393 (+)NCBI
GRCm381393,303,757 - 93,356,885 (+)NCBI
MGSCv371394,074,450 - 94,174,917 (+)RGD
Celera1396,912,321 - 97,012,862 (+)NCBI
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_147176   ⟹   NP_671705
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391393,440,265 - 93,541,637 (+)NCBI
GRCm381393,303,757 - 93,405,129 (+)NCBI
MGSCv371394,074,450 - 94,174,917 (+)RGD
Celera1396,912,321 - 97,012,862 (+)NCBI
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_152134   ⟹   NP_687036
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391393,444,542 - 93,541,637 (+)NCBI
GRCm381393,308,034 - 93,405,129 (+)NCBI
MGSCv371394,074,450 - 94,174,917 (+)RGD
Celera1396,912,321 - 97,012,862 (+)NCBI
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036158052   ⟹   XP_036013945
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391393,442,045 - 93,549,471 (+)NCBI
RefSeq Acc Id: XM_036158053   ⟹   XP_036013946
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391393,442,045 - 93,503,642 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_671705   ⟸   NM_147176
- Peptide Label: isoform L
- UniProtKB: Q9Z2Y3 (UniProtKB/Swiss-Prot),   Q3UVL6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_036112   ⟸   NM_011982
- Peptide Label: isoform S
- UniProtKB: Q9Z2Y3 (UniProtKB/Swiss-Prot),   Q5D052 (UniProtKB/TrEMBL),   Q3UVL6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_687036   ⟸   NM_152134
- Peptide Label: isoform d
- UniProtKB: Q9Z2Y3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001271118   ⟸   NM_001284189
- Peptide Label: isoform b
- UniProtKB: Q9Z2Y3 (UniProtKB/Swiss-Prot),   Q3UVL6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001334527   ⟸   NM_001347598
- Peptide Label: isoform M
- UniProtKB: Q9Z2Y3 (UniProtKB/Swiss-Prot),   Q3UVL6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000078093   ⟸   ENSMUST00000079086
RefSeq Acc Id: ENSMUSP00000105120   ⟸   ENSMUST00000109494
RefSeq Acc Id: ENSMUSP00000105121   ⟸   ENSMUST00000109495
RefSeq Acc Id: ENSMUSP00000105118   ⟸   ENSMUST00000109492
RefSeq Acc Id: ENSMUSP00000105119   ⟸   ENSMUST00000109493
RefSeq Acc Id: ENSMUSP00000105124   ⟸   ENSMUST00000109498
RefSeq Acc Id: ENSMUSP00000105122   ⟸   ENSMUST00000109496
RefSeq Acc Id: ENSMUSP00000105123   ⟸   ENSMUST00000109497
RefSeq Acc Id: ENSMUSP00000050471   ⟸   ENSMUST00000060490
RefSeq Acc Id: ENSMUSP00000079026   ⟸   ENSMUST00000080127
RefSeq Acc Id: ENSMUSP00000099813   ⟸   ENSMUST00000102752
RefSeq Acc Id: XP_036013945   ⟸   XM_036158052
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036013946   ⟸   XM_036158053
- Peptide Label: isoform X2
Protein Domains
WH1

Promoters
RGD ID:8681002
Promoter ID:EPDNEW_M18532
Type:initiation region
Name:Homer1_2
Description:Mus musculus homer scaffolding protein 1 , transcript variantd, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18533  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381393,304,546 - 93,304,606EPDNEW
RGD ID:8681004
Promoter ID:EPDNEW_M18533
Type:initiation region
Name:Homer1_1
Description:Mus musculus homer scaffolding protein 1 , transcript variantd, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18532  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381393,308,024 - 93,308,084EPDNEW
RGD ID:6824081
Promoter ID:MM_KWN:14912
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:AK039059_A230091C14RIK,   ENSMUST00000109492,   ENSMUST00000109493,   ENSMUST00000109494,   ENSMUST00000109495,   ENSMUST00000109496,   ENSMUST00000109497,   ENSMUST00000109498,   NM_147176,   OTTMUST00000039265,   UC007RLD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361394,071,231 - 94,074,192 (+)MPROMDB
RGD ID:6824057
Promoter ID:MM_KWN:14914
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:ENSMUST00000109489,   ENSMUST00000109490
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361394,110,921 - 94,111,421 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1347345 AgrOrtholog
Ensembl Genes ENSMUSG00000007617 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000050471 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000078093 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000079026 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000099813 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000105118 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000105119 UniProtKB/TrEMBL
  ENSMUSP00000105120 UniProtKB/TrEMBL
  ENSMUSP00000105121 UniProtKB/TrEMBL
  ENSMUSP00000105122 UniProtKB/TrEMBL
  ENSMUSP00000105123 UniProtKB/TrEMBL
  ENSMUSP00000105124 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000060490 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000079086 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000080127 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000102752 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000109492 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000109493 UniProtKB/TrEMBL
  ENSMUST00000109494 UniProtKB/TrEMBL
  ENSMUST00000109495 UniProtKB/TrEMBL
  ENSMUST00000109496 UniProtKB/TrEMBL
  ENSMUST00000109497 UniProtKB/TrEMBL
  ENSMUST00000109498 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Homer_EVH1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH1/EVH1_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:26556 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1347345 ENTREZGENE
NCBI Gene 26556 ENTREZGENE
Pfam WH1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB HOMER1 RGD
PhenoGen Homer1 PhenoGen
PROSITE WH1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART WH1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3Z6A7_MOUSE UniProtKB/TrEMBL
  D3Z6A8_MOUSE UniProtKB/TrEMBL
  D3Z6A9_MOUSE UniProtKB/TrEMBL
  E9Q0I7_MOUSE UniProtKB/TrEMBL
  E9Q0I8_MOUSE UniProtKB/TrEMBL
  HOME1_MOUSE UniProtKB/Swiss-Prot
  Q3UVL6 ENTREZGENE, UniProtKB/TrEMBL
  Q5D052 ENTREZGENE, UniProtKB/TrEMBL
  Q8C655_MOUSE UniProtKB/TrEMBL
  Q8VIL7_MOUSE UniProtKB/TrEMBL
  Q8VIL8_MOUSE UniProtKB/TrEMBL
  Q9Z2Y3 ENTREZGENE
UniProt Secondary Q8K3E1 UniProtKB/Swiss-Prot
  Q8K4M8 UniProtKB/Swiss-Prot
  Q9Z0E9 UniProtKB/Swiss-Prot
  Q9Z216 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-29 Homer1  homer scaffolding protein 1    homer homolog 1 (Drosophila)  Symbol and/or name change 5135510 APPROVED