Dynlt3 (dynein light chain Tctex-type 3) - Rat Genome Database

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Gene: Dynlt3 (dynein light chain Tctex-type 3) Mus musculus
Analyze
Symbol: Dynlt3
Name: dynein light chain Tctex-type 3
RGD ID: 1556957
MGI Page MGI
Description: Predicted to enable dynein intermediate chain binding activity and identical protein binding activity. Predicted to be involved in microtubule-based movement and positive regulation of mitotic cell cycle. Predicted to be located in mitotic spindle astral microtubule. Predicted to be part of cytoplasmic dynein complex. Predicted to be active in cytoplasm. Predicted to colocalize with kinetochore. Is expressed in several structures, including central nervous system; gut; lower urinary tract; nose; and submandibular gland primordium. Orthologous to human DYNLT3 (dynein light chain Tctex-type 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2310075M16Rik; AU042796; protein 91/23; T-complex associated-testis-expressed 1-like; T-complex-associated testis-expressed 1-like; t-complex-associated-testis-expressed 1-like; Tcte1; Tcte1l; vt-complex-associated-testis-expressed 1-like
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X9,520,509 - 9,529,222 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX9,520,506 - 9,529,242 (-)EnsemblGRCm39 Ensembl
GRCm38X9,654,270 - 9,662,983 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX9,654,267 - 9,663,003 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X9,231,396 - 9,240,109 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X8,811,229 - 8,819,942 (-)NCBIMGSCv36mm8
CeleraX7,370,355 - 7,379,067 (-)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX4.47NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Cytoplasmic dynein. Allan VJ, Biochem Soc Trans. 2011 Oct;39(5):1169-78. doi: 10.1042/BST0391169.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12559582   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16260502  
PMID:16800626   PMID:17289665   PMID:21267068   PMID:21471385   PMID:21693773   PMID:21873635   PMID:22028875   PMID:24498314   PMID:29111324   PMID:32325033   PMID:33772156   PMID:36973253  


Genomics

Comparative Map Data
Dynlt3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X9,520,509 - 9,529,222 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX9,520,506 - 9,529,242 (-)EnsemblGRCm39 Ensembl
GRCm38X9,654,270 - 9,662,983 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX9,654,267 - 9,663,003 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X9,231,396 - 9,240,109 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X8,811,229 - 8,819,942 (-)NCBIMGSCv36mm8
CeleraX7,370,355 - 7,379,067 (-)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX4.47NCBI
DYNLT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X37,838,836 - 37,847,571 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX37,836,757 - 37,847,571 (-)EnsemblGRCh38hg38GRCh38
GRCh37X37,698,089 - 37,706,824 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X37,583,033 - 37,591,775 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X37,454,305 - 37,463,048NCBI
CeleraX41,835,775 - 41,844,575 (-)NCBICelera
Cytogenetic MapXp11.4NCBI
HuRefX35,443,356 - 35,452,111 (-)NCBIHuRef
CHM1_1X37,729,229 - 37,738,029 (-)NCBICHM1_1
T2T-CHM13v2.0X37,242,419 - 37,251,154 (-)NCBIT2T-CHM13v2.0
Dynlt3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X16,000,425 - 16,009,632 (+)NCBIGRCr8
mRatBN7.2X13,327,933 - 13,337,139 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX13,327,892 - 13,337,139 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX13,515,051 - 13,524,263 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X17,011,983 - 17,021,195 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X13,268,568 - 13,277,780 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X14,633,342 - 14,642,356 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX14,633,342 - 14,642,424 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X15,414,610 - 15,423,884 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X25,480,916 - 25,490,479 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX14,088,617 - 14,097,885 (-)NCBICelera
Cytogenetic MapXq12NCBI
Dynlt3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955587827,278 - 838,869 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955587828,730 - 838,614 (-)NCBIChiLan1.0ChiLan1.0
DYNLT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X39,487,750 - 39,496,644 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X39,491,124 - 39,499,945 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X30,289,242 - 30,298,033 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X37,998,059 - 38,006,855 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX37,996,729 - 38,006,855 (-)Ensemblpanpan1.1panPan2
DYNLT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X32,603,881 - 32,611,213 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX32,603,945 - 32,611,542 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX19,951,574 - 19,958,842 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X32,648,884 - 32,656,216 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX32,648,888 - 32,656,545 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X32,730,392 - 32,737,658 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X32,694,273 - 32,701,541 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X32,742,263 - 32,749,531 (-)NCBIUU_Cfam_GSD_1.0
Dynlt3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X24,850,099 - 24,860,957 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365024,690,776 - 4,701,750 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365024,690,810 - 4,701,615 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNLT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX33,711,492 - 33,724,683 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X33,711,993 - 33,724,596 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X37,424,941 - 37,437,546 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DYNLT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366605638,299,966 - 38,308,644 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dynlt3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476217,734,769 - 17,747,527 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476217,734,738 - 17,747,418 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dynlt3
269 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:535
Count of miRNA genes:395
Interacting mature miRNAs:438
Transcripts:ENSMUST00000033519, ENSMUST00000125030, ENSMUST00000140019, ENSMUST00000154091
Prediction methods:Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302195Pbwg10_mpostnatal body weight growth 10 (mouse)Not determinedX126202173Mouse
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse

Markers in Region
AU042796  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X9,654,550 - 9,654,647UniSTSGRCm38
MGSCv37X9,231,676 - 9,231,773UniSTSGRCm37
CeleraX7,370,635 - 7,370,732UniSTS
Cytogenetic MapXA1.1UniSTS
Whitehead/MRC_RHX105.22UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000033519   ⟹   ENSMUSP00000033519
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX9,520,506 - 9,529,242 (-)Ensembl
GRCm38.p6 EnsemblX9,654,267 - 9,663,003 (-)Ensembl
Ensembl Acc Id: ENSMUST00000125030
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX9,522,248 - 9,525,869 (-)Ensembl
GRCm38.p6 EnsemblX9,656,009 - 9,659,630 (-)Ensembl
Ensembl Acc Id: ENSMUST00000140019
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX9,522,577 - 9,523,596 (-)Ensembl
GRCm38.p6 EnsemblX9,656,338 - 9,657,357 (-)Ensembl
Ensembl Acc Id: ENSMUST00000154091
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX9,522,515 - 9,529,242 (-)Ensembl
GRCm38.p6 EnsemblX9,656,276 - 9,663,003 (-)Ensembl
RefSeq Acc Id: NM_025975   ⟹   NP_080251
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X9,520,509 - 9,529,222 (-)NCBI
GRCm38X9,654,270 - 9,662,983 (-)NCBI
MGSCv37X9,231,396 - 9,240,109 (-)RGD
CeleraX7,370,355 - 7,379,067 (-)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NP_080251   ⟸   NM_025975
- UniProtKB: P56387 (UniProtKB/Swiss-Prot),   Q542J7 (UniProtKB/TrEMBL),   Q9D2T5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000033519   ⟸   ENSMUST00000033519

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P56387-F1-model_v2 AlphaFold P56387 1-116 view protein structure

Promoters
RGD ID:6845624
Promoter ID:MM_KWN:59561
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B6
Transcripts:OTTMUST00000041002
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X9,236,301 - 9,236,902 (-)MPROMDB
RGD ID:6845623
Promoter ID:MM_KWN:59562
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000040991,   OTTMUST00000040992
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X9,239,616 - 9,240,116 (-)MPROMDB
RGD ID:13680076
Promoter ID:EPDNEW_M24187
Type:initiation region
Name:Dynlt3_1
Description:Mus musculus dynein light chain Tctex-type 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X9,662,933 - 9,662,993EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1914367 AgrOrtholog
Ensembl Genes ENSMUSG00000031176 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000033519 ENTREZGENE
  ENSMUST00000033519.3 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.1140.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Tctex-1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tctex-1-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:67117 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1914367 ENTREZGENE
NCBI Gene 67117 ENTREZGENE
PANTHER DYNEIN LIGHT CHAIN TCTEX-TYPE 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR21255 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Tctex-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dynlt3 PhenoGen
UniProt DYLT3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q542J7 ENTREZGENE, UniProtKB/TrEMBL
  Q9D2T5 ENTREZGENE, UniProtKB/TrEMBL
  Q9D6M5_MOUSE UniProtKB/TrEMBL