DYNLT3 (dynein light chain Tctex-type 3) - Rat Genome Database

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Gene: DYNLT3 (dynein light chain Tctex-type 3) Homo sapiens
Analyze
Symbol: DYNLT3
Name: dynein light chain Tctex-type 3
RGD ID: 1350586
HGNC Page HGNC:11694
Description: Enables identical protein binding activity. Predicted to be involved in microtubule-based movement and regulation of mitotic cell cycle. Located in kinetochore. Part of cytoplasmic dynein complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: dynein, light chain, Tctex-type 3; protein 91/23; RP3; t-complex-associated-testis-expressed 1-like; TCTE1L; TCTEX1L
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: DYNLT3P1   DYNLT3P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X37,838,836 - 37,847,571 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX37,836,757 - 37,847,571 (-)EnsemblGRCh38hg38GRCh38
GRCh37X37,698,089 - 37,706,824 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X37,583,033 - 37,591,775 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X37,454,305 - 37,463,048NCBI
CeleraX41,835,775 - 41,844,575 (-)NCBICelera
Cytogenetic MapXp11.4NCBI
HuRefX35,443,356 - 35,452,111 (-)NCBIHuRef
CHM1_1X37,729,229 - 37,738,029 (-)NCBICHM1_1
T2T-CHM13v2.0X37,242,419 - 37,251,154 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 11 of 11 rows
Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
DYNLT3Humanautistic disorder  IAGPRGD:143515258554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106|PMID:30208311
DYNLT3HumanMcLeod syndrome  IAGPRGD:4058554198554872ClinVar Annotator: match by term: McLeod neuroacanthocytosis syndromeClinVarPMID:11761473|PMID:13860532|PMID:25934153|PMID:28555782|PMID:30128557
DYNLT3HumanNeurodevelopmental Disorders  IAGPRGD:146982928554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
DYNLT3Humanornithine carbamoyltransferase deficiency  IAGPRGD:268969508554872ClinVar Annotator: match by term: Ornithine carbamoyltransferase deficiencyClinVarPMID:11793468|PMID:18487280|PMID:19138872|PMID:19475717|PMID:19783189|PMID:22382802|PMID:22494545|PMID:28492532
DYNLT3Humanornithine carbamoyltransferase deficiency  IAGPRGD:1564413278554872ClinVar Annotator: match by term: Ornithine carbamoyltransferase deficiencyClinVarPMID:28492532
DYNLT3Humanornithine carbamoyltransferase deficiency  IAGPRGD:1272738528554872ClinVar Annotator: match by term: Ornithine carbamoyltransferase deficiencyClinVarPMID:10946359|PMID:11793468|PMID:16055928|PMID:16786505|PMID:16969763|PMID:18487280|PMID:19138872|PMID:19475717|PMID:19783189|PMID:22382802|PMID:22494545|PMID:28492532
DYNLT3Humanprimary ciliary dyskinesia  IAGPRGD:1272738528554872ClinVar Annotator: match by term: Primary ciliary dyskinesiaClinVarPMID:10946359|PMID:11793468|PMID:16055928|PMID:16786505|PMID:16969763|PMID:18487280|PMID:19138872|PMID:19475717|PMID:19783189|PMID:22382802|PMID:22494545|PMID:28492532
DYNLT3Humanprimary ciliary dyskinesia  IAGPRGD:1269224928554872ClinVar Annotator: match by term: Primary ciliary dyskinesiaClinVarPMID:28492532
DYNLT3Humanretinitis pigmentosa 3  IAGPRGD:385975208554872ClinVar Annotator: match by term: Retinitis pigmentosa 3ClinVar 
DYNLT3Humansyndromic X-linked intellectual disability Lubs type  IAGPRGD:143993378554872ClinVar Annotator: match by term: Syndromic X-linked intellectual disability Lubs typeClinVarPMID:25741868
DYNLT3HumanX-linked chronic granulomatous disease  IAGPRGD:268969198554872ClinVar Annotator: match by term: Granulomatous disease, chronic, X-linkedClinVarPMID:22929960|PMID:27701760|PMID:28492532
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1 to 20 of 83 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
DYNLT3Human(+)-schisandrin B multiple interactionsISORGD:15497556480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of DYNLT3 mRNA]CTDPMID:31150632
DYNLT3Human(-)-alpha-phellandrene increases expressionEXP 6480464alpha phellandrene results in increased expression of DYNLT3 mRNACTDPMID:25075043
DYNLT3Human1,2-dimethylhydrazine decreases expressionISORGD:155695764804641,2-Dimethylhydrazine results in decreased expression of DYNLT3 mRNACTDPMID:22206623
DYNLT3Human1,2-dimethylhydrazine multiple interactionsISORGD:15569576480464[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DYNLT3 mRNACTDPMID:22206623
DYNLT3Human17beta-estradiol multiple interactionsEXP 6480464EGF protein promotes the reaction [Estradiol results in increased expression of DYNLT3 mRNA]CTDPMID:24758408
DYNLT3Human17beta-estradiol decreases expressionISORGD:15569576480464Estradiol results in decreased expression of DYNLT3 mRNACTDPMID:39298647
DYNLT3Human17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of DYNLT3 mRNACTDPMID:24758408|PMID:31614463
DYNLT3Human2,3,7,8-tetrachlorodibenzodioxine decreases expressionISORGD:15497556480464Tetrachlorodibenzodioxin results in decreased expression of DYNLT3 mRNACTDPMID:21215274|PMID:33387578
DYNLT3Human2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:15569576480464Tetrachlorodibenzodioxin results in increased expression of DYNLT3 mRNACTDPMID:15034205
DYNLT3Human2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORGD:15569576480464AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of DYNLT3 mRNA]CTDPMID:15034205
DYNLT3Human2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:15569576480464Tetrachlorodibenzodioxin affects the expression of DYNLT3 mRNACTDPMID:21570461
DYNLT3Human2-hydroxypropanoic acid affects expressionEXP 6480464Lactic Acid affects the expression of DYNLT3 mRNACTDPMID:30851411
DYNLT3Human3-isobutyl-1-methyl-7H-xanthine multiple interactionsEXP 6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ...CTDPMID:28628672
DYNLT3Human4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ...CTDPMID:28628672
DYNLT3Human4-hydroxynon-2-enal affects bindingEXP 6480464DYNLT3 protein binds to 4-hydroxy-2-nonenalCTDPMID:20043646
DYNLT3Humanaflatoxin B1 increases expressionISORGD:15569576480464Aflatoxin B1 results in increased expression of DYNLT3 mRNACTDPMID:19770486
DYNLT3Humanaflatoxin B1 increases expressionISORGD:15497556480464Aflatoxin B1 results in increased expression of DYNLT3 mRNACTDPMID:33354967
DYNLT3Humanalpha-phellandrene increases expressionEXP 6480464alpha phellandrene results in increased expression of DYNLT3 mRNACTDPMID:25075043
DYNLT3Humanantimycin A decreases expressionEXP 6480464Antimycin A results in decreased expression of DYNLT3 mRNACTDPMID:33512557
DYNLT3HumanAroclor 1254 decreases expressionISORGD:15569576480464Chlorodiphenyl (54% Chlorine) results in decreased expression of DYNLT3 mRNACTDPMID:23650126

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Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
DYNLT3Humancell division involved_inIEAUniProtKB-KW:KW-0132150520179 UniProtGO_REF:0000043
DYNLT3Humanmicrotubule-based movement involved_inIBAFB:FBgn0024432|MGI:98642|PANTHER:PTN000478852|PomBase:SPAC1805.08|UniProtKB:Q8WW35150520179 GO_CentralGO_REF:0000033
DYNLT3Humanpositive regulation of mitotic cell cycle  ISORGD:15497559068941 RGDPMID:17289665|REF_RGD_ID:8554144
DYNLT3Humanpositive regulation of mitotic cell cycle involved_inIEAUniProtKB:F7FAB7|UniProtKB:Q5XI90|ensembl:ENSRNOP00000004808150520179 EnsemblGO_REF:0000107
DYNLT3Humanregulation of mitotic cell cycle involved_inISSUniProtKB:Q5XI90150520179 UniProtGO_REF:0000024
DYNLT3Humanregulation of mitotic cell cycle involved_inIEAUniProtKB:Q5XI90|ensembl:ENSRNOP00000004808150520179 EnsemblGO_REF:0000107

Cellular Component
1 to 20 of 21 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
DYNLT3Humanchromosome located_inIEAUniProtKB-KW:KW-0158150520179 UniProtGO_REF:0000043
DYNLT3Humanchromosome, centromeric region located_inIEAUniProtKB-KW:KW-0137150520179 UniProtGO_REF:0000043
DYNLT3Humancytoplasm located_inIEAUniProtKB-KW:KW-0963150520179 UniProtGO_REF:0000043
DYNLT3Humancytoplasm located_inIEAUniProtKB:Q5XI90|ensembl:ENSRNOP00000004808150520179 EnsemblGO_REF:0000107
DYNLT3Humancytoplasm is_active_inIBAMGI:3045358|MGI:98642|MGI:98643|PANTHER:PTN000478852|PomBase:SPAC1805.08|RGD:1549755|UniProtKB:O04355|UniProtKB:P63172|UniProtKB:Q5JR98|UniProtKB:Q8WW35|WB:WBGene00017014150520179 GO_CentralGO_REF:0000033
DYNLT3Humancytoplasmic dynein complex  ISORGD:15497559068941 RGDPMID:17289665|REF_RGD_ID:8554144
DYNLT3Humancytoplasmic dynein complex part_ofIEAUniProtKB:F7FAB7|UniProtKB:Q5XI90|ensembl:ENSRNOP00000004808150520179 EnsemblGO_REF:0000107
DYNLT3Humancytoplasmic dynein complex part_ofIBAMGI:98642|PANTHER:PTN000478852|RGD:1549755|UniProtKB:P51808|UniProtKB:P63171|UniProtKB:P63172|UniProtKB:Q8WW35150520179 GO_CentralGO_REF:0000033
DYNLT3Humancytoplasmic dynein complex part_ofIDA 150520179 PMID:11425878UniProtPMID:11425878
DYNLT3Humancytoskeleton located_inIEAUniProtKB-KW:KW-0206150520179 UniProtGO_REF:0000043
DYNLT3Humancytoskeleton located_inIEAUniProtKB-SubCell:SL-0090150520179 UniProtGO_REF:0000044
DYNLT3Humandynein complex part_ofIEAUniProtKB-KW:KW-0243150520179 UniProtGO_REF:0000043
DYNLT3Humankinetochore located_inIDA 150520179 PMID:17289665UniProtPMID:17289665
DYNLT3Humankinetochore located_inIEAUniProtKB:F7FAB7|UniProtKB:Q5XI90|ensembl:ENSRNOP00000004808150520179 EnsemblGO_REF:0000107
DYNLT3Humankinetochore located_inIEAUniProtKB-KW:KW-0995150520179 UniProtGO_REF:0000043
DYNLT3Humankinetochore  ISORGD:15497559068941 RGDPMID:17289665|REF_RGD_ID:8554144
DYNLT3Humanmicrotubule located_inIEAUniProtKB-KW:KW-0493150520179 UniProtGO_REF:0000043
DYNLT3Humanmitotic spindle astral microtubule  ISORGD:15497559068941 RGDPMID:17289665|REF_RGD_ID:8554144
DYNLT3Humanmitotic spindle astral microtubule located_inIEAUniProtKB:F7FAB7|UniProtKB:Q5XI90|ensembl:ENSRNOP00000004808150520179 EnsemblGO_REF:0000107
DYNLT3Humannucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043
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Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
DYNLT3Humandynein intermediate chain binding enablesIBAFB:FBgn0024432|PANTHER:PTN000478852|UniProtKB:Q8WW35150520179 GO_CentralGO_REF:0000033
DYNLT3Humanidentical protein binding enablesIPIUniProtKB:P51808150520179 PMID:16189514, PMID:25416956, PMID:32296183IntActPMID:16189514|PMID:25416956|PMID:32296183
DYNLT3Humanidentical protein binding enablesIEAUniProtKB:Q5XI90|ensembl:ENSRNOP00000004808150520179 EnsemblGO_REF:0000107
DYNLT3Humanprotein binding enablesIPIUniProtKB:Q13409150520179 PMID:16189514, PMID:31515488, PMID:33961781, PMID:35271311IntActPMID:16189514|PMID:31515488|PMID:33961781|PMID:35271311
DYNLT3Humanprotein binding enablesIPIUniProtKB:P63172150520179 PMID:27173435IntActPMID:27173435
DYNLT3Humanprotein binding enablesIPIUniProtKB:Q9GZT8150520179 PMID:25416956IntActPMID:25416956
DYNLT3Humanprotein binding enablesIPIUniProtKB:P54277-2|UniProtKB:P63172|UniProtKB:Q13409-3|UniProtKB:Q6PJT7-6|UniProtKB:Q8WU43|UniProtKB:Q9NRJ3150520179 PMID:32296183IntActPMID:32296183

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
DYNLT3Humanmitochondria transport pathway  TAS 10402142 RGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
DYNLT3HumanAutism  IAGPRGD:143515258554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106|PMID:30208311

#
Reference Title
Reference Citation
1. Cytoplasmic dynein. Allan VJ, Biochem Soc Trans. 2011 Oct;39(5):1169-78. doi: 10.1042/BST0391169.
2. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:8004092   PMID:9790665   PMID:11425878   PMID:11746667   PMID:12475239   PMID:12477932   PMID:15117959   PMID:15489334   PMID:16079286   PMID:16189514   PMID:16344560   PMID:17289665  
PMID:17676955   PMID:18029348   PMID:20360068   PMID:20668116   PMID:21166973   PMID:21873635   PMID:22863883   PMID:22939629   PMID:24457600   PMID:25416956   PMID:26496610   PMID:27173435  
PMID:28718761   PMID:31515488   PMID:32296183   PMID:32539762   PMID:33637726   PMID:33961781   PMID:35256949   PMID:35271311   PMID:35831314   PMID:36215168   PMID:37260179  



DYNLT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X37,838,836 - 37,847,571 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX37,836,757 - 37,847,571 (-)EnsemblGRCh38hg38GRCh38
GRCh37X37,698,089 - 37,706,824 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X37,583,033 - 37,591,775 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X37,454,305 - 37,463,048NCBI
CeleraX41,835,775 - 41,844,575 (-)NCBICelera
Cytogenetic MapXp11.4NCBI
HuRefX35,443,356 - 35,452,111 (-)NCBIHuRef
CHM1_1X37,729,229 - 37,738,029 (-)NCBICHM1_1
T2T-CHM13v2.0X37,242,419 - 37,251,154 (-)NCBIT2T-CHM13v2.0
Dynlt3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X9,520,509 - 9,529,222 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX9,520,506 - 9,529,242 (-)EnsemblGRCm39 Ensembl
GRCm38X9,654,270 - 9,662,983 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX9,654,267 - 9,663,003 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X9,231,396 - 9,240,109 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X8,811,229 - 8,819,942 (-)NCBIMGSCv36mm8
CeleraX7,370,355 - 7,379,067 (-)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX4.47NCBI
Dynlt3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X16,000,425 - 16,009,632 (+)NCBIGRCr8
mRatBN7.2X13,327,933 - 13,337,139 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX13,327,892 - 13,337,139 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX13,515,051 - 13,524,263 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X17,011,983 - 17,021,195 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X13,268,568 - 13,277,780 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X14,633,342 - 14,642,356 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX14,633,342 - 14,642,424 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X15,414,610 - 15,423,884 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X25,480,916 - 25,490,479 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX14,088,617 - 14,097,885 (-)NCBICelera
Cytogenetic MapXq12NCBI
Dynlt3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955587827,278 - 838,869 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955587828,730 - 838,614 (-)NCBIChiLan1.0ChiLan1.0
DYNLT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X39,487,750 - 39,496,644 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X39,491,124 - 39,499,945 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X30,289,242 - 30,298,033 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X37,998,059 - 38,006,855 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX37,996,729 - 38,006,855 (-)Ensemblpanpan1.1panPan2
DYNLT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X32,603,881 - 32,611,213 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX32,603,945 - 32,611,542 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX19,951,574 - 19,958,842 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X32,648,884 - 32,656,216 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX32,648,888 - 32,656,545 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X32,730,392 - 32,737,658 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X32,694,273 - 32,701,541 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X32,742,263 - 32,749,531 (-)NCBIUU_Cfam_GSD_1.0
Dynlt3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X24,850,099 - 24,860,957 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365024,690,776 - 4,701,750 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365024,690,810 - 4,701,615 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNLT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX33,711,492 - 33,724,683 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X33,711,993 - 33,724,596 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X37,424,941 - 37,437,546 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DYNLT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366605638,299,966 - 38,308,644 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dynlt3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476217,734,769 - 17,747,527 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476217,734,738 - 17,747,418 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in DYNLT3
8 total Variants

Predicted Target Of
Summary Value
Count of predictions:1415
Count of miRNA genes:832
Interacting mature miRNAs:965
Transcripts:ENST00000378578, ENST00000378581, ENST00000432389
Prediction methods:Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597050100GWAS1146174_Huterine fibroid QTL GWAS1146174 (human)0.000007uterine fibroidX3784157537841576Human

DXS7492  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X37,698,130 - 37,698,473UniSTSGRCh37
Build 36X37,583,074 - 37,583,417RGDNCBI36
CeleraX41,835,816 - 41,836,159RGD
Cytogenetic MapXp21UniSTS
HuRefX35,443,397 - 35,443,740UniSTS
Whitehead-YAC Contig MapX UniSTS
RH77891  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372128,957,583 - 128,957,765UniSTSGRCh37
GRCh37X37,699,835 - 37,701,069UniSTSGRCh37
Build 362128,674,053 - 128,674,235RGDNCBI36
CeleraX41,837,521 - 41,838,755UniSTS
Celera2122,264,220 - 122,264,402RGD
Cytogenetic MapXp21UniSTS
HuRef2121,263,861 - 121,264,043UniSTS
HuRefX35,445,102 - 35,446,334UniSTS
RH17973  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X37,698,205 - 37,698,406UniSTSGRCh37
Build 36X37,583,149 - 37,583,350RGDNCBI36
CeleraX41,835,891 - 41,836,092RGD
Cytogenetic MapXp21UniSTS
HuRefX35,443,472 - 35,443,673UniSTS
GDB:342122  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X37,700,999 - 37,701,188UniSTSGRCh37
Build 36X37,585,943 - 37,586,132RGDNCBI36
CeleraX41,838,685 - 41,838,874RGD
Cytogenetic MapXp21UniSTS
HuRefX35,446,264 - 35,446,453UniSTS
DXS1110  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X37,699,886 - 37,700,151UniSTSGRCh37
Build 36X37,584,830 - 37,585,095RGDNCBI36
CeleraX41,837,572 - 41,837,837RGD
Cytogenetic MapXp21UniSTS
HuRefX35,445,153 - 35,445,416UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4971 1726 2350 6 624 1949 465 2268 7304 6470 53 3733 1 852 1743 1616 175 1



Ensembl Acc Id: ENST00000378578   ⟹   ENSP00000367841
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX37,838,836 - 37,847,571 (-)Ensembl
Ensembl Acc Id: ENST00000378581   ⟹   ENSP00000367844
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX37,836,757 - 37,847,514 (-)Ensembl
Ensembl Acc Id: ENST00000432389   ⟹   ENSP00000402695
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX37,840,543 - 37,847,408 (-)Ensembl
RefSeq Acc Id: NM_006520   ⟹   NP_006511
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38X37,838,836 - 37,847,571 (-)NCBI
GRCh37X37,698,089 - 37,706,889 (-)ENTREZGENE
Build 36X37,583,033 - 37,591,775 (-)NCBI Archive
HuRefX35,443,356 - 35,452,111 (-)ENTREZGENE
CHM1_1X37,729,229 - 37,738,029 (-)NCBI
T2T-CHM13v2.0X37,242,419 - 37,251,154 (-)NCBI
Sequence:
1 to 11 of 11 rows
Protein RefSeqs NP_006511 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA57444 (Get FASTA)   NCBI Sequence Viewer  
  AAH00968 (Get FASTA)   NCBI Sequence Viewer  
  BAG34793 (Get FASTA)   NCBI Sequence Viewer  
  CAG29316 (Get FASTA)   NCBI Sequence Viewer  
  CAG47009 (Get FASTA)   NCBI Sequence Viewer  
  CAV30714 (Get FASTA)   NCBI Sequence Viewer  
  EAW59452 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000367841
  ENSP00000367841.4
GenBank Protein P51808 (Get FASTA)   NCBI Sequence Viewer  
1 to 11 of 11 rows
RefSeq Acc Id: NP_006511   ⟸   NM_006520
- UniProtKB: Q6ICS3 (UniProtKB/Swiss-Prot),   P51808 (UniProtKB/Swiss-Prot),   F2Z328 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000367841   ⟸   ENST00000378578
Ensembl Acc Id: ENSP00000367844   ⟸   ENST00000378581
Ensembl Acc Id: ENSP00000402695   ⟸   ENST00000432389

Name Modeler Protein Id AA Range Protein Structure
AF-P51808-F1-model_v2 AlphaFold P51808 1-116 view protein structure

RGD ID:6808644
Promoter ID:HG_KWN:66413
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000378574,   ENST00000378581,   OTTHUMT00000080876
Position:
Human AssemblyChrPosition (strand)Source
Build 36X37,591,574 - 37,592,074 (-)MPROMDB
RGD ID:6853278
Promoter ID:EP74460
Type:initiation region
Name:HS_TCTE1L
Description:T-complex-associated-testis-expressed 1-like.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Mammalian gene collection (MGC) full-length cDNA cloning
Position:
Human AssemblyChrPosition (strand)Source
Build 36X37,591,768 - 37,591,828EPD
RGD ID:13605028
Promoter ID:EPDNEW_H28698
Type:initiation region
Name:DYNLT3_1
Description:dynein light chain Tctex-type 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H28699  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38X37,847,571 - 37,847,631EPDNEW


1 to 23 of 23 rows
Database
Acc Id
Source(s)
COSMIC DYNLT3 COSMIC
Ensembl Genes ENSG00000165169 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000378578 ENTREZGENE
  ENST00000378578.9 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.1140.40 UniProtKB/Swiss-Prot
GTEx ENSG00000165169 GTEx
HGNC ID HGNC:11694 ENTREZGENE
Human Proteome Map DYNLT3 Human Proteome Map
InterPro Tctex-1-like UniProtKB/Swiss-Prot
  Tctex-1-like_sf UniProtKB/Swiss-Prot
KEGG Report hsa:6990 UniProtKB/Swiss-Prot
NCBI Gene 6990 ENTREZGENE
OMIM 300302 OMIM
PANTHER DYNEIN LIGHT CHAIN TCTEX-TYPE 3 UniProtKB/Swiss-Prot
  PTHR21255 UniProtKB/Swiss-Prot
Pfam Tctex-1 UniProtKB/Swiss-Prot
PharmGKB PA36414 PharmGKB
UniProt A6NGJ0_HUMAN UniProtKB/TrEMBL
  DYLT3_HUMAN UniProtKB/Swiss-Prot
  F2Z328 ENTREZGENE, UniProtKB/TrEMBL
  P51808 ENTREZGENE
  Q6ICS3 ENTREZGENE
UniProt Secondary Q6ICS3 UniProtKB/Swiss-Prot
1 to 23 of 23 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-07 DYNLT3  dynein light chain Tctex-type 3    dynein, light chain, Tctex-type 3  Symbol and/or name change 5135510 APPROVED